Hub : Genes

WAC

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1028	0.0390	5.4e-03	-0.004	NA	-0.002	NA	-0.003	9.6e-01	NA	5.6e-01	NA	9.0e-01
2	GTEx	Brain Cerebellum	0.3300	0.1050	2.9e-03	-0.010	NA	0.005	NA	0.013	9.3e-01	NA	2.2e-01	NA	1.3e-01
3	GTEx	Testis	0.2290	0.0780	1.3e-03	0.049	NA	0.085	NA	0.075	3.1e-03	NA	1.3e-04	NA	3.2e-04
4	ROSMAP	Brain Pre-frontal Cortex	0.2120	0.0319	0.0e+00	0.288	0.233	0.284	0.282	0.286	2.7e-37	1.4e-29	9.1e-37	2.3e-36	5.9e-37
5	YFS	Blood	0.0616	0.0128	2.2e-16	0.077	0.063	0.076	0.078	0.075	4.8e-24	1.0e-19	8.3e-24	2.2e-24	1.6e-23
6	TCGA	Pheochromocytoma and Paraganglioma	0.1090	0.0700	2.0e-03	0.040	0.067	0.045	NA	0.047	1.0e-02	1.3e-03	6.8e-03	NA	5.7e-03
7	TCGA	Prostate Adenocarcinoma	0.0657	0.0305	9.3e-06	0.025	0.059	0.053	NA	0.047	1.1e-03	8.7e-07	3.2e-06	NA	1.0e-05
8	TCGA	Thyroid Carcinoma	0.0580	0.0390	1.2e-03	0.045	0.026	0.022	NA	0.032	3.1e-05	1.2e-03	3.1e-03	NA	4.2e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	3.4	5.4	8.1	-0.9	2.8	-0.7	2.5	-2.5	2.8	2.7	2.4
Bipolar Disorder or Schizophrenia	5.0	12.2	22.7	-1.9	3.2	-0.2	3.8	-3.5	4.4	4.8	3.9
Depressed Affect (Nagel 2018)	0.3	0.7	2.3	-0.6	1.5	-1.2	0.5	-0.6	0.6	0.6	0.3
Depression (Nagel 2018)	2.9	4.3	6.0	-1.5	2.0	-1.1	2.4	-2.4	2.2	2.1	2.4
Intelligence (Savage-Jansen 2018)	1.6	4.9	11.4	-1.1	0.3	-1.7	3.1	-3.4	2.2	1.1	2.9
Neuroticism (Nagel 2018)	0.5	1.1	1.9	-0.8	1.2	-1.4	0.9	-0.7	1.0	1.3	0.9
Schizophrenia (2018)	3.3	7.0	15.3	-1.4	1.8	0.3	2.8	-2.5	3.4	3.9	3.1
Schizophrenia vs Biploar Disorder	0.3	0.4	1.7	0.2	1.3	0.7	0.1	0.1	0.5	0.8	0.2
Worry (Nagel 2018)	0.8	1.8	2.9	-0.6	0.8	-0.6	1.7	-1.4	1.7	1.7	1.5
Alzheimer’s Disease (in mother)	5.2	6.1	9.1	2.9	-1.4	0.9	-3.0	2.9	-2.7	-2.2	-2.9
Alzheimer’s Disease (in father)	0.2	0.3	0.5	-0.6	-0.1	0.6	0.7	-0.7	0.4	-0.0	0.3
Alzheimer’s Disease (including proxy)	5.0	7.3	11.0	2.2	-1.6	1.5	-3.1	3.2	-3.2	-2.7	-3.3
Crohns Disease (2017)	0.3	0.6	1.2	-0.2	-0.9	-0.7	-0.4	0.6	-1.1	-1.1	-0.4
Irritable Bowel Disease (IBD)	0.3	0.8	1.6	-0.5	-0.9	-0.0	-0.8	1.1	-1.3	-1.2	-0.6
Ulcerative Colitis (UC)	0.2	0.3	0.6	-0.2	-0.2	0.8	-0.6	0.8	-0.6	-0.5	-0.4
Major Depression (MDD)	0.1	0.2	0.4	-0.5	0.6	-0.2	0.5	-0.5	0.4	-0.1	0.2
Reaction Time	0.4	0.7	1.3	-1.1	0.0	-0.6	-0.7	1.0	-1.1	-0.9	-0.7
Verbal and Numeric Reasoning (VNR)	0.9	2.2	5.0	-0.5	1.4	-0.9	2.1	-2.2	1.3	0.5	1.8
Breast Cancer	0.2	0.5	1.4	-0.2	-1.2	0.8	-0.8	0.7	-0.3	-0.1	-0.7
Ovarian Cancer	0.1	0.1	0.4	-0.6	0.4	0.3	0.4	-0.3	0.4	0.1	0.4
Prostate Cancer	0.6	0.9	1.3	0.7	-1.1	0.5	-0.9	0.9	-1.2	-1.0	-1.1
Age at First Birth	1.5	2.1	8.4	1.0	-2.9	-0.6	-1.2	1.3	-1.5	-1.1	-0.8
Bipolar Disorder (2011)	2.8	2.7	5.4	0.1	1.8	1.0	1.8	-1.8	2.3	2.0	1.4
Body Mass Index (BMI) (2010)	0.2	0.3	0.8	-0.9	-0.2	-0.4	0.5	-0.6	0.7	0.5	0.4
Coronary Artery Disease (CAD)	0.2	0.2	0.5	0.7	0.4	-0.1	-0.4	-0.0	-0.2	-0.6	-0.6
Crohns Disease (2012)	0.1	0.2	1.1	-0.5	1.0	-0.3	-0.0	-0.1	-0.1	-0.2	-0.1
Mean Putamen Volume	0.2	0.2	0.6	-0.6	0.7	-0.2	-0.5	0.4	-0.4	-0.1	-0.4
Fasting Glucose	0.2	0.3	0.5	-0.4	-0.2	-0.2	0.6	-0.7	0.6	0.5	0.7
HbA1C	1.2	1.3	2.9	-1.7	-1.2	0.3	-1.0	1.0	-1.1	-1.3	-1.0
HDL Cholesterol	2.4	4.0	10.9	3.3	2.1	3.1	0.7	-1.0	1.8	1.6	0.3
LDL Cholesterol	0.2	0.3	1.1	-0.0	-1.1	-0.6	0.4	-0.4	-0.1	-0.5	0.4
Lupus	0.6	0.9	1.5	1.0	-1.2	-1.0	-0.8	0.8	-0.9	-0.7	-0.7
Neuroticism (2016)	0.5	0.7	1.7	0.6	1.1	-0.5	0.7	-0.5	0.8	1.3	0.7
Primary Biliary Cirrhosis	1.2	1.7	3.2	1.1	1.8	0.5	1.2	-1.3	1.7	1.6	0.8
Rheumatoid Arthritis	0.6	0.8	1.8	-1.0	0.1	-0.1	1.0	-1.4	1.2	0.8	0.9
