TWAS hub - MARK3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1200	0.0420	5.7e-05	0.049	NA	0.022	NA	0.055	7.5e-05	NA	6.2e-03	NA	2.5e-05
2	GTEx	Breast Mammary Tissue	0.1240	0.0480	1.4e-03	0.108	NA	0.057	NA	0.085	3.6e-06	NA	6.6e-04	NA	3.9e-05
3	GTEx	Breast Mammary Tissue (Male)	0.0786	0.0702	1.3e-01	0.002	NA	-0.011	NA	-0.013	2.8e-01	NA	7.2e-01	NA	9.1e-01
4	GTEx	Breast Mammary Tissue (Female)	0.0411	0.0515	2.6e-01	-0.010	NA	-0.010	NA	-0.010	9.1e-01	NA	8.9e-01	NA	9.4e-01
5	GTEx	Esophagus Mucosa	0.1120	0.0450	4.6e-03	0.026	NA	-0.001	NA	0.037	7.5e-03	NA	3.6e-01	NA	1.5e-03
6	GTEx	Lung	0.0645	0.0265	1.6e-03	0.023	NA	0.000	NA	0.009	7.1e-03	NA	3.2e-01	NA	6.6e-02
7	GTEx	Pituitary	0.2050	0.0730	4.5e-04	0.274	NA	0.252	NA	0.237	1.4e-07	NA	4.9e-07	NA	1.2e-06
8	GTEx	Prostate	0.1820	0.0690	1.5e-03	0.216	NA	0.203	NA	0.177	3.8e-06	NA	8.0e-06	NA	3.3e-05
9	GTEx	Skin Not Sun Exposed Suprapubic	0.1610	0.0520	5.8e-05	0.104	NA	0.040	NA	0.095	2.5e-06	NA	3.1e-03	NA	6.7e-06
10	GTEx	Skin Sun Exposed Lower leg	0.0960	0.0320	1.3e-05	0.089	NA	0.076	NA	0.066	8.3e-08	NA	7.5e-07	NA	4.0e-06
11	GTEx	Stomach	0.1010	0.0460	6.2e-03	0.092	NA	0.029	NA	0.042	3.5e-05	NA	1.6e-02	NA	4.5e-03
12	GTEx	Thyroid	0.3850	0.0500	0.0e+00	0.484	NA	0.461	NA	0.481	1.4e-41	NA	5.8e-39	NA	2.8e-41
13	METSIM	Adipose	0.0316	0.0126	7.3e-05	0.025	0.018	0.021	0.016	0.026	1.1e-04	9.6e-04	3.8e-04	1.3e-03	6.3e-05
14	YFS	Blood	0.0442	0.0151	6.6e-07	0.041	0.024	0.035	0.034	0.038	2.9e-13	1.7e-08	9.6e-12	2.4e-11	1.6e-12
15	TCGA	Glioblastoma Multiforme	0.1250	0.0710	6.2e-03	0.052	0.072	-0.004	NA	0.005	1.1e-02	3.3e-03	4.6e-01	NA	2.2e-01
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.0672	0.0287	1.4e-06	0.029	0.057	0.052	NA	0.050	3.1e-04	5.5e-07	1.7e-06	NA	2.7e-06
17	TCGA	Prostate Adenocarcinoma	0.0677	0.0298	6.8e-07	0.056	0.067	0.080	NA	0.079	1.7e-06	1.6e-07	1.0e-08	NA	1.2e-08
18	TCGA	Thyroid Carcinoma	0.1040	0.0720	3.4e-03	0.027	0.032	0.019	NA	0.022	1.0e-03	4.0e-04	4.9e-03	NA	3.1e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Heel T-Score	43.6	346.4	497.3	-21.0	-22.0	-20.0	0.7	-21.0	-21.7	-21.6	-21.1	-21.5	-22.3	-22.1	-14.3	8.1	-21.9	-18.0	-19.2	-14.0
Heel bone mineral density (BMD) T-score, automated (left)	24.3	55.0	77.3	-8.4	-8.7	-7.7	1.5	-8.6	-8.6	-8.5	-8.5	-8.4	-8.8	-8.7	-5.6	4.1	-8.5	-6.9	-7.8	-6.0
Heel bone mineral density (BMD) T-score, automated (right)	20.8	47.7	69.4	-8.0	-8.3	-7.4	1.0	-7.9	-8.1	-8.1	-8.0	-7.9	-8.3	-8.3	-4.6	3.0	-8.3	-6.2	-6.9	-5.2
Maternal smoking around birth	10.5	15.2	24.2	-3.7	-4.4	-3.1	-1.3	-4.7	-4.7	-4.8	-4.0	-4.3	-4.5	-4.4	-4.9	0.6	-4.5	-4.3	-4.2	-2.4
Crohns Disease (2017)	8.4	18.3	25.6	-4.9	-5.0	-4.4	1.1	-4.8	-5.0	-4.9	-5.1	-4.8	-5.0	-5.0	-2.9	2.8	-4.6	-4.1	-4.7	-3.9
BMI	7.8	45.3	62.7	-6.6	-7.6	-7.4	-2.0	-7.8	-7.9	-7.7	-7.0	-7.8	-7.7	-7.6	-7.5	1.8	-7.3	-7.3	-7.1	-5.2
Hearing difficulty/problems with background noise	7.7	12.4	31.1	-2.1	-3.5	-3.2	-3.2	-3.8	-3.7	-3.9	-2.7	-4.3	-3.6	-3.6	-5.6	-1.4	-3.5	-4.9	-4.0	-2.4
Medication: Metformin	7.3	10.2	16.2	-3.6	-3.5	-4.0	0.7	-3.5	-3.4	-3.3	-3.5	-3.8	-3.5	-3.5	-2.4	1.7	-3.3	-3.3	-3.8	-3.3
Pack years of smoking	7.1	10.4	16.3	-3.0	-3.5	-3.9	-0.6	-3.7	-3.7	-3.6	-3.3	-4.0	-3.6	-3.5	-4.0	1.5	-3.4	-3.4	-3.3	-2.2
Body mass index (BMI)	6.8	28.8	42.5	-5.3	-6.1	-5.7	-1.4	-6.2	-6.4	-6.2	-5.7	-6.5	-6.1	-6.1	-5.9	1.4	-6.0	-5.7	-5.5	-4.1
Diabetes (self-reported)	6.8	10.6	14.8	-3.6	-3.7	-3.7	0.1	-3.6	-3.6	-3.5	-3.6	-3.9	-3.6	-3.7	-3.1	1.2	-3.7	-3.2	-3.6	-3.1
Diabetes diagnosed by doctor	6.7	10.9	15.9	-3.5	-3.8	-4.0	0.2	-3.6	-3.7	-3.7	-3.6	-3.8	-3.7	-3.8	-3.3	1.5	-3.8	-3.0	-3.4	-3.1
High blood pressure (siblings)	6.6	9.5	20.2	-2.7	-3.6	-3.6	-2.5	-3.3	-3.8	-3.8	-3.2	-3.3	-3.9	-3.6	-2.9	-0.1	-4.5	-3.0	-1.9	-0.2
Impedance of leg (right)	6.5	31.5	46.3	5.9	6.0	6.7	-1.5	6.5	6.3	6.0	6.2	5.9	6.0	6.0	4.8	-4.0	5.2	5.9	6.8	6.2
Type 2 Diabetes (T2D) (2018)	6.4	12.1	18.1	-3.7	-4.2	-4.0	-0.0	-3.6	-4.0	-3.9	-4.0	-4.0	-4.1	-4.2	-3.2	1.5	-4.3	-3.1	-3.3	-2.8
Angina (self-reported)	6.3	8.3	18.7	-1.8	-2.9	-2.1	-2.8	-3.0	-3.0	-3.0	-2.1	-3.7	-3.1	-3.0	-3.6	-1.9	-3.8	-4.3	-3.0	-1.3
Angina	6.2	8.1	18.1	-1.8	-2.9	-2.1	-2.7	-3.0	-3.0	-3.0	-2.1	-3.7	-3.0	-2.9	-3.7	-1.8	-3.7	-4.3	-3.0	-1.4
Mouth/teeth dental problems	6.2	9.6	28.2	2.2	3.0	2.1	2.7	3.6	3.4	3.4	2.3	3.8	3.1	3.0	5.3	0.8	3.1	4.4	3.6	1.6
Supplements: Fish oil (including cod liver oil)	6.2	8.0	13.0	2.5	3.1	3.0	1.1	3.2	3.3	3.4	2.5	3.6	3.1	3.1	3.3	0.3	3.1	3.6	3.3	1.8
Pack years adult smoking proportion	6.0	9.2	16.1	-2.7	-3.3	-4.0	-0.7	-3.4	-3.5	-3.4	-3.1	-3.7	-3.4	-3.4	-3.9	1.3	-3.3	-3.0	-2.8	-1.9
Body Mass Index (BMI) (2010)	5.9	8.0	13.1	-3.6	-3.2	-3.1	1.9	-3.2	-3.3	-3.2	-3.4	-3.1	-3.2	-3.2	-0.9	3.0	-3.1	-1.7	-2.6	-2.6
Irritable Bowel Disease (IBD)	5.7	13.6	19.5	-4.0	-4.3	-3.5	0.2	-4.2	-4.4	-4.3	-4.2	-4.2	-4.4	-4.4	-2.6	2.0	-4.2	-3.8	-4.0	-3.3
Supplements: Calcium	5.7	6.3	9.2	3.0	3.0	2.5	-1.1	2.8	2.9	3.0	3.0	2.5	2.9	3.0	1.3	-2.0	2.8	1.9	2.4	2.6
Intelligence (Savage-Jansen 2018)	5.6	17.1	30.3	5.5	4.3	3.2	-5.1	4.3	4.0	3.6	4.9	3.9	4.2	4.4	-1.2	-5.4	3.4	3.0	5.1	4.6
Smoking Status	5.6	13.4	19.6	-3.5	-4.2	-4.3	-1.5	-3.9	-4.2	-4.3	-4.0	-4.4	-4.2	-4.2	-4.1	1.5	-4.3	-3.3	-3.2	-3.1
Lung cancer (father)	5.6	6.5	13.1	-1.9	-2.7	-1.8	-2.0	-3.1	-2.7	-2.8	-2.2	-3.6	-2.7	-2.7	-3.3	-0.4	-2.9	-3.2	-2.5	-2.5
Gout (self-reported)	5.6	7.7	13.8	-3.0	-2.9	-3.7	0.6	-3.0	-3.1	-3.2	-3.2	-3.2	-3.0	-2.9	-2.3	2.3	-2.8	-2.6	-3.1	-2.4
