TWAS hub - CBR1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2530	0.0570	8.2e-13	0.118	0.109	0.199	0.174	0.181	3.2e-14	3.5e-13	9.5e-24	1.2e-20	1.6e-21
2	GTEx	Adipose Subcutaneous	0.2770	0.0950	2.0e-03	0.035	NA	0.107	NA	0.079	6.5e-04	NA	4.9e-09	NA	5.2e-07
3	GTEx	Brain Nucleus accumbens basal ganglia	0.2350	0.0850	4.7e-03	0.070	NA	0.017	NA	0.036	6.1e-03	NA	1.1e-01	NA	3.9e-02
4	GTEx	Cells Transformed fibroblasts	0.4790	0.0650	1.4e-07	0.179	NA	0.274	NA	0.257	2.0e-13	NA	1.2e-20	NA	2.6e-19
5	GTEx	Colon Transverse	0.3630	0.0670	5.7e-10	0.337	NA	0.266	NA	0.327	9.2e-17	NA	5.0e-13	NA	3.3e-16
6	GTEx	Nerve Tibial	0.3308	0.0688	1.2e-06	0.124	NA	0.175	NA	0.172	4.3e-09	NA	2.0e-12	NA	3.0e-12
7	GTEx	Pancreas	0.2960	0.0930	1.3e-04	0.169	NA	0.097	NA	0.226	1.3e-07	NA	7.0e-05	NA	6.2e-10
8	GTEx	Thyroid	0.1600	0.0470	1.6e-05	0.079	NA	0.107	NA	0.122	1.3e-06	NA	1.4e-08	NA	1.3e-09
9	NTR	Blood	0.0757	0.0241	1.5e-07	0.031	0.031	0.058	0.054	0.052	1.9e-10	3.3e-10	5.0e-18	7.4e-17	2.4e-16
10	YFS	Blood	0.0254	0.0116	5.3e-03	-0.001	0.007	0.003	0.008	-0.001	8.7e-01	1.4e-03	3.2e-02	7.9e-04	7.2e-01
11	TCGA	Breast Invasive Carcinoma	0.0771	0.0424	7.7e-03	0.017	0.002	0.009	NA	0.009	1.3e-04	1.1e-01	4.3e-03	NA	4.9e-03
12	TCGA	Colon Adenocarcinoma	0.4470	0.0880	1.6e-10	0.087	0.178	0.155	NA	0.222	9.6e-06	1.6e-10	2.9e-09	NA	5.1e-13
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.1766	0.0682	1.5e-07	0.023	0.037	0.039	NA	0.038	1.2e-03	4.3e-05	3.0e-05	NA	3.3e-05
14	TCGA	Ovarian Serous Cystadenocarcinoma	0.3410	0.1010	1.7e-04	0.050	0.028	-0.002	NA	0.030	2.5e-04	5.5e-03	5.2e-01	NA	4.0e-03
15	TCGA	Pancreatic Adenocarcinoma	0.2080	0.1120	1.4e-03	0.056	0.070	0.041	NA	0.045	2.2e-03	7.0e-04	7.7e-03	NA	5.6e-03
16	TCGA	Prostate Adenocarcinoma	0.2406	0.0771	4.3e-06	0.069	0.069	0.069	NA	0.097	9.8e-08	1.0e-07	9.3e-08	NA	2.5e-10
17	TCGA	Stomach Adenocarcinoma	0.2500	0.0830	7.9e-05	0.043	0.018	0.041	NA	0.072	4.3e-04	1.7e-02	6.0e-04	NA	6.8e-06
18	TCGA	Thyroid Carcinoma	0.4590	0.0760	7.1e-15	0.133	0.179	0.200	NA	0.183	6.3e-13	3.4e-17	3.6e-19	NA	1.7e-17

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Qualifications: CSEs or equivalent	5.6	7.4	14.4	3.2	2.6	2.5	1.4	3.0	3.4	3.4	2.4	1.4	-1.1	1.5	3.4	3.8	2.6	0.8	3.6	2.8	3.2
Lung cancer (father)	4.8	5.6	9.8	-2.8	-2.5	-1.9	-2.1	-1.8	-1.2	-2.5	-2.1	-2.5	-1.2	-3.0	-2.6	-2.3	-2.4	-1.4	-3.1	-2.8	-3.0
Comparative body size at age 10	3.8	10.4	20.4	-2.4	-4.5	-2.9	-3.1	-3.3	-0.9	-4.0	-3.8	-3.6	0.1	-3.4	-3.4	-2.6	-2.3	-3.1	-3.9	-3.4	-4.1
Chronic bronchitis/emphysema (mother)	3.4	4.0	10.8	-2.7	-1.8	-1.3	-1.9	-1.9	-1.8	-2.4	-1.4	-1.8	-1.2	-3.3	-2.1	-1.2	-1.6	0.5	-2.5	-1.9	-2.7
Smoking Status	3.0	7.1	15.4	2.9	3.1	2.4	1.9	2.5	2.1	3.5	2.8	1.8	-0.6	2.5	3.0	3.6	1.6	2.2	3.2	2.2	3.9
Emphysema/chronic bronchitis	3.0	3.4	9.9	-1.5	-2.3	-1.0	-3.1	-1.0	-1.7	-1.7	-0.9	-2.0	0.7	-1.5	-2.0	-1.3	-2.2	-0.9	-2.3	-2.3	-2.4
HDL Cholesterol	2.9	4.8	10.5	-1.8	-2.1	-2.2	-1.7	-2.3	-0.9	-2.8	-2.3	-2.0	-0.8	-2.0	-2.3	-1.9	-2.5	-0.8	-3.2	-2.9	-2.9
Health satisfaction	2.8	3.6	10.6	1.4	2.0	1.2	1.5	1.9	-1.3	2.2	3.3	2.5	-0.8	1.3	1.8	0.3	1.1	3.2	2.2	2.1	1.4
Medication: Atenolol	2.7	3.4	7.7	-1.4	-2.6	-0.8	-2.2	-1.8	-2.8	-2.2	-0.7	-1.3	1.1	0.3	-1.9	-2.6	-2.1	-1.3	-2.2	-2.0	-1.9
Current tobacco smoking	2.6	4.2	9.3	2.4	1.8	2.6	1.2	2.5	1.9	3.0	2.1	0.8	0.1	1.8	2.5	3.0	0.8	0.7	2.2	0.9	3.0
Breastfed as a baby	2.6	3.2	12.6	-0.3	-1.8	0.5	-1.8	1.0	2.2	0.6	-0.7	-3.6	-2.8	-2.4	-0.1	1.4	-1.9	-1.9	-1.1	-2.4	-1.1
Supplements: Vitamin C	2.6	3.0	8.1	-1.3	-1.9	-0.2	-2.1	-0.6	-0.1	-1.1	-1.5	-2.8	-2.0	-2.3	-1.5	0.1	-2.2	-1.2	-2.3	-2.6	-1.7
Prostate Cancer	2.5	3.5	8.7	-2.9	-1.4	-2.3	-1.0	-1.9	-1.7	-2.3	-2.2	-0.9	0.4	-1.8	-2.1	-2.2	-1.4	-0.6	-2.4	-1.7	-2.4
Trunk fat-free mass	2.4	13.9	31.6	-5.4	-2.4	-4.3	-2.3	-4.1	-3.8	-5.0	-3.8	-2.4	0.5	-3.6	-5.6	-2.6	-2.5	-0.3	-4.7	-2.6	-5.1
Trunk predicted mass	2.4	13.6	30.8	-5.4	-2.3	-4.3	-2.3	-4.1	-3.7	-5.0	-3.8	-2.4	0.4	-3.6	-5.5	-2.6	-2.5	-0.3	-4.7	-2.5	-5.0
Forced expiratory volume in 1-second (FEV1), predicted	2.4	4.9	13.1	-3.4	-1.4	-2.3	-1.7	-1.2	-2.0	-1.8	-1.5	-2.4	-1.4	-3.6	-3.0	0.1	-2.4	0.5	-2.8	-2.3	-2.8
Whole body fat-free mass	2.4	13.6	31.7	-5.3	-2.3	-4.3	-2.3	-4.1	-3.8	-5.0	-3.8	-2.4	0.6	-3.5	-5.6	-2.5	-2.6	-0.2	-4.7	-2.5	-5.0
Leg fat-free mass (left)	2.3	12.0	29.4	-4.9	-2.1	-3.9	-2.3	-3.8	-3.4	-4.6	-3.5	-2.5	0.6	-3.4	-5.4	-2.1	-2.6	-0.3	-4.6	-2.5	-4.7
