TWAS hub - MAX

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1510	0.0350	1.4e-12	0.163	0.113	0.142	0.155	0.157	2.5e-19	1.3e-13	6.5e-17	2.1e-18	1.2e-18
2	YFS	Blood	0.0433	0.0201	1.0e-03	0.020	0.005	0.007	0.006	0.016	2.5e-07	8.6e-03	1.6e-03	2.5e-03	2.8e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Height	12.9	249.2	282.2	14.7	16.8
Standing height	12.9	128.2	146.4	10.5	12.1
Comparative height size at age 10	12.0	65.9	68.4	8.0	8.3
Blood Red Count	11.5	111.5	117.1	10.8	10.3
Sitting height	10.4	73.9	88.2	7.7	9.4
Trunk fat-free mass	8.9	51.1	62.1	6.3	7.9
Trunk predicted mass	8.9	50.7	61.6	6.3	7.8
Blood Platelet Count	8.8	102.0	134.6	-11.6	-8.3
Hand grip strength (right)	8.0	21.8	22.6	4.6	4.8
Emphysema/chronic bronchitis	7.8	8.8	10.8	-2.6	-3.3
Supplements: Vitamin C	7.5	8.9	9.5	-3.1	-2.9
Whole body fat-free mass	7.0	39.8	49.3	5.5	7.0
Chronic bronchitis/emphysema (mother)	6.9	8.0	8.7	-2.7	-3.0
Arm fat-free mass (right)	6.8	34.6	42.0	5.2	6.5
Blood Eosinophil Count	6.6	50.5	53.6	-7.3	-6.9
Whole body water mass	6.6	37.7	46.8	5.3	6.8
Arm predicted mass (right)	6.4	32.8	41.8	4.9	6.5
Long-standing illness, disability or infirmity	6.3	9.7	12.2	-2.7	-3.5
Medication: Paracetamol	6.2	10.3	11.0	-3.3	-3.1
Medication for pain relief, constipation, heartburn	6.2	10.7	13.3	3.6	2.8
Hand grip strength (left)	6.1	16.0	18.9	3.6	4.4
Forced expiratory volume in 1-second (FEV1), predicted	6.0	12.5	14.9	3.2	3.9
Arm fat-free mass (left)	6.0	30.6	38.4	4.8	6.2
Basal metabolic rate	5.9	32.6	40.6	5.0	6.4
Arm predicted mass (left)	5.9	29.9	38.1	4.7	6.2
Medication: Aspirin	5.2	6.9	6.9	-2.6	-2.6
Asthma (self-reported)	4.9	9.8	10.4	-3.0	-3.2
Medication: Aspirin	4.8	6.3	6.4	-2.5	-2.5
Chronic bronchitis/emphysema (father)	4.7	5.5	6.4	-2.5	-2.2
Asthma	4.7	9.3	9.4	-3.1	-3.1
Alzheimer’s Disease (in father)	4.6	5.0	5.1	-2.2	-2.3
Leg fat-free mass (right)	4.5	23.9	30.7	4.1	5.5
Leg predicted mass (right)	4.5	23.9	30.6	4.1	5.5
Mouth/teeth dental problems	4.3	6.6	7.0	2.6	2.5
Heart attack/myocardial infarction (self-reported)	4.2	5.4	5.7	-2.3	-2.4
Respiratory disease	4.1	9.2	9.4	-3.0	-3.1
Ulcerative Colitis (UC)	4.0	7.6	7.9	-2.8	-2.7
Leg fat-free mass (left)	3.9	20.9	26.3	3.9	5.1
Leg predicted mass (left)	3.9	20.4	25.8	3.9	5.1
Illnesses of father: None of the above (group 1)	3.8	4.7	4.8	2.2	2.2
Knee pain experienced in last month	3.6	5.5	7.1	-2.7	-2.0
Type 2 Diabetes (T2D) (2012)	3.5	4.0	5.0	-2.2	-1.7
Blood White Count	3.5	25.9	27.3	-5.0	-5.2
Illnesses of father: Heart disease	3.5	4.9	6.2	-2.5	-1.9
Breast cancer (self-reported)	3.4	4.1	6.7	-1.2	-2.6
Medication: Paracetamol	3.4	5.3	5.7	-2.4	-2.2
Vitamin and mineral supplements	3.3	4.5	5.6	2.4	1.8
Supplements: Zinc	3.3	3.6	3.8	-1.9	-2.0
Schizophrenia (2014)	3.2	7.0	7.1	-2.7	-2.6
Number of self-reported non-cancer illnesses	3.2	5.6	6.0	-2.3	-2.4
Diverticular disease/diverticulitis (self-reported)	3.1	3.6	3.7	-1.9	-1.9
Heart attack	3.1	3.9	4.4	-1.9	-2.1