Illnesses of father: High blood pressure	5.6	7.0	11.3	-2.9	-3.1	-2.7	-0.3	-3.1	-3.1	-3.2	-2.6	-2.7	-3.3	-3.1	-2.5	-0.4	-3.4	-3.0	-2.9	-0.2
Major Depression (MDD)	5.5	6.6	16.6	3.6	2.5	1.2	-4.0	2.6	2.4	2.4	3.2	2.0	2.1	2.4	-1.4	-4.1	1.6	1.0	2.7	3.2
Arm fat percentage (left)	5.5	22.1	36.0	-4.1	-5.2	-4.7	-2.6	-5.3	-5.5	-5.4	-4.6	-5.9	-5.3	-5.2	-6.0	-0.0	-5.1	-5.5	-4.9	-3.2
Arm fat percentage (right)	5.4	21.4	37.3	-4.0	-5.1	-4.6	-2.9	-5.2	-5.4	-5.3	-4.5	-5.8	-5.2	-5.1	-6.1	-0.2	-5.1	-5.3	-4.7	-3.1
Wheeze or whistling in the chest in last year	5.4	9.5	16.6	-3.0	-3.4	-2.4	-0.5	-3.6	-3.5	-3.4	-3.0	-3.7	-3.5	-3.4	-3.4	0.7	-3.8	-4.1	-3.6	-2.0
Impedance of leg (left)	5.3	25.5	39.5	5.1	5.3	6.2	-1.1	5.8	5.5	5.2	5.4	5.4	5.3	5.3	4.7	-3.6	4.6	5.5	6.3	5.7
Number of self-reported non-cancer illnesses	5.2	9.1	16.9	-2.7	-3.1	-2.1	-2.2	-3.2	-3.4	-3.6	-2.8	-4.1	-3.2	-3.1	-3.8	-0.1	-3.8	-3.7	-3.0	-2.3
Overall health rating	5.0	10.8	25.5	-2.7	-3.2	-2.9	-1.9	-3.9	-3.5	-3.2	-2.8	-4.0	-3.3	-3.2	-5.0	0.2	-3.4	-4.6	-4.0	-2.5
Mineral and other dietary supplements	5.0	6.8	10.9	-2.2	-3.0	-2.7	-1.3	-2.9	-3.0	-3.1	-2.4	-3.1	-3.0	-3.0	-3.3	-0.3	-2.9	-3.3	-2.7	-1.1
Arm fat mass (left)	5.0	20.7	29.9	-4.5	-4.9	-4.7	-0.3	-5.3	-5.2	-5.1	-4.8	-5.5	-4.9	-4.9	-5.2	1.8	-4.4	-5.0	-5.4	-4.5
Cardiovascular Disease	4.9	16.3	32.5	-3.8	-4.7	-4.4	-2.9	-4.2	-4.9	-4.9	-4.0	-4.9	-4.9	-4.7	-4.3	-0.2	-5.7	-3.9	-2.8	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	4.9	6.3	19.5	3.8	2.3	1.5	-4.4	2.2	2.3	2.3	2.9	1.6	2.2	2.3	-1.8	-4.2	1.6	0.0	2.2	2.6
Medication: Blood pressure	4.9	9.4	15.8	-3.2	-3.7	-3.8	-1.4	-3.2	-3.7	-3.7	-3.2	-3.7	-3.6	-3.7	-2.2	0.4	-4.0	-2.8	-2.6	-2.4
Neuroticism (2016)	4.8	6.9	10.9	3.0	3.1	2.5	-1.6	3.3	3.2	3.2	3.2	2.2	3.0	3.0	1.5	-2.7	2.2	2.1	2.8	2.2
Arm fat mass (right)	4.8	19.7	28.0	-4.4	-4.8	-4.6	-0.3	-5.2	-5.1	-5.0	-4.7	-5.3	-4.8	-4.8	-5.1	1.7	-4.4	-4.8	-5.1	-4.2
Osteoporosis (self-reported)	4.8	6.0	10.1	3.1	3.0	3.1	-0.8	2.7	3.0	2.9	2.9	2.4	3.0	2.9	1.1	-1.7	3.2	1.8	1.9	1.0
Impedance of whole body	4.8	24.6	34.0	5.6	5.5	5.8	-2.1	5.7	5.6	5.3	5.7	5.3	5.4	5.4	3.4	-4.3	4.9	4.5	5.5	5.3
Past tobacco smoking	4.7	8.6	13.3	2.8	3.4	2.8	1.4	3.2	3.4	3.6	3.2	3.3	3.4	3.3	3.3	-1.0	3.2	3.2	3.0	2.4
Crohns Disease (2012)	4.5	7.3	10.5	-3.1	-3.0	-2.7	1.3	-2.8	-3.0	-2.9	-3.2	-3.0	-2.9	-3.0	-2.1	2.2	-2.5	-2.5	-3.2	-3.0
Multivitamins +/- minerals	4.4	5.6	10.6	2.5	2.5	1.9	-1.1	2.7	2.5	2.6	2.6	2.6	2.4	2.5	1.8	-1.8	1.9	2.7	3.3	2.9
Fractured/broken bones in last 5 years	4.4	5.7	9.2	2.8	3.0	2.5	-0.4	2.4	2.7	2.8	2.8	2.9	2.9	3.0	1.8	-1.0	3.0	1.5	1.9	2.5
Vascular/heart problems diagnosed by doctor	4.4	11.9	26.5	3.2	3.9	3.7	3.1	3.4	4.1	4.0	3.3	4.5	4.0	3.9	3.6	0.9	5.2	3.4	2.3	1.2
Verbal and Numeric Reasoning (VNR)	4.2	10.1	17.9	4.1	3.3	2.4	-4.1	3.3	3.0	2.6	3.8	2.7	3.1	3.3	-0.4	-4.2	2.6	2.4	4.0	4.1
Waist circumference	4.1	14.9	21.6	-4.0	-4.1	-3.9	0.5	-4.5	-4.4	-4.2	-4.2	-4.6	-4.1	-4.1	-4.5	2.1	-3.6	-4.0	-4.6	-3.9
Leg fat mass (left)	4.1	15.9	24.1	-4.3	-4.4	-3.9	0.3	-4.7	-4.7	-4.5	-4.4	-4.9	-4.5	-4.4	-4.0	1.9	-4.1	-4.1	-4.4	-3.6
Supplements: Zinc	4.0	4.3	7.1	2.5	2.2	2.0	-1.0	2.3	2.3	2.2	2.5	2.0	2.2	2.2	1.6	-2.2	2.0	2.3	2.7	2.0
Impedance of arm (right)	3.9	18.3	27.2	5.2	4.8	4.9	-2.3	4.9	5.0	4.6	5.1	4.6	4.7	4.8	1.9	-4.3	4.5	3.1	4.1	4.1
Vitamin and mineral supplements	3.8	5.1	8.3	-2.4	-2.6	-1.8	0.2	-2.5	-2.5	-2.6	-2.4	-2.7	-2.6	-2.6	-2.1	1.0	-2.3	-2.8	-2.9	-1.9
Bipolar Disorder or Schizophrenia	3.7	9.0	37.5	-0.9	-2.5	-2.5	-4.2	-2.9	-2.9	-3.0	-1.8	-3.5	-2.8	-2.6	-6.1	-2.1	-3.3	-3.6	-2.5	-2.0
Leg fat percentage (left)	3.7	13.4	23.4	-3.5	-4.2	-3.2	-2.0	-4.2	-4.5	-4.4	-3.8	-4.8	-4.3	-4.3	-4.1	-0.1	-4.5	-3.9	-3.3	-1.7
High blood pressure	3.6	10.1	23.5	-3.2	-3.7	-3.5	-2.3	-3.2	-3.8	-3.8	-3.3	-4.1	-3.8	-3.7	-2.9	-0.1	-4.8	-2.8	-2.0	-1.2
Body fat percentage	3.6	14.2	24.0	-3.6	-4.2	-3.4	-1.8	-4.2	-4.5	-4.4	-3.9	-4.9	-4.3	-4.2	-4.6	0.1	-4.3	-4.3	-3.8	-2.2
Whole body fat mass	3.6	14.9	22.1	-4.1	-4.2	-3.7	0.4	-4.4	-4.4	-4.3	-4.2	-4.7	-4.2	-4.2	-4.1	1.9	-3.7	-4.2	-4.6	-3.8
Risk taking	3.6	5.3	18.7	-1.2	-1.9	-1.7	-2.6	-2.2	-2.1	-2.2	-1.4	-2.8	-2.0	-1.9	-4.3	-1.7	-2.3	-3.5	-2.7	-1.6
Schizophrenia (2014)	3.5	7.7	34.1	-1.0	-2.3	-2.3	-3.2	-2.8	-2.7	-2.8	-1.7	-3.4	-2.8	-2.4	-5.8	-1.3	-3.2	-3.4	-2.3	-1.8
Smoking status: Previous	3.5	5.2	8.0	-2.5	-2.7	-1.9	-0.5	-2.4	-2.6	-2.8	-2.7	-2.5	-2.7	-2.7	-1.6	1.2	-2.6	-2.3	-2.4	-2.2
Illnesses of father: None of the above (group 1)	3.5	4.3	7.2	2.7	2.5	2.3	-1.7	2.4	2.3	2.2	2.4	2.0	2.5	2.5	1.1	-1.3	1.8	1.7	2.7	1.4
Irritability	3.5	5.9	16.5	3.6	2.5	1.7	-4.1	2.4	2.7	2.4	3.0	1.8	2.4	2.5	-1.2	-3.4	2.3	0.1	1.7	1.8
Medication: Paracetamol	3.4	5.6	13.3	-1.4	-2.3	-2.6	-2.3	-2.8	-2.7	-2.5	-1.8	-2.7	-2.4	-2.3	-3.6	-0.6	-2.4	-3.5	-2.7	-1.0
Alzheimer’s Disease (including proxy)	3.3	4.7	8.2	-2.8	-2.7	-1.5	0.3	-2.4	-2.9	-2.8	-2.7	-2.0	-2.6	-2.7	-0.9	1.3	-2.8	-1.8	-1.9	-1.7
Height	3.3	63.9	174.2	4.2	8.6	7.5	13.2	7.8	8.7	8.8	5.7	8.9	8.8	8.6	9.8	7.2	10.9	8.4	3.5	-1.5
Illnesses of siblings	3.3	4.6	9.1	1.9	2.5	2.2	2.0	2.4	2.8	2.9	2.2	2.2	2.8	2.6	1.9	0.3	3.0	1.8	0.9	-1.0
Leg fat mass (right)	3.3	12.8	20.0	-3.8	-4.0	-3.5	0.2	-4.1	-4.2	-4.0	-3.9	-4.5	-4.0	-4.0	-3.7	1.6	-3.7	-3.7	-4.0	-3.2
Hypertension (Self-reported)	3.3	9.1	20.7	-2.9	-3.5	-3.3	-2.5	-3.1	-3.6	-3.6	-3.1	-3.9	-3.6	-3.5	-2.9	-0.2	-4.6	-2.7	-1.9	-1.1
Mother’s age at death	3.3	4.2	9.7	1.6	2.3	2.1	1.2	2.4	2.6	2.6	2.1	2.2	2.4	2.3	3.1	0.1	2.4	1.9	1.5	1.2
Schizophrenia (2018)	3.2	6.6	27.7	-0.9	-2.1	-2.2	-3.1	-2.5	-2.5	-2.6	-1.5	-3.1	-2.5	-2.2	-5.3	-1.5	-3.0	-3.1	-2.2	-1.5