Schizophrenia (2014)	4.1	9.0	19.0	-1.1	2.1	0.4	3.2	-3.0	3.9	4.4	3.6
Triglycerides	1.1	1.8	5.5	-1.4	-2.3	-2.3	0.5	-0.3	-0.4	-0.6	0.9
Type 2 Diabetes (T2D) (2012)	0.4	0.4	0.8	0.9	0.1	0.5	0.4	-0.7	0.7	0.7	0.8
Ulcerative Colitis	0.1	0.1	0.3	-0.0	-0.2	0.4	-0.3	0.5	-0.2	0.3	-0.0
Blood Eosinophil Count	14.2	109.2	201.6	5.2	-4.0	4.8	-13.9	14.2	-12.2	-9.4	-13.3
Blood Platelet Count	0.3	3.6	7.3	-0.1	-1.9	0.5	-2.7	2.5	-2.3	-1.1	-2.1
Blood Red Count	0.1	0.5	1.8	-1.4	0.5	-1.1	0.6	-0.5	0.2	-0.4	0.3
Blood White Count	11.1	82.5	144.0	4.1	-4.2	5.7	-11.8	12.0	-10.4	-8.2	-11.6
Heel T-Score	1.2	9.7	52.1	-7.2	-0.2	-1.9	-1.2	1.1	-2.0	-3.4	-1.9
BMI	0.1	0.3	1.8	-1.4	0.4	-0.2	-0.4	0.2	-0.2	-0.6	-0.4
Height	3.9	74.9	141.6	-5.3	0.5	-6.5	11.4	-10.9	8.8	7.8	11.9
Waist Hip Ratio (WHR)	0.5	2.0	4.4	-0.9	-1.9	-1.2	-0.7	1.1	-1.8	-2.1	-0.9
Systolic Blood Pressure	0.5	2.4	8.0	2.4	0.5	2.8	-1.3	1.3	-0.0	0.6	-1.3
Smoking Status	0.4	0.9	3.4	-1.8	0.8	-1.0	0.9	-0.9	0.4	-0.1	0.6
Allergy or Eczema	0.2	0.4	2.0	1.4	0.0	1.2	0.1	-0.0	0.1	0.2	-0.0
Cardiovascular Disease	0.9	3.0	8.4	1.1	2.5	2.9	0.8	-0.9	2.0	1.7	0.4
Hypothyroidism (self reported)	0.5	1.2	1.8	-0.8	-1.2	0.2	-1.2	1.2	-1.4	-1.1	-1.2
Respiratory disease	0.3	0.7	1.5	1.1	-0.3	1.2	-1.1	1.1	-0.4	0.1	-0.9
Type 2 Diabetes (T2D) (2018)	0.6	1.2	3.6	-0.5	-1.3	-1.9	-0.2	0.3	-1.0	-1.7	0.0
Lung FEV1/FVC ratio	1.0	5.2	8.8	-2.0	2.2	0.0	3.0	-2.9	2.9	1.3	2.3
Lung FVC	1.3	6.4	11.3	-0.6	3.4	-1.4	3.0	-2.9	2.9	2.2	2.6
Neuroticism	0.2	0.6	2.3	-0.3	1.5	-0.9	0.3	-0.1	0.6	1.1	0.2
Chronotype (morning person)	1.8	4.2	8.6	-0.3	-1.6	-1.2	2.8	-2.9	2.0	1.4	2.7
Hair Pigment	0.2	6.2	16.2	0.7	0.3	4.0	-3.1	2.8	-1.9	-1.0	-3.2
Tanning	0.4	4.9	17.5	-2.6	0.1	-4.2	2.2	-1.9	0.4	-0.2	2.5
Hand grip strength (left)	2.2	5.9	11.4	-2.0	-0.4	-3.1	2.9	-2.8	1.7	1.7	3.4
Number of treatments/medications taken	0.8	1.4	2.7	1.6	1.4	1.3	0.6	-0.7	1.5	1.2	0.3
Average weekly spirits intake	1.7	2.1	5.0	-0.1	0.2	-2.2	-1.2	1.3	-2.0	-2.0	-0.9
Sensitivity / hurt feelings	2.0	3.4	7.5	1.8	-0.1	-0.2	-2.5	2.7	-2.3	-1.0	-2.0
Frequency of depressed mood in last 2 weeks	2.3	3.2	4.0	-1.4	1.8	-1.6	1.9	-1.7	1.8	1.9	2.0
Hearing difficulty/problems: Yes	1.6	2.4	7.8	-1.8	-0.9	-2.8	1.6	-1.6	0.2	-0.8	1.3
Relative age of first facial hair	1.6	3.3	7.7	0.2	0.5	0.6	-2.8	2.8	-2.3	-1.1	-1.9
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	2.0	0.1	-0.6	-1.1	1.3	-1.1	1.1	1.4	1.4
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.3	0.4	0.5	1.1	-1.1	1.0	-0.3	0.1	-1.1
Ever had hysterectomy (womb removed)	0.6	0.6	1.2	-0.4	0.6	0.7	-1.0	0.9	-0.6	-0.7	-1.1
Systolic blood pressure, automated reading	0.5	1.5	6.5	1.5	0.4	2.5	-0.9	0.9	0.0	0.2	-1.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.5	0.5	0.6	0.6	-0.1	0.2	0.1	0.7	0.1
Angina	0.6	0.8	1.8	-0.3	-1.1	0.1	-0.8	1.0	-1.0	-1.3	-0.9
Medication for hormone replacement therapy	1.1	1.2	6.0	-2.4	0.5	0.5	0.7	-0.6	0.9	0.9	0.7
Vitamin and mineral supplements	0.4	0.5	0.9	-0.3	0.5	0.5	0.7	-1.0	1.0	0.9	0.7
Supplements: Zinc	0.5	0.5	1.0	-0.4	0.1	0.1	-1.0	1.0	-0.9	-0.4	-0.8
Medication: Co-codamol	0.5	0.5	2.5	1.6	0.5	0.3	0.7	-0.5	0.5	0.4	0.4
Medication: Metformin	0.6	0.9	2.1	-0.9	-0.6	-1.5	-0.6	0.9	-1.1	-1.2	-0.3
Diabetes (father)	1.5	1.9	4.4	0.0	0.3	-0.9	-1.4	1.4	-2.0	-2.1	-1.4
Diabetes (mother)	0.6	0.8	3.2	0.1	0.5	1.8	-0.7	1.1	-0.1	-0.3	-1.0
Severe depression (siblings)	1.9	2.2	5.3	-0.8	-0.5	-1.8	2.1	-2.3	1.1	0.1	1.5
Pack years adult smoking proportion	0.7	1.0	2.7	1.4	-1.6	-0.6	-0.8	0.8	-1.0	-0.8	-0.7
