Best TWAS P=1.94e-08 · Best GWAS P=1.04e-05 conditioned to 1.05e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CBR1 | 0.25 | 0.12 | enet | 29 | 0.20 | 9.5e-24 | -4.3 | -5.4 | 5.5e-08 | 0 | 0.01 | 0.92 | FALSE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | CBR1 | 0.45 | 0.09 | lasso | 5 | 0.22 | 5.1e-13 | 2.8 | -5.6 | 1.9e-08 | 0 | 0.01 | 0.85 | TRUE |