Blood Eosinophil Count	3.2	24.4	37.8	-4.9	-5.7	-5.4	-2.4	-5.5	-5.9	-5.9	-5.3	-6.1	-5.6	-5.7	-4.2	1.4	-6.1	-3.8	-3.8	-5.7
Financial difficulties in last 2 years	3.2	4.4	13.4	-1.4	-2.1	-2.8	-1.9	-2.3	-2.5	-2.3	-1.9	-2.4	-2.2	-2.1	-3.7	-0.0	-2.3	-1.6	-1.3	-1.4
Mouth/teeth dental problems: Dentures	3.2	5.3	8.7	-2.6	-2.5	-1.4	0.3	-3.0	-2.8	-2.6	-2.6	-2.9	-2.6	-2.5	-2.5	1.5	-2.6	-2.5	-2.6	-1.2
Impedance of arm (left)	3.2	14.8	21.1	4.6	4.3	4.4	-2.1	4.4	4.5	4.2	4.6	4.1	4.3	4.3	2.0	-3.9	4.0	2.8	3.7	3.8
Medication: Allopurinol	3.2	4.2	7.5	-2.0	-2.0	-2.7	-0.3	-2.3	-2.3	-2.2	-2.0	-2.6	-2.0	-2.0	-2.1	1.0	-1.9	-2.2	-2.6	-2.2
Pulse rate, automated reading	3.2	10.3	14.7	-3.5	-3.6	-3.0	0.2	-3.7	-3.8	-3.8	-3.8	-3.8	-3.6	-3.6	-3.1	2.7	-3.2	-2.4	-2.9	-3.4
Average weekly spirits intake	3.1	3.9	8.6	-2.4	-1.8	-1.5	1.2	-2.5	-2.2	-2.3	-1.9	-2.3	-1.9	-1.8	-1.3	0.9	-1.8	-2.5	-2.9	-1.9
Chronic bronchitis/emphysema (father)	3.1	3.6	5.9	-2.3	-2.4	-1.7	0.6	-2.1	-2.3	-2.3	-2.2	-2.0	-2.4	-2.4	-1.1	0.9	-2.1	-1.1	-1.8	-2.1
Nervous feelings	3.1	5.8	9.7	2.9	2.9	2.7	-0.5	2.7	3.0	3.1	3.0	2.2	2.9	2.9	1.4	-1.7	2.6	1.3	1.9	2.4
Medication: Simvastatin	3.1	4.5	11.0	-2.2	-2.4	-3.3	-0.9	-2.2	-2.5	-2.3	-2.3	-2.5	-2.4	-2.4	-1.5	0.6	-2.6	-2.3	-1.9	-1.0
Comparative height size at age 10	3.1	17.1	52.8	1.6	4.3	3.2	7.3	3.7	4.2	4.3	2.8	5.0	4.5	4.3	5.7	3.8	5.6	4.4	1.5	-0.9
Supplements: Glucosamine	3.0	3.9	8.0	1.1	2.1	1.9	2.4	1.9	2.1	2.1	1.3	2.7	2.2	2.1	2.4	1.8	2.8	2.4	1.3	0.3
Heart attack	3.0	3.9	7.4	-1.4	-2.0	-2.0	-2.1	-2.2	-2.2	-2.2	-1.5	-2.3	-2.1	-2.0	-2.7	-1.1	-2.4	-2.6	-1.7	-0.5
Qualifications: College or University degree	3.0	9.5	22.1	4.7	3.2	2.0	-4.2	3.1	3.2	3.1	3.7	2.8	3.0	3.2	-2.0	-4.4	3.0	0.9	2.7	2.3
Leg predicted mass (right)	3.0	15.9	42.2	-4.5	-3.3	-4.3	5.2	-4.0	-3.5	-3.3	-4.3	-3.2	-3.1	-3.3	-2.0	5.7	-1.8	-3.1	-5.4	-6.5
Financial situation satisfaction	3.0	3.7	6.6	-1.5	-1.8	-2.6	-0.7	-2.2	-1.9	-1.6	-1.7	-2.5	-1.9	-1.8	-2.3	0.8	-1.7	-2.3	-2.5	-2.3
Trunk fat mass	2.9	12.4	19.5	-3.7	-3.7	-3.4	0.7	-4.0	-3.9	-3.8	-3.9	-4.2	-3.8	-3.8	-3.8	1.9	-3.2	-3.9	-4.4	-3.5
Emphysema/chronic bronchitis	2.9	3.3	6.4	-1.5	-1.8	-2.2	-1.7	-2.0	-2.1	-2.1	-1.6	-1.6	-1.9	-1.9	-2.5	-0.2	-2.3	-2.3	-1.5	-1.1
Leg fat-free mass (right)	2.9	15.5	41.4	-4.4	-3.2	-4.3	5.3	-3.9	-3.5	-3.2	-4.2	-3.1	-3.1	-3.2	-1.9	5.7	-1.7	-3.0	-5.3	-6.4
Blood Platelet Count	2.8	32.6	50.3	-6.8	-6.7	-5.1	3.0	-6.6	-6.5	-6.1	-7.1	-6.7	-6.8	-6.7	-2.4	6.2	-6.0	-4.6	-5.8	-4.0
Ever used hormone-replacement therapy (HRT)	2.8	3.6	13.4	-2.6	-1.5	-1.9	3.2	-1.6	-1.6	-1.7	-2.1	-0.9	-1.4	-1.5	0.5	3.7	-1.2	-0.3	-1.7	-2.4
Trunk fat percentage	2.8	11.2	18.7	-3.1	-3.7	-3.0	-1.4	-3.7	-3.9	-3.8	-3.4	-4.3	-3.8	-3.7	-4.3	0.2	-3.6	-4.0	-3.7	-2.3
Serious illness, injury or assault to yourself	2.8	3.4	8.9	-1.2	-1.9	-1.5	-1.4	-2.1	-2.0	-2.2	-1.4	-2.0	-2.0	-1.9	-3.0	-0.6	-1.9	-2.3	-1.9	-1.6
Depression (self-reported)	2.8	3.4	6.0	2.2	2.0	2.5	-2.1	2.2	1.9	1.8	1.9	2.0	2.0	2.0	0.1	-1.5	1.7	1.3	2.1	1.8
Medication: Paracetamol	2.8	4.3	10.1	-1.2	-2.1	-2.1	-2.1	-2.3	-2.3	-2.2	-1.6	-2.3	-2.1	-2.0	-3.2	-0.4	-1.9	-3.2	-2.4	-0.8
Diastolic blood pressure, automated reading	2.8	8.6	14.7	-3.2	-3.5	-3.1	-1.1	-3.1	-3.7	-3.7	-3.6	-3.5	-3.5	-3.5	-3.2	1.6	-3.8	-1.6	-1.6	-1.6
Taking other prescription medications	2.7	4.1	7.0	-1.8	-2.1	-2.0	-1.1	-2.2	-2.2	-2.2	-1.9	-2.6	-2.2	-2.1	-2.6	0.2	-2.2	-2.6	-2.4	-1.6
Weight	2.7	13.3	25.5	-4.1	-3.5	-3.8	3.1	-4.0	-3.7	-3.5	-4.0	-3.7	-3.4	-3.5	-3.0	3.8	-2.5	-3.4	-4.9	-5.0
Leg fat percentage (right)	2.7	9.7	18.2	-2.8	-3.6	-2.7	-2.3	-3.5	-3.7	-3.6	-3.1	-4.3	-3.7	-3.6	-3.7	-0.6	-3.8	-3.3	-2.6	-1.2
Pulse wave peak to peak time	2.7	3.2	4.9	1.7	2.0	2.0	0.3	2.0	2.0	2.0	1.8	2.0	2.0	2.0	1.6	-0.4	1.7	2.0	2.2	1.9
Health satisfaction	2.7	3.5	10.5	-1.5	-1.9	-1.9	-0.4	-2.2	-2.0	-1.7	-1.7	-2.4	-2.0	-1.9	-3.2	0.7	-2.1	-2.2	-2.1	-1.3
Heart attack/myocardial infarction (self-reported)	2.7	3.5	6.6	-1.3	-1.9	-1.8	-2.1	-2.1	-2.0	-2.1	-1.4	-2.3	-2.0	-1.9	-2.6	-1.2	-2.3	-2.6	-1.7	-0.5
Leg fat-free mass (left)	2.6	14.0	37.1	-4.2	-3.1	-4.1	4.9	-3.8	-3.3	-3.0	-4.0	-3.0	-2.9	-3.1	-2.1	5.4	-1.6	-2.9	-5.1	-6.1
Qualifications: O levels/GCSEs or equivalent	2.6	4.1	7.3	1.9	2.4	2.3	-0.4	2.3	2.0	1.9	2.2	2.3	2.5	2.4	1.4	-0.7	2.3	2.7	2.7	1.1
Commuting to job workplace: Walk	2.6	2.8	7.4	1.7	1.8	1.4	-0.8	2.0	1.8	1.7	1.6	1.7	1.7	1.8	1.1	-0.9	1.2	1.8	2.6	2.7
Leg predicted mass (left)	2.5	13.4	36.7	-4.1	-3.0	-4.0	4.9	-3.6	-3.2	-2.9	-3.9	-2.9	-2.8	-2.9	-1.9	5.4	-1.5	-2.8	-5.0	-6.1
Fluid intelligence score	2.5	5.2	12.7	3.2	2.2	1.3	-3.6	2.0	2.0	1.7	2.5	1.9	1.9	2.1	-1.5	-3.4	1.6	1.4	2.9	3.0
Supplements: Vitamin C	2.5	3.0	7.2	1.4	1.9	1.3	0.8	1.9	2.0	2.0	1.5	2.1	1.9	1.9	2.7	0.1	1.8	2.4	2.0	0.9
Long-standing illness, disability or infirmity	2.5	3.8	19.9	-0.5	-1.7	-1.6	-2.6	-1.9	-1.8	-1.6	-1.2	-1.9	-1.9	-1.7	-4.5	-1.3	-1.7	-2.5	-1.9	-1.1
Medication for cholesterol	2.5	3.8	5.9	2.1	2.3	2.4	0.5	2.1	2.3	2.3	2.1	2.4	2.2	2.3	1.5	-0.8	2.2	1.8	1.9	1.8
Smoking status: Current	2.5	3.9	10.7	-1.6	-2.1	-2.4	-0.8	-2.2	-2.2	-2.3	-1.9	-2.3	-2.1	-2.1	-3.3	0.9	-2.0	-2.0	-1.8	-1.2
Ever smoked	2.5	4.4	6.5	-1.9	-2.3	-2.0	-1.0	-2.1	-2.4	-2.6	-2.4	-2.2	-2.4	-2.3	-2.5	1.1	-2.1	-2.4	-2.1	-1.9
Hearing difficulty/problems: Yes	2.4	3.7	8.6	-1.4	-1.9	-1.6	-1.0	-2.0	-2.0	-2.2	-1.7	-2.4	-1.9	-1.9	-2.9	0.4	-1.7	-2.2	-2.2	-2.6
Fed-up feelings	2.4	4.4	9.7	2.8	2.2	1.7	-2.0	2.2	2.2	2.0	2.3	2.3	2.1	2.2	0.2	-1.6	1.6	1.7	2.9	3.1