Impedance of leg (right)	0.5	2.5	10.0	3.2	-0.1	1.9	-1.3	1.5	-0.5	0.3	-1.4
Leg fat-free mass (left)	2.3	12.4	19.6	-4.4	0.2	-3.4	4.2	-4.1	2.9	2.3	4.4
Trunk fat percentage	0.3	1.0	3.2	0.6	1.7	1.8	0.1	-0.1	0.8	0.9	-0.3
Hand grip strength (right)	1.4	3.7	7.0	-1.7	-1.5	-2.7	2.3	-2.1	0.9	0.5	2.5
Townsend deprivation index at recruitment	0.2	0.3	0.5	-0.4	0.7	0.5	0.5	-0.5	0.7	0.7	0.3
Current tobacco smoking	0.4	0.6	2.4	-1.6	0.6	-1.2	0.3	-0.1	-0.5	-0.6	0.1
Average weekly fortified wine intake	2.3	2.7	6.2	0.3	0.8	1.2	-2.3	2.5	-1.7	-1.1	-2.1
Maternal smoking around birth	0.3	0.4	1.9	-0.4	-1.4	-0.6	-0.2	0.1	-0.4	-0.5	-0.2
Fed-up feelings	0.7	1.3	4.6	-0.7	2.1	-0.9	0.8	-0.7	1.1	1.2	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	2.6	3.5	5.2	-2.1	1.1	-1.9	2.3	-2.0	1.7	1.7	2.1
Relative age voice broke	0.4	0.6	1.4	-0.5	-0.6	-0.8	-0.7	1.1	-1.2	-0.6	-0.1
Taking other prescription medications	0.2	0.4	1.8	0.2	-0.2	1.4	-0.3	0.2	0.5	0.7	-0.3
Age when periods started (menarche)	0.8	2.0	3.9	0.3	-1.5	-0.9	-1.7	1.6	-2.0	-1.4	-1.1
Bilateral oophorectomy (both ovaries removed)	1.7	1.9	3.7	0.6	-0.5	0.3	-1.8	1.9	-1.7	-1.4	-1.7
Heel bone mineral density (BMD) T-score, automated (left)	1.3	2.9	9.8	-3.1	-1.0	-2.2	1.6	-1.5	0.3	-0.9	1.1
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	3.2	-0.3	0.4	1.0	0.3	-0.3	1.3	1.8	0.4
Qualifications: CSEs or equivalent	0.4	0.5	1.2	0.2	1.1	-0.8	0.8	-0.7	0.5	0.4	0.7
Serious illness, injury or assault to yourself	3.6	4.4	8.2	1.3	1.8	0.6	2.0	-2.5	2.9	2.7	2.1
High blood pressure	1.1	3.0	6.8	1.4	2.6	2.2	0.7	-0.9	2.1	2.0	0.6
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.7	1.3	-0.2	0.7	0.2	-0.1	-0.0	-0.0	0.0
Multivitamins +/- minerals	0.6	0.8	1.4	0.9	0.0	1.2	-1.0	1.1	-0.6	-0.6	-1.0
Stomach or abdominal pain in last month	0.5	0.7	3.8	1.2	1.9	0.2	-0.2	0.2	0.2	0.0	-0.4
Supplements: Glucosamine	0.2	0.3	1.2	-0.4	0.1	0.0	-0.1	0.1	0.9	1.1	-0.0
Diverticular disease/diverticulitis (self-reported)	2.7	3.2	6.5	2.5	-0.3	2.3	-2.0	2.0	-1.3	-0.8	-1.9
Medication: Atenolol	1.5	1.9	3.8	0.8	-0.9	-1.0	-1.6	1.4	-1.6	-1.9	-1.5
Medication: Levothyroxine sodium	0.4	0.7	2.0	-1.4	-0.1	0.1	-0.9	1.0	-0.9	-0.7	-0.8
Sitting height	3.7	26.2	45.4	-5.8	0.6	-4.5	6.7	-6.2	4.6	2.9	6.5
Chronic bronchitis/emphysema (father)	0.3	0.3	2.1	-1.5	-0.3	-0.2	-0.4	0.4	-0.3	0.2	-0.1
High blood pressure (mother)	0.8	1.1	2.7	0.1	0.6	1.1	1.0	-0.8	1.7	1.5	0.7
Body mass index (BMI)	0.1	0.5	0.9	-0.7	0.6	0.2	-0.9	0.8	-0.7	-0.8	-0.9
Impedance of leg (left)	0.6	2.9	10.4	3.2	0.2	2.4	-1.4	1.6	-0.5	0.1	-1.6
Leg predicted mass (left)	2.4	12.7	20.2	-4.4	0.2	-3.4	4.3	-4.2	3.0	2.4	4.5
Trunk fat mass	0.3	1.4	2.1	-1.0	1.4	0.2	1.4	-1.3	1.4	1.2	1.1
Waist circumference	0.0	0.1	0.9	-0.9	0.4	-0.0	0.2	-0.1	0.1	-0.1	0.1
Number of incorrect matches in round	0.7	1.1	2.6	-0.5	-0.8	0.2	-1.6	1.4	-1.2	-0.6	-1.2
Past tobacco smoking	1.3	2.3	3.6	1.9	-0.2	1.8	-1.8	1.8	-1.4	-0.8	-1.6
Alcohol usually taken with meals	1.6	2.6	4.7	-0.3	1.5	-0.4	1.7	-1.7	1.9	2.2	2.1
Nervous feelings	0.2	0.3	0.7	-0.7	0.1	-0.9	0.6	-0.3	0.5	0.5	0.6
Frequency of tenseness / restlessness in last 2 weeks	2.4	3.8	7.0	-1.8	0.2	-2.6	2.2	-1.9	1.6	1.9	2.3
Hearing difficulty/problems with background noise	1.2	2.0	3.6	-0.7	0.4	-0.9	1.8	-1.9	1.6	1.2	1.8
Hair/balding pattern: Pattern 2	0.3	0.4	1.0	-0.8	0.5	-0.8	0.1	-0.3	0.2	1.0	0.6
Had menopause	0.9	1.1	4.0	-0.4	2.0	1.1	-0.1	-0.3	1.1	1.5	0.2
