[Hub]/) : Traits : Trunk fat-free mass : ← →

chr12:27,587,038-30,170,382

Best TWAS P=9.52e-17 · Best GWAS P=8.5e-17 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	GTEx	Cells Transformed fibroblasts	RP11-967K21.1	0.07	0.07	lasso	2	0.07	3.7e-06	-8.1	8.3	9.5e-17	-0.96	0.03	0.97	TRUE
6	GTEx	Artery Tibial	RP11-996F15.2	0.44	0.40	enet	28	0.44	1.2e-37	5.4	5.5	4.3e-08	0.07	0.00	1.00	TRUE
30	GTEx	Skin Sun Exposed Lower leg	CCDC91	0.09	0.01	enet	8	0.01	2.6e-02	-8.1	-8.2	2.0e-16	0.85	0.06	0.91	FALSE
21	GTEx	Heart Atrial Appendage	RP11-967K21.1	0.08	0.09	lasso	1	0.08	2.3e-04	-8.1	8.1	4.6e-16	-0.91	0.03	0.93	FALSE
12	GTEx	Cells Transformed fibroblasts	CCDC91	0.10	0.10	lasso	5	0.09	5.5e-07	-7.8	-8.0	1.9e-15	0.85	0.14	0.86	FALSE
42	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CCDC91	0.09	0.11	lasso	2	0.12	2.3e-05	-7.8	-7.8	9.1e-15	0.91	0.07	0.91	FALSE
38	The Cancer Genome Atlas	Breast Invasive Carcinoma	CCDC91	0.04	0.04	lasso	3	0.03	1.8e-06	-7.6	-7.6	2.5e-14	0.94	0.17	0.83	FALSE
28	GTEx	Skin Not Sun Exposed Suprapubic	CCDC91	0.26	0.05	lasso	15	0.04	4.1e-03	-8.3	-7.5	5.9e-14	0.87	0.04	0.96	FALSE
43	The Cancer Genome Atlas	Thyroid Carcinoma	CCDC91	0.40	0.12	blup	175	0.14	4.9e-13	-7.9	-7.4	1.6e-13	0.72	0.07	0.93	FALSE
4	GTEx	Artery Aorta	RP11-967K21.1	0.07	0.02	lasso	7	0.01	7.9e-02	4.9	7.3	2.6e-13	-0.83	0.07	0.79	FALSE
15	GTEx	Colon Transverse	CCDC91	0.11	0.01	lasso	6	0.00	4.6e-01	-7.7	-7.3	2.6e-13	0.80	0.09	0.75	FALSE
23	GTEx	Muscle Skeletal	RP11-967K21.1	0.04	0.01	lasso	9	0.00	2.9e-01	-7.7	7.3	3.6e-13	-0.90	0.07	0.79	FALSE
20	GTEx	Heart Atrial Appendage	CCDC91	0.10	0.06	lasso	8	0.04	4.4e-03	-7.8	-7.2	5.6e-13	0.85	0.05	0.90	FALSE
39	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CCDC91	0.06	0.02	blup	174	0.04	2.9e-05	3.9	-6.9	6.4e-12	0.79	0.38	0.59	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CCDC91	0.08	0.06	lasso	6	0.07	9.4e-09	-7.6	6.7	1.6e-11	-0.87	0.30	0.70	FALSE
41	The Cancer Genome Atlas	Lung Adenocarcinoma	CCDC91	0.09	0.01	blup	170	0.02	1.0e-03	-7.9	-6.4	1.7e-10	0.75	0.15	0.72	FALSE
34	GTEx	Thyroid	CCDC91	0.15	0.12	enet	42	0.12	2.9e-09	-7.9	-6.0	2.6e-09	0.81	0.06	0.94	FALSE
36	NTR	Blood	CCDC91	0.01	0.01	blup	648	0.00	9.0e-03	3.3	-5.7	1.5e-08	0.75	0.26	0.41	FALSE
26	GTEx	Pituitary	RP11-967K21.1	0.20	0.04	lasso	7	0.04	4.4e-02	3.2	5.6	2.0e-08	-0.62	0.07	0.46	FALSE
17	GTEx	Esophagus Mucosa	CCDC91	0.18	0.04	enet	36	0.03	3.1e-03	4.9	-5.6	2.7e-08	0.53	0.14	0.68	FALSE