Diabetes (self-reported)	2.9	4.4	5.7	-1.8	-2.4
Body Mass Index (BMI) (2010)	2.8	3.8	6.2	-2.5	-1.2
Weight	2.8	13.7	17.9	3.1	4.2
Medication: Omeprazole	2.8	3.3	3.6	-1.9	-1.7
Lung FVC	2.7	13.9	16.0	-4.0	-3.4
Other serious medical condition/disability diagnosed by doctor	2.7	3.5	3.9	-1.8	-2.0
Wheeze or whistling in the chest in last year	2.7	4.8	6.6	-2.6	-1.7
Mean Putamen Volume	2.6	3.0	5.0	-1.0	-2.2
Breastfed as a baby	2.6	3.3	3.4	-1.8	-1.8
Birth weight of first child	2.6	4.8	6.5	1.7	2.6
Overall health rating	2.6	5.5	6.0	-2.2	-2.5
Commuting to job workplace: Cycle	2.6	3.2	3.6	1.7	1.9
Father’s age at death	2.5	3.4	4.7	2.2	1.4
Average weekly beer plus cider intake	2.5	3.6	4.0	1.8	2.0
Medication: Lansoprazole	2.4	2.7	4.0	-1.2	-2.0
Diabetes diagnosed by doctor	2.4	3.9	5.2	-1.6	-2.3
Primary Biliary Cirrhosis	2.3	3.3	4.1	-2.0	-1.6
Mouth/teeth dental problems: Dentures	2.3	4.0	4.0	-2.0	-2.0
Osteoarthritis (self-reported)	2.3	3.0	3.0	-1.7	-1.7
Alzheimer’s Disease (including proxy)	2.2	3.2	4.3	-1.5	-2.1
Smoking Status	2.2	5.4	5.9	-2.4	-2.2
Serious illness, injury or assault to yourself	2.2	2.7	2.9	-1.6	-1.7
Tinnitus: Yes, now most or all of the time	2.2	2.6	2.6	1.6	1.6
Irritable Bowel Disease (IBD)	2.1	5.0	5.5	-2.4	-2.1
Ever unenthusiastic/disinterested for a whole week	2.1	2.6	3.9	-2.0	-1.1
Ever highly irritable/argumentative for 2 days	2.1	2.6	3.7	-1.9	-1.2
Type 2 Diabetes (T2D) (2018)	2.0	3.8	5.1	-1.6	-2.3
Number of treatments/medications taken	2.0	3.6	4.3	-2.1	-1.7
Average weekly spirits intake	2.0	2.4	3.5	-1.2	-1.9
Severe depression (siblings)	2.0	2.2	3.4	-1.0	-1.8
Forced expiratory volume in 1-second (FEV1)	2.0	6.7	8.6	2.2	2.9
Pulse wave reflection index	1.9	2.4	2.4	-1.6	-1.5
Heart disease (mother)	1.9	2.3	2.4	1.5	1.5
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	3.0	-1.3	-1.7
Heel T-Score	1.8	14.1	16.6	-3.4	-4.1
Number of children fathered	1.8	2.1	2.7	-1.7	-1.2
Medication: Gliclazide	1.8	2.0	2.9	-1.1	-1.7
Intelligence (Savage-Jansen 2018)	1.7	5.1	6.4	-2.5	-1.9
Pack years adult smoking proportion	1.7	2.6	2.7	-1.6	-1.6
Stomach or abdominal pain in last month	1.7	2.1	2.3	-1.5	-1.4
Birth weight	1.7	3.6	4.2	1.7	2.1
Smoking status: Current	1.7	2.8	3.1	-1.6	-1.8
Wears glasses or contact lenses	1.7	1.9	2.0	-1.4	-1.4
Systolic Blood Pressure	1.6	8.0	8.9	2.7	3.0
Past tobacco smoking	1.6	3.0	4.1	2.0	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.5	3.2	-1.8	-1.3
Had major operations	1.6	1.9	3.0	-1.7	-0.9
Medication: Bendroflumethiazide	1.6	2.5	3.1	1.4	1.7
Fractured/broken bones in last 5 years	1.6	2.1	2.7	-1.6	-1.2
Bipolar Disorder or Schizophrenia	1.5	3.6	3.9	-2.0	-1.8
Coronary Artery Disease (CAD)	1.5	1.8	2.6	-0.9	-1.6
Ulcerative Colitis	1.5	2.2	3.2	-1.8	-1.1
Relative age of first facial hair	1.5	3.1	3.1	-1.8	-1.8
Forced vital capacity (FVC)	1.5	5.9	7.8	2.0	2.8
Medication: Simvastatin	1.5	2.2	3.2	-1.1	-1.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.7	5.4	2.0	2.3
Schizophrenia (2018)	1.4	3.0	3.3	-1.8	-1.6