Had other major operations	0.4	0.5	2.0	-0.2	-0.6	0.1	-0.5	0.5	-0.8	-1.4	-0.8
Forced vital capacity (FVC)	4.3	16.6	28.3	-3.2	1.8	-3.8	5.2	-4.8	3.9	3.4	5.3
Heel bone mineral density (BMD) T-score, automated (right)	2.0	4.6	18.7	-4.3	-0.8	-3.0	1.7	-1.6	0.2	-1.1	1.1
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.7	-0.1	1.0	-1.6	0.5	-0.4	-0.1	0.4	0.6
Qualifications: None of the above	0.5	1.1	3.8	0.3	1.9	1.6	-1.0	0.5	-0.1	-0.1	-1.2
Financial difficulties in last 2 years	0.3	0.4	1.9	-0.1	-1.4	-0.4	-0.5	0.8	-0.5	-0.0	-0.5
Mouth/teeth dental problems	1.8	2.8	5.1	1.1	-2.0	-1.0	-1.4	1.5	-2.0	-2.3	-1.6
Heart attack	0.7	0.9	1.7	-0.6	0.1	-1.3	-1.1	1.0	-1.2	-1.0	-1.0
Allergy	0.5	1.1	4.0	-2.0	-0.7	-1.9	0.1	-0.1	-0.4	-0.5	0.3
Pain all over the body in last month	2.3	2.4	6.8	-0.9	-1.3	-1.9	-1.0	1.0	-1.8	-2.6	-1.2
Diabetes (self-reported)	0.8	1.3	5.1	-1.1	-0.8	-2.3	-0.3	0.6	-1.1	-1.2	0.1
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	3.4	1.8	-1.1	0.9	-1.0	0.9	-0.9	-0.4	-0.6
Medication: Ramipril	1.0	1.3	5.6	-2.4	-0.1	-2.1	0.2	-0.5	-0.1	0.1	0.6
Medication: Simvastatin	0.4	0.5	1.3	0.9	1.1	-0.1	0.7	-0.8	0.8	0.4	0.4
Fluid intelligence score	1.0	2.1	4.7	-1.5	-0.9	-2.2	1.8	-1.7	0.5	-0.3	1.6
Illnesses of siblings	1.5	2.0	2.7	-1.6	-1.2	-1.6	1.3	-1.4	1.0	1.5	1.6
Neuroticism score	0.4	0.9	3.7	-0.2	1.4	-1.9	0.4	-0.1	0.4	1.0	0.6
Weight	1.0	4.9	9.6	-3.1	0.8	-1.8	2.5	-2.5	1.9	1.5	2.6
Impedance of arm (right)	1.0	4.8	12.4	3.0	1.7	3.5	0.1	-0.1	1.9	3.2	0.2
Arm fat percentage (right)	0.2	0.9	3.7	0.6	1.4	1.9	-0.5	0.3	0.3	0.5	-0.7
Trunk fat-free mass	3.1	17.7	35.5	-6.0	-0.2	-4.8	4.8	-4.6	2.7	1.9	5.2
Hip circumference	0.5	2.0	3.2	-1.4	1.7	0.2	1.3	-1.3	1.6	1.8	1.4
Time employed in main current job	0.1	0.2	0.3	0.2	-0.2	-0.5	-0.5	0.5	-0.4	-0.4	-0.3
Alcohol intake versus 10 years previously	0.2	0.3	1.2	-0.4	-0.7	0.2	-0.0	0.2	-0.5	-1.1	-0.3
Father’s age at death	0.3	0.4	1.3	-1.2	-0.5	-0.8	0.4	-0.6	-0.1	-0.3	0.7
Worrier / anxious feelings	0.7	1.3	3.5	-0.1	0.5	-1.0	1.2	-1.0	1.3	1.9	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	3.1	-0.9	1.8	-0.4	1.0	-0.6	1.3	1.6	1.0
Falls in the last year	0.9	1.2	3.5	0.3	0.9	0.6	0.9	-0.9	1.4	1.9	1.2
Hair/balding pattern: Pattern 3	0.4	0.6	2.1	1.5	-0.3	0.3	-0.3	0.3	-0.7	-1.1	-0.8
Number of live births	1.2	1.7	3.1	0.3	0.3	1.2	1.4	-1.7	1.8	1.5	1.2
Forced expiratory volume in 1-second (FEV1)	5.2	17.6	29.9	-3.2	1.9	-3.6	5.5	-5.1	4.3	3.3	5.4
Pulse rate	0.9	1.5	2.7	-1.0	1.1	0.9	1.2	-1.3	1.6	1.4	1.0
Happiness	0.7	0.9	2.9	-0.6	1.7	0.5	0.4	-0.4	0.9	1.4	0.3
Noisy workplace	0.8	1.0	2.0	-0.8	0.7	1.0	-1.3	1.1	-0.8	-0.6	-1.4
Qualifications: A levels/AS levels or equivalent	2.5	5.5	10.5	0.2	1.3	-1.0	2.8	-3.0	2.6	2.6	3.2
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	0.8	0.7	-0.5	-0.4	0.9	-0.9	0.7	0.4	0.5
Mouth/teeth dental problems: Dentures	0.2	0.3	1.4	-1.2	0.8	0.2	-0.4	0.2	-0.3	-0.2	-0.3
Asthma	0.5	0.9	2.1	1.4	0.6	1.5	-1.0	1.0	-0.3	0.5	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.7	0.8	0.9	-0.1	0.9	-1.1	1.3	1.2	0.6
Medication: Cholesterol lowering	0.4	0.7	2.3	-0.9	-0.2	-1.5	0.7	-0.6	0.0	-1.1	0.1
Depression (self-reported)	2.3	2.7	6.5	-2.0	-0.9	-2.6	1.6	-1.5	1.2	1.5	1.6
Medication: Lansoprazole	0.5	0.5	2.0	1.1	0.5	1.4	-0.4	-0.0	-0.0	-0.5	-0.7
Prospective memory result	0.7	0.9	3.1	1.7	-0.5	1.2	-0.8	0.9	-0.3	-0.3	-0.8
Lung cancer (father)	1.0	1.1	3.9	-0.1	-0.2	-0.2	0.9	-0.7	1.5	2.0	1.2
Illnesses of mother	0.5	0.6	2.9	-0.2	-0.5	-1.7	0.7	-0.8	-0.2	-0.1	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	3.9	12.4	20.8	-2.8	2.0	-2.9	4.5	-4.2	3.6	2.8	4.6