32	GTEx	Small Intestine Terminal Ileum	RP11-996F15.2	0.60	0.51	lasso	5	0.46	7.1e-12	5.4	5.5	4.6e-08	0.05	0.00	1.00	FALSE
27	GTEx	Prostate	RP11-996F15.2	0.49	0.36	enet	32	0.39	6.0e-11	5.2	5.5	4.8e-08	0.04	0.00	1.00	FALSE
9	GTEx	Breast Mammary Tissue (Male)	RP11-996F15.2	0.52	0.28	lasso	9	0.23	4.1e-06	5.2	5.4	5.5e-08	0.06	0.01	0.98	FALSE
2	GTEx	Adrenal Gland	CCDC91	0.16	0.01	lasso	16	0.03	3.5e-02	3.4	-5.4	6.2e-08	0.40	0.08	0.52	FALSE
8	GTEx	Breast Mammary Tissue	RP11-996F15.2	0.45	0.35	lasso	8	0.31	1.2e-16	5.4	5.4	8.4e-08	0.05	0.00	1.00	FALSE
3	GTEx	Adrenal Gland	RP11-996F15.2	0.62	0.55	lasso	7	0.55	3.0e-23	5.2	5.3	9.8e-08	0.05	0.00	1.00	FALSE
24	GTEx	Muscle Skeletal	RP11-996F15.2	0.24	0.26	lasso	11	0.25	9.3e-25	5.4	5.3	1.4e-07	0.06	0.00	1.00	FALSE
10	GTEx	Breast Mammary Tissue (Female)	RP11-996F15.2	0.42	0.38	lasso	1	0.35	3.5e-11	5.2	5.2	1.5e-07	0.05	0.00	1.00	FALSE
16	GTEx	Colon Transverse	RP11-996F15.2	0.31	0.32	lasso	1	0.31	3.5e-15	5.2	5.2	1.5e-07	0.05	0.00	1.00	FALSE
31	GTEx	Skin Sun Exposed Lower leg	RP11-996F15.2	0.50	0.48	enet	21	0.50	1.5e-47	5.4	5.2	1.6e-07	0.05	0.00	1.00	FALSE
18	GTEx	Esophagus Mucosa	RP11-996F15.2	0.39	0.43	lasso	7	0.45	6.2e-33	5.2	5.2	1.8e-07	0.06	0.00	1.00	FALSE
25	GTEx	Pancreas	RP11-996F15.2	0.56	0.46	enet	22	0.48	1.8e-22	5.2	5.2	1.9e-07	0.04	0.00	1.00	FALSE
19	GTEx	Esophagus Muscularis	RP11-996F15.2	0.56	0.45	enet	31	0.47	1.3e-31	5.2	5.2	2.0e-07	0.04	0.00	1.00	FALSE
35	GTEx	Thyroid	RP11-996F15.2	0.54	0.54	lasso	8	0.55	9.1e-50	5.4	5.2	2.0e-07	0.05	0.00	1.00	FALSE
5	GTEx	Artery Aorta	RP11-996F15.2	0.35	0.28	lasso	4	0.28	1.5e-15	5.2	5.2	2.1e-07	0.05	0.00	1.00	FALSE
7	GTEx	Brain Cerebellum	RP11-996F15.2	0.25	0.15	lasso	4	0.10	7.6e-04	5.2	5.2	2.1e-07	0.05	0.01	0.93	FALSE
40	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ERGIC2	0.04	0.03	lasso	2	0.03	1.3e-04	5.2	-5.2	2.1e-07	-0.04	0.01	0.99	FALSE
33	GTEx	Stomach	RP11-996F15.2	0.35	0.41	lasso	3	0.40	1.4e-20	5.2	5.2	2.3e-07	0.04	0.00	1.00	FALSE
11	GTEx	Cells EBV-transformed lymphocytes	RP11-996F15.2	0.27	0.24	lasso	4	0.23	6.0e-08	5.2	5.1	2.7e-07	0.05	0.01	0.99	FALSE
14	GTEx	Colon Sigmoid	RP11-996F15.2	0.42	0.27	lasso	7	0.29	7.7e-11	5.2	5.1	2.8e-07	0.06	0.00	1.00	FALSE
29	GTEx	Skin Not Sun Exposed Suprapubic	RP11-996F15.2	0.44	0.28	enet	55	0.28	1.1e-15	5.2	5.1	2.8e-07	0.05	0.00	1.00	FALSE
22	GTEx	Lung	RP11-996F15.2	0.50	0.46	lasso	5	0.46	1.9e-39	5.2	5.1	2.9e-07	0.05	0.00	1.00	FALSE
37	ROSMAP	Brain Pre-frontal Cortex	RP11-996F15.2	0.21	0.22	lasso	7	0.24	5.1e-30	5.2	5.1	3.0e-07	0.06	0.00	1.00	FALSE