Crohns Disease (2017)	1.4	3.0	3.2	-1.8	-1.6
Hearing difficulty/problems: Yes	1.4	2.2	3.1	1.8	1.1
Had other major operations	1.4	1.7	1.8	-1.2	-1.3
Falls in the last year	1.4	1.9	2.5	-1.1	-1.6
Hair/balding pattern: Pattern 3	1.4	2.0	2.5	1.2	1.6
Glaucoma (self-reported)	1.4	1.7	2.9	1.7	0.7
Ever depressed for a whole week	1.4	1.8	2.5	-1.6	-1.0
Pack years of smoking	1.4	2.1	2.1	-1.5	-1.4
Crohns Disease (2012)	1.3	2.1	2.7	-1.7	-1.2
Systolic blood pressure, automated reading	1.3	3.8	4.6	2.1	1.8
Multivitamins +/- minerals	1.3	1.6	2.1	-1.4	-1.1
Financial difficulties in last 2 years	1.3	1.8	2.1	-1.2	-1.5
Allergy	1.3	3.0	3.5	1.9	1.6
Depression (self-reported)	1.3	1.6	2.3	-1.0	-1.5
Medication: Seretide 50 evohaler	1.3	1.5	1.9	-1.0	-1.4
Schizophrenia vs Biploar Disorder	1.2	1.5	2.7	-1.6	-0.6
High cholesterol (Self-reported)	1.2	2.2	2.2	-1.5	-1.5
Diastolic blood pressure, automated reading	1.2	3.7	5.1	2.3	1.5
Lupus	1.1	1.7	1.9	1.3	1.4
Current tobacco smoking	1.1	1.8	2.1	-1.2	-1.4
Alcohol usually taken with meals	1.1	1.8	3.0	0.8	1.7
Loud music exposure frequency	1.1	1.2	1.9	-0.7	-1.4
Forced vital capacity (FVC), Best measure	1.1	4.1	4.7	1.9	2.2
Number of operations (self-reported)	1.1	1.6	2.9	-1.7	-0.6
HDL Cholesterol	1.0	1.6	2.8	-1.7	-0.7
Medication: Metformin	1.0	1.5	1.5	-1.2	-1.2
Average weekly fortified wine intake	1.0	1.2	2.1	1.5	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	1.4	1.2	1.1
Hip circumference	1.0	4.4	6.6	1.5	2.6
Medication: Cholesterol lowering	1.0	1.6	1.6	-1.3	-1.3
Prospective memory result	1.0	1.3	1.3	-1.1	-1.2
Eye problems/disorders: None of the above	1.0	1.1	1.7	-0.7	-1.3
Migraine (self-reported)	1.0	1.3	1.7	-1.3	-0.9
Miserableness	1.0	1.7	3.2	0.5	1.8
Illnesses of father: High blood pressure	1.0	1.2	2.3	1.5	0.3
Irritability	1.0	1.8	2.3	-1.5	-1.1
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	1.4	-1.0	-1.2
Supplements: Calcium	1.0	1.2	1.5	-1.2	-0.9
Ovarian Cancer	0.9	1.2	1.4	1.0	1.2
Eye problems/disorders: Diabetes related eye disease	0.9	0.9	1.2	-0.8	-1.1
Number of live births	0.9	1.3	1.7	1.3	0.9
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	2.1	1.4	0.9
Illnesses of siblings: Diabetes	0.9	1.1	1.5	-0.9	-1.2
Ever smoked	0.9	1.7	2.2	-1.5	-1.0
Age at First Birth	0.8	1.2	1.5	1.2	1.0
Sensitivity / hurt feelings	0.8	1.3	2.6	-1.6	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	1.8	1.3	0.3
Medication: Ventolin 100micrograms inhaler	0.8	1.1	1.1	-1.1	-1.0
Health satisfaction	0.8	1.0	1.4	-1.2	-0.8
Shortness of breath walking on level ground	0.8	1.0	1.4	-0.8	-1.2
Medication: Allopurinol	0.8	1.1	2.1	0.4	1.4
Smoking status: Previous	0.8	1.1	2.0	-1.4	-0.5
Eye problems/disorders: Glaucoma	0.8	1.0	1.3	1.1	0.8
Verbal and Numeric Reasoning (VNR)	0.7	1.6	2.2	-1.5	-1.0
Hearing difficulty/problems with background noise	0.7	1.2	1.2	1.1	1.1
Qualifications: None of the above	0.7	1.6	2.0	1.1	1.4
Length of working week for main job	0.7	0.8	1.4	-1.2	-0.4