Pulse wave Arterial Stiffness index	0.2	0.3	1.1	-1.1	-0.0	-0.9	0.2	0.1	0.1	0.4	0.3
Impedance of arm (left)	0.8	3.7	9.2	2.6	1.4	3.0	0.3	-0.2	1.8	2.9	0.3
Arm fat mass (right)	0.2	0.7	2.2	-0.9	1.5	0.3	0.6	-0.7	0.8	0.6	0.5
Trunk predicted mass	3.2	18.3	36.6	-6.0	-0.2	-4.8	4.9	-4.7	2.8	2.0	5.3
Standing height	3.6	35.6	64.3	-5.6	0.5	-4.7	7.6	-7.2	5.7	5.1	8.0
Length of working week for main job	0.2	0.2	0.6	-0.8	0.7	-0.3	-0.3	0.4	-0.3	-0.2	-0.0
Exposure to tobacco smoke at home	0.8	0.8	2.4	1.1	1.5	1.6	-0.4	0.4	0.2	0.5	-0.5
Breastfed as a baby	0.6	0.7	1.7	-0.2	-0.1	-0.5	1.3	-1.3	0.9	0.1	1.0
Tense / ‘highly strung’	0.8	1.3	3.0	-0.0	0.6	-1.1	1.2	-0.9	1.4	1.7	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	2.1	3.2	5.2	-1.2	1.4	-1.1	2.1	-2.2	1.9	1.9	2.3
Hair/balding pattern: Pattern 4	1.3	3.1	10.1	-1.2	3.2	0.1	1.5	-1.3	1.8	1.8	1.8
Birth weight of first child	0.7	1.4	2.2	-1.3	1.2	1.2	1.0	-0.8	1.5	1.3	0.9
Peak expiratory flow (PEF)	2.4	5.5	11.5	-1.8	0.7	-1.3	3.3	-3.4	2.6	1.1	2.8
Pulse wave reflection index	0.2	0.2	0.9	0.9	0.2	-0.4	0.3	-0.1	0.3	0.5	0.2
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.1	-0.2	0.2	-0.6	-0.8	1.0	-0.6	0.2	-0.4
Loud music exposure frequency	0.0	0.0	0.2	-0.1	-0.3	0.2	0.1	0.1	-0.1	-0.4	0.1
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	2.1	-1.0	-1.0	-1.4	1.2	-1.1	0.3	-0.4	1.0
Mouth/teeth dental problems: Bleeding gums	5.7	7.4	12.5	-0.7	2.3	0.3	3.1	-2.9	3.3	3.5	3.4
Blood clot in the leg (DVT)	0.4	0.6	2.7	0.9	0.8	1.6	0.2	-0.3	0.6	0.1	-0.0
Medication: Paracetamol	2.3	3.9	6.6	-0.4	1.9	0.3	2.6	-2.5	2.5	1.9	2.1
Headache pain in last month	1.2	2.1	3.9	1.5	-0.1	1.9	0.9	-1.2	2.0	2.0	0.9
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	2.2	0.7	-1.3	0.4	-1.5	1.5	-1.4	-0.7	-1.1
Glaucoma (self-reported)	0.9	1.0	3.1	1.8	-0.4	1.4	0.6	-0.7	0.9	1.1	0.5
Gout (self-reported)	1.1	1.5	7.9	2.8	0.8	1.4	0.3	-0.5	0.9	0.5	-0.2
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	2.1	-0.3	-1.3	0.2	-1.4	1.4	-1.5	-1.4	-1.4
Medication: Amlodipine	0.2	0.3	1.0	0.4	1.0	0.8	0.5	-0.5	0.6	0.1	0.3
Medication: Ventolin 100micrograms inhaler	0.9	1.2	4.8	1.4	0.5	2.2	-0.3	0.4	0.5	1.3	-0.2
Birth weight	0.2	0.4	0.8	-0.2	0.7	-0.6	-0.9	0.8	-0.7	0.1	-0.3
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.4	-0.6	0.5	-0.3	-0.6	0.3	-0.3	0.0	-0.6
High blood pressure (siblings)	0.4	0.6	1.7	1.3	1.1	0.8	-0.5	0.5	-0.3	-0.4	-0.8
Forced vital capacity (FVC), Best measure	3.7	13.5	23.1	-3.3	2.0	-3.1	4.6	-4.3	3.5	3.0	4.8
Body fat percentage	0.2	0.9	3.3	0.8	1.3	1.8	-0.6	0.6	0.1	0.1	-0.9
Leg fat percentage (right)	0.6	2.2	4.3	1.0	0.4	1.4	-1.9	1.9	-1.3	-1.1	-2.1
Arm fat-free mass (right)	2.7	14.0	29.1	-5.4	-0.0	-4.4	4.3	-4.2	2.3	1.2	4.5
Exposure to tobacco smoke outside home	0.3	0.5	1.5	1.2	1.0	0.7	-0.4	0.4	-0.0	-0.1	-0.6
Comparative body size at age 10	0.4	1.2	2.2	0.4	-0.4	0.7	-1.5	1.4	-1.4	-0.9	-1.4
Number of full brothers	0.3	0.3	1.7	-1.3	-0.2	-0.2	0.5	-0.6	0.2	-0.4	0.2
Worry too long after embarrassment	0.5	0.9	2.4	-0.0	1.4	-0.8	0.6	-0.3	0.8	1.6	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	3.4	-0.5	0.0	-1.9	0.3	-0.4	-0.2	-0.2	0.4
Wheeze or whistling in the chest in last year	0.2	0.4	1.2	0.6	0.9	1.1	-0.2	0.0	0.4	1.0	-0.0
Number of children fathered	1.3	1.5	4.9	-1.5	-1.4	-2.2	0.8	-0.8	-0.2	-0.5	1.1
Reason for reducing amount of alcohol drunk: Health precaution	2.3	2.7	4.3	-0.0	-0.7	-2.1	-2.0	1.8	-2.1	-1.6	-1.7