Had menopause	2.4	3.0	5.5	-2.2	-1.8	-1.0	1.6	-1.9	-1.8	-1.9	-2.0	-1.9	-1.7	-1.8	-1.0	1.8	-1.2	-1.5	-2.4	-2.1
Standing height	2.4	23.8	91.7	2.0	5.0	3.5	9.6	4.2	5.1	5.2	3.0	5.4	5.3	5.0	5.5	5.3	7.0	4.4	0.6	-2.7
Medication for pain relief, constipation, heartburn	2.4	4.1	9.5	1.3	2.1	1.9	2.1	2.3	2.3	2.1	1.8	2.2	2.1	2.1	3.1	0.4	2.4	2.9	2.0	0.2
Forced expiratory volume in 1-second (FEV1), predicted	2.4	5.0	10.8	1.7	2.6	1.9	2.6	2.4	2.7	2.8	2.0	2.7	2.6	2.6	2.3	1.4	3.3	2.3	1.3	0.4
Mean Putamen Volume	2.3	2.6	4.4	1.7	1.7	2.1	-0.5	2.0	1.8	1.7	1.7	1.7	1.8	1.7	1.1	-1.0	1.5	2.0	1.9	1.7
Breastfed as a baby	2.3	2.8	5.7	1.3	1.8	2.4	1.4	1.9	1.9	1.8	1.4	2.2	1.9	1.8	1.7	0.6	2.1	2.2	1.5	-0.3
Medication for cholesterol, blood pressure or diabetes	2.3	3.7	7.4	2.0	2.2	1.8	1.1	2.1	2.4	2.4	2.0	2.3	2.4	2.2	1.9	-0.2	2.7	2.0	1.6	0.9
Ever unenthusiastic/disinterested for a whole week	2.2	2.7	8.8	2.2	1.4	1.6	-2.9	1.3	1.4	1.3	1.9	1.0	1.3	1.4	-1.4	-3.0	1.2	-0.3	0.9	2.0
Noisy workplace	2.2	2.7	6.8	-1.6	-1.6	-0.6	0.2	-2.1	-1.7	-1.7	-1.5	-2.1	-1.5	-1.6	-2.4	0.1	-1.3	-2.3	-2.6	-1.5
Qualifications: A levels/AS levels or equivalent	2.2	4.8	11.0	3.3	2.2	1.1	-3.2	2.4	2.2	1.9	2.7	2.1	2.0	2.2	-0.6	-3.3	1.7	1.2	2.5	1.8
Pulse wave reflection index	2.2	2.7	4.4	-1.6	-2.0	-1.6	-0.8	-2.0	-2.0	-2.1	-1.6	-1.8	-2.0	-2.0	-0.6	-0.1	-2.1	-1.8	-1.7	-1.1
Mouth/teeth dental problems: Bleeding gums	2.2	2.8	8.9	-0.5	-1.3	-1.3	-3.0	-1.3	-1.4	-1.5	-0.7	-1.8	-1.4	-1.3	-2.8	-2.3	-1.5	-2.5	-1.5	-0.5
Glaucoma (self-reported)	2.2	2.6	6.7	0.7	1.6	1.0	2.5	1.6	1.6	1.7	0.8	1.7	1.6	1.6	2.1	1.7	2.1	2.6	1.5	0.4
Unable to work because of sickness or disability	2.2	2.9	10.6	-0.8	-1.5	-1.6	-2.1	-1.6	-1.8	-1.8	-1.2	-1.9	-1.7	-1.5	-3.3	-0.4	-1.5	-2.4	-1.8	-0.6
Cholesterol lowering medication	2.2	3.3	6.2	-2.1	-2.1	-2.5	0.5	-1.8	-2.1	-2.0	-2.3	-2.1	-2.1	-2.1	-0.8	1.5	-2.0	-1.4	-1.6	-1.5
Arm predicted mass (left)	2.2	11.2	34.8	-3.9	-2.5	-3.1	5.7	-3.1	-2.7	-2.4	-3.6	-2.3	-2.3	-2.5	-0.7	5.9	-1.1	-1.6	-4.1	-5.5
Other serious medical condition/disability diagnosed by doctor	2.1	2.7	5.7	-1.2	-1.8	-1.6	-1.1	-1.9	-1.9	-1.8	-1.6	-2.0	-1.8	-1.8	-2.4	-0.3	-1.8	-1.5	-1.5	-2.0
Current tobacco smoking	2.1	3.4	9.3	-1.6	-2.0	-2.3	-0.6	-2.0	-2.2	-2.2	-1.9	-2.1	-2.0	-2.0	-3.1	1.2	-1.8	-1.5	-1.5	-1.1
Pulse rate	2.1	3.5	6.2	-2.4	-2.0	-1.6	1.3	-2.1	-2.2	-2.0	-2.3	-2.1	-1.9	-1.9	-1.1	2.3	-1.7	-0.8	-1.6	-2.5
Basal metabolic rate	2.1	11.7	33.1	-3.9	-2.5	-3.4	5.6	-3.2	-2.7	-2.4	-3.6	-2.3	-2.3	-2.5	-1.1	5.7	-1.1	-2.0	-4.5	-5.8
Neuroticism (Nagel 2018)	2.0	4.8	8.8	3.0	2.7	2.3	-2.0	2.6	2.6	2.4	2.9	2.0	2.4	2.5	0.2	-2.2	2.1	1.0	2.1	1.8
Ulcerative Colitis (UC)	2.0	3.7	6.2	-2.0	-2.3	-1.3	-0.6	-2.3	-2.4	-2.3	-2.0	-2.1	-2.4	-2.4	-1.4	0.6	-2.5	-2.1	-2.0	-1.6
Pulse wave Arterial Stiffness index	2.0	2.3	4.1	-1.6	-1.6	-1.7	0.4	-1.7	-1.6	-1.7	-1.6	-1.6	-1.6	-1.6	-1.1	0.8	-1.3	-1.6	-2.0	-2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.0	15.7	2.4	1.2	1.8	-4.0	1.4	1.3	1.2	1.7	0.7	1.2	1.2	-1.5	-2.7	0.5	0.6	2.1	1.4
Arm fat-free mass (right)	2.0	10.2	43.6	-3.7	-2.0	-2.7	6.6	-2.5	-2.1	-1.8	-3.2	-1.7	-1.8	-1.9	0.3	6.2	-0.6	-1.1	-3.7	-5.2
Medication: Blood pressure	2.0	3.5	9.3	-1.9	-2.3	-1.4	-1.5	-1.9	-2.3	-2.2	-2.1	-2.3	-2.4	-2.3	-1.5	-0.0	-3.0	-1.8	-1.1	-0.0
Arm predicted mass (right)	2.0	10.3	42.1	-3.8	-2.1	-2.9	6.5	-2.7	-2.2	-1.9	-3.3	-1.8	-1.9	-2.0	0.2	6.2	-0.7	-1.1	-3.7	-5.1
Whole body water mass	2.0	11.5	43.2	-3.7	-2.0	-3.2	6.6	-2.8	-2.2	-1.9	-3.3	-1.8	-1.8	-2.0	-0.3	6.4	-0.5	-1.5	-4.3	-6.0
Arm fat-free mass (left)	2.0	10.0	34.1	-3.6	-2.1	-3.1	5.8	-2.7	-2.3	-2.1	-3.3	-1.9	-1.9	-2.1	-0.5	5.8	-0.8	-1.2	-3.7	-5.4
Worry (Nagel 2018)	1.9	4.0	7.6	2.5	2.5	2.1	-1.2	2.3	2.5	2.3	2.8	1.8	2.5	2.5	0.9	-2.0	2.0	0.7	1.6	1.5
Prostate Cancer	1.9	2.6	5.9	-1.1	-1.8	-2.4	-1.3	-1.8	-1.8	-1.8	-1.4	-2.0	-1.8	-1.8	-2.4	0.2	-1.8	-1.5	-1.1	-0.7
Hair Pigment	1.9	53.2	80.6	-6.7	-8.3	-8.1	-3.4	-8.4	-8.6	-8.6	-7.3	-9.0	-8.4	-8.3	-7.9	0.5	-9.0	-8.1	-7.0	-4.3
Pain all over the body in last month	1.9	2.0	3.6	-1.3	-1.5	-1.1	-0.8	-1.6	-1.7	-1.5	-1.2	-1.8	-1.4	-1.5	-1.4	-0.5	-1.9	-1.9	-1.6	-1.4
Forced expiratory volume in 1-second (FEV1)	1.9	6.3	12.9	1.8	2.8	1.4	2.4	2.9	2.9	3.0	2.2	3.2	3.0	2.9	3.2	1.1	3.6	3.0	1.9	0.0
Illnesses of mother	1.9	2.4	4.1	1.2	1.7	1.9	1.4	1.8	1.8	1.8	1.4	1.6	1.9	1.8	2.0	0.4	2.0	1.4	0.9	-0.9
Suffer from ‘nerves’	1.9	3.0	5.8	2.2	2.3	1.8	-0.7	1.6	2.2	2.3	2.4	1.6	2.4	2.3	0.6	-1.3	2.1	0.3	0.7	0.8
Whole body fat-free mass	1.9	10.9	42.9	-3.6	-2.0	-3.1	6.5	-2.6	-2.1	-1.8	-3.2	-1.7	-1.8	-1.9	-0.3	6.2	-0.4	-1.4	-4.2	-5.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.9	2.2	11.9	-1.8	-1.1	-1.3	2.7	-0.9	-0.9	-0.9	-1.8	-0.7	-1.0	-1.1	0.6	3.5	-0.4	0.1	-1.1	-2.1
Age at First Birth	1.8	2.7	7.4	0.9	1.8	1.7	2.7	1.5	1.8	1.9	1.3	2.0	1.9	1.8	2.3	0.9	2.3	1.0	0.2	0.3
Number of incorrect matches in round	1.8	3.0	5.5	-1.8	-2.0	-1.4	0.9	-2.1	-1.7	-1.9	-1.8	-2.0	-2.0	-1.9	-0.7	0.9	-2.2	-2.3	-2.3	-1.0
Medication: Cholesterol lowering	1.8	2.9	5.8	-1.7	-1.9	-1.9	-0.7	-1.9	-2.1	-2.0	-1.7	-1.8	-2.0	-1.9	-1.7	0.2	-2.4	-1.9	-1.5	-0.9
Qualifications: nursing, teaching	1.8	2.8	5.3	2.3	1.8	1.1	-0.6	2.1	2.0	1.6	1.7	2.2	1.7	1.8	0.1	-0.3	2.1	2.2	2.3	0.7
High cholesterol (Self-reported)	1.8	3.2	5.3	-2.0	-2.0	-2.0	0.2	-1.9	-2.1	-2.0	-2.1	-2.3	-2.1	-2.0	-0.9	1.5	-2.2	-1.7	-1.6	-1.3
Bipolar Disorder (2018)	1.7	2.6	10.4	-0.4	-1.4	-1.3	-2.7	-1.5	-1.5	-1.5	-1.0	-1.8	-1.3	-1.3	-3.2	-1.5	-1.6	-2.0	-1.3	-1.3
Depressed Affect (Nagel 2018)	1.7	3.5	7.0	2.6	2.0	1.8	-2.7	1.9	1.9	1.6	2.3	1.6	1.9	2.0	-0.5	-2.2	1.5	1.0	2.1	1.7
