Best TWAS P=4.23e-17 · Best GWAS P=3.28e-17 conditioned to 0.0528
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | CCNE1 | 0.31 | 0.19 | lasso | 9 | 0.21 | 6.3e-12 | 8.4 | 7.5 | 7.0e-14 | 0.94 | 0 | 1.00 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | CCNE1 | 0.27 | 0.22 | lasso | 8 | 0.24 | 2.5e-19 | 8.4 | 7.5 | 4.6e-14 | 0.93 | 0 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | CCNE1 | 0.03 | 0.02 | blup | 39 | 0.02 | 4.5e-03 | 8.4 | 7.8 | 9.5e-15 | 0.90 | 0 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CCNE1 | 0.03 | 0.03 | enet | 5 | 0.03 | 3.2e-04 | 8.4 | -8.4 | 4.2e-17 | -0.91 | 0 | 0.99 | TRUE |