Age at first live birth	1.2	2.1	9.3	-1.2	-2.0	-3.0	0.3	0.2	-0.9	-0.4	0.9
Pulse wave peak to peak time	0.1	0.1	0.5	0.7	-0.2	0.3	0.2	-0.5	0.1	-0.3	0.1
Health satisfaction	0.4	0.5	2.0	0.6	-0.8	1.4	-0.5	0.5	-0.2	0.0	-0.7
Shortness of breath walking on level ground	0.1	0.1	0.4	0.0	-0.1	0.6	-0.0	-0.2	0.1	0.5	0.3
Qualifications: College or University degree	2.2	6.9	12.7	-1.6	0.3	-0.7	3.0	-2.9	3.0	3.6	3.6
Eye problems/disorders: None of the above	0.9	1.0	1.9	-1.2	1.1	-1.4	1.1	-1.2	0.5	-0.2	0.9
Mouth/teeth dental problems: Loose teeth	1.1	1.3	3.1	-0.7	0.9	-0.3	1.2	-1.1	1.4	1.8	1.2
Emphysema/chronic bronchitis	0.2	0.2	1.0	0.3	1.0	0.5	-0.4	0.1	0.1	0.0	-0.7
Medication for pain relief, constipation, heartburn	1.3	2.2	5.4	-1.3	-2.3	-0.9	-1.4	1.4	-1.8	-1.3	-1.0
Neck or shoulder pain in last month	2.3	3.3	6.4	-0.9	1.4	0.7	2.3	-2.1	2.5	1.9	1.8
Medication: Blood pressure	0.6	1.0	2.1	-0.2	1.4	-0.2	1.1	-1.3	1.3	0.7	0.9
Angina (self-reported)	0.8	1.0	2.1	-0.4	-1.2	-0.2	-0.9	1.1	-1.1	-1.5	-1.0
Migraine (self-reported)	0.8	1.0	2.2	1.3	0.8	0.7	-1.4	0.9	-0.7	-0.3	-1.5
Medication: Ibuprofen	0.2	0.2	1.1	0.1	-0.0	-1.0	0.5	-0.5	0.4	0.3	0.3
Medication: Allopurinol	2.6	3.5	9.6	3.1	1.7	1.9	1.0	-1.4	2.1	2.1	0.7
Medication: Omeprazole	0.2	0.2	0.7	0.8	0.3	-0.8	0.0	0.0	0.1	0.3	0.2
Medication: Seretide 50 evohaler	2.5	2.9	6.7	2.6	-1.4	1.8	-1.7	1.7	-1.2	-1.0	-1.8
Mean time to correctly identify matches	0.2	0.4	1.3	-0.3	0.3	0.0	-0.9	1.1	-0.9	-0.4	-0.6
Heart disease (mother)	0.6	0.7	1.5	0.0	1.2	0.7	-0.8	0.8	-0.6	-0.9	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	0.8	-0.0	0.7	-0.3	0.6	-0.3	0.8	0.9	0.7
Whole body fat mass	0.2	0.8	1.4	-1.0	1.2	0.2	1.0	-1.0	1.0	0.8	0.8
Leg fat mass (right)	0.0	0.1	0.5	-0.7	0.7	0.2	0.1	-0.0	0.1	0.0	-0.1
Arm predicted mass (right)	2.8	14.3	26.8	-5.2	0.0	-4.2	4.5	-4.4	2.6	1.4	4.6
Pulse rate, automated reading	0.3	1.1	3.0	-1.7	0.5	0.2	1.1	-0.9	1.2	1.1	0.9
Alcohol intake frequency.	0.1	0.2	1.0	-0.4	0.3	-0.3	0.1	-0.2	-0.2	-1.0	0.1
Comparative height size at age 10	1.8	9.7	18.2	-2.6	-0.4	-2.5	4.1	-3.9	2.7	2.4	4.3
Number of full sisters	0.2	0.2	0.6	0.5	0.1	-0.8	0.6	-0.6	0.4	0.1	0.5
Suffer from ‘nerves’	0.7	1.0	2.0	-0.9	-0.3	-1.4	1.3	-0.9	1.0	0.9	1.1
Overall health rating	0.3	0.7	1.8	0.3	1.2	1.4	-0.7	0.9	0.1	0.6	-0.9
Chest pain or discomfort	1.9	2.7	4.5	-1.4	0.1	-0.7	1.9	-1.9	2.1	1.9	1.9
Had major operations	2.6	3.0	6.9	0.1	-0.1	0.1	2.4	-2.6	2.4	1.2	2.1
Age at last live birth	0.6	0.9	2.7	-1.3	-0.8	-1.6	-0.3	0.9	-1.0	-0.1	0.2
Family relationship satisfaction	3.7	4.5	9.3	-1.8	0.8	-0.5	2.2	-2.1	2.5	3.1	2.6
Leg pain on walking	0.6	0.8	1.8	0.6	0.2	1.3	0.7	-0.8	1.2	1.2	0.4
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	3.0	1.4	0.3	1.7	-1.0	1.0	-1.0	-1.3	-1.5
Commuting to job workplace: Car/motor vehicle	0.9	1.1	2.7	-1.7	-1.0	-1.4	1.1	-0.8	0.4	-0.2	0.9
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	2.7	0.3	0.6	1.3	-1.5	1.6	-1.2	-0.9	-1.6
Medication: Aspirin	0.2	0.3	0.6	0.8	0.3	0.5	-0.4	0.6	-0.3	-0.5	-0.5
Supplements: Vitamin C	0.6	0.7	1.7	-0.8	-0.1	-0.7	0.8	-0.6	0.7	1.3	1.1
Knee pain experienced in last month	0.4	0.5	1.6	-0.8	0.9	-0.1	0.3	-0.6	0.9	1.3	0.4
Hypertension (Self-reported)	1.4	3.8	8.9	1.2	3.0	2.4	1.0	-1.2	2.4	2.3	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.6	1.8	0.1	-1.2	-1.4	0.8	-0.9	0.2	-0.3	0.7
Illnesses of father: Heart disease	1.4	1.9	6.8	0.0	-1.7	-2.6	0.4	-0.1	-1.0	-2.0	0.1
Illnesses of siblings: Diabetes	0.6	0.7	1.6	1.1	0.5	1.0	-1.0	1.3	-0.5	-0.3	-0.8
