Best TWAS P=7.62e-14 · Best GWAS P=1.2e-19 conditioned to 7.1e-09
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | PPARG | 0.57 | 0.57 | lasso | 5 | 0.54 | 3.6e-16 | -5.5 | -5.5 | 4.1e-08 | -0.11 | 1.00 | 0.00 | FALSE |
2 | GTEx | Brain Cerebellum | PPARG | 0.64 | 0.57 | lasso | 7 | 0.57 | 4.1e-20 | -5.5 | -5.9 | 3.4e-09 | -0.12 | 1.00 | 0.00 | TRUE |
3 | GTEx | Heart Left Ventricle | PPARG | 0.25 | 0.07 | enet | 36 | 0.10 | 5.1e-06 | 9.0 | 7.5 | 7.6e-14 | 0.69 | 0.01 | 0.98 | TRUE |