Suffer from ‘nerves’	0.7	1.0	1.1	1.0	1.1
Arm fat percentage (left)	0.7	3.0	3.1	-1.7	-1.8
Ever had hysterectomy (womb removed)	0.6	0.7	0.7	0.8	0.8
Medication for hormone replacement therapy	0.6	0.7	1.3	-1.1	-0.4
Number of incorrect matches in round	0.6	1.0	1.8	0.5	1.4
Arm fat percentage (right)	0.6	2.4	2.4	-1.5	-1.5
Time employed in main current job	0.6	0.6	0.9	0.6	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.4	-1.2	-0.4
Peak expiratory flow (PEF)	0.6	1.4	2.1	0.8	1.4
Medication: Amlodipine	0.6	0.9	1.1	-1.1	-0.8
Medication: Blood pressure	0.6	1.1	1.6	-1.3	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.1	1.1	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.0	1.0	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	1.6	-1.2	-1.0
Commuting to job workplace: Public transport	0.6	0.7	0.7	-0.8	-0.8
Bipolar Disorder (2018)	0.5	0.7	0.7	-0.9	-0.9
Depression (Nagel 2018)	0.5	0.8	1.1	0.6	1.1
Prostate Cancer	0.5	0.7	1.3	0.4	1.1
Waist Hip Ratio (WHR)	0.5	2.5	3.2	-1.3	-1.8
Neuroticism	0.5	1.1	2.2	0.3	1.5
Frequency of depressed mood in last 2 weeks	0.5	0.8	0.8	0.8	0.9
Angina	0.5	0.7	1.0	-0.6	-1.0
Diabetes (mother)	0.5	0.6	1.0	0.5	1.0
Fed-up feelings	0.5	0.9	1.7	-1.3	-0.2
Medication: Levothyroxine sodium	0.5	0.8	0.9	0.9	0.9
Nervous feelings	0.5	1.0	1.1	0.9	1.1
Had menopause	0.5	0.6	1.3	-0.1	-1.1
Lung cancer (father)	0.5	0.5	0.7	0.8	0.6
Pulse wave Arterial Stiffness index	0.5	0.5	0.7	0.6	0.9
Tense / ‘highly strung’	0.5	0.9	1.5	-1.2	-0.5
Blood clot in the leg (DVT)	0.5	0.7	1.1	-0.6	-1.0
Leg fat percentage (right)	0.5	1.7	1.7	-1.3	-1.3
Chest pain or discomfort	0.5	0.7	0.9	-0.8	-0.9
Ever had bowel cancer screening	0.5	0.6	0.8	-0.6	-0.9
Ever had prostate specific antigen (PSA) test	0.5	0.6	0.8	-0.6	0.9
Myopia	0.5	0.7	0.8	0.9	0.7
Depressed Affect (Nagel 2018)	0.4	0.8	1.4	-0.4	1.2
Worry (Nagel 2018)	0.4	0.9	1.4	0.5	1.2
Major Depression (MDD)	0.4	0.5	0.7	-0.6	-0.8
Breast Cancer	0.4	1.0	1.6	-1.2	-0.7
BMI	0.4	2.5	3.2	-1.8	-1.3
Cardiovascular Disease	0.4	1.3	1.9	-1.4	-0.9
Hair Pigment	0.4	10.4	11.2	-3.4	-3.1
Age when periods started (menarche)	0.4	1.0	1.2	-0.9	-1.1
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	0.8	-0.1	-0.9
Qualifications: CSEs or equivalent	0.4	0.5	0.9	-0.4	-0.9
Body mass index (BMI)	0.4	1.9	2.3	-1.5	-1.2
Trunk fat mass	0.4	1.6	2.2	1.0	1.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	0.6	-0.7	-0.8
Noisy workplace	0.4	0.5	1.0	0.3	-1.0
Exposure to tobacco smoke at home	0.4	0.4	0.5	-0.5	-0.7
Exposure to tobacco smoke outside home	0.4	0.5	0.9	-0.9	-0.3
Angina (self-reported)	0.4	0.5	0.6	-0.7	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	0.5	0.7	-0.7
Average weekly red wine intake	0.4	0.6	1.1	-0.4	1.0
Mother’s age at death	0.4	0.5	1.0	1.0	0.3
Financial situation satisfaction	0.4	0.5	0.8	0.6	0.9
Leg fat percentage (left)	0.4	1.4	1.7	-1.3	-1.1
Unable to work because of sickness or disability	0.4	0.5	1.0	-1.0	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	0.8	-0.3	-0.9