Hip circumference	1.7	7.2	16.3	-2.3	-2.5	-3.0	-0.5	-3.1	-2.9	-2.7	-2.5	-3.3	-2.6	-2.5	-4.0	0.8	-2.1	-3.3	-3.6	-2.9
Hair/balding pattern: Pattern 4	1.7	4.1	6.1	-1.9	-2.4	-1.5	-0.7	-2.4	-2.5	-2.4	-2.1	-2.1	-2.3	-2.4	-2.1	0.2	-2.4	-2.1	-2.1	-2.3
Number of full sisters	1.7	2.1	4.2	-1.5	-1.8	-0.6	-0.5	-1.7	-1.9	-1.9	-1.4	-1.8	-1.9	-1.8	-1.6	0.1	-2.0	-1.4	-1.2	0.0
Blood White Count	1.6	12.1	100.6	2.0	-0.9	-1.4	-10.0	-0.8	-1.1	-1.3	1.1	-2.1	-1.2	-0.9	-4.7	-7.4	-2.6	-1.8	1.7	2.8
Hair/balding pattern: Pattern 2	1.6	2.0	4.7	-1.4	-1.3	-2.2	0.0	-1.4	-1.4	-1.4	-1.4	-1.8	-1.5	-1.3	-2.1	0.4	-1.4	-1.6	-1.7	-1.0
Trunk fat-free mass	1.6	9.1	50.7	-3.1	-1.2	-2.4	7.1	-1.9	-1.3	-1.1	-2.6	-0.8	-1.0	-1.2	0.7	6.3	0.3	-0.5	-3.5	-5.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.0	12.5	1.7	2.6	1.0	2.5	2.5	2.7	2.7	1.9	2.8	2.8	2.6	2.4	1.2	3.5	2.3	1.2	-0.2
Trunk predicted mass	1.6	9.0	50.4	-3.0	-1.2	-2.4	7.1	-1.9	-1.3	-1.1	-2.5	-0.8	-0.9	-1.1	0.7	6.3	0.3	-0.5	-3.5	-5.3
Chest pain or discomfort	1.6	2.3	6.2	-0.7	-1.2	-0.8	-2.1	-1.3	-1.4	-1.4	-0.5	-1.5	-1.4	-1.2	-2.1	-2.0	-2.5	-2.3	-1.0	1.3
Medication: Aspirin	1.6	2.2	8.2	-0.1	-1.1	-1.5	-2.9	-1.1	-1.1	-1.0	-0.6	-1.5	-1.2	-1.1	-2.6	-1.8	-1.4	-2.3	-1.1	0.7
Tinnitus: Yes, now most or all of the time	1.6	1.9	7.0	-0.9	-1.0	-1.7	-0.5	-1.5	-1.1	-1.1	-0.7	-1.9	-0.9	-1.0	-1.9	-0.4	-0.7	-1.7	-2.0	-2.6
Medication: Bendroflumethiazide	1.6	2.4	5.7	-1.9	-2.0	-1.7	-0.5	-1.6	-2.0	-1.9	-1.6	-1.8	-2.0	-2.0	-0.1	0.3	-2.4	-1.1	-0.8	-0.7
Fasting Glucose	1.5	1.8	3.6	1.2	1.3	0.6	0.6	1.9	1.5	1.5	1.2	1.6	1.3	1.3	1.3	-0.0	1.4	1.8	1.7	1.8
Ever had hysterectomy (womb removed)	1.5	1.7	3.9	-1.5	-1.5	-0.7	1.2	-1.4	-1.3	-1.4	-1.4	-1.5	-1.5	-1.5	-0.7	1.3	-1.0	-1.3	-2.0	-1.3
Qualifications: CSEs or equivalent	1.5	1.9	3.3	-1.8	-1.5	-1.5	1.4	-1.4	-1.5	-1.5	-1.6	-1.4	-1.5	-1.5	-0.5	1.4	-0.8	-0.9	-1.8	-1.7
Forced vital capacity (FVC)	1.5	5.8	13.2	2.1	2.9	1.4	2.1	2.7	2.9	2.9	2.2	3.1	3.0	2.9	2.4	1.0	3.6	2.6	1.7	-0.1
Neuroticism score	1.5	3.1	5.8	2.4	2.1	1.9	-1.7	1.9	2.1	2.0	2.4	1.5	2.1	2.1	0.2	-2.0	1.7	0.6	1.4	1.3
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.5	12.3	-0.5	-1.3	-1.7	-2.1	-1.5	-1.4	-1.3	-0.7	-1.7	-1.4	-1.3	-3.5	-1.3	-1.6	-2.1	-1.3	0.1
Happiness	1.5	1.8	4.6	2.1	1.4	1.4	-1.6	0.9	1.4	1.5	1.6	1.1	1.3	1.4	-1.2	-1.9	1.7	-0.1	0.7	1.1
Commuting to job workplace: Car/motor vehicle	1.5	1.8	3.6	-1.3	-1.6	-1.8	0.8	-1.1	-1.4	-1.4	-1.6	-1.1	-1.6	-1.7	-0.7	1.8	-1.1	0.1	-0.6	-1.9
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	8.2	0.9	1.5	1.4	0.9	1.4	1.6	1.5	1.2	1.4	1.7	1.5	2.9	-0.1	1.3	1.2	0.9	0.3
Bipolar Disorder (2011)	1.4	1.3	10.5	0.6	-0.4	-0.7	-3.2	-0.4	-0.4	-0.6	0.0	-1.1	0.0	-0.4	-2.5	0.0	-1.2	-1.7	-0.3	0.5
Medication: Ramipril	1.4	1.8	4.9	-1.1	-1.5	-0.9	-1.8	-1.0	-1.5	-1.5	-1.1	-1.8	-1.6	-1.5	-1.5	-0.9	-2.2	-1.2	-0.5	0.2
Forced vital capacity (FVC), Best measure	1.4	5.2	13.3	2.0	2.7	1.2	2.2	2.6	2.8	2.8	2.1	2.9	2.9	2.7	2.0	1.1	3.6	2.3	1.3	-0.4
Had major operations	1.4	1.7	3.6	-0.9	-1.1	-1.1	-0.4	-1.9	-1.4	-1.2	-1.1	-1.6	-1.1	-1.1	-1.6	0.4	-0.7	-1.7	-1.9	-1.9
Breast cancer (self-reported)	1.4	1.7	3.5	1.1	1.5	1.6	0.2	1.5	1.2	1.1	1.3	1.6	1.6	1.5	1.5	-0.6	1.5	1.9	1.6	0.1
Average weekly champagne plus white wine intake	1.4	1.9	5.1	-0.8	-1.2	-1.7	-0.6	-1.4	-1.2	-1.5	-1.1	-1.4	-1.2	-1.2	-2.3	-0.0	-0.8	-1.8	-1.8	-2.2
Blood Red Count	1.3	12.9	28.1	-2.3	-3.9	-3.4	-5.3	-3.3	-4.0	-4.2	-2.7	-4.0	-4.1	-3.9	-4.6	-3.3	-5.3	-3.2	-1.3	-0.5
Medication for hormone replacement therapy	1.3	1.5	2.7	0.6	1.4	1.3	1.3	1.1	1.3	1.5	1.1	1.2	1.5	1.4	1.6	0.9	1.6	1.4	0.8	0.1
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	3.5	-1.0	-1.2	-1.1	-1.2	-1.3	-1.3	-1.3	-0.9	-1.6	-1.2	-1.2	-1.9	-0.8	-1.6	-1.8	-1.4	-0.8
Mean time to correctly identify matches	1.3	2.4	3.9	-1.6	-1.7	-0.9	0.1	-1.9	-1.9	-2.0	-1.6	-1.7	-1.7	-1.7	-1.3	0.2	-1.8	-1.9	-2.0	-1.5
Medication: Aspirin	1.3	1.7	8.1	0.1	-0.8	-1.1	-2.9	-0.8	-0.8	-0.8	-0.4	-1.3	-0.9	-0.8	-2.4	-1.9	-1.1	-2.0	-0.8	0.9
Miserableness	1.3	2.2	4.4	2.0	1.5	1.5	-2.1	1.6	1.4	1.2	1.9	1.4	1.4	1.5	-0.3	-2.1	1.1	0.8	1.6	1.5
Ever depressed for a whole week	1.3	1.7	10.6	1.3	0.4	0.2	-3.2	0.1	0.2	0.1	0.7	-0.2	0.2	0.4	-3.3	-1.7	0.4	-1.5	-0.3	1.1
Commuting to job workplace: Cycle	1.3	1.6	5.2	1.2	1.3	1.6	-0.4	1.3	1.3	1.4	1.3	1.8	1.2	1.3	1.3	-0.5	0.9	0.3	1.0	2.3
Reaction Time	1.2	2.4	3.6	-1.4	-1.7	-1.1	-0.3	-1.8	-1.8	-1.9	-1.5	-1.4	-1.7	-1.7	-1.7	-0.3	-1.8	-1.8	-1.8	-1.8
HDL Cholesterol	1.2	2.0	4.1	-1.9	-1.7	-0.6	1.7	-1.2	-1.5	-1.6	-1.9	-1.3	-1.5	-1.6	0.3	2.0	-1.4	-0.4	-1.0	-1.3
Relative age of first facial hair	1.2	2.4	8.6	-0.9	-1.6	-1.0	-1.4	-1.7	-1.8	-1.9	-1.3	-1.7	-1.7	-1.6	-2.9	-0.7	-1.9	-1.8	-1.2	-0.4
Asthma	1.2	2.3	4.7	-1.7	-1.6	-1.4	0.7	-1.9	-1.6	-1.6	-1.7	-2.2	-1.8	-1.6	-1.2	1.2	-1.6	-1.6	-1.8	-1.0
Length of working week for main job	1.2	1.3	3.0	-1.3	-1.3	-0.9	0.3	-1.3	-1.3	-1.4	-1.2	-1.7	-1.3	-1.3	-0.9	0.5	-1.0	-0.7	-1.2	-1.2
Heart disease (mother)	1.2	1.5	3.9	-0.8	-1.2	-1.4	-1.1	-1.4	-1.3	-1.4	-0.9	-1.2	-1.2	-1.2	-2.0	-0.8	-1.3	-1.6	-1.1	-0.3
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	2.5	-1.5	-1.2	-1.0	0.0	-1.3	-1.3	-1.0	-0.9	-1.5	-1.2	-1.2	-1.0	-0.7	-1.4	-1.3	-1.5	-1.6
Mouth/teeth dental problems: Mouth ulcers	1.2	1.8	11.5	0.7	-0.2	0.6	-3.4	-0.2	-0.2	-0.3	0.6	-0.7	-0.3	-0.2	-2.3	-3.3	-0.2	-1.7	-0.8	0.4
Pain type(s) experienced in last month: Hip pain	1.2	1.5	2.9	-1.3	-1.3	-1.7	-0.4	-1.3	-1.4	-1.3	-1.2	-1.4	-1.2	-1.3	-1.2	0.3	-1.6	-0.9	-1.1	-1.4