Leg predicted mass (left)	2.3	12.2	29.5	-4.9	-2.1	-4.0	-2.2	-3.8	-3.5	-4.7	-3.6	-2.5	0.5	-3.4	-5.4	-2.2	-2.6	-0.3	-4.6	-2.5	-4.7
Loud music exposure frequency	2.2	2.4	4.8	-1.6	-1.1	-1.8	-1.9	-1.7	-1.3	-1.7	-1.6	-1.0	0.1	-1.3	-2.1	-1.3	-1.6	-0.5	-2.2	-1.6	-1.8
Leg fat-free mass (right)	2.2	11.7	28.2	-4.8	-1.9	-4.0	-2.2	-3.9	-3.6	-4.7	-3.5	-2.2	0.6	-3.3	-5.3	-2.1	-2.4	0.1	-4.4	-2.2	-4.6
Whole body water mass	2.2	12.8	29.8	-5.1	-2.2	-4.1	-2.3	-4.0	-3.6	-4.9	-3.7	-2.4	0.4	-3.6	-5.5	-2.3	-2.5	-0.2	-4.6	-2.5	-4.9
Leg predicted mass (right)	2.2	12.0	29.1	-4.8	-1.9	-4.0	-2.2	-4.0	-3.6	-4.7	-3.5	-2.3	0.7	-3.3	-5.4	-2.2	-2.4	0.0	-4.5	-2.3	-4.7
Basal metabolic rate	2.1	11.6	28.2	-4.9	-2.0	-3.8	-2.2	-3.7	-3.6	-4.6	-3.4	-2.2	0.3	-3.4	-5.3	-2.1	-2.5	0.0	-4.4	-2.4	-4.6
Medication: Co-codamol	2.0	2.4	5.2	1.8	1.8	0.9	2.0	1.0	2.1	1.8	1.1	0.8	0.3	0.9	1.9	2.1	1.1	0.9	1.8	1.1	2.3
Leg pain on walking	2.0	2.6	7.3	1.5	1.2	1.9	0.0	2.5	0.5	2.7	2.5	0.5	-1.2	-0.3	2.0	2.2	-0.2	2.1	1.4	0.4	1.4
Smoking status: Current	2.0	3.2	7.5	2.0	1.6	2.4	1.3	2.2	1.5	2.6	1.7	0.7	0.4	1.8	2.1	2.7	0.7	0.7	1.8	0.7	2.6
Lung FEV1/FVC ratio	1.9	9.5	18.9	3.7	2.4	4.3	2.0	3.9	1.6	4.3	3.6	3.0	1.3	4.2	3.7	1.7	1.6	1.3	3.6	2.2	3.7
Falls in the last year	1.9	2.6	6.4	1.6	2.1	1.0	1.2	1.1	1.1	2.1	1.7	1.5	0.1	1.2	1.7	1.6	1.2	1.9	2.0	1.5	2.5
Ever had bowel cancer screening	1.9	2.2	4.7	2.1	1.2	1.1	1.7	1.1	2.0	1.5	0.7	0.4	0.2	1.6	1.7	1.2	1.5	-0.9	2.0	1.5	2.2
Financial situation satisfaction	1.9	2.3	10.6	1.0	0.5	1.6	-1.6	2.0	0.4	1.7	2.2	-0.9	-3.3	-1.6	0.9	2.1	-0.7	1.9	0.6	-0.1	0.1
Medication: Bendroflumethiazide	1.9	2.9	9.9	2.7	0.7	3.1	0.4	2.8	1.8	2.6	2.0	-0.8	0.4	1.0	1.2	1.9	-1.2	-0.6	0.7	-0.9	1.5
Arm predicted mass (left)	1.9	9.8	23.3	-4.6	-1.6	-3.5	-1.9	-3.5	-3.2	-4.2	-3.1	-2.0	0.3	-3.1	-4.8	-1.8	-2.4	0.3	-4.1	-2.3	-4.2
HbA1C	1.8	2.0	7.5	1.9	-0.1	2.2	-0.5	1.8	2.7	1.8	0.9	-1.0	-1.4	0.1	1.2	2.0	-0.5	-0.8	0.5	-0.8	1.3
Time employed in main current job	1.8	2.1	5.1	2.3	1.7	1.4	0.6	1.7	1.9	2.1	1.3	0.0	-1.3	1.6	1.3	2.1	-0.3	0.8	0.9	0.1	2.0
Exposure to tobacco smoke at home	1.8	2.0	4.1	-1.0	-2.0	-1.0	-1.0	-1.3	0.1	-1.5	-1.6	-1.8	0.2	-1.1	-1.0	-1.5	-1.4	-2.0	-1.7	-1.8	-1.7
Arm fat-free mass (right)	1.8	9.3	21.2	-4.4	-1.5	-3.7	-1.8	-3.7	-2.7	-4.3	-3.4	-2.1	0.3	-3.1	-4.6	-1.5	-2.0	0.1	-3.9	-2.1	-4.0
Heart disease (mother)	1.8	2.2	6.4	2.3	0.7	2.5	-0.1	2.1	1.0	2.5	2.2	-0.4	-0.2	-0.5	1.8	1.9	-0.5	0.4	1.1	-0.4	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.2	5.9	0.7	1.9	-0.5	2.4	-0.5	2.0	0.4	-0.7	0.9	-0.8	1.4	1.5	1.1	2.1	0.5	1.7	2.0	2.4
Arm predicted mass (right)	1.8	9.2	22.0	-4.3	-1.5	-3.7	-1.8	-3.7	-3.0	-4.3	-3.3	-1.8	0.6	-2.9	-4.7	-1.7	-1.9	0.2	-3.9	-1.9	-4.0
Mouth/teeth dental problems: Mouth ulcers	1.8	2.8	6.8	-1.6	-2.2	-0.9	-2.4	-0.2	-0.0	-1.2	-1.0	-2.6	-0.8	-2.4	-1.6	-0.2	-1.8	-1.2	-2.0	-2.2	-2.4
Commuting to job workplace: Cycle	1.8	2.2	7.0	-2.6	-0.3	-0.8	-0.6	-0.0	-2.6	-0.7	0.5	-0.2	-0.5	-2.5	-1.7	-0.8	-1.3	2.4	-1.3	-0.5	-2.2
Fasting Glucose	1.7	2.0	5.9	1.7	-0.7	2.1	-0.3	1.6	2.2	1.8	0.8	0.0	-0.1	1.4	2.1	0.8	0.5	-1.2	1.4	-0.1	2.4
Supplements: Zinc	1.7	1.8	8.0	-0.2	-2.0	-0.6	-1.5	-0.8	1.6	-1.1	-1.8	-2.0	-0.4	-1.8	-0.2	0.7	-0.1	-2.8	-0.8	-1.2	-0.8
Hand grip strength (right)	1.7	4.7	9.3	-2.7	-1.7	-2.9	-1.6	-2.5	-2.4	-2.8	-2.0	-1.3	-1.4	-2.5	-3.1	-1.6	-1.3	0.2	-2.5	-1.3	-2.8
High blood pressure (siblings)	1.7	2.5	7.9	2.8	0.6	2.2	-0.2	2.1	1.0	2.3	2.5	0.4	-0.6	0.5	2.1	1.0	0.8	-0.3	2.1	0.9	1.4
Shortness of breath walking on level ground	1.7	2.0	5.6	2.0	0.0	1.7	-0.6	2.2	2.3	2.4	1.4	-1.2	-0.8	-0.1	1.7	1.9	-1.1	-0.7	0.6	-1.0	0.8
Ever smoked	1.7	3.0	8.8	1.6	2.6	1.1	1.7	1.1	1.1	1.9	1.2	1.3	-0.3	1.1	1.5	3.0	1.6	1.9	2.0	1.9	2.2
Arm fat-free mass (left)	1.7	8.7	21.4	-4.2	-1.4	-3.1	-2.0	-3.2	-3.1	-3.9	-2.7	-2.0	0.1	-3.1	-4.6	-1.7	-2.4	0.5	-3.9	-2.2	-4.1
Impedance of leg (left)	1.6	8.0	17.3	3.3	2.2	3.1	1.4	3.0	1.2	3.6	3.5	2.9	-1.5	2.4	4.2	1.9	2.3	2.0	3.8	2.5	3.6
Happiness	1.6	1.9	5.3	0.8	1.6	0.6	0.4	1.2	0.5	1.7	1.9	1.2	-1.9	0.7	1.8	1.5	0.7	2.3	1.5	1.1	1.4
Medication for cholesterol	1.6	2.4	5.8	-2.4	-1.1	-2.3	-0.5	-1.8	-2.2	-2.0	-1.4	0.2	0.5	-1.1	-2.0	-2.3	-0.1	0.1	-1.3	-0.2	-2.0
Mean Putamen Volume	1.5	1.7	5.0	0.6	1.4	0.3	1.4	0.8	-0.9	1.0	1.7	2.2	1.2	1.2	0.9	-0.3	1.5	1.3	1.7	2.1	1.2
