[Hub]/) : Traits : Trunk fat-free mass : ← →

chr1:40,748,755-42,542,658

Best TWAS P=1.23e-44 · Best GWAS P=4.17e-34 conditioned to 0.00924

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	CTPS1	0.10	0.00	enet	8	0.00	4.6e-01	9.195	9.6	8.5e-22	0.75	0.05	0.59	FALSE
2	GTEx	Artery Coronary	CTPS1	0.25	-0.01	enet	23	0.00	3.0e-01	1.338	5.5	4.7e-08	0.39	0.07	0.13	FALSE
3	GTEx	Brain Cerebellum	FOXO6	0.35	0.33	enet	21	0.36	1.2e-11	4.154	6.6	3.2e-11	-0.01	0.98	0.01	FALSE
4	GTEx	Breast Mammary Tissue (Female)	CTPS1	0.12	-0.01	lasso	4	-0.01	7.5e-01	8.586	7.7	9.7e-15	0.61	0.04	0.10	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	CTPS1	0.26	0.11	lasso	6	0.08	1.6e-03	9.472	9.0	2.3e-19	0.70	0.19	0.35	FALSE
6	GTEx	Esophagus Muscularis	SCMH1	0.18	0.03	enet	19	0.10	1.1e-06	-1.603	-5.5	3.0e-08	-0.10	0.55	0.04	FALSE
7	GTEx	Lung	CTPS1	0.06	0.04	lasso	3	0.04	2.4e-04	9.733	10.3	7.1e-25	0.77	0.21	0.63	FALSE
8	GTEx	Nerve Tibial	SCMH1	0.16	0.03	enet	24	0.07	1.6e-05	11.884	-11.2	3.0e-29	-0.70	0.03	0.96	FALSE
9	GTEx	Testis	SLFNL1	0.30	0.17	lasso	14	0.28	5.3e-13	11.952	8.8	1.3e-18	0.85	0.01	0.99	FALSE
10	GTEx	Testis	CTPS1	0.57	0.28	enet	17	0.38	1.0e-17	-3.969	6.7	2.9e-11	0.48	0.97	0.03	FALSE
11	METSIM	Adipose	CTPS1	0.11	0.09	enet	31	0.09	6.2e-14	-3.969	5.7	1.0e-08	0.28	1.00	0.00	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	CTPS1	0.04	0.04	enet	7	0.04	9.1e-06	8.557	6.2	6.4e-10	0.59	0.60	0.16	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	SLFNL1	0.03	0.01	enet	6	0.02	5.6e-05	-1.603	6.7	2.1e-11	0.58	0.11	0.73	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	CTPS	0.05	0.04	blup	49	0.03	1.0e-04	-3.969	5.7	1.5e-08	0.33	0.13	0.09	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	SCMH1	0.04	0.01	enet	7	0.02	2.5e-03	-0.038	-8.4	6.3e-17	-0.70	0.01	0.82	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	CTPS	0.06	0.00	enet	14	0.02	3.3e-03	-0.938	-5.3	1.4e-07	-0.34	0.03	0.13	FALSE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	SCMH1	0.03	0.03	lasso	2	0.02	6.2e-03	12.170	-12.2	4.5e-34	-1.00	0.01	0.96	FALSE
18	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SCMH1	0.35	0.14	blup	96	0.14	1.5e-05	-5.674	7.0	3.2e-12	0.47	0.18	0.25	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	SCMH1	0.07	0.08	blup	97	0.07	2.5e-07	11.821	-14.0	1.2e-44	-0.75	0.11	0.89	TRUE