[Hub]/) : Traits : Trunk fat mass :

chr3:194,089,342-196,855,644

Best TWAS P=4.21e-09 · Best GWAS P=2.05e-08 conditioned to 0.00432

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue PCYT1A 0.11 0.03 lasso 3 0.00 3.9e-01 5.5 -5.5 4.8e-08 -0.08 0.01 0.88 FALSE
2 GTEx Breast Mammary Tissue SLC51A 0.28 0.06 lasso 6 0.14 1.3e-07 2.8 -5.2 2.3e-07 0.01 0.07 0.86 FALSE
3 GTEx Breast Mammary Tissue UBXN7 0.20 0.00 enet 16 0.02 3.5e-02 -4.9 -5.3 1.0e-07 0.02 0.03 0.87 FALSE
4 GTEx Pancreas XXYLT1 0.13 0.07 enet 13 0.07 8.7e-04 -4.3 5.3 1.1e-07 -0.41 0.20 0.35 FALSE
5 GTEx Spleen PCYT1A 0.19 0.05 lasso 4 0.09 3.1e-03 -4.1 -5.2 1.8e-07 -0.06 0.05 0.53 FALSE
6 GTEx Stomach SLC51A 0.13 0.06 enet 12 0.03 1.9e-02 4.7 -5.8 5.4e-09 -0.08 0.02 0.94 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma C3orf21 0.16 0.08 enet 18 0.16 1.7e-09 -5.2 5.7 1.6e-08 -0.67 0.03 0.97 TRUE
8 The Cancer Genome Atlas Brain Lower Grade Glioma UBXN7 0.02 0.01 blup 45 0.02 4.2e-03 4.1 -5.9 4.2e-09 -0.05 0.02 0.56 TRUE
9 The Cancer Genome Atlas Soft Tissue Sarcoma PCYT1A 0.12 0.05 blup 68 0.06 2.0e-04 4.8 -5.6 2.5e-08 -0.07 0.01 0.91 FALSE