Serious illness, injury or assault to yourself	1.5	1.8	4.5	-1.1	-0.9	-1.3	-1.0	-1.9	-1.3	-2.0	-1.7	-0.1	0.5	-0.9	-2.1	-1.4	-0.5	-1.2	-1.6	-0.8	-1.9
Had other major operations	1.5	1.9	9.9	0.5	0.5	0.5	-0.5	1.9	0.1	1.8	2.0	-0.5	-3.2	-1.3	1.3	1.2	-1.0	2.3	0.4	-0.6	0.2
Illnesses of siblings	1.5	2.1	7.7	-2.2	-0.5	-2.8	0.6	-2.5	-0.4	-2.2	-2.6	-0.3	-0.3	-0.8	-1.6	-0.9	0.2	-0.3	-1.3	-0.1	-1.0
Depression (self-reported)	1.5	1.8	6.1	0.2	-2.4	0.3	-2.5	0.6	1.4	0.2	-0.0	-2.0	-1.6	-2.2	1.0	0.4	-0.0	-2.0	0.2	-0.8	-0.8
Comparative height size at age 10	1.5	8.0	18.2	-4.0	-2.3	-2.9	-2.9	-2.3	-2.4	-3.4	-3.2	-2.0	-1.1	-4.0	-4.1	-0.6	-1.4	-0.4	-3.3	-1.9	-4.3
Medication: Aspirin	1.5	2.0	6.6	0.9	-1.7	1.8	-2.6	0.8	0.1	0.4	0.4	-2.5	-0.7	-0.3	-0.1	0.1	-2.1	-1.8	-1.1	-2.2	-0.6
Knee pain experienced in last month	1.5	2.3	6.0	0.1	2.3	0.8	1.0	1.3	-0.2	1.5	1.9	2.2	-0.4	1.0	1.2	1.0	1.5	2.4	1.9	2.3	1.4
Number of self-reported non-cancer illnesses	1.5	2.6	8.2	-0.3	-2.9	0.4	-2.4	-0.2	-0.8	-0.8	-0.9	-2.2	0.8	-1.5	-1.0	-0.7	-1.8	-2.6	-1.7	-2.3	-2.0
LDL Cholesterol	1.4	2.2	5.1	0.7	1.1	0.7	1.6	1.2	-1.1	1.2	2.1	2.0	0.4	0.5	1.8	0.5	1.7	2.3	2.1	2.0	1.1
Hearing difficulty/problems: Yes	1.4	2.2	4.4	0.9	1.8	0.4	1.9	0.4	0.7	1.2	1.2	1.6	-1.2	1.9	1.9	1.0	1.4	1.8	1.8	1.7	2.1
Mouth/teeth dental problems: Dentures	1.4	2.4	6.1	-1.1	-1.0	0.3	-2.5	-0.0	-1.6	-0.8	-0.1	-1.8	-0.7	-2.0	-2.2	-0.6	-2.4	0.4	-2.2	-2.1	-2.2
Standing height	1.4	14.2	28.5	-5.3	-3.4	-4.2	-3.3	-3.9	-4.1	-5.0	-3.7	-2.7	-1.0	-4.5	-5.1	-2.2	-2.2	-0.6	-4.4	-2.6	-5.2
Ever depressed for a whole week	1.4	1.8	4.2	1.7	1.4	0.9	0.6	1.4	0.2	1.6	1.9	1.1	-0.3	-0.1	1.6	1.5	1.1	2.0	1.7	1.4	1.0
Neuroticism (2016)	1.3	1.9	5.5	-1.6	-1.0	-1.0	-1.4	-1.7	-1.6	-1.8	-1.1	-0.3	-0.0	-0.8	-1.5	-2.4	-1.3	0.1	-1.9	-1.2	-1.5
Triglycerides	1.3	2.2	6.2	1.4	0.6	2.1	1.0	2.4	1.7	2.5	1.6	0.6	0.7	0.8	2.0	1.4	0.7	-0.3	1.9	0.9	1.5
Height	1.3	24.9	49.4	-6.4	-4.2	-5.4	-4.4	-4.6	-5.5	-5.8	-4.2	-4.0	-0.0	-6.4	-7.0	-3.6	-3.9	-1.1	-6.1	-4.0	-7.0
Past tobacco smoking	1.3	2.3	5.5	-2.0	-2.3	-1.5	-1.1	-1.3	-0.8	-1.9	-1.5	-1.1	0.3	-1.0	-1.1	-2.3	-0.7	-1.9	-1.5	-1.3	-1.9
Allergy	1.3	2.9	13.1	1.0	2.8	1.7	0.9	1.6	-1.4	2.0	2.7	1.9	-0.1	1.9	0.4	0.6	-0.4	3.6	0.9	0.8	1.4
Weight	1.3	6.4	17.3	-3.5	-1.2	-2.6	-1.7	-2.6	-2.9	-3.3	-2.2	-1.8	0.4	-2.4	-4.2	-1.3	-2.3	0.2	-3.5	-2.1	-3.4
Birth weight	1.3	2.9	7.3	-2.1	-0.3	-2.7	0.2	-2.6	-1.8	-2.3	-2.1	-0.4	0.1	-1.1	-2.6	-1.9	-0.9	-0.2	-2.0	-0.9	-1.7
Neck or shoulder pain in last month	1.3	1.9	5.7	1.6	0.7	0.1	1.4	-0.0	2.4	0.7	-0.1	0.4	1.1	1.2	2.3	1.6	1.8	-0.1	1.7	1.3	2.0
Guilty feelings	1.3	1.9	6.5	-1.7	-0.3	-2.3	-0.1	-2.1	-2.5	-1.6	-0.5	1.5	-0.1	0.8	-0.5	-1.6	0.6	2.4	-0.3	0.7	-0.1
Cholesterol lowering medication	1.3	1.9	6.5	2.6	1.5	1.7	0.3	1.3	2.2	1.6	0.7	-0.4	-0.0	1.1	1.2	2.2	-0.1	-0.6	0.8	-0.0	2.1
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	4.6	-0.4	-1.3	-0.6	-0.6	-1.0	1.2	-0.8	-1.9	-1.8	-0.1	-2.1	-0.3	0.6	-1.1	-2.0	-1.4	-2.0	-1.0
Average weekly spirits intake	1.2	1.5	5.0	-0.9	-0.9	-1.0	-0.1	-1.7	-0.1	-1.7	-2.2	-0.8	1.6	-0.3	-1.4	-1.0	-0.5	-1.7	-1.5	-0.9	-0.9
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	5.1	-0.4	-1.7	-0.1	-1.3	-0.4	0.7	-0.5	-1.4	-2.0	-0.2	-0.8	-0.3	0.0	-1.6	-2.3	-1.4	-2.2	-1.0
Impedance of leg (right)	1.2	6.0	13.7	2.8	1.6	2.8	1.4	2.8	1.1	3.2	3.0	2.4	-1.5	2.1	3.7	1.5	2.0	1.3	3.3	2.1	3.1
Hip circumference	1.2	5.0	11.3	-3.0	-1.7	-1.7	-1.3	-2.1	-2.4	-2.9	-1.7	-1.8	-0.1	-2.3	-3.4	-1.4	-2.4	-0.2	-3.2	-2.3	-3.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	3.8	1.8	1.5	0.1	1.6	0.2	1.1	0.8	0.4	1.8	-0.1	1.6	1.8	1.0	1.7	0.5	1.7	1.7	1.9
Medication: Amlodipine	1.2	1.7	4.9	1.7	-0.1	1.9	0.1	1.0	1.6	1.4	0.9	0.1	-1.3	1.6	2.2	1.1	0.8	-1.0	1.6	0.6	1.7
Medication: Aspirin	1.2	1.6	5.3	1.2	-1.6	1.5	-2.2	0.5	0.6	0.2	0.1	-2.3	-0.8	-0.2	0.1	0.5	-1.5	-2.0	-0.8	-1.8	-0.4
Alzheimer’s Disease (including proxy)	1.1	1.6	6.4	-0.1	1.0	-0.6	1.8	-0.4	-0.0	-0.0	-0.2	2.5	0.9	1.8	0.3	-0.9	2.1	0.1	1.4	2.2	1.0
Number of treatments/medications taken	1.1	2.0	6.3	0.6	-1.9	0.5	-2.5	-0.1	0.7	-0.4	-0.4	-2.4	-0.7	-1.6	0.1	0.4	-1.9	-2.0	-1.4	-2.5	-0.8
Relative age of first facial hair	1.1	2.2	7.3	1.8	1.4	1.2	0.3	1.9	2.4	2.2	1.4	-0.0	-1.2	-0.5	1.7	2.7	-0.2	0.7	1.0	-0.1	1.8
Ever used hormone-replacement therapy (HRT)	1.1	1.4	3.2	1.3	1.2	1.6	1.1	1.4	1.5	1.7	0.7	0.3	1.1	0.3	1.2	1.8	0.6	-0.6	1.2	0.6	1.5