Medication: Lisinopril	1.2	1.5	5.3	-1.3	-1.4	-1.3	-0.6	-1.2	-1.5	-1.5	-1.2	-1.7	-1.1	-1.3	0.0	0.1	-2.3	-0.4	-0.3	-1.6
Respiratory disease	1.1	2.4	4.0	-1.3	-1.7	-0.9	-0.9	-1.9	-1.8	-1.9	-1.5	-1.9	-1.8	-1.7	-1.9	0.1	-1.6	-2.0	-1.7	-0.9
Chronotype (morning person)	1.1	2.6	5.0	1.7	1.6	1.6	1.2	1.8	1.8	1.6	1.2	2.2	1.6	1.7	1.2	0.8	2.0	2.2	1.9	1.4
Number of treatments/medications taken	1.1	2.0	4.4	-1.2	-1.6	-1.4	-1.4	-1.5	-1.8	-1.6	-1.3	-1.4	-1.7	-1.6	-2.1	-0.2	-1.8	-1.6	-1.1	0.1
Frequency of depressed mood in last 2 weeks	1.1	1.6	6.6	-0.5	-0.9	-1.5	-1.5	-1.3	-1.0	-1.1	-0.5	-1.3	-0.9	-0.9	-2.6	-1.0	-0.8	-2.1	-1.5	0.0
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.7	-1.0	-1.0	-1.4	0.8	-1.1	-1.0	-0.9	-1.1	-1.4	-1.0	-1.0	-1.1	1.3	-0.8	-0.6	-1.2	-1.6
Medication: Atenolol	1.1	1.4	6.8	-0.2	-1.2	-1.0	-1.5	-1.3	-1.1	-1.1	-0.9	-1.0	-1.3	-1.2	-2.6	-0.7	-1.1	-1.5	-0.8	-0.2
Qualifications: None of the above	1.1	2.3	6.5	-2.1	-1.6	-0.0	2.1	-1.6	-1.5	-1.5	-1.9	-1.7	-1.5	-1.6	0.7	2.6	-1.6	-0.7	-1.4	-0.9
Father’s age at death	1.1	1.5	3.1	1.8	1.5	0.0	-0.1	1.7	1.7	1.6	1.6	1.4	1.6	1.5	0.4	-1.1	1.5	0.3	0.4	0.0
Hair/balding pattern: Pattern 3	1.1	1.7	3.8	0.8	1.3	1.9	0.1	1.5	1.2	1.2	1.3	1.2	1.3	1.2	2.0	-0.8	0.7	1.7	1.8	1.4
Tense / ‘highly strung’	1.1	1.9	5.7	1.6	1.5	1.5	-1.9	1.3	1.6	1.6	2.0	0.5	1.6	1.5	0.3	-2.4	0.8	0.2	1.0	0.2
Blood clot in the leg (DVT)	1.1	1.5	10.0	-1.4	-0.8	-0.2	3.2	-0.8	-0.8	-1.0	-1.2	-0.5	-0.9	-0.8	0.1	2.2	-0.1	0.0	-1.4	-1.3
Migraine (self-reported)	1.1	1.3	3.3	1.0	1.1	0.9	-0.4	1.3	1.2	1.2	1.1	1.7	1.1	1.2	1.0	0.1	1.1	0.9	1.6	1.8
Alcohol drinker status: Previous	1.1	1.3	8.6	0.7	-0.3	-0.5	-2.9	-0.4	-0.4	-0.5	0.3	-0.2	-0.5	-0.3	-2.5	-1.9	-0.7	-1.4	-0.4	0.4
Alzheimer’s Disease (in father)	1.0	1.1	2.2	-1.3	-1.3	-0.1	0.2	-1.0	-1.5	-1.4	-1.3	-0.9	-1.4	-1.3	-0.8	0.2	-1.5	-0.8	-0.9	-0.1
Lupus	1.0	1.5	2.9	-1.7	-1.4	-0.8	0.3	-1.5	-1.6	-1.7	-1.5	-1.4	-1.3	-1.3	-0.2	1.3	-1.5	-0.8	-1.0	-0.8
Primary Biliary Cirrhosis	1.0	1.4	5.4	-1.2	-1.3	-0.8	-0.0	-1.3	-1.0	-1.0	-1.1	-2.3	-1.2	-1.3	-0.6	0.2	-1.6	-1.3	-1.4	-1.2
Neuroticism	1.0	2.3	4.5	2.0	1.8	1.5	-1.6	1.8	1.9	1.7	2.1	1.2	1.8	1.8	0.1	-1.9	1.5	0.3	1.1	1.1
Severe depression (siblings)	1.0	1.1	4.9	1.1	0.7	0.3	-1.6	0.8	0.6	0.6	0.9	0.8	0.5	0.7	-0.7	-1.8	0.0	0.9	1.8	2.2
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	2.8	1.3	0.9	0.9	-1.7	1.1	1.0	1.2	1.0	0.7	0.7	0.9	-0.1	-1.4	1.1	0.8	1.3	1.4
Commuting to job workplace: Public transport	1.0	1.2	6.5	1.1	0.9	0.0	-2.2	0.5	0.7	0.7	1.2	0.4	0.9	0.9	-0.5	-2.5	0.5	-1.0	-0.0	1.6
Number of operations (self-reported)	1.0	1.5	3.7	-1.3	-1.1	-0.2	-0.1	-1.6	-1.4	-1.3	-1.1	-1.6	-1.1	-1.1	-0.9	0.6	-1.3	-1.5	-1.5	-1.9
Average weekly beer plus cider intake	1.0	1.5	8.6	-1.4	-1.0	-0.7	2.3	-1.0	-1.0	-0.9	-1.4	-0.4	-1.0	-1.0	0.6	2.9	-1.0	0.5	-0.4	-0.4
Breast Cancer	0.9	2.1	4.0	-1.8	-1.4	-1.8	0.8	-2.0	-1.8	-1.8	-1.2	-1.3	-1.4	-1.4	-0.9	0.7	-1.6	-1.6	-2.0	-1.0
Coronary Artery Disease (CAD)	0.9	1.1	3.2	-0.8	-1.8	-0.7	-0.7	-1.6	-1.2	-1.1	-0.8	-1.2	0.0	-1.5	-1.4	0.0	-1.2	-0.8	-0.7	0.3
Hand grip strength (left)	0.9	2.3	5.8	0.5	1.3	0.4	2.3	1.5	1.5	1.4	0.8	2.4	1.2	1.3	1.8	1.6	1.6	2.0	1.5	1.6
Townsend deprivation index at recruitment	0.9	1.2	8.5	0.5	-0.4	-0.2	-2.9	-0.6	-0.5	-0.6	0.0	-0.6	-0.4	-0.4	-1.9	-2.1	-1.2	-1.2	0.1	0.8
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	4.9	-1.5	-0.7	0.4	2.2	-0.4	-0.6	-0.7	-1.0	-0.7	-0.6	-0.7	1.3	2.2	-0.4	0.2	-0.7	-0.6
Worrier / anxious feelings	0.9	1.8	2.7	1.6	1.5	1.0	-0.5	1.6	1.5	1.4	1.6	1.4	1.5	1.5	0.7	-0.8	1.3	1.3	1.6	1.7
Exposure to tobacco smoke at home	0.9	1.0	3.3	-0.9	-0.8	-0.7	-0.2	-1.2	-1.2	-1.2	-0.8	-0.8	-0.9	-0.8	-1.8	0.2	-1.4	-1.3	-1.2	-0.5
Birth weight	0.9	2.0	8.2	1.5	1.8	1.0	0.5	1.5	2.0	2.0	1.4	1.0	1.8	1.8	0.9	0.2	2.9	0.2	-0.3	-0.9
Number of full brothers	0.9	1.1	3.0	-1.1	-1.3	-1.1	-0.3	-1.1	-1.4	-1.2	-1.2	-1.2	-1.4	-1.4	-1.2	-0.2	-1.7	-0.2	-0.0	0.3
Mood swings	0.9	1.5	4.8	1.8	1.2	1.1	-2.2	1.2	1.2	1.1	1.5	0.8	1.2	1.2	-0.9	-1.7	1.0	0.7	1.3	0.7
Asthma (self-reported)	0.9	1.9	4.2	-1.4	-1.5	-1.1	0.3	-1.7	-1.5	-1.5	-1.4	-2.1	-1.6	-1.5	-1.2	0.8	-1.4	-1.6	-1.6	-0.9
Eye problems/disorders: Glaucoma	0.9	1.1	5.5	0.0	0.9	0.3	2.3	0.7	0.8	0.8	0.3	0.8	1.0	0.9	1.3	1.5	1.1	1.5	0.7	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	4.2	1.2	0.8	0.7	-2.1	0.6	0.6	0.7	1.2	0.4	0.7	0.8	-0.9	-1.8	0.4	-0.3	0.6	1.7
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	5.5	-0.1	-0.5	-0.8	-1.9	-0.8	-0.4	-0.5	-0.1	-1.4	-0.5	-0.5	-2.3	-1.2	-0.5	-2.1	-1.6	-0.9
Shortness of breath walking on level ground	0.8	1.0	3.8	-0.5	-0.8	-0.7	-0.1	-1.2	-0.8	-0.5	-0.6	-1.2	-0.8	-0.8	-1.4	0.1	-0.1	-1.9	-2.0	-1.2
Illnesses of siblings: Diabetes	0.8	1.0	2.1	-1.2	-1.2	-0.6	0.5	-1.4	-1.4	-1.5	-1.2	-1.0	-1.3	-1.2	-0.3	0.7	-0.9	-0.5	-0.7	0.2
Handedness (chirality/laterality): Left-handed	0.8	1.0	5.4	-1.2	-0.3	-0.5	2.3	-0.2	-0.2	-0.2	-0.7	-0.1	-0.2	-0.3	1.6	2.3	-0.2	1.0	-0.0	-0.5
Eye problems/disorders: Cataract	0.8	0.9	3.0	-1.3	-0.7	-1.3	1.7	-0.8	-0.7	-0.6	-1.0	-0.8	-0.7	-0.7	-0.2	1.7	-0.4	-0.2	-1.2	-1.3
Medication: Atorvastatin	0.8	0.9	2.2	-0.5	-0.9	-0.2	-1.0	-1.0	-1.0	-1.1	-0.8	-1.4	-1.0	-0.9	-1.4	-0.5	-1.1	-1.5	-1.0	-0.8
Schizophrenia vs Biploar Disorder	0.7	0.9	4.9	-0.0	-0.4	-1.6	-1.5	-0.7	-0.5	-0.6	-0.2	-0.8	-0.5	-0.4	-2.2	-0.6	-0.6	-1.3	-1.0	-0.2
Lung FEV1/FVC ratio	0.7	3.6	9.7	0.8	1.7	2.1	2.0	2.3	1.9	2.0	1.3	2.0	1.9	1.7	3.1	1.0	2.3	2.8	1.8	0.5
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	5.8	-0.7	0.3	-0.3	2.3	0.6	0.2	0.1	-0.3	0.5	0.3	0.3	1.3	2.4	0.6	1.6	0.5	0.3