Neuroticism (Nagel 2018)	0.3	0.7	1.0	-0.7	1.0
Lung FEV1/FVC ratio	0.3	1.4	1.5	1.1	1.2
Chronotype (morning person)	0.3	0.7	1.4	1.2	-0.1
Taking other prescription medications	0.3	0.4	0.6	-0.5	-0.8
High blood pressure (mother)	0.3	0.4	0.8	0.9	0.3
Fluid intelligence score	0.3	0.6	1.2	-1.1	-0.3
Neuroticism score	0.3	0.5	1.1	-0.0	1.0
High blood pressure (siblings)	0.3	0.5	1.0	1.0	0.1
Body fat percentage	0.3	1.3	1.3	-1.1	-1.1
Worry too long after embarrassment	0.3	0.5	0.6	0.6	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.5	0.5	0.7
Age at first live birth	0.3	0.6	0.7	0.7	0.8
Qualifications: College or University degree	0.3	1.0	1.4	-1.2	-0.8
Neck or shoulder pain in last month	0.3	0.4	0.5	-0.7	-0.6
Leg pain on walking	0.3	0.4	0.8	-0.9	0.0
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.7	-0.8	0.0
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.6	-0.8	-0.5
Commuting to job workplace: Walk	0.3	0.4	0.5	0.7	0.5
Eye problems/disorders: Cataract	0.3	0.4	0.6	0.4	0.8
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	0.6	-0.6	-0.7
Back pain experienced in last month	0.3	0.5	0.5	0.7	0.7
Hearing aid user	0.3	0.4	0.6	0.8	0.3
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.7	-0.8	-0.2
Age started oral contraceptive pill	0.3	0.4	0.7	0.9	-0.1
Vascular/heart problems diagnosed by doctor	0.3	0.9	1.3	0.7	1.1
Reaction Time	0.2	0.3	0.4	-0.5	-0.7
Bipolar Disorder (2011)	0.2	0.2	0.3	-0.6	0.2
HbA1C	0.2	0.2	0.4	-0.2	-0.6
Hair/balding pattern: Pattern 2	0.2	0.3	0.6	0.8	0.2
Impedance of arm (right)	0.2	0.9	1.6	-0.4	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	0.4	-0.6	-0.6
Pulse rate	0.2	0.3	0.6	0.2	0.8
Illnesses of mother	0.2	0.2	0.4	-0.1	0.6
Impedance of arm (left)	0.2	1.0	1.7	-0.5	-1.3
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	0.5	-0.5	-0.7
Gout (self-reported)	0.2	0.3	0.7	0.1	0.8
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.3	0.2	0.6
Whole body fat mass	0.2	0.9	1.4	0.6	1.2
Pulse rate, automated reading	0.2	0.5	0.7	-0.6	-0.8
Alcohol intake frequency.	0.2	0.4	0.8	0.9	0.1
Number of full sisters	0.2	0.2	0.4	0.3	0.6
Mineral and other dietary supplements	0.2	0.3	0.6	0.8	0.2
Average weekly champagne plus white wine intake	0.2	0.3	0.5	0.4	0.7
Ever taken oral contraceptive pill	0.2	0.3	0.3	-0.5	-0.6
Medication: Blood pressure	0.2	0.4	0.9	0.9	-0.1
Cholesterol lowering medication	0.2	0.2	0.4	0.3	-0.6
Leg fat mass (left)	0.2	0.7	1.1	0.5	1.1
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	0.0	-0.5
Fasting Glucose	0.1	0.1	0.3	0.0	-0.5
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.3	0.2	-0.5
Medication: Co-codamol	0.1	0.2	0.2	-0.4	-0.4
Diabetes (father)	0.1	0.2	0.2	0.4	0.4
Trunk fat percentage	0.1	0.5	0.6	-0.8	-0.6
Maternal smoking around birth	0.1	0.1	0.2	-0.5	-0.1
Relative age voice broke	0.1	0.2	0.3	-0.3	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.1	0.3	0.0	-0.5
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.2	-0.5	0.3