Vitamin and mineral supplements	1.1	1.5	6.1	1.1	0.9	1.5	-0.2	1.8	-0.3	1.8	2.5	0.8	0.3	1.1	0.7	0.7	-0.3	2.1	1.1	0.8	1.1
Hearing difficulty/problems with background noise	1.1	1.8	6.6	0.0	1.4	-0.3	1.8	0.3	-0.7	0.9	1.7	2.0	-1.0	0.8	1.7	-0.1	1.2	2.6	1.6	1.7	1.2
Pulse wave reflection index	1.1	1.3	3.5	-1.1	-0.3	-1.3	-0.5	-1.5	-0.9	-1.5	-1.5	-0.7	0.7	-0.6	-1.9	-1.1	-1.0	-0.6	-1.7	-1.1	-1.0
Medication: Allopurinol	1.1	1.5	4.0	-0.2	-1.5	-0.9	-1.1	-1.3	0.0	-1.2	-1.3	-1.3	0.2	-1.4	-1.5	-0.8	-1.1	-2.0	-1.5	-1.5	-1.5
Hearing aid user	1.1	1.2	3.6	0.8	0.0	1.7	-0.9	1.6	1.4	1.5	1.2	-0.9	-1.8	-0.5	1.0	1.9	-0.3	0.3	0.6	-0.4	0.5
Pain type(s) experienced in last month: Hip pain	1.1	1.4	4.1	1.3	0.4	1.7	-0.5	2.0	1.5	1.9	1.6	-0.3	-0.3	0.7	1.6	1.1	0.1	0.3	1.2	0.3	0.9
Impedance of whole body	1.1	5.5	12.7	3.1	1.3	2.7	0.9	2.7	1.6	3.2	2.7	1.7	-1.6	1.6	3.6	2.0	2.0	0.8	3.2	1.9	3.1
Alzheimer’s Disease (in father)	1.0	1.1	4.8	-0.2	0.6	0.1	1.7	-0.1	-0.8	-0.1	-0.1	2.2	1.2	1.0	0.1	-1.1	1.8	0.3	1.1	1.7	0.5
Age at First Birth	1.0	1.5	3.9	1.4	-0.5	1.6	-1.2	2.0	0.9	1.7	1.8	-1.2	-1.3	-0.2	0.9	1.7	-1.3	0.6	0.2	-1.1	0.2
Body Mass Index (BMI) (2010)	1.0	1.4	4.1	0.3	1.0	0.3	1.6	0.1	-0.6	0.3	-0.1	1.8	2.0	2.0	0.5	-0.3	1.7	-0.9	1.2	1.5	1.3
Type 2 Diabetes (T2D) (2012)	1.0	1.1	2.9	1.3	0.7	1.4	0.5	1.2	1.7	1.2	0.5	0.9	0.4	1.3	0.8	1.3	1.3	-0.6	1.3	0.8	1.0
Blood Platelet Count	1.0	11.1	35.3	3.6	0.8	5.9	-0.8	5.9	2.5	5.2	5.1	-0.7	-3.5	-0.0	3.8	3.7	-0.9	2.0	2.5	-0.2	2.0
Fed-up feelings	1.0	1.9	7.7	-1.7	-0.7	-1.1	-1.8	-1.1	-2.8	-1.1	0.3	-0.1	-0.2	0.0	-1.4	-2.0	-1.6	1.8	-1.5	-0.9	-1.3
Number of incorrect matches in round	1.0	1.7	3.8	-1.0	-1.3	-0.4	-1.6	-0.9	-1.4	-1.1	-0.5	-1.4	-1.4	-1.6	-1.1	-0.7	-1.9	0.1	-1.9	-1.8	-1.6
Financial difficulties in last 2 years	1.0	1.3	2.9	1.1	1.0	0.7	0.6	0.4	1.2	1.1	0.8	1.0	-0.7	0.8	1.3	1.5	1.7	-0.0	1.7	1.6	1.7
Noisy workplace	1.0	1.2	4.2	1.5	-0.5	0.9	-0.3	1.5	1.7	1.5	0.6	-1.3	-1.5	-0.7	1.3	2.0	-0.0	-0.5	0.7	-0.4	0.5
Medication: Lansoprazole	1.0	1.1	2.3	1.3	1.0	1.5	0.9	1.1	-0.1	1.2	1.1	0.9	-0.3	0.9	1.2	1.5	0.5	1.4	1.0	0.7	1.1
Commuting to job workplace: Walk	1.0	1.1	4.1	-1.4	-0.3	-0.3	-0.5	-0.0	-1.2	-0.3	0.8	-0.2	-2.0	-0.8	-0.9	-1.5	-1.3	1.6	-0.9	-0.7	-1.3
Illnesses of father: High blood pressure	1.0	1.3	4.5	0.9	0.7	-0.1	2.1	0.2	0.5	0.6	0.6	1.0	-1.1	0.7	1.5	1.2	1.7	0.8	1.6	1.6	1.2
Number of operations (self-reported)	1.0	1.5	4.2	-0.6	-1.4	-0.3	-1.5	-0.0	-0.5	-0.4	-0.6	-2.1	-1.9	-1.6	-0.6	0.2	-1.7	-0.7	-1.4	-1.9	-1.0
Age started oral contraceptive pill	1.0	1.2	4.0	1.2	0.3	1.1	0.1	1.6	0.5	1.6	2.0	0.2	-1.4	0.9	1.6	0.9	0.0	0.9	1.2	0.4	0.8
Crohns Disease (2012)	0.9	1.4	4.6	1.9	0.4	1.2	0.8	1.9	2.2	1.7	0.7	-0.7	-1.1	-0.7	1.2	1.6	-0.3	-1.1	0.6	-0.5	0.5
Waist Hip Ratio (WHR)	0.9	4.0	11.5	1.9	2.8	2.0	0.4	2.5	-1.1	3.0	3.4	1.6	0.2	1.5	1.4	1.6	0.2	2.9	1.9	1.4	2.2
Diabetes (mother)	0.9	1.2	2.7	-1.1	-1.6	-0.8	-1.6	-0.9	-0.7	-1.2	-1.1	-0.6	1.3	-1.3	-1.1	-0.5	-0.3	-0.8	-1.0	-0.7	-1.6
Maternal smoking around birth	0.9	1.3	3.6	1.0	0.5	1.3	-0.3	0.7	-0.2	0.7	1.7	1.2	-1.4	0.8	1.3	0.4	1.3	1.9	1.5	1.8	0.7
Multivitamins +/- minerals	0.9	1.2	4.9	-0.2	0.1	-1.3	1.0	-1.5	1.5	-1.1	-2.2	0.3	0.7	-0.4	0.3	-0.2	1.5	-2.2	0.2	0.4	-0.0
Chronic bronchitis/emphysema (father)	0.9	1.1	3.4	-1.1	-0.4	-1.7	-0.7	-1.9	-1.0	-1.8	-1.0	0.0	-0.7	-0.7	-0.8	-1.8	-0.2	0.2	-1.0	-0.2	-0.8
Medication: Paracetamol	0.9	1.6	7.3	1.4	0.6	0.1	0.8	0.0	2.6	0.7	-0.6	-1.1	-1.0	0.5	1.4	2.7	0.1	-0.6	0.4	-0.3	2.2
Medication: Omeprazole	0.9	1.0	3.5	-0.1	-0.8	-0.0	-0.2	-0.1	1.4	0.2	-0.9	-1.8	-0.7	-1.8	0.3	1.0	-1.4	-1.1	-1.0	-1.9	-0.3
Medication: Seretide 50 evohaler	0.9	1.0	3.8	0.2	-1.3	1.9	-1.7	1.4	-0.6	0.6	1.3	-0.6	-1.3	-1.1	0.3	-0.5	-0.8	0.5	-0.1	-0.7	-0.8
Mean time to correctly identify matches	0.9	1.7	5.6	-0.8	-2.4	-1.5	-1.6	-1.2	-0.6	-1.7	-1.4	-1.1	-0.8	-1.6	-0.6	-1.1	-0.4	-1.5	-1.1	-1.1	-1.6
Commuting to job workplace: Car/motor vehicle	0.9	1.0	4.2	1.1	-0.1	0.2	0.1	0.1	2.0	0.5	-0.5	-0.6	0.2	1.4	1.4	1.3	0.6	-1.7	0.7	0.0	1.6
Qualifications: nursing, teaching	0.9	1.4	5.9	-1.5	0.6	-2.4	1.1	-2.3	-0.7	-1.6	-1.7	1.0	0.3	0.5	-0.8	-0.6	0.7	0.8	-0.6	0.7	-0.2
Fractured/broken bones in last 5 years	0.9	1.2	2.8	-1.4	-0.6	-1.1	-0.9	-0.4	-1.7	-0.5	-0.3	-0.9	0.7	-1.6	-1.5	-0.3	-1.5	0.2	-1.4	-1.3	-1.5
Alcohol drinker status: Previous	0.9	1.0	3.3	0.9	0.3	-0.3	0.4	-0.6	1.5	-0.2	-0.9	0.3	-1.3	0.9	0.8	1.3	1.8	-0.9	1.1	1.3	1.0