Loud music exposure frequency	0.7	0.7	1.6	-1.0	-1.1	-0.7	-0.4	-0.9	-1.2	-1.2	-1.0	-0.9	-1.1	-1.1	-0.8	0.3	-1.0	-0.3	-0.4	-0.8
Number of children fathered	0.7	0.8	2.1	-0.7	-1.0	0.1	-1.1	-1.0	-1.1	-1.1	-0.9	-0.7	-1.2	-1.0	-1.2	-0.4	-1.4	-0.8	-0.4	0.4
Leg pain on walking	0.7	0.9	1.9	-0.9	-1.0	-0.5	0.4	-0.9	-1.0	-0.8	-1.1	-0.9	-1.1	-1.0	-1.4	1.3	-0.9	-0.8	-1.2	-0.8
Depression (Nagel 2018)	0.6	1.0	3.9	1.2	0.7	0.5	-2.0	0.1	0.4	0.4	1.1	0.2	0.7	0.7	-1.9	-1.7	0.5	-0.9	-0.1	0.7
Ulcerative Colitis	0.6	0.9	2.6	-0.9	-1.2	-0.7	-0.4	-1.1	-1.3	-1.3	-1.0	-1.0	-1.3	-1.2	-0.3	0.3	-1.6	-0.9	-0.6	0.3
Hand grip strength (right)	0.6	1.6	4.1	0.4	1.1	0.3	2.0	1.2	1.1	1.0	0.5	2.0	0.9	1.1	1.2	1.3	1.6	1.5	1.1	1.9
Sitting height	0.6	4.2	32.6	-0.9	0.9	0.1	5.7	0.7	0.9	1.0	-0.2	1.4	1.0	0.9	2.4	3.7	1.8	1.4	-1.0	-3.1
High blood pressure (mother)	0.6	0.9	3.7	-0.5	-1.0	-1.5	-0.8	-0.6	-0.9	-0.8	-0.8	-0.5	-1.1	-1.0	-0.2	-0.5	-1.5	0.1	0.6	1.9
Medication: Ventolin 100micrograms inhaler	0.6	0.8	1.4	-1.0	-1.2	-0.9	-0.5	-1.0	-1.0	-1.1	-1.0	-1.1	-1.1	-1.2	-0.1	0.5	-1.0	-0.5	-0.5	-0.8
Medication: Seretide 50 evohaler	0.6	0.7	4.5	-0.9	-0.4	-0.2	2.1	-0.6	-0.4	-0.3	-0.8	-0.2	-0.4	-0.4	0.6	2.1	-0.1	0.4	-0.4	-0.6
Friendships satisfaction	0.6	0.7	2.2	1.3	0.8	-0.4	-1.3	0.8	0.8	0.8	1.2	0.5	0.8	0.8	-0.5	-1.5	0.7	-0.0	0.4	0.1
Ever taken oral contraceptive pill	0.6	0.6	1.4	-0.5	-0.8	-0.8	-1.0	-0.8	-0.9	-0.9	-0.6	-0.7	-0.7	-0.8	-1.2	-0.3	-1.0	-0.9	-0.5	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	4.0	0.6	0.8	2.0	-0.2	0.8	0.6	0.8	0.8	0.9	0.7	0.8	1.1	-0.5	0.5	0.5	0.7	1.2
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	6.8	-0.9	-0.4	0.1	2.6	-0.4	-0.5	-0.6	-0.8	-0.2	-0.6	-0.4	0.2	1.7	0.3	0.3	-0.9	-0.9
HbA1C	0.5	0.5	2.3	0.9	0.7	0.7	0.1	0.4	0.5	0.6	0.7	0.7	0.8	0.7	0.2	0.4	0.9	1.5	1.2	-0.3
Rheumatoid Arthritis	0.5	0.7	4.6	-0.3	0.2	0.0	2.1	0.3	0.1	0.3	-0.1	0.7	0.1	0.1	1.4	1.3	0.3	1.3	0.3	-0.8
Systolic Blood Pressure	0.5	2.7	17.7	0.8	0.2	0.4	-2.8	1.2	0.3	0.3	0.3	0.5	0.1	0.2	0.7	-1.3	-1.6	1.8	3.5	4.2
Sensitivity / hurt feelings	0.5	0.8	2.3	1.2	1.1	1.0	-1.0	1.1	1.0	0.8	1.3	0.6	1.2	1.1	0.1	-1.5	0.5	-0.0	0.5	0.3
Hayfever, allergic rhinitis or eczema	0.5	1.2	2.2	0.8	1.3	0.8	1.3	1.2	1.2	1.3	0.8	1.3	1.3	1.3	1.1	0.6	1.5	1.0	0.6	0.9
Stomach or abdominal pain in last month	0.5	0.6	2.8	1.3	0.6	-0.6	-1.2	0.2	0.5	0.8	0.9	0.1	0.6	0.6	-1.7	-0.8	0.9	-0.8	-0.4	0.2
Prospective memory result	0.5	0.6	2.4	-0.7	-0.5	0.8	1.6	-0.5	-0.4	-0.4	-0.6	-0.3	-0.5	-0.5	0.5	1.1	-0.3	-0.8	-1.2	-1.2
Medication: Amlodipine	0.5	0.6	3.3	-1.3	-0.8	-0.7	0.7	-0.4	-0.7	-0.6	-0.8	-0.4	-0.8	-0.8	1.8	0.4	-1.2	-0.1	-0.1	0.0
Age at first live birth	0.5	0.9	2.4	1.1	1.1	0.8	0.3	1.2	1.2	1.0	1.0	1.5	1.0	1.1	1.0	-0.6	1.3	0.8	0.6	0.6
Knee pain experienced in last month	0.5	0.8	4.2	-1.2	-0.7	-0.6	1.7	-1.0	-0.9	-0.8	-1.1	-0.3	-0.8	-0.7	0.3	2.1	-0.3	0.5	-0.3	-0.0
Loneliness, isolation	0.5	0.6	3.3	-0.5	-0.7	-0.6	-0.9	-1.0	-0.8	-0.9	-0.3	-0.9	-0.7	-0.6	-1.8	-0.2	-0.7	-1.1	-0.7	-0.1
Ever had bowel cancer screening	0.5	0.6	5.0	0.5	0.0	0.2	-2.2	-0.3	-0.2	-0.3	0.3	-0.6	-0.1	-0.0	-1.2	-1.5	0.2	-1.2	-0.5	0.1
Medication: Gliclazide	0.5	0.5	2.3	0.2	-0.5	-1.5	-1.1	-0.6	-0.4	-0.4	-0.2	-0.9	-0.5	-0.6	-1.5	-0.5	-0.8	-0.6	-0.3	-0.5
Wears glasses or contact lenses	0.5	0.6	2.4	-0.0	-0.4	-0.1	-1.4	-0.7	-0.5	-0.5	-0.1	-0.7	-0.4	-0.4	-1.5	-0.8	0.0	-1.4	-1.1	-0.3
Ever had prostate specific antigen (PSA) test	0.5	0.6	3.1	-0.6	-0.4	-0.5	-0.5	-0.6	-0.4	-0.4	-0.3	-1.1	-0.4	-0.4	-0.4	-0.6	-0.2	-1.8	-1.7	-1.1
Myopia	0.5	0.7	4.1	1.0	0.4	-0.0	-2.0	0.5	0.5	0.5	0.6	-0.3	0.3	0.4	-1.1	-1.5	0.6	-0.9	-0.4	-0.3
Basal cell carcinoma (self-reported)	0.5	0.5	1.7	-0.3	-0.4	-0.7	-0.9	-0.7	-0.5	-0.6	-0.6	-1.0	-0.5	-0.4	-1.3	0.5	-0.2	-1.0	-1.0	-1.1
Heart disease (siblings)	0.5	0.6	4.2	0.5	0.1	-0.1	-1.8	0.5	0.1	-0.0	0.3	-0.0	-0.1	0.1	-0.0	-1.4	-0.0	0.1	0.9	2.0
Type 2 Diabetes (T2D) (2012)	0.4	0.4	1.6	-0.8	-0.6	-0.5	-0.4	-0.6	-0.7	-0.9	-0.9	-0.7	-0.9	-0.7	0.1	0.5	-1.3	-0.5	-0.3	-0.4
Systolic blood pressure, automated reading	0.4	1.2	9.3	0.4	0.2	0.7	-1.2	1.1	0.4	0.4	0.0	0.1	0.2	0.2	0.7	0.0	-0.9	1.5	2.3	3.1
Diabetes (father)	0.4	0.5	1.3	0.7	0.7	0.4	0.6	0.9	0.9	0.9	0.4	0.7	0.8	0.7	1.1	0.4	0.7	1.2	0.9	0.4
Relative age voice broke	0.4	0.5	1.7	-0.6	-0.8	-0.3	-0.5	-0.9	-0.9	-1.1	-0.6	-0.7	-0.7	-0.8	-0.5	-0.8	-1.3	-0.8	-0.4	-0.1
Age when periods started (menarche)	0.4	1.0	4.0	-0.2	-0.9	0.1	-2.0	-0.8	-0.9	-1.0	-0.5	-0.9	-0.8	-0.9	-1.8	-1.3	-1.6	-0.9	-0.1	-0.2
Time employed in main current job	0.4	0.4	2.9	0.1	0.2	0.7	0.8	0.4	0.5	0.6	0.2	0.5	0.1	0.3	1.5	0.3	0.1	0.2	0.5	1.7
Alcohol intake versus 10 years previously	0.4	0.6	2.3	-0.6	-0.8	-1.5	-0.6	-0.8	-0.8	-0.7	-0.5	-0.4	-0.9	-0.8	-0.9	-0.3	-1.5	-0.9	-0.5	0.5
Birth weight of first child	0.4	0.8	5.0	-0.4	0.0	-0.8	2.0	-0.3	-0.0	-0.0	-0.4	-0.3	0.1	0.0	-0.4	1.7	0.8	0.1	-1.0	-2.2
Ever highly irritable/argumentative for 2 days	0.4	0.5	3.0	0.5	-0.1	-0.4	-1.7	-0.0	-0.1	-0.0	0.4	-0.7	-0.1	-0.1	-1.1	-1.1	-0.6	-0.9	0.0	1.3
Headache pain in last month	0.4	0.7	3.6	1.0	0.4	-0.7	-1.7	-0.2	0.2	0.3	0.9	0.4	0.3	0.4	-1.9	-1.2	0.5	-0.4	0.3	1.0
Medication: Omeprazole	0.4	0.4	2.2	0.4	0.5	1.5	-0.1	0.6	0.4	0.7	0.6	0.7	0.4	0.5	1.2	-0.4	0.3	0.3	0.5	1.0
Average weekly red wine intake	0.4	0.6	3.5	-0.7	-0.4	-0.2	0.3	-0.8	-0.5	-0.5	-0.7	-0.5	-0.4	-0.4	-1.0	0.7	0.1	-0.8	-1.5	-1.9
Guilty feelings	0.4	0.6	1.8	0.8	0.9	1.3	0.7	0.9	1.0	1.0	0.6	0.6	1.0	0.9	0.3	0.6	1.1	0.3	0.1	-0.2
