Best TWAS P=2.5e-09 · Best GWAS P=2.34e-09 conditioned to 0.000936
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | WAC | 0.10 | 0.00 | enet | 32 | 0.00 | 0.56500 | -5.6 | -6.0 | 2.5e-09 | 0.53 | 0.04 | 0.56 | TRUE |
2 | GTEx | Vagina | WAC-AS1 | 0.55 | 0.25 | lasso | 5 | 0.22 | 0.00001 | 4.6 | 5.3 | 1.0e-07 | -0.43 | 0.57 | 0.08 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | WAC | 0.06 | 0.04 | lasso | 3 | 0.03 | 0.00042 | 4.7 | 5.2 | 1.8e-07 | -0.42 | 0.22 | 0.10 | FALSE |