TWAS
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Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Trunk fat-free mass
:
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chr20:49,975,801-52,810,143
Best TWAS P=3.65e-13 · Best GWAS P=8.93e-21 conditioned to 7.57e-07
50M
50.5M
51M
51.5M
52M
52.5M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Artery Tibial
ZFP64
0.10
0.03
lasso
4
0.06
3.4e-05
2.5
7.3
3.7e-13
-0.71
0.24
0.44
TRUE
3
GTEx
Cells Transformed fibroblasts
ZFP64
0.09
0.09
enet
5
0.09
1.9e-07
-2.6
6.3
2.4e-10
-0.44
0.55
0.39
TRUE
1
GTEx
Adipose Visceral Omentum
ZFP64
0.17
0.00
lasso
4
0.00
2.5e-01
6.3
5.3
1.0e-07
-0.12
0.06
0.25
FALSE
4
YFS
Blood
TSHZ2
0.10
0.03
bslmm
798
0.07
2.8e-22
-6.2
5.2
2.4e-07
-0.59
0.01
0.99
FALSE