TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Trunk fat-free mass
:
←
→
chr14:103,161,201-104,699,495
Best TWAS P=1.12e-12 · Best GWAS P=1.48e-11 conditioned to 0.557
103.2M
103.4M
103.6M
103.8M
104M
104.2M
104.4M
104.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Mucosa
MARK3
0.11
0.03
lasso
4
0.04
1.5e-03
6.7
7.1
1.1e-12
0.91
0.04
0.82
TRUE
2
GTEx
Thyroid
TRMT61A
0.11
0.03
lasso
4
0.02
1.2e-02
6.7
-6.4
1.9e-10
-0.95
0.01
0.98
FALSE
3
YFS
Blood
MARK3
0.04
0.04
lasso
3
0.04
1.6e-12
6.4
6.3
2.5e-10
0.87
0.07
0.93
FALSE
4
The Cancer Genome Atlas
Thyroid Carcinoma
MARK3
0.10
0.03
blup
61
0.03
4.0e-04
-4.5
-5.3
1.2e-07
-0.53
0.03
0.14
FALSE