[Hub]/) : Traits : Trunk fat-free mass : ← →

chr20:46,838,455-49,625,623

Best TWAS P=3.22e-14 · Best GWAS P=1.08e-13 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	NTR	Blood	SNORD12B	0.03	0.05	lasso	8	0.05	1.9e-14	7.4	-7.6	3.2e-14	-0.96	0.01	0.99	TRUE
2	CommonMind	Brain Pre-frontal Cortex	LOC284751	0.14	0.04	bslmm	442	0.08	9.1e-10	-3.0	-5.1	2.9e-07	-0.01	0.08	0.87	TRUE
11	METSIM	Adipose	ARFGEF2	0.04	0.03	lasso	12	0.02	9.8e-05	7.4	-7.5	4.6e-14	-0.98	0.02	0.98	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	ARFGEF2	0.05	0.04	lasso	5	0.05	3.2e-06	7.0	-7.5	8.4e-14	-0.94	0.00	1.00	FALSE
19	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C20orf199	0.05	0.06	lasso	4	0.06	1.0e-04	7.4	7.4	1.4e-13	0.92	0.00	0.96	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ARFGEF2	0.09	0.05	lasso	8	0.10	9.2e-13	7.0	-7.2	6.2e-13	-0.82	0.04	0.96	FALSE
10	GTEx	Testis	ARFGEF2	0.20	0.20	lasso	7	0.24	5.4e-11	6.0	-6.9	3.9e-12	-0.91	0.09	0.91	FALSE
3	GTEx	Cells Transformed fibroblasts	STAU1	0.08	0.03	lasso	6	0.02	2.3e-02	6.0	6.7	2.6e-11	0.85	0.07	0.80	FALSE
9	GTEx	Skin Sun Exposed Lower leg	CSE1L	0.08	0.03	lasso	2	0.03	9.5e-04	6.9	-6.6	4.3e-11	-0.81	0.35	0.38	FALSE
12	NTR	Blood	NCRNA00275	0.07	0.06	lasso	4	0.08	9.7e-25	-4.7	-6.6	4.5e-11	-0.53	1.00	0.00	FALSE
5	GTEx	Colon Sigmoid	CSE1L	0.18	0.12	lasso	11	0.09	4.4e-04	6.3	-6.4	1.2e-10	-0.80	0.09	0.87	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	DDX27	0.08	0.05	lasso	3	0.05	1.9e-05	7.4	6.4	1.2e-10	0.85	0.01	0.98	FALSE
6	GTEx	Esophagus Mucosa	CSE1L	0.09	0.06	lasso	4	0.06	6.9e-05	6.8	-6.3	2.6e-10	-0.80	0.13	0.83	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CSE1L	0.05	0.07	blup	50	0.07	3.2e-08	6.3	-6.3	2.7e-10	-0.80	0.05	0.95	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CSE1L	0.03	0.05	lasso	1	0.03	9.3e-05	6.0	-6.0	1.6e-09	-0.75	0.08	0.90	FALSE
8	GTEx	Lung	CSE1L	0.10	0.09	lasso	5	0.08	6.6e-07	6.1	-6.0	2.7e-09	-0.73	0.66	0.32	FALSE
20	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CSE1L	0.13	0.03	blup	50	0.07	1.4e-03	6.0	-5.9	4.6e-09	-0.60	0.02	0.45	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	CSE1L	0.04	0.02	enet	16	0.02	2.8e-03	5.4	-5.6	2.4e-08	-0.72	0.08	0.91	FALSE
4	GTEx	Colon Sigmoid	ARFGEF2	0.15	0.12	lasso	1	0.07	2.3e-03	5.4	-5.4	6.7e-08	-0.60	0.07	0.52	FALSE
7	GTEx	Esophagus Mucosa	ZFAS1	0.15	0.01	enet	16	0.01	8.9e-02	7.4	5.3	8.8e-08	0.69	0.01	0.95	FALSE
18	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C20orf199	0.04	0.00	enet	8	0.02	6.4e-03	2.8	5.3	1.3e-07	0.62	0.01	0.50	FALSE