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Genes
Traits
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Traits
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Trunk fat-free mass
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chr12:45,890,331-47,542,807
Best TWAS P=2.23e-21 · Best GWAS P=1.84e-24 conditioned to 0.00489
45.8M
46M
46.2M
46.4M
46.6M
46.8M
47M
47.2M
47.4M
47.6M
0
5
10
15
20
25
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
SLC38A2
0.10
0.06
blup
30
0.05
8.3e-04
-10.2
9.5
2.2e-21
-0.91
0.01
0.92
TRUE
3
NTR
Blood
SLC38A1
0.12
0.07
lasso
6
0.08
8.4e-24
5.6
-5.7
1.6e-08
0.07
1.00
0.00
TRUE
5
The Cancer Genome Atlas
Soft Tissue Sarcoma
SLC38A2
0.06
0.01
blup
30
0.03
5.1e-03
-10.1
8.9
8.0e-19
-0.92
0.01
0.76
FALSE
2
METSIM
Adipose
SLC38A2
0.02
0.02
blup
341
0.01
5.8e-03
-9.3
8.7
4.4e-18
-0.87
0.07
0.87
FALSE
1
GTEx
Heart Left Ventricle
RP11-96H19.1
0.29
0.04
enet
33
0.13
1.7e-07
2.6
5.2
1.9e-07
-0.68
0.03
0.97
FALSE