Best TWAS P=2.77e-09 · Best GWAS P=1.83e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | DAGLB | 0.09 | 0.06 | lasso | 5 | 0.06 | 4.8e-08 | 6.0 | -5.9 | 2.8e-09 | -0.98 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RAC1 | 0.03 | 0.02 | enet | 7 | 0.02 | 6.8e-05 | 4.6 | 5.6 | 1.7e-08 | 0.62 | 0.15 | 0.71 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | DAGLB | 0.06 | 0.02 | blup | 71 | 0.03 | 7.4e-04 | 4.8 | -5.4 | 7.4e-08 | -0.72 | 0.01 | 0.78 | FALSE |