[Hub]/) : Traits : Trunk fat-free mass : ← →

chr9:138,403,706-140,321,666

Best TWAS P=3e-13 · Best GWAS P=2.03e-10 conditioned to 0.012

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Brain Caudate basal ganglia	SNHG7	0.37	0.10	lasso	6	0.27	2.5e-08	-3.8	7.3	3.0e-13	0.39	0.10	0.46	TRUE
14	GTEx	Ovary	SEC16A	0.33	0.06	enet	10	0.14	3.4e-04	4.8	-6.6	4.8e-11	-0.45	0.06	0.09	TRUE
13	GTEx	Ovary	INPP5E	0.24	0.13	enet	11	0.15	1.9e-04	5.2	-6.5	6.1e-11	-0.59	0.09	0.48	FALSE
32	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	INPP5E	0.07	0.04	blup	54	0.07	6.0e-05	6.4	-6.4	1.4e-10	-0.84	0.01	0.97	FALSE
23	GTEx	Whole Blood	SEC16A	0.07	0.05	lasso	5	0.04	1.3e-04	5.6	-6.2	5.0e-10	-0.72	0.06	0.94	FALSE
30	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	INPP5E	0.25	0.10	lasso	3	0.09	4.9e-05	6.0	-6.2	6.0e-10	-0.73	0.03	0.92	FALSE
34	The Cancer Genome Atlas	Prostate Adenocarcinoma	SEC16A	0.08	0.10	lasso	4	0.08	1.9e-08	6.3	-6.1	1.0e-09	-0.98	0.00	1.00	FALSE
31	The Cancer Genome Atlas	Colon Adenocarcinoma	INPP5E	0.11	0.08	lasso	2	0.08	3.4e-05	6.0	-6.0	2.3e-09	-0.72	0.02	0.87	FALSE
35	The Cancer Genome Atlas	Testicular Germ Cell Tumors	INPP5E	0.10	0.06	blup	54	0.08	8.1e-04	5.4	-5.9	2.8e-09	-0.82	0.05	0.59	FALSE
28	YFS	Blood	INPP5E	0.33	0.55	lasso	6	0.57	2.9e-235	6.0	-5.9	3.2e-09	-0.70	0.06	0.94	FALSE
1	CommonMind	Brain Pre-frontal Cortex	INPP5E	0.18	0.14	enet	21	0.21	1.6e-24	6.1	-5.8	6.9e-09	-0.89	0.01	0.99	FALSE
5	GTEx	Brain Cerebellar Hemisphere	INPP5E	0.25	0.23	enet	6	0.17	3.4e-05	5.4	-5.8	7.4e-09	-0.68	0.20	0.70	FALSE
12	GTEx	Nerve Tibial	INPP5E	0.13	0.17	enet	10	0.14	3.7e-10	5.5	-5.7	9.9e-09	-0.64	0.39	0.61	FALSE
22	GTEx	Uterus	INPP5E	0.60	0.04	enet	10	0.22	3.4e-05	6.0	-5.7	1.1e-08	-0.53	0.07	0.36	FALSE
18	GTEx	Stomach	SEC16A	0.15	0.09	lasso	4	0.10	1.8e-05	5.8	-5.7	1.6e-08	-0.69	0.11	0.87	FALSE
10	GTEx	Heart Atrial Appendage	INPP5E	0.13	0.12	lasso	2	0.10	3.5e-05	5.6	-5.6	1.9e-08	-0.71	0.12	0.64	FALSE
33	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SDCCAG3	0.05	0.01	blup	61	0.01	5.9e-02	6.1	-5.6	1.9e-08	-0.81	0.01	0.88	FALSE
6	GTEx	Brain Cerebellum	INPP5E	0.40	0.30	enet	20	0.29	3.6e-09	5.6	-5.6	2.1e-08	-0.63	0.29	0.71	FALSE
3	GTEx	Brain Caudate basal ganglia	INPP5E	0.23	0.20	enet	8	0.22	7.2e-07	5.6	-5.6	2.7e-08	-0.62	0.19	0.69	FALSE
9	GTEx	Esophagus Muscularis	SDCCAG3	0.10	0.02	enet	5	0.02	3.6e-02	3.4	-5.5	2.8e-08	-0.59	0.04	0.86	FALSE
8	GTEx	Esophagus Mucosa	INPP5E	0.11	0.12	lasso	3	0.12	1.0e-08	5.4	-5.5	4.0e-08	-0.67	0.31	0.69	FALSE
36	The Cancer Genome Atlas	Thyroid Carcinoma	INPP5E	0.11	0.16	lasso	3	0.16	2.4e-15	5.2	-5.5	4.0e-08	-0.70	0.71	0.29	FALSE
20	GTEx	Testis	SDCCAG3	0.15	0.09	lasso	4	0.13	3.3e-06	4.3	-5.5	4.7e-08	-0.84	0.07	0.90	FALSE
24	GTEx	Whole Blood	SDCCAG3	0.07	0.03	enet	6	0.02	3.4e-03	5.0	-5.4	5.9e-08	-0.79	0.14	0.80	FALSE
21	GTEx	Thyroid	INPP5E	0.23	0.35	enet	16	0.37	8.2e-30	4.7	-5.4	6.0e-08	-0.74	0.84	0.16	FALSE
25	GTEx	Whole Blood	CARD9	0.08	0.07	lasso	1	0.05	4.2e-05	5.4	5.4	6.4e-08	0.55	0.42	0.57	FALSE
7	GTEx	Cells Transformed fibroblasts	CARD9	0.10	0.01	enet	15	0.02	8.0e-03	-1.1	-5.3	9.0e-08	-0.47	0.17	0.54	FALSE
11	GTEx	Lung	CARD9	0.08	0.04	enet	6	0.04	2.5e-04	5.3	5.3	9.7e-08	0.59	0.58	0.35	FALSE
2	GTEx	Adrenal Gland	INPP5E	0.18	0.02	enet	23	0.10	2.2e-04	4.7	-5.3	1.1e-07	-0.56	0.14	0.42	FALSE
29	The Cancer Genome Atlas	Breast Invasive Carcinoma	SEC16A	0.02	0.00	blup	69	0.01	1.0e-03	5.6	-5.3	1.1e-07	-0.75	0.02	0.89	FALSE
27	YFS	Blood	CARD9	0.22	0.37	lasso	5	0.39	1.3e-137	5.4	5.3	1.2e-07	0.64	0.48	0.52	FALSE
17	GTEx	Skin Sun Exposed Lower leg	INPP5E	0.10	0.10	lasso	2	0.09	5.2e-08	5.4	-5.3	1.4e-07	-0.66	0.29	0.71	FALSE
15	GTEx	Pancreas	SEC16A	0.28	0.10	enet	16	0.16	4.1e-07	5.6	-5.2	2.6e-07	-0.67	0.10	0.90	FALSE
16	GTEx	Pituitary	INPP5E	0.21	0.24	lasso	3	0.14	1.8e-04	5.6	5.2	2.6e-07	0.68	0.13	0.54	FALSE
19	GTEx	Testis	INPP5E	0.24	0.32	enet	10	0.30	5.4e-14	5.5	-5.1	3.0e-07	-0.68	0.24	0.76	FALSE
26	METSIM	Adipose	QSOX2	0.06	0.00	bslmm	370	0.02	1.8e-03	3.4	5.1	3.0e-07	0.35	0.07	0.52	FALSE