Major Depression (MDD)	0.8	1.0	2.5	0.4	1.4	0.2	0.9	0.4	-0.4	0.9	1.0	1.6	-0.7	0.7	1.0	0.2	1.4	1.4	1.4	1.4	1.0
Schizophrenia (2014)	0.8	1.9	9.2	-1.8	-0.3	-2.3	-1.2	-1.1	-0.2	-1.3	-1.7	-0.5	-1.7	-3.0	-1.2	0.4	0.2	0.4	-0.8	-0.3	-1.7
Hand grip strength (left)	0.8	2.0	4.3	-1.9	-0.7	-1.8	-1.3	-1.6	-1.4	-1.7	-1.1	-0.7	-1.9	-2.1	-1.9	-1.1	-0.6	0.8	-1.4	-0.5	-1.8
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	2.5	0.6	-0.1	1.5	-0.9	1.2	0.6	1.2	0.7	-1.6	-1.1	-0.4	-0.0	0.6	-1.5	-0.7	-0.4	-1.1	0.4
Hayfever, allergic rhinitis or eczema	0.8	1.7	7.8	-0.3	-2.0	-1.2	-0.6	-1.1	1.5	-1.3	-2.3	-1.5	-1.0	-1.6	-0.0	-0.3	0.2	-2.8	-0.6	-0.6	-0.9
Tense / ‘highly strung’	0.8	1.3	3.9	-1.4	-1.6	-0.1	-2.0	-0.6	-0.8	-1.2	-0.8	-1.1	-0.2	-1.7	-1.0	-0.9	-0.8	-0.3	-1.3	-1.1	-1.5
Hair/balding pattern: Pattern 4	0.8	1.9	5.7	-1.8	-1.6	-1.9	-0.3	-2.4	-1.2	-2.1	-2.3	-0.7	0.4	-0.5	-1.0	-1.2	-0.4	-0.1	-1.5	-0.8	-1.4
Blood clot in the leg (DVT)	0.8	1.1	4.5	-0.7	-1.1	-0.6	-0.8	-0.9	0.6	-1.2	-1.6	-1.0	0.6	-0.7	-1.0	-0.3	-0.6	-2.1	-1.1	-1.2	-1.1
Medication for pain relief, constipation, heartburn	0.8	1.3	4.6	-1.4	0.7	-0.9	1.6	-0.2	-1.2	-0.5	0.3	2.1	0.1	0.6	-0.3	-1.5	1.7	1.2	0.9	2.0	-0.5
Migraine (self-reported)	0.8	1.0	5.8	-0.5	-0.6	-1.2	-0.8	-0.9	1.3	-0.8	-1.1	-1.1	-0.7	-2.4	-0.5	0.2	-0.5	-0.7	-0.9	-0.9	-1.2
Average weekly champagne plus white wine intake	0.8	1.0	3.1	0.0	1.6	-0.5	0.9	-0.4	0.0	0.3	0.4	1.4	-0.6	0.4	0.8	0.2	1.5	1.8	1.2	1.7	1.2
Medication: Paracetamol	0.8	1.3	5.0	0.9	-0.3	-0.1	-0.2	-0.3	2.1	-0.1	-1.2	-2.0	-1.3	-0.6	0.5	2.2	-0.9	-0.9	-0.7	-1.4	1.0
Schizophrenia (2018)	0.7	1.4	5.3	-1.3	-0.1	-2.3	-0.4	-1.4	0.1	-1.4	-2.1	0.3	-1.0	-2.1	-0.8	0.6	1.1	-0.1	-0.3	0.3	-1.2
Alzheimer’s Disease (in mother)	0.7	0.9	1.8	0.8	1.0	0.1	0.9	0.6	0.8	1.0	0.8	1.3	0.0	1.3	0.7	0.5	1.0	0.2	1.3	1.2	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	5.9	-0.5	-0.4	0.2	-2.2	-0.4	-2.4	-0.6	1.0	0.2	0.1	-0.0	-0.9	-0.5	-0.5	1.4	-0.4	0.1	-0.4
Relative age voice broke	0.7	1.1	3.3	0.8	1.1	1.7	-0.1	1.6	0.6	1.6	1.8	0.5	-0.4	-0.4	0.7	0.5	-1.3	1.6	0.0	-0.6	0.6
Had menopause	0.7	0.8	3.5	-0.1	-0.8	0.1	0.1	-0.9	-0.2	-0.8	-0.6	0.7	1.6	1.8	-0.1	-1.9	0.5	-1.5	0.1	0.4	0.0
Impedance of arm (right)	0.7	3.1	8.0	2.1	0.4	2.5	0.0	2.6	0.4	2.7	2.8	1.1	-1.2	1.4	2.4	0.9	0.8	0.4	2.2	1.0	2.0
Worrier / anxious feelings	0.7	1.2	3.9	-1.5	-1.2	-1.6	-0.5	-1.5	-1.7	-1.4	-0.3	0.2	-1.2	-0.2	-0.2	-2.0	-0.5	0.8	-0.9	-0.4	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.9	0.8	1.0	1.2	-0.1	0.8	-0.6	1.1	1.6	0.4	0.3	1.0	0.9	0.7	-0.3	1.7	0.7	0.4	1.5
Peak expiratory flow (PEF)	0.7	1.6	8.0	0.4	1.4	0.7	0.5	1.1	-0.8	1.3	2.0	1.6	-1.1	0.3	0.8	0.7	0.7	2.8	1.3	1.3	0.9
Gout (self-reported)	0.7	1.0	2.2	-0.2	-1.1	-0.4	-0.7	-1.0	0.2	-1.0	-0.9	-0.9	-0.6	-1.1	-1.2	-0.8	-1.3	-1.5	-1.4	-1.4	-1.3
Mouth/teeth dental problems: Loose teeth	0.7	0.8	3.6	-0.7	0.5	-0.8	0.9	-1.2	-0.5	-0.8	-0.5	0.9	1.8	1.9	-0.3	-1.1	0.5	-0.2	-0.1	0.3	0.4
Family relationship satisfaction	0.7	0.9	1.6	1.2	1.0	0.0	1.1	0.8	0.9	1.2	0.5	0.5	-0.8	0.6	1.1	1.3	0.9	0.1	1.3	0.9	1.2
Back pain experienced in last month	0.7	1.1	2.0	0.7	1.1	0.9	0.4	1.3	1.3	1.4	1.2	0.9	1.3	0.5	1.1	1.4	0.5	0.3	1.1	0.5	1.4
Osteoarthritis (self-reported)	0.7	0.9	3.4	0.6	1.0	1.1	0.3	0.5	1.1	0.7	0.1	0.3	1.8	1.2	0.5	1.3	0.6	-1.3	0.7	0.6	1.4
Irritability	0.7	1.2	6.1	0.1	1.0	0.4	0.8	0.6	-1.1	0.8	1.7	1.8	-0.2	0.3	1.0	0.0	0.8	2.5	1.1	1.4	0.7
Heart disease (siblings)	0.7	0.9	2.0	-0.4	-0.9	0.3	-1.4	0.7	-1.4	0.1	1.1	-1.0	-0.9	-1.0	-0.5	-0.2	-1.4	0.8	-0.8	-1.1	-1.3
Verbal and Numeric Reasoning (VNR)	0.6	1.5	7.2	-1.2	0.0	-1.0	0.1	-1.0	-2.7	-1.2	0.5	1.5	1.4	0.5	-0.7	-1.7	1.2	1.6	0.5	1.6	-0.7
Bipolar Disorder (2011)	0.6	0.6	2.6	-0.3	-0.2	0.5	-0.6	0.0	0.1	-0.3	-0.3	-0.9	0.4	-0.6	-0.8	-0.4	-1.6	-0.0	-1.3	-1.4	-0.8
Systolic Blood Pressure	0.6	3.0	9.1	3.0	-0.4	1.9	0.5	1.8	0.5	1.8	2.2	-0.7	-2.7	1.3	2.7	2.0	0.5	0.7	1.8	0.5	2.2
Diabetes (father)	0.6	0.7	1.8	0.8	0.0	1.2	0.0	1.3	1.0	1.1	1.0	-0.2	-1.3	-0.5	1.2	0.9	0.4	-0.1	0.9	0.1	0.5
Sitting height	0.6	4.1	9.2	-3.0	-1.4	-2.8	-1.3	-2.3	-2.0	-2.8	-2.3	-1.5	-1.2	-2.6	-2.7	-0.7	-0.5	-0.1	-2.1	-0.8	-2.6
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	3.6	-0.8	-1.7	-0.3	-1.9	-0.4	-0.9	-0.4	0.4	-1.0	-1.4	-1.1	-0.2	-0.1	-0.9	0.8	-0.6	-0.8	-1.1
Mouth/teeth dental problems	0.6	1.0	2.6	1.2	0.7	0.4	1.6	0.8	0.5	1.3	0.6	1.0	0.9	0.7	1.1	0.4	1.0	-0.5	1.4	1.1	1.4