Smoking status: Previous	1.2	1.9	3.3	-0.9	-0.1	-1.5	1.8	-1.8	1.5	0.8	1.6
Forced expiratory volume in 1-second (FEV1), predicted	4.3	8.9	16.5	-2.2	0.9	-2.2	3.6	-3.2	3.0	3.4	4.1
Whole body fat-free mass	3.0	16.9	32.5	-5.7	-0.2	-4.5	4.8	-4.6	2.9	2.1	5.1
Leg fat-free mass (right)	2.4	13.0	21.1	-4.6	0.3	-3.2	4.3	-4.3	3.0	2.3	4.5
Arm fat percentage (left)	0.2	0.7	2.9	0.4	1.2	1.7	-0.3	0.3	0.3	0.3	-0.6
Average weekly red wine intake	0.7	1.1	3.5	-1.3	-0.3	-1.9	1.0	-1.0	0.3	0.3	1.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.8	0.0	0.9	-0.5	-0.3	0.2	0.0	0.5	0.1
Mood swings	0.2	0.4	0.9	-0.0	0.3	-1.0	-0.7	0.9	-0.8	-0.1	-0.6
Loneliness, isolation	1.6	2.2	7.3	-1.9	0.2	-2.7	1.2	-1.1	0.9	1.1	1.4
Long-standing illness, disability or infirmity	0.2	0.3	0.7	-0.1	0.9	-0.6	-0.5	0.7	-0.3	0.3	-0.3
Ever had bowel cancer screening	0.6	0.7	1.3	-1.1	-0.3	-0.9	1.1	-1.0	0.4	-0.6	0.7
Diabetes diagnosed by doctor	0.7	1.1	4.2	-1.2	-1.0	-2.0	-0.2	0.4	-0.9	-1.1	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.4	0.4	1.1	0.6	0.2	0.1	0.6	1.5	0.5
Friendships satisfaction	1.4	1.7	3.6	0.6	1.1	1.0	1.3	-1.3	1.9	1.9	1.0
Qualifications: nursing, teaching	0.2	0.4	1.9	1.4	-0.0	0.1	0.1	-0.2	0.4	0.8	0.4
Commuting to job workplace: Walk	1.2	1.3	3.0	-1.7	-1.0	-0.8	1.3	-1.1	0.6	0.6	1.5
Eye problems/disorders: Cataract	3.8	4.4	8.5	2.5	-2.9	1.9	-2.0	2.0	-1.6	-1.4	-2.2
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	3.5	0.2	1.4	0.6	1.6	-1.9	1.5	0.8	1.2
Medication for cholesterol	0.3	0.5	2.4	-0.3	-1.5	-0.9	0.3	-0.3	-0.1	-0.0	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.3	0.0	0.5	0.3	0.5	-0.3	0.1	-0.4	0.2
Back pain experienced in last month	0.7	1.1	3.6	0.7	1.5	1.9	0.3	-0.2	0.9	1.1	0.1
Mineral and other dietary supplements	0.1	0.1	0.5	0.3	0.7	0.1	-0.2	0.1	-0.0	0.6	0.3
Breast cancer (self-reported)	0.8	0.9	3.3	1.8	-0.0	1.7	-0.6	0.4	-0.1	-0.1	-0.7
Asthma (self-reported)	0.4	0.7	2.1	1.3	0.7	1.4	-0.6	0.6	0.1	0.8	-0.4
Osteoporosis (self-reported)	0.5	0.6	1.1	-0.5	-0.6	0.0	-0.8	1.0	-1.1	-0.9	-0.8
Osteoarthritis (self-reported)	1.4	1.8	4.2	0.9	0.9	0.1	1.3	-1.4	1.9	2.1	1.3
Medication: Aspirin	0.6	0.8	1.5	0.5	-0.0	0.1	-1.1	1.2	-0.9	-1.2	-1.0
Medication: Gliclazide	0.6	0.7	3.0	-1.7	1.3	0.8	0.2	-0.3	0.3	0.2	-0.2
Illnesses of father: None of the above (group 1)	1.9	2.3	6.0	1.6	0.6	2.4	-1.9	1.8	-0.6	0.8	-1.4
Smoking status: Current	0.5	0.8	3.0	-1.7	0.9	-1.4	0.4	-0.2	-0.4	-0.5	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.5	6.0	-1.3	1.8	-0.2	2.2	-2.1	2.5	1.8	2.1
Whole body water mass	2.8	16.2	31.5	-5.6	-0.1	-4.3	4.7	-4.6	2.8	2.0	5.0
Leg predicted mass (right)	2.5	13.2	21.9	-4.7	0.3	-3.3	4.3	-4.3	3.0	2.3	4.6
Arm fat mass (left)	0.2	0.8	2.1	-1.4	1.2	0.0	0.9	-0.9	0.8	0.7	0.8
Number of self-reported non-cancer illnesses	0.6	1.0	2.7	-0.1	0.7	1.6	0.6	-0.7	1.3	1.6	0.5
Average weekly champagne plus white wine intake	0.3	0.4	1.6	1.2	0.9	0.2	-0.5	0.5	-0.1	0.4	-0.2
Miserableness	1.1	2.0	3.0	0.2	1.1	-1.3	1.7	-1.6	1.7	1.6	1.4
Guilty feelings	1.7	2.5	7.7	-1.4	-0.3	-2.8	1.5	-1.4	1.0	1.3	1.9
Wears glasses or contact lenses	0.2	0.2	0.8	-0.3	0.9	0.6	-0.3	0.2	-0.3	-0.3	-0.5
Ever taken oral contraceptive pill	1.2	1.3	5.0	-0.8	-0.9	-2.2	0.5	-0.3	-1.0	-1.7	0.1
Hearing aid user	0.5	0.6	1.7	-1.2	-1.3	-0.9	0.0	-0.3	-0.4	-0.7	0.2
Mother’s age at death	1.2	1.5	5.4	-2.2	-0.6	-2.3	0.6	-0.5	-0.1	0.1	1.0
Financial situation satisfaction	0.4	0.5	1.3	-0.8	1.1	0.7	-0.1	0.3	0.4	1.0	-0.2
