Best TWAS P=4.32e-09 · Best GWAS P=5.62e-07 conditioned to 0.0923
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SLC26A1 | 0.12 | 0.06 | bslmm | 400 | 0.08 | 8.0e-10 | 4.2 | 5.4 | 7.5e-08 | 0.42 | 0.07 | 0.80 | TRUE |
| 2 | GTEx | Artery Tibial | GAK | 0.19 | 0.03 | enet | 29 | 0.10 | 2.4e-08 | -2.8 | 5.3 | 9.6e-08 | 0.57 | 0.00 | 0.98 | FALSE |
| 3 | GTEx | Brain Cerebellum | SLC26A1 | 0.61 | 0.41 | enet | 22 | 0.46 | 2.1e-15 | 4.2 | 5.2 | 2.0e-07 | 0.57 | 0.06 | 0.83 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PCGF3 | 0.03 | 0.00 | blup | 69 | 0.01 | 3.7e-03 | 3.4 | 5.9 | 4.3e-09 | 0.44 | 0.00 | 0.04 | TRUE |