Heart attack	0.6	0.8	2.0	1.4	-0.9	1.0	-0.8	0.9	1.2	0.8	0.5	-1.0	-0.9	0.3	1.3	0.9	-0.2	-1.0	0.5	-0.3	0.6
Fluid intelligence score	0.6	1.3	6.5	-1.5	-0.1	-1.2	-0.2	-1.1	-2.6	-1.2	-0.1	1.2	1.4	-0.2	-1.0	-1.7	0.8	0.9	-0.0	0.9	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	3.9	0.1	0.6	-0.2	0.1	0.0	2.0	0.5	-0.4	-0.1	-0.8	0.6	1.2	0.8	0.6	-1.2	0.6	0.3	1.2
Impedance of arm (left)	0.6	2.9	7.3	2.3	0.3	2.0	0.5	2.1	1.3	2.4	1.9	0.9	-1.2	1.2	2.7	1.4	1.4	-0.3	2.4	1.2	2.2
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.6	-0.1	-1.3	-0.2	-0.6	-0.3	0.1	-0.9	-1.3	-1.1	-1.6	-1.3	-0.4	-0.2	0.0	-1.5	-0.6	-0.5	-0.9
Age at last live birth	0.6	0.9	2.5	-0.3	-0.4	0.7	-1.6	1.0	-1.1	0.4	1.0	-0.9	-1.4	-1.1	-0.6	0.1	-1.4	0.7	-0.8	-1.2	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	3.0	-0.6	-0.9	-0.4	-0.8	-0.3	0.4	-0.6	-0.9	-1.1	-1.4	-1.7	-0.4	0.3	-0.7	-0.1	-0.9	-1.1	-0.8
Smoking status: Previous	0.6	0.8	2.2	1.4	1.5	0.8	0.4	0.7	0.5	1.1	1.0	0.8	-0.3	0.5	0.5	1.1	0.4	1.2	0.9	0.8	1.2
Average weekly red wine intake	0.6	0.9	3.2	0.7	-1.8	0.8	-1.0	1.1	1.2	0.5	-0.4	-1.2	-0.4	-0.9	0.6	0.5	-0.2	-1.8	0.0	-0.8	-0.9
Eye problems/disorders: Cataract	0.6	0.7	1.7	0.7	-0.3	1.0	-1.2	0.8	1.3	0.8	0.5	-1.1	-0.8	-0.9	0.6	1.2	-0.7	0.0	0.0	-0.7	0.0
Tinnitus: Yes, now most or all of the time	0.6	0.7	3.3	-0.4	-0.8	0.6	-0.5	0.5	1.4	0.2	-0.8	-1.0	-0.8	-1.8	-0.1	0.7	-0.1	-1.2	-0.3	-0.7	-0.9
Commuting to job workplace: Public transport	0.6	0.8	2.4	0.5	1.1	1.1	0.1	1.5	0.2	1.3	1.2	1.2	0.3	0.3	0.4	0.4	0.8	0.3	1.2	1.1	0.4
Eye problems/disorders: Glaucoma	0.6	0.7	2.0	0.6	0.3	1.3	0.7	1.4	0.2	1.3	1.4	0.4	0.5	0.9	0.9	-0.7	-0.4	-0.2	0.6	-0.2	0.8
High cholesterol (Self-reported)	0.6	1.0	3.5	1.6	0.0	0.9	-0.3	0.8	1.7	0.9	0.1	-1.1	-0.6	0.3	0.9	1.6	-0.1	-1.9	0.4	-0.4	1.0
Unable to work because of sickness or disability	0.6	0.8	2.0	1.3	0.1	0.8	-0.7	1.2	1.3	1.3	0.5	-0.4	-0.9	0.2	1.0	1.4	-0.5	-0.6	0.3	-0.8	0.8
Pain experienced in last month	0.6	1.1	2.9	-0.2	-0.9	0.2	-1.7	-0.0	-1.3	-0.6	0.0	-0.8	-0.6	-0.3	-1.6	-1.6	-1.4	-0.4	-1.3	-1.3	-1.4
Heart attack/myocardial infarction (self-reported)	0.6	0.7	2.2	1.5	-0.8	1.0	-0.6	0.8	1.2	0.8	0.6	-0.7	-0.6	0.5	1.4	0.8	0.2	-1.0	0.8	-0.0	0.7
Neuroticism (Nagel 2018)	0.5	1.2	4.3	-0.4	0.0	-1.2	0.4	-1.1	-1.0	-0.4	0.3	2.1	0.1	1.6	1.0	-1.3	1.4	1.5	1.0	1.5	0.8
Coronary Artery Disease (CAD)	0.5	0.5	2.1	0.6	0.0	1.0	0.6	1.0	0.2	0.9	1.5	0.1	-1.3	0.5	1.0	0.3	-0.1	0.6	0.6	0.0	0.4
Blood White Count	0.5	3.6	13.4	1.3	-0.3	3.7	-1.8	3.5	-1.9	2.4	3.4	-0.9	-0.0	-0.5	0.2	0.5	-2.6	1.3	-0.3	-1.8	-0.3
BMI	0.5	2.6	6.5	-2.0	-0.6	-1.6	-0.4	-2.1	-2.5	-2.5	-1.3	-0.1	1.0	-0.7	-2.5	-2.0	-1.0	0.3	-2.1	-0.8	-1.9
Angina	0.5	0.6	2.5	0.2	-1.6	0.0	-1.3	-0.0	0.1	-0.1	-0.3	-1.4	-0.5	-1.2	0.1	0.4	-0.6	-1.0	-0.5	-1.0	-0.7
Medication for hormone replacement therapy	0.5	0.6	3.0	0.8	0.3	0.6	0.6	1.0	1.7	1.1	0.2	-0.2	0.4	-0.6	0.7	0.9	0.4	-0.9	0.7	0.1	0.5
Taking other prescription medications	0.5	0.7	1.5	0.4	-0.6	1.0	-1.2	0.7	1.0	0.6	0.1	-0.9	-1.2	-1.2	0.6	0.5	-0.8	-1.2	-0.2	-1.1	-0.3
Age when periods started (menarche)	0.5	1.2	3.6	1.3	-1.1	1.9	-0.3	1.5	0.8	1.5	0.8	-1.3	-1.3	0.2	0.8	1.3	-0.8	-0.7	0.3	-1.0	0.7
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.8	0.8	0.7	0.6	0.2	0.6	1.1	0.5	0.4	0.2	-1.3	0.5	1.1	1.0	0.8	0.5	0.9	0.7	0.8
Stomach or abdominal pain in last month	0.5	0.7	2.5	-0.1	-0.3	0.6	-0.8	1.0	0.5	1.1	0.7	-0.8	-1.2	-1.6	0.8	0.9	-0.7	0.4	-0.1	-0.9	-0.4
Pain all over the body in last month	0.5	0.5	2.4	0.2	0.8	0.3	1.6	0.1	-0.8	0.2	0.2	1.3	0.7	0.6	0.1	0.2	0.6	1.1	0.4	0.6	0.4
Medication: Simvastatin	0.5	0.7	2.5	1.5	-0.2	1.0	-1.6	0.6	0.7	0.4	0.5	-1.0	-1.1	-0.4	0.4	0.6	-0.7	-1.1	-0.1	-0.9	0.1
Pulse rate	0.5	0.8	2.4	1.3	0.9	1.0	1.0	1.0	0.9	1.3	0.6	0.1	-1.2	0.3	0.8	1.6	0.1	0.3	0.7	0.3	1.0
Asthma	0.5	1.0	4.6	-0.2	-1.9	0.4	-0.9	0.9	0.8	0.2	0.3	-1.6	-0.9	-2.1	0.5	0.2	-0.5	-1.3	-0.1	-1.0	-1.0
Prospective memory result	0.5	0.6	2.6	0.4	-1.1	0.2	-1.6	0.3	0.9	-0.0	-0.1	-0.8	-1.3	-1.4	0.3	0.9	-0.0	-0.4	-0.1	-0.5	-0.9
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	7.6	-1.0	1.8	-0.2	1.1	0.1	-0.4	0.1	0.4	0.9	-0.0	-0.8	-0.6	0.2	0.1	2.8	-0.0	0.9	-0.0
Worry too long after embarrassment	0.5	0.8	2.5	-1.4	-1.0	-1.6	-0.9	-1.2	-1.5	-1.0	0.1	0.3	0.2	-0.4	-0.3	-1.3	-0.0	0.8	-0.3	-0.0	-0.6
