Best TWAS P=9.15e-09 · Best GWAS P=3.03e-09 conditioned to 0.00441
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | HAUS8 | 0.16 | 0.02 | lasso | 7 | 0.02 | 4.7e-03 | -4.8 | 5.4 | 7.8e-08 | 0.67 | 0.11 | 0.84 | FALSE |
| 2 | GTEx | Brain Frontal Cortex BA9 | GTPBP3 | 0.44 | 0.05 | lasso | 9 | 0.09 | 2.3e-03 | 3.9 | 5.8 | 9.1e-09 | -0.04 | 0.05 | 0.09 | TRUE |
| 3 | GTEx | Esophagus Muscularis | MYO9B | 0.13 | 0.02 | lasso | 5 | 0.05 | 9.5e-04 | -2.6 | 5.2 | 1.5e-07 | 0.61 | 0.26 | 0.60 | FALSE |
| 4 | GTEx | Muscle Skeletal | HAUS8 | 0.15 | 0.10 | lasso | 4 | 0.08 | 1.6e-08 | -4.9 | 5.3 | 9.6e-08 | 0.66 | 0.26 | 0.73 | FALSE |
| 5 | GTEx | Thyroid | ANKLE1 | 0.10 | 0.03 | lasso | 5 | 0.02 | 5.9e-03 | -4.6 | -5.4 | 6.4e-08 | -0.20 | 0.12 | 0.38 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HAUS8 | 0.05 | 0.06 | enet | 12 | 0.06 | 2.9e-12 | -4.9 | 5.2 | 2.5e-07 | 0.68 | 0.29 | 0.70 | FALSE |
| 7 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | HAUS8 | 0.21 | 0.11 | enet | 9 | 0.10 | 6.2e-05 | 5.7 | 5.1 | 3.1e-07 | 0.89 | 0.00 | 0.99 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GTPBP3 | 0.24 | 0.09 | lasso | 3 | 0.12 | 9.4e-13 | 3.9 | 5.5 | 5.1e-08 | 0.05 | 0.01 | 0.72 | FALSE |
| 9 | The Cancer Genome Atlas | Prostate Adenocarcinoma | HAUS8 | 0.13 | 0.10 | blup | 55 | 0.11 | 7.8e-12 | -4.8 | 5.2 | 1.9e-07 | 0.73 | 0.26 | 0.74 | FALSE |
| 10 | The Cancer Genome Atlas | Stomach Adenocarcinoma | HAUS8 | 0.06 | 0.04 | blup | 55 | 0.04 | 1.0e-03 | -4.9 | 5.6 | 2.5e-08 | 0.60 | 0.03 | 0.52 | TRUE |
| 11 | The Cancer Genome Atlas | Stomach Adenocarcinoma | OCEL1 | 0.18 | 0.08 | blup | 53 | 0.11 | 1.4e-08 | -4.6 | -5.6 | 2.3e-08 | -0.10 | 0.00 | 0.97 | TRUE |