Alcohol drinker status: Never	0.4	0.5	2.0	-0.4	-0.3	-0.3	0.8	-0.7	-0.2	-0.2	-0.4	-0.6	-0.2	-0.3	-0.6	1.1	0.6	-0.7	-1.3	-1.4
Alzheimer’s Disease (in mother)	0.3	0.4	1.0	-0.8	-0.7	-0.5	-0.2	-0.7	-0.9	-1.0	-0.8	-0.6	-0.7	-0.7	-0.3	0.4	-0.8	-0.3	-0.2	-0.4
Diabetes (mother)	0.3	0.3	1.0	-0.6	-0.6	-0.7	-0.2	-0.7	-0.7	-0.6	-0.6	-0.7	-0.6	-0.6	-1.0	0.4	-0.7	-0.4	-0.2	-0.0
Alcohol usually taken with meals	0.3	0.5	2.4	0.9	0.4	0.2	-1.6	0.2	0.4	0.4	0.7	0.0	0.4	0.4	-0.8	-1.4	0.7	-0.8	-0.2	-0.3
Had other major operations	0.3	0.4	2.5	0.2	-0.1	0.4	-1.6	0.1	-0.1	-0.1	0.2	-0.4	-0.2	-0.1	-0.8	-1.3	-0.6	-0.6	0.1	0.6
Medication: Lansoprazole	0.3	0.3	1.8	-0.4	-0.0	0.8	0.1	-0.4	-0.1	-0.0	0.0	-0.3	0.0	-0.1	-0.9	-0.2	0.4	-1.1	-1.4	-0.8
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.9	-0.7	-0.5	0.8	-0.2	-0.8	-0.8	-0.9	-0.5	-0.8	-0.7	-0.5	-0.3	0.2	-0.9	-0.4	-0.3	0.9
Exposure to tobacco smoke outside home	0.3	0.3	1.7	-0.3	-0.3	-0.8	-0.8	-0.6	-0.7	-0.6	-0.2	-0.5	-0.4	-0.3	-1.3	-0.8	-0.5	-0.5	-0.2	-0.3
Worry too long after embarrassment	0.3	0.6	4.6	-0.6	-0.0	0.0	2.1	-0.1	-0.0	0.1	-0.3	0.6	0.1	-0.0	1.7	1.3	-0.1	0.5	-0.1	-0.5
Eye problems/disorders: None of the above	0.3	0.4	2.0	0.6	0.1	0.4	-1.4	0.4	0.1	-0.1	0.2	0.5	0.0	0.0	0.4	-0.9	-0.2	0.2	1.0	1.2
Mouth/teeth dental problems: Loose teeth	0.3	0.4	2.4	-0.5	-0.0	-1.1	1.1	-0.3	-0.4	-0.4	-0.3	-0.0	-0.1	-0.1	-0.3	1.6	-0.2	0.9	0.2	-1.0
Neck or shoulder pain in last month	0.3	0.4	2.0	0.8	0.5	-0.1	-1.4	0.4	0.3	0.5	0.6	-0.1	0.4	0.5	-0.8	-0.7	0.3	-0.1	0.4	1.1
Medication: Ibuprofen	0.3	0.3	1.1	-0.1	-0.4	-0.4	-1.0	-0.3	-0.3	-0.3	-0.1	-0.5	-0.3	-0.3	-1.0	-0.9	-0.7	-0.8	-0.3	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	2.1	-0.3	0.0	-0.1	0.8	0.0	-0.1	0.1	-0.3	0.8	0.1	0.1	1.0	1.3	0.0	0.7	0.7	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.6	0.2	0.4	0.8	-0.3	0.7	0.4	0.4	0.5	0.4	0.4	0.4	0.9	-0.8	0.0	0.4	0.6	1.2
Back pain experienced in last month	0.3	0.5	3.8	-0.2	-0.4	-0.7	-0.4	-0.5	-0.5	-0.5	-0.5	-0.7	-0.4	-0.4	-1.9	0.6	-0.1	-0.3	-0.6	-1.2
Age started oral contraceptive pill	0.3	0.4	1.1	0.2	0.6	0.5	0.7	0.9	0.6	0.4	0.5	0.6	0.6	0.6	0.7	0.4	0.7	1.0	0.7	0.4
Allergy or Eczema	0.2	0.5	4.3	-0.3	0.5	0.4	2.1	0.5	0.3	0.3	-0.0	0.4	0.4	0.5	1.1	1.3	0.8	0.3	-0.3	-0.1
Tanning	0.2	2.0	7.1	0.7	1.1	1.1	1.5	1.4	1.2	1.1	0.8	1.9	1.2	1.1	2.2	0.8	0.9	2.7	2.1	1.0
Medication: Co-codamol	0.2	0.2	0.6	0.2	0.6	0.8	-0.1	0.5	0.4	0.5	0.5	0.3	0.6	0.6	0.5	-0.2	0.4	0.4	0.3	-0.1
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.8	-0.7	-0.2	-0.3	0.9	-0.4	-0.2	-0.2	-0.3	-0.3	-0.3	-0.2	0.8	0.6	0.1	-0.2	-0.6	0.3
Falls in the last year	0.2	0.3	1.7	0.3	-0.1	0.1	-0.9	-0.2	-0.0	0.2	0.1	-0.2	-0.1	-0.1	-1.3	-0.4	-0.1	-0.9	-0.7	-0.9
Number of live births	0.2	0.2	1.0	-0.3	-0.2	1.0	0.2	-0.0	-0.2	-0.3	-0.4	-0.4	-0.1	-0.2	0.7	0.5	-1.0	0.7	0.7	-0.1
Comparative body size at age 10	0.2	0.5	4.7	-0.1	0.1	-0.6	1.1	0.2	0.2	0.3	-0.4	0.6	-0.0	0.1	0.5	2.2	1.0	0.1	-0.1	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.4	0.2	0.5	0.6	0.5	0.4	0.5	0.6	0.2	0.6	0.5	0.5	0.4	0.1	0.6	-0.1	-0.3	0.4
Alcohol intake frequency.	0.2	0.5	1.1	1.0	0.8	-0.1	-0.5	0.7	0.8	0.8	1.0	0.9	0.8	0.8	-0.2	-0.5	1.0	0.6	0.7	0.3
Age at last live birth	0.2	0.3	1.5	0.7	0.3	0.7	-1.0	0.7	0.4	0.2	0.4	0.5	0.2	0.3	0.2	-1.2	-0.1	0.3	0.6	0.3
Family relationship satisfaction	0.2	0.2	1.6	0.7	0.1	-0.0	-0.6	0.1	0.4	0.5	0.2	-0.2	-0.0	0.1	-1.3	-0.3	0.3	-0.5	-0.4	-0.0
Osteoarthritis (self-reported)	0.2	0.2	1.1	-0.6	-0.3	0.6	0.2	-0.6	-0.7	-0.7	-0.3	-0.4	-0.2	-0.3	-0.3	-0.1	-0.5	-0.2	-0.5	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	3.3	-0.0	0.4	0.1	0.8	0.6	0.3	0.3	0.1	0.8	0.4	0.4	1.8	0.4	0.5	1.1	0.7	0.6
Hearing aid user	0.2	0.2	0.6	0.1	0.5	0.3	0.7	0.4	0.4	0.4	0.2	0.4	0.5	0.5	-0.2	0.3	0.7	0.6	0.1	-0.6
Pain experienced in last month	0.2	0.3	3.7	-0.4	0.1	0.2	1.0	0.3	0.2	0.0	-0.2	0.2	0.1	0.1	1.9	0.3	-0.1	0.6	0.3	-0.3
Ovarian Cancer	0.1	0.1	1.2	-0.0	0.1	-0.3	-0.1	-0.1	0.1	0.3	0.3	-0.1	0.0	0.1	0.5	-0.9	0.0	-0.2	0.2	1.1
LDL Cholesterol	0.1	0.2	0.6	0.6	0.5	0.2	-0.3	0.4	0.4	0.4	0.6	0.5	0.4	0.5	0.1	-0.3	0.8	0.5	0.3	0.3
Triglycerides	0.1	0.2	0.9	0.5	0.6	0.5	-0.4	0.4	0.4	0.6	0.4	0.3	0.5	0.5	0.2	-0.5	1.0	0.4	0.3	-0.2
Waist Hip Ratio (WHR)	0.1	0.2	1.1	0.4	0.4	1.1	0.4	0.3	0.4	0.3	0.1	0.6	0.3	0.4	-0.2	0.3	0.3	0.5	0.7	1.0
Hypothyroidism (self reported)	0.1	0.3	2.0	0.3	0.3	-0.4	0.9	0.4	0.4	0.4	-0.1	0.3	0.3	0.3	-0.1	1.4	0.4	0.5	0.1	-0.7
Lung FVC	0.1	0.4	1.1	-0.8	-0.7	-1.0	-0.2	-0.7	-0.9	-0.7	-0.9	-0.5	-0.6	-0.7	-0.5	0.6	-0.1	0.0	-0.3	-0.8
Average weekly fortified wine intake	0.1	0.1	0.8	0.4	0.3	0.6	-0.1	0.5	0.4	0.2	0.5	0.4	0.3	0.3	0.2	-0.9	0.3	0.0	-0.0	-0.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.6	-0.2	0.0	0.4	0.8	0.1	-0.0	0.2	-0.3	0.0	0.0	-0.0	0.4	0.7	0.0	0.7	0.3	-0.2
Medication: Levothyroxine sodium	0.1	0.1	0.3	0.2	-0.1	-0.6	-0.5	0.4	0.2	0.3	-0.2	-0.4	-0.1	-0.1	-0.1	0.5	-0.1	-0.3	-0.1	0.3
Allergy	0.1	0.2	1.8	0.6	0.1	-0.1	-1.3	0.3	0.2	0.1	0.3	0.2	0.2	0.1	-0.1	-0.7	0.0	0.5	0.9	0.2
Peak expiratory flow (PEF)	0.1	0.2	1.1	-0.5	-0.0	-0.7	1.1	0.2	0.0	0.0	-0.1	0.4	0.1	0.0	1.1	0.7	0.2	0.2	-0.2	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.7	0.3	0.4	-0.3	0.3	0.5	0.4	0.5	0.1	0.1	0.4	0.4	-0.3	0.9	0.4	-0.1	-0.2	-0.2
Illnesses of father: Heart disease	0.1	0.2	0.5	0.4	0.4	-0.1	0.1	0.4	0.6	0.4	0.4	0.7	0.4	0.4	0.6	0.0	0.7	0.3	0.1	0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.6	-0.2	-0.3	0.3	-0.6	-0.3	-0.4	-0.2	-0.2	-0.2	-0.2	-0.3	-0.3	-0.1	-0.8	-0.7	-0.1	0.7

Hub : Genes

MARK3

Models

Trait associations