Age at first live birth	0.5	1.0	2.5	-0.5	-0.6	0.8	-1.1	1.6	-1.2	0.8	1.6	-0.4	-1.3	-0.4	0.1	0.1	-1.3	1.3	-0.4	-1.0	-1.0
Medication: Blood pressure	0.5	0.9	6.8	1.1	-1.8	0.2	-1.0	-0.5	-0.1	-0.3	-0.1	-1.0	0.5	1.2	0.3	-0.7	-0.4	-2.6	-0.1	-0.9	0.2
Angina (self-reported)	0.5	0.6	2.8	0.3	-1.7	-0.1	-1.2	-0.2	0.3	-0.3	-0.5	-1.4	-0.3	-1.2	0.2	0.3	-0.4	-1.4	-0.4	-0.8	-0.6
Leg fat mass (right)	0.5	1.8	6.2	-1.8	-0.0	-1.1	-0.7	-1.3	-1.8	-1.6	-0.9	-0.6	0.7	-0.7	-2.5	-0.6	-1.6	0.4	-2.1	-1.4	-1.5
Number of full sisters	0.5	0.6	1.8	0.6	0.7	0.8	0.2	0.7	0.9	0.6	0.3	0.3	-0.0	0.3	1.0	1.3	1.1	0.3	1.1	1.0	1.0
Chest pain or discomfort	0.5	0.7	2.3	0.3	-1.5	-0.3	-1.3	0.2	1.1	0.0	-0.2	-1.2	-1.3	-0.9	1.0	0.4	-0.1	-1.5	0.0	-0.7	-0.4
Long-standing illness, disability or infirmity	0.5	0.7	3.2	0.7	-0.1	1.5	-0.9	0.9	0.8	1.0	0.4	-0.5	-1.8	0.1	1.0	0.9	-0.7	-0.2	0.0	-0.9	0.5
Asthma (self-reported)	0.5	0.9	3.3	-0.0	-1.8	0.5	-0.6	0.9	1.1	0.3	0.2	-1.5	-1.0	-1.7	0.8	0.2	-0.2	-1.5	0.1	-0.8	-0.7
Osteoporosis (self-reported)	0.5	0.6	2.3	-0.2	0.7	-0.8	1.2	0.1	-1.0	0.5	0.9	1.5	-0.0	0.7	0.4	-0.3	0.6	1.4	0.7	0.7	0.5
Medication: Blood pressure	0.5	1.0	3.2	1.7	0.6	1.8	0.2	0.9	1.0	0.9	1.0	0.1	-0.9	1.1	1.3	1.3	-0.2	0.7	0.6	0.0	1.2
Alcohol drinker status: Never	0.5	0.6	2.0	-0.8	-1.4	-0.4	-0.4	-0.5	0.5	-0.9	-0.8	-0.7	0.3	-0.3	-0.3	-1.1	-0.6	-1.3	-0.9	-1.0	-1.0
Average weekly beer plus cider intake	0.5	0.7	4.7	-0.8	-0.7	-0.2	-0.2	-0.5	-2.2	-0.9	0.4	0.4	0.5	0.4	-0.8	-1.5	-0.3	1.1	-0.5	0.0	-0.7
Supplements: Calcium	0.5	0.5	1.8	0.3	-0.6	-0.7	0.1	-0.5	1.0	-0.3	-1.3	0.0	-0.7	-0.2	0.7	1.3	1.0	-1.1	0.4	0.2	0.3
Bipolar Disorder (2018)	0.4	0.7	2.7	-0.1	0.2	0.2	-0.3	0.6	-0.8	0.2	0.5	0.1	1.6	0.3	-1.1	-1.3	-1.5	0.4	-0.9	-0.7	-0.8
Depressed Affect (Nagel 2018)	0.4	0.8	3.6	0.5	0.1	-0.4	0.1	-0.6	0.1	0.1	0.4	1.3	0.5	1.9	1.3	-0.3	1.2	0.7	1.2	1.4	1.4
Depression (Nagel 2018)	0.4	0.6	3.1	0.2	-0.3	0.4	-1.3	0.2	-1.8	0.1	1.5	0.5	-0.0	0.3	-0.0	-0.7	-0.2	1.4	0.3	0.3	0.0
Schizophrenia vs Biploar Disorder	0.4	0.6	2.5	-1.0	-0.2	-1.6	-0.5	-1.0	0.5	-0.6	-0.9	0.1	-1.5	-0.8	0.2	0.5	0.7	0.1	-0.0	0.1	0.0
Crohns Disease (2017)	0.4	0.9	3.0	0.6	1.1	0.9	0.7	1.7	1.7	1.6	0.6	-0.1	-0.0	-1.1	0.7	1.3	-0.4	-0.4	0.4	-0.3	0.5
Ovarian Cancer	0.4	0.5	3.7	-0.6	0.9	-0.0	0.7	-0.3	-0.2	-0.2	0.6	0.2	-1.9	0.5	0.1	-0.1	-0.1	1.5	0.1	0.5	0.5
Blood Red Count	0.4	3.7	36.6	-0.6	-0.5	-0.6	-0.8	-0.9	-2.8	-0.9	-0.1	-0.3	6.1	0.4	-2.3	-1.8	-1.7	-0.7	-1.7	-1.5	-1.0
Heel T-Score	0.4	3.2	29.0	1.6	0.9	1.0	-0.9	1.0	5.4	1.1	-0.9	-2.5	0.5	-1.2	0.3	2.8	0.4	-1.8	0.5	-0.4	1.1
Allergy or Eczema	0.4	1.0	4.4	0.1	-1.2	-1.1	0.3	-0.9	1.6	-0.9	-2.1	-0.5	0.1	-1.1	0.4	0.0	0.8	-2.0	-0.2	0.0	-0.4
Systolic blood pressure, automated reading	0.4	1.1	3.5	1.9	-0.6	1.4	-0.2	1.4	0.6	1.2	1.4	-0.6	-1.1	1.0	1.5	0.9	-0.3	-0.5	0.8	-0.2	1.4
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.6	0.9	0.8	0.0	0.6	0.0	1.0	0.5	-0.1	-0.0	0.5	0.1	0.7	1.3	0.7	-0.2	0.8	0.3	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	5.5	0.5	0.6	0.5	-0.9	1.0	1.3	1.0	0.4	-1.3	-0.0	-2.4	0.2	1.9	0.1	0.8	0.4	0.1	0.0
Alcohol usually taken with meals	0.4	0.7	3.5	0.7	-0.2	-0.3	0.6	-0.2	1.7	0.3	-0.9	-0.5	1.4	-0.3	0.3	1.0	0.4	-1.9	0.3	-0.1	0.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.2	-0.1	-0.9	-1.1	-0.6	-1.2	0.1	-0.8	-1.1	-0.3	0.3	-0.4	0.0	-0.6	0.5	-1.5	-0.1	0.2	-0.3
Alcohol intake versus 10 years previously	0.4	0.6	2.9	1.1	1.0	1.0	0.3	0.9	1.0	1.1	0.3	-0.0	0.4	0.5	0.4	1.7	-0.1	-0.1	0.4	-0.0	1.1
Medication: Cholesterol lowering	0.4	0.6	3.9	0.6	-1.3	0.1	-1.7	0.0	0.0	-0.3	-0.2	-0.6	-0.6	-0.2	0.2	-0.4	-0.3	-2.0	-0.2	-0.8	-0.6
Pulse wave Arterial Stiffness index	0.4	0.4	1.3	-0.1	0.0	0.2	-1.2	0.1	-0.7	0.1	0.4	-0.7	-1.0	-1.1	-0.3	0.7	-0.9	0.9	-0.5	-0.6	-0.3
Arm fat mass (right)	0.4	1.8	6.0	-1.7	-0.1	-1.0	-0.9	-1.0	-1.7	-1.4	-0.6	-1.0	0.1	-1.1	-2.5	-0.2	-1.8	0.6	-2.0	-1.4	-1.6
Glaucoma (self-reported)	0.4	0.4	2.2	0.2	0.4	0.3	1.1	0.2	-0.0	0.4	0.3	0.9	0.8	1.5	0.4	-0.7	0.2	-0.4	0.4	0.2	1.1
Forced vital capacity (FVC), Best measure	0.4	1.6	5.6	-1.6	-1.0	-1.8	-0.7	-0.8	-1.2	-0.9	-0.6	-1.4	-1.7	-2.4	-1.5	-0.1	-1.0	0.5	-1.1	-0.9	-1.4
Number of full brothers	0.4	0.6	2.5	0.3	1.0	1.1	-0.0	1.3	-0.4	0.9	1.2	0.3	-0.8	-0.0	-0.0	0.4	-0.5	1.6	0.2	0.1	0.0
Pulse wave peak to peak time	0.4	0.4	1.0	-0.1	-0.2	-0.5	1.0	-0.4	0.6	-0.4	-0.6	0.6	1.0	1.0	0.1	-0.8	0.9	-0.9	0.4	0.6	0.1