Tinnitus: Yes, now most or all of the time	0.4	0.4	2.3	0.2	1.5	0.1	-0.6	0.4	-0.4	-0.3	-0.4
Commuting to job workplace: Public transport	0.8	1.0	4.0	0.1	1.0	2.0	-0.9	0.8	0.0	1.1	-0.6
Eye problems/disorders: Glaucoma	1.3	1.5	3.6	1.3	0.4	1.9	0.7	-0.8	1.4	1.7	0.7
Medication: Blood pressure	0.4	0.8	2.3	1.0	1.5	1.5	-0.2	-0.1	0.6	0.8	-0.1
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.6	-0.7	-0.0	-0.5	1.1	-1.0	1.2	1.1	1.2
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.0	0.5	-0.9	1.0	-0.4	0.1	-0.4	-0.9	-0.8
High cholesterol (Self-reported)	0.5	0.8	2.5	1.6	-0.1	0.7	1.1	-0.9	1.0	0.5	0.5
Medication: Bendroflumethiazide	0.4	0.7	1.7	0.9	0.2	0.9	0.4	-0.4	1.1	1.3	0.5
Medication: Paracetamol	0.6	1.0	1.9	-0.2	1.0	-0.5	1.4	-1.3	1.0	0.8	1.1
Medication: Lisinopril	3.9	5.0	19.0	2.9	0.6	4.4	-1.9	1.8	-0.6	-0.3	-2.3
Medication: Atorvastatin	0.4	0.5	1.7	0.6	1.3	0.1	-0.3	0.2	-0.4	-1.0	-0.6
Illnesses of father: High blood pressure	1.1	1.4	2.9	0.2	1.1	0.5	1.5	-1.2	1.7	1.3	1.2
Alcohol drinker status: Never	0.4	0.4	0.9	-0.2	0.4	0.5	-1.0	0.7	-0.7	-0.6	-0.9
Ever smoked	1.6	2.8	6.6	-2.6	-0.3	-1.6	2.1	-2.0	1.3	0.5	1.7
Basal metabolic rate	2.5	13.7	24.8	-5.0	0.1	-3.8	4.3	-4.2	2.7	2.0	4.6
Leg fat percentage (left)	0.7	2.7	5.2	1.1	0.6	1.6	-2.1	2.0	-1.4	-1.2	-2.3
Arm fat-free mass (left)	2.0	10.0	22.8	-4.8	0.4	-3.5	3.6	-3.5	2.0	1.1	3.8
Number of operations (self-reported)	0.3	0.4	0.9	0.1	0.2	0.6	0.8	-0.9	1.0	0.2	0.5
Average weekly beer plus cider intake	0.6	0.8	2.0	-0.8	-1.4	-0.6	-0.7	0.7	-0.9	-1.0	-0.6
Irritability	0.2	0.4	2.0	-0.3	0.5	-1.4	-0.4	0.5	-0.4	0.1	-0.4
Risk taking	0.1	0.2	0.7	0.5	-0.5	-0.8	-0.1	0.6	-0.2	0.3	0.2
Ever had prostate specific antigen (PSA) test	0.9	1.1	3.8	0.1	-1.5	-1.2	0.1	-0.3	-1.0	-1.9	-0.3
Fractured/broken bones in last 5 years	1.0	1.3	4.1	-0.7	2.0	-0.8	0.6	-0.9	0.7	1.4	1.1
Age started oral contraceptive pill	2.3	2.8	5.3	0.8	-1.3	0.7	-2.3	2.2	-2.0	-1.4	-1.9
Diastolic blood pressure, automated reading	1.4	4.5	7.6	-0.3	2.6	2.1	1.9	-1.7	2.8	2.7	1.6
Ever depressed for a whole week	0.6	0.8	4.7	2.2	-0.3	-0.6	0.3	-0.2	0.2	0.9	0.2
Unable to work because of sickness or disability	0.7	0.9	4.7	-2.2	0.5	-1.0	-0.2	0.7	-0.5	-0.1	-0.3
Commuting to job workplace: Cycle	1.3	1.5	4.6	-1.9	0.1	-2.1	0.9	-1.2	0.3	0.1	1.3
Myopia	0.1	0.1	0.3	-0.5	0.4	-0.5	-0.1	-0.1	0.0	0.6	0.3
Vascular/heart problems diagnosed by doctor	1.1	3.0	8.6	-0.8	-2.9	-2.1	-0.7	0.9	-2.1	-2.1	-0.6
Cholesterol lowering medication	0.4	0.6	2.2	1.5	1.4	0.4	-0.2	0.1	0.0	-0.3	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.2	0.3	0.2	-0.4	-0.5	0.5	-0.2	0.0	-0.4
Pain experienced in last month	0.5	0.8	3.1	-0.5	-0.6	-1.8	-0.4	0.5	-1.1	-0.9	-0.1
Supplements: Calcium	0.8	0.9	2.8	-0.8	-0.1	-1.7	-0.6	0.8	-1.2	-1.1	-0.6
Basal cell carcinoma (self-reported)	0.5	0.6	1.2	-0.7	-1.1	-1.1	0.8	-0.7	0.6	0.1	0.9
Heart attack/myocardial infarction (self-reported)	0.8	1.0	1.5	-0.8	0.1	-1.2	-1.1	0.9	-1.2	-1.1	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.4	0.8	0.9	1.6	-0.0	-0.2	0.4	0.0	-0.2
Heart disease (siblings)	0.7	0.9	2.3	0.3	0.3	1.5	-0.7	0.7	-0.7	-1.3	-1.1
Alcohol drinker status: Previous	1.0	1.1	3.0	-0.6	-0.8	-1.7	1.3	-1.3	0.7	-0.2	1.1
Pack years of smoking	0.7	1.1	2.7	1.6	-1.6	-0.4	-0.9	0.9	-0.9	-0.8	-0.7
Impedance of whole body	0.6	2.9	9.6	3.1	0.8	2.8	-0.2	0.4	1.0	1.8	-0.4
Leg fat mass (left)	0.0	0.2	0.8	-0.6	0.9	0.3	-0.1	0.1	0.0	-0.0	-0.2
Arm predicted mass (left)	2.1	10.8	26.3	-5.1	0.4	-3.4	3.7	-3.6	2.1	1.2	3.9