Best TWAS P=3.23e-15 · Best GWAS P=2.79e-15 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | MAX | 0.15 | 0.16 | lasso | 2 | 0.16 | 1.2e-18 | -6.5 | 6.3 | 2.5e-10 | -0.80 | 0.94 | 0.06 | FALSE |
| 2 | GTEx | Muscle Skeletal | FNTB | 0.05 | 0.02 | lasso | 6 | 0.01 | 5.8e-02 | -5.7 | 5.6 | 2.6e-08 | -0.75 | 0.12 | 0.75 | FALSE |
| 3 | METSIM | Adipose | RAB15 | 0.10 | 0.04 | enet | 22 | 0.08 | 3.8e-12 | -4.9 | -5.1 | 3.0e-07 | 0.51 | 1.00 | 0.00 | FALSE |
| 4 | YFS | Blood | MAX | 0.04 | 0.02 | lasso | 4 | 0.02 | 2.8e-06 | -7.9 | 7.9 | 3.2e-15 | -0.99 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | FNTB | 0.14 | 0.06 | enet | 18 | 0.14 | 1.4e-13 | -2.0 | 5.6 | 2.3e-08 | -0.64 | 0.30 | 0.70 | FALSE |