[Hub]/) : Traits : Trunk fat-free mass :

chr7:1,704,673-3,581,391

Best TWAS P=1.64e-36 · Best GWAS P=1.47e-35 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AMZ1 0.19 0.12 enet 22 0.13 5.7e-16 6.1 7.7 1.0e-14 -0.43 1.00 0.00 TRUE
2 GTEx Adipose Subcutaneous GNA12 0.11 0.08 lasso 4 0.07 1.3e-06 -7.6 -8.4 3.6e-17 0.72 0.35 0.65 FALSE
3 GTEx Artery Tibial GNA12 0.24 0.13 enet 20 0.22 3.5e-17 -12.4 -10.6 2.0e-26 0.86 0.02 0.98 FALSE
4 GTEx Breast Mammary Tissue (Male) EIF3B 0.38 -0.01 enet 28 0.12 1.3e-03 6.5 -5.2 2.4e-07 0.06 0.04 0.06 TRUE
5 GTEx Cells EBV-transformed lymphocytes GNA12 0.46 0.51 lasso 5 0.50 7.9e-19 -12.3 -12.3 1.1e-34 0.90 0.02 0.98 FALSE
6 GTEx Cells Transformed fibroblasts GNA12 0.21 0.11 lasso 11 0.15 1.7e-11 -12.4 -9.9 2.5e-23 0.87 0.01 0.99 FALSE
7 GTEx Colon Sigmoid GNA12 0.14 0.05 lasso 3 0.03 3.6e-02 -7.6 -10.2 2.0e-24 0.82 0.04 0.88 FALSE
8 GTEx Colon Transverse GNA12 0.19 0.08 lasso 4 0.10 2.3e-05 6.5 -7.3 2.0e-13 0.62 0.21 0.77 FALSE
9 GTEx Esophagus Gastroesophageal Junction GNA12 0.20 0.12 lasso 6 0.12 3.4e-05 -7.6 -10.2 1.5e-24 0.82 0.05 0.93 FALSE
10 GTEx Esophagus Mucosa GNA12 0.16 0.13 lasso 3 0.13 3.0e-09 -12.3 -11.3 1.3e-29 0.93 0.01 0.99 FALSE
11 GTEx Esophagus Muscularis GNA12 0.32 0.31 lasso 3 0.34 2.1e-21 -12.4 -11.9 7.9e-33 0.93 0.01 0.99 TRUE
12 GTEx Lung GNA12 0.16 0.08 enet 21 0.12 1.2e-09 -12.3 -9.9 5.5e-23 0.78 0.01 0.99 FALSE
13 GTEx Nerve Tibial GNA12 0.31 0.34 lasso 7 0.36 9.6e-27 -7.7 -10.1 9.1e-24 0.83 0.89 0.11 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic GNA12 0.10 0.15 lasso 3 0.12 4.2e-07 6.0 -6.6 4.3e-11 0.55 0.36 0.62 FALSE
15 GTEx Skin Sun Exposed Lower leg GNA12 0.17 0.16 lasso 3 0.18 1.3e-14 -7.4 -10.0 2.2e-23 0.85 0.16 0.84 FALSE
16 GTEx Skin Sun Exposed Lower leg AC004840.9 0.18 0.01 enet 36 0.02 3.7e-03 2.6 -5.4 6.8e-08 0.15 0.18 0.21 TRUE
17 GTEx Small Intestine Terminal Ileum GNA12 0.34 0.20 lasso 5 0.16 2.4e-04 -7.6 -8.3 9.5e-17 0.74 0.08 0.74 TRUE
18 GTEx Stomach GNA12 0.18 0.16 lasso 2 0.13 6.6e-07 -7.6 -7.7 1.7e-14 0.68 0.54 0.44 FALSE
19 GTEx Whole Blood GNA12 0.09 0.01 enet 4 0.00 3.3e-01 -12.0 -12.1 1.7e-33 0.90 0.02 0.90 FALSE
20 METSIM Adipose GNA12 0.07 0.05 lasso 3 0.05 3.3e-08 -7.6 -7.7 1.1e-14 0.75 0.37 0.63 FALSE
21 NTR Blood GNA12 0.07 0.03 bslmm 597 0.06 1.3e-17 -9.2 -8.9 4.3e-19 0.58 0.94 0.06 FALSE
22 ROSMAP Brain Pre-frontal Cortex AMZ1 0.09 0.05 lasso 6 0.04 2.4e-06 -12.4 12.6 1.6e-36 -0.89 0.01 0.99 TRUE
23 YFS Blood GNA12 0.23 0.15 bslmm 570 0.25 4.5e-82 5.9 -8.0 1.3e-15 0.47 1.00 0.00 TRUE
24 The Cancer Genome Atlas Esophageal Carcinoma AMZ1 0.18 0.05 blup 69 0.05 1.4e-02 7.6 -10.3 7.3e-25 0.75 0.01 0.67 FALSE
25 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GNA12 0.03 0.04 lasso 1 0.04 3.0e-05 -7.6 -7.6 3.8e-14 0.68 0.07 0.79 FALSE
26 The Cancer Genome Atlas Brain Lower Grade Glioma AMZ1 0.04 0.04 lasso 3 0.02 1.3e-03 7.6 8.8 1.1e-18 -0.67 0.03 0.93 FALSE
27 The Cancer Genome Atlas Lung Adenocarcinoma GNA12 0.03 0.01 enet 7 0.02 1.5e-03 4.8 -9.8 6.7e-23 0.76 0.06 0.74 FALSE
28 The Cancer Genome Atlas Prostate Adenocarcinoma AMZ1 0.08 0.01 blup 71 0.05 1.3e-05 -7.6 5.2 1.8e-07 -0.66 0.03 0.84 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma AMZ1 0.32 0.04 enet 19 0.20 3.3e-19 -9.2 5.6 2.6e-08 -0.57 0.15 0.85 TRUE