Best TWAS P=1.15e-08 · Best GWAS P=3.91e-08 conditioned to 0.000806
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | HINT1 | 0.10 | 0.07 | enet | 16 | 0.06 | 8.8e-06 | -4.6 | -5.7 | 1.2e-08 | 0.43 | 0.1 | 0.86 | TRUE |
2 | GTEx | Artery Tibial | HINT1 | 0.11 | 0.04 | enet | 18 | 0.06 | 1.0e-05 | -4.2 | -5.6 | 2.6e-08 | 0.73 | 0.1 | 0.80 | FALSE |