Supplements: Glucosamine	0.1	0.2	0.4	-0.6	-0.1
Medication: Atenolol	0.1	0.2	0.2	0.4	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.4	0.0	-0.7
Medication: Ramipril	0.1	0.1	0.1	0.3	-0.3
Alcohol intake versus 10 years previously	0.1	0.2	0.3	-0.1	-0.6
Worrier / anxious feelings	0.1	0.3	0.6	0.0	0.7
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.6	-0.1	0.8
Arm fat mass (right)	0.1	0.3	0.5	0.3	0.7
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.2	-0.4	-0.2
Number of full brothers	0.1	0.1	0.1	-0.3	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.2	0.2	-0.4
Medication: Ibuprofen	0.1	0.1	0.2	-0.1	0.5
Leg fat mass (right)	0.1	0.6	0.9	0.5	0.9
Family relationship satisfaction	0.1	0.2	0.3	0.1	-0.6
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.2	0.0	0.4
Loneliness, isolation	0.1	0.1	0.1	-0.4	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.2	-0.5	0.0
Friendships satisfaction	0.1	0.1	0.1	-0.3	-0.3
Qualifications: nursing, teaching	0.1	0.2	0.2	-0.4	-0.4
Medication for cholesterol	0.1	0.1	0.1	-0.4	0.1
Osteoporosis (self-reported)	0.1	0.2	0.2	-0.3	-0.5
Medication: Atorvastatin	0.1	0.1	0.1	-0.4	0.0
Alcohol drinker status: Never	0.1	0.1	0.2	-0.2	-0.4
Risk taking	0.1	0.1	0.1	-0.4	0.3
Pain experienced in last month	0.1	0.2	0.3	-0.1	-0.5
Basal cell carcinoma (self-reported)	0.1	0.1	0.1	-0.2	0.4
Heart disease (siblings)	0.1	0.2	0.3	-0.1	0.5
Alcohol drinker status: Previous	0.1	0.1	0.2	-0.3	-0.4
Impedance of whole body	0.1	0.3	0.6	-0.2	-0.8
LDL Cholesterol	0.0	0.0	0.0	-0.2	-0.2
Neuroticism (2016)	0.0	0.1	0.1	-0.3	-0.2
Rheumatoid Arthritis	0.0	0.1	0.1	-0.0	0.3
Triglycerides	0.0	0.0	0.1	0.2	-0.1
Allergy or Eczema	0.0	0.1	0.2	0.2	0.5
Hypothyroidism (self reported)	0.0	0.1	0.1	-0.1	-0.3
Tanning	0.0	0.1	0.2	0.4	0.1
Impedance of leg (right)	0.0	0.1	0.2	0.5	-0.2
Townsend deprivation index at recruitment	0.0	0.0	0.0	-0.2	-0.0
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.1	0.1	-0.3
High blood pressure	0.0	0.0	0.0	-0.0	-0.2
Impedance of leg (left)	0.0	0.1	0.2	0.5	0.2
Waist circumference	0.0	0.1	0.2	-0.2	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.0	0.0	0.1	0.1
Pain all over the body in last month	0.0	0.0	0.1	-0.3	0.0
Illnesses of siblings	0.0	0.0	0.1	-0.1	0.2
Happiness	0.0	0.0	0.0	0.2	0.2
Hair/balding pattern: Pattern 4	0.0	0.0	0.0	0.1	0.0
Headache pain in last month	0.0	0.1	0.1	-0.1	-0.4
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.0	0.2	0.0
Comparative body size at age 10	0.0	0.0	0.0	-0.2	0.0
Pulse wave peak to peak time	0.0	0.0	0.1	0.2	0.2
Mean time to correctly identify matches	0.0	0.0	0.1	0.1	-0.2
Age at last live birth	0.0	0.0	0.0	0.1	0.2
Hypertension (Self-reported)	0.0	0.0	0.0	-0.1	-0.1
Mood swings	0.0	0.0	0.1	-0.3	0.1
Arm fat mass (left)	0.0	0.2	0.3	0.3	0.6
Guilty feelings	0.0	0.1	0.1	-0.0	0.4
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.0	0.1	0.0
Medication: Lisinopril	0.0	0.0	0.1	0.0	0.3

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