TWAS
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Traits
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Traits
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Trunk fat-free mass
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chr21:36,744,868-38,140,262
Best TWAS P=1.94e-08 · Best GWAS P=1.04e-05 conditioned to 1.05e-05
36.8M
37M
37.2M
37.4M
37.6M
37.8M
38M
38.2M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Colon Adenocarcinoma
CBR1
0.45
0.09
lasso
5
0.22
5.1e-13
2.8
-5.6
1.9e-08
0
0.01
0.85
TRUE
1
CommonMind
Brain Pre-frontal Cortex
CBR1
0.25
0.12
enet
29
0.20
9.5e-24
-4.3
-5.4
5.5e-08
0
0.01
0.92
FALSE