TWAS
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Traits
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Traits
:
Trunk fat-free mass
:
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→
chr1:50,735,395-52,135,979
Best TWAS P=4.24e-17 · Best GWAS P=9.82e-21 conditioned to 3.53e-05
50.8M
51M
51.2M
51.4M
51.6M
51.8M
52M
52.2M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Gastroesophageal Junction
CDKN2C
0.14
0.11
enet
17
0.12
3e-05
9.1
-8.4
4.2e-17
-0.86
0.02
0.92
TRUE