Best TWAS P=2.23e-21 · Best GWAS P=1.84e-24 conditioned to 0.00489
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | RP11-96H19.1 | 0.29 | 0.04 | enet | 33 | 0.13 | 1.7e-07 | 2.6 | 5.2 | 1.9e-07 | -0.68 | 0.03 | 0.97 | FALSE |
| 2 | METSIM | Adipose | SLC38A2 | 0.02 | 0.02 | blup | 341 | 0.01 | 5.8e-03 | -9.3 | 8.7 | 4.4e-18 | -0.87 | 0.07 | 0.87 | FALSE |
| 3 | NTR | Blood | SLC38A1 | 0.12 | 0.07 | lasso | 6 | 0.08 | 8.4e-24 | 5.6 | -5.7 | 1.6e-08 | 0.07 | 1.00 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC38A2 | 0.10 | 0.06 | blup | 30 | 0.05 | 8.3e-04 | -10.2 | 9.5 | 2.2e-21 | -0.91 | 0.01 | 0.92 | TRUE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SLC38A2 | 0.06 | 0.01 | blup | 30 | 0.03 | 5.1e-03 | -10.1 | 8.9 | 8.0e-19 | -0.92 | 0.01 | 0.76 | FALSE |