Best TWAS P=1.18e-08 · Best GWAS P=1.93e-08 conditioned to 0.178
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC100129961 | 0.17 | 0.14 | enet | 9 | 0.14 | 2.6e-17 | 5.2 | 5.2 | 1.6e-07 | -0.51 | 0.01 | 0.99 | FALSE |
| 2 | YFS | Blood | CCNT2 | 0.01 | 0.01 | blup | 363 | 0.01 | 6.3e-05 | -3.3 | -5.1 | 2.9e-07 | 0.64 | 0.26 | 0.58 | FALSE |
| 3 | YFS | Blood | MCM6 | 0.18 | 0.15 | enet | 20 | 0.20 | 8.5e-64 | -5.6 | -5.7 | 1.2e-08 | 0.87 | 0.00 | 1.00 | TRUE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LCT | 0.02 | 0.02 | enet | 3 | 0.03 | 7.6e-07 | -5.6 | 5.3 | 1.1e-07 | -0.95 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LCT | 0.04 | 0.02 | blup | 36 | 0.02 | 1.9e-03 | -4.9 | 5.6 | 2.6e-08 | -0.97 | 0.00 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Soft Tissue Sarcoma | LCT | 0.09 | 0.04 | blup | 36 | 0.05 | 4.9e-04 | -5.6 | 5.6 | 2.4e-08 | -0.89 | 0.00 | 0.90 | FALSE |