Eye problems/disorders: None of the above	0.4	0.4	1.4	-0.4	0.0	-0.8	0.1	-0.9	-0.0	-0.7	-0.8	0.7	-0.1	0.9	-0.1	-0.7	1.2	-0.8	0.3	1.0	0.0
Whole body fat mass	0.4	1.5	5.2	-1.4	-0.2	-0.8	-1.2	-0.9	-1.4	-1.3	-0.7	-1.0	-0.0	-1.0	-2.3	-0.1	-1.6	0.3	-1.9	-1.4	-1.5
Overall health rating	0.4	0.9	3.1	0.8	-0.7	1.2	-1.8	1.0	-0.0	0.7	0.9	-1.1	-1.6	-0.7	0.3	0.6	-1.1	-0.2	-0.4	-1.1	-0.2
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	2.6	0.0	0.3	0.4	1.1	0.6	-0.3	0.3	0.2	0.8	1.6	0.4	0.5	0.3	0.6	1.3	0.5	0.5	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	2.6	0.5	0.2	-0.4	0.3	-0.6	0.7	-0.5	-0.8	-0.7	1.6	0.7	-0.5	-0.1	-0.3	-1.1	-0.6	-0.5	0.4
Friendships satisfaction	0.4	0.6	2.2	0.4	-0.3	-0.1	-0.1	0.7	1.3	1.0	-0.2	-0.5	-1.2	-1.0	1.1	1.5	0.3	-0.2	0.5	-0.3	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	0.9	0.9	0.8	0.9	0.2	0.6	0.1	0.9	0.7	1.0	0.7	1.0	0.4	0.1	0.3	0.7	0.6	0.6	0.8
Breast cancer (self-reported)	0.4	0.5	1.1	-1.0	-0.1	-0.5	-0.3	-0.8	-0.9	-0.8	-0.9	-0.0	-0.7	-0.4	-0.9	-0.2	-0.5	0.1	-1.0	-0.5	-0.9
Medication: Gliclazide	0.4	0.5	1.5	0.1	0.1	0.9	-1.2	0.2	-1.1	0.3	0.9	-0.6	-0.8	-0.3	-0.5	-0.2	-1.2	0.7	-0.5	-0.7	-0.4
Arm fat mass (left)	0.4	1.6	5.3	-1.5	-0.1	-1.0	-0.9	-1.0	-1.4	-1.3	-0.8	-1.1	0.1	-1.1	-2.3	-0.0	-1.7	0.4	-2.0	-1.4	-1.4
Wears glasses or contact lenses	0.4	0.5	2.0	1.0	0.3	0.8	0.3	1.0	1.4	1.0	0.4	-0.1	0.3	0.3	0.8	0.4	-0.3	-0.4	0.3	-0.3	0.6
Ever taken oral contraceptive pill	0.4	0.5	1.4	-0.3	0.7	-0.4	1.1	0.2	-1.1	0.1	0.8	1.2	0.7	1.2	-0.3	-0.8	0.1	0.5	0.3	0.6	0.0
Medication: Lisinopril	0.4	0.5	1.8	0.6	-0.7	0.8	-0.6	0.3	0.6	0.1	-0.1	-1.2	0.8	0.7	0.0	-0.2	-1.3	-0.9	-0.7	-1.3	0.0
Medication: Atorvastatin	0.4	0.5	2.2	0.7	-0.5	-0.3	-0.5	0.1	1.4	0.2	-0.7	-0.8	-0.9	0.1	0.7	1.5	0.2	-0.9	0.2	-0.4	0.9
Vascular/heart problems diagnosed by doctor	0.4	1.0	3.0	-1.7	1.5	-1.2	1.0	-0.6	-0.6	-0.4	-0.3	1.4	0.5	-0.4	-1.0	-1.0	0.7	1.5	0.0	1.1	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.3	-0.2	-0.7	-0.2	-0.7	-0.2	0.8	-0.5	-0.9	-0.9	0.4	-0.5	-0.5	0.2	-0.5	-1.5	-0.7	-0.9	-0.6
Leg fat mass (left)	0.4	1.4	5.2	-1.5	0.3	-0.9	-0.7	-1.1	-1.8	-1.4	-0.6	-0.4	0.6	-0.6	-2.3	-0.4	-1.5	0.8	-1.8	-1.1	-1.3
Bipolar Disorder or Schizophrenia	0.3	0.8	2.8	-1.1	0.2	-1.7	-0.3	-0.7	-0.5	-1.0	-1.3	0.3	0.2	-1.4	-1.3	-0.3	-0.1	0.2	-0.8	-0.2	-1.3
Worry (Nagel 2018)	0.3	0.5	1.6	-0.7	-0.7	-1.1	-0.4	-0.8	-0.7	-0.7	-0.0	1.3	-0.5	0.7	0.7	-1.1	0.9	0.6	0.4	0.6	0.1
Ulcerative Colitis (UC)	0.3	0.6	1.7	-0.1	-0.8	-0.0	-0.8	0.3	-1.0	0.1	0.7	-0.9	-0.3	-1.3	-1.1	-0.7	-1.3	0.0	-0.7	-0.8	-1.0
Reaction Time	0.3	0.6	3.1	-0.3	-1.8	-0.9	-1.0	-0.6	-0.3	-1.0	-0.7	-0.7	-0.8	-0.9	0.0	-0.3	0.1	-0.6	-0.3	-0.4	-0.8
Breast Cancer	0.3	0.7	2.8	0.0	0.4	-0.2	0.6	-0.8	-1.7	-0.6	0.1	1.4	1.1	1.1	-0.1	-0.5	0.9	0.9	0.4	1.0	0.5
Lupus	0.3	0.4	2.1	0.8	0.5	0.5	-0.1	0.2	1.1	0.3	-0.3	-0.7	-0.8	-0.2	0.1	1.5	-0.3	-0.9	0.0	-0.4	1.0
Rheumatoid Arthritis	0.3	0.4	3.4	-0.4	-0.5	-0.7	1.9	-0.3	0.5	-0.5	-0.4	0.3	0.4	0.4	0.3	-0.8	0.6	-1.2	0.2	0.2	-0.1
Respiratory disease	0.3	0.7	2.6	-0.2	-1.6	0.1	-0.8	0.5	0.3	-0.1	-0.4	-1.3	-0.1	-1.5	-0.3	-0.5	-0.7	-1.4	-0.6	-1.1	-1.2
Neuroticism	0.3	0.6	2.1	-0.5	-0.2	-0.6	-0.5	-0.6	-1.2	-0.2	0.7	1.5	-0.0	0.9	0.8	-1.1	0.7	1.3	0.6	0.9	0.4
Chronotype (morning person)	0.3	0.7	3.1	0.4	0.7	-0.5	1.8	-0.4	-0.4	0.1	0.3	1.6	-0.1	1.0	0.9	-0.5	1.0	1.1	0.8	1.1	0.5
Average weekly fortified wine intake	0.3	0.3	1.4	0.2	0.7	0.3	0.6	0.6	0.9	0.7	0.3	-0.1	0.3	0.1	0.6	1.2	-0.0	0.2	0.4	0.0	1.1
High blood pressure	0.3	0.9	2.4	1.6	-1.4	1.4	-1.0	0.8	0.2	0.5	0.7	-1.4	-0.6	0.5	0.7	0.8	-1.1	-1.1	-0.2	-1.3	0.4
Supplements: Glucosamine	0.3	0.4	1.9	-1.1	-0.4	-0.3	-0.3	-0.3	-0.2	-0.4	-0.6	-0.4	1.1	-0.7	-0.4	-0.7	-0.2	-1.4	-0.4	-0.3	-0.7
Body mass index (BMI)	0.3	1.4	4.7	-1.3	0.2	-1.0	-0.3	-1.2	-1.3	-1.4	-0.9	-0.8	0.9	-0.5	-2.2	-0.4	-1.6	0.3	-1.9	-1.2	-1.3
Trunk fat mass	0.3	1.1	3.7	-1.1	-0.2	-0.6	-1.3	-0.7	-1.2	-1.0	-0.5	-1.0	-0.2	-1.0	-1.9	0.3	-1.4	0.2	-1.5	-1.2	-1.3
Waist circumference	0.3	1.0	5.2	-1.1	0.4	-0.1	-0.2	-0.3	-2.3	-0.6	0.4	-0.3	0.9	-0.5	-1.7	-0.4	-1.6	1.0	-1.3	-0.9	-1.1
Hair/balding pattern: Pattern 2	0.3	0.4	1.6	0.6	0.6	0.5	0.3	0.5	0.3	0.8	0.9	0.5	1.1	1.3	0.6	0.6	-0.1	0.6	0.5	0.3	0.6
Forced vital capacity (FVC)	0.3	1.0	3.5	-1.2	0.0	-1.9	0.3	-1.0	-1.2	-0.7	-0.4	-0.5	-1.1	-1.8	-1.5	0.2	-0.2	1.2	-0.6	0.1	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	5.3	-0.4	0.2	-0.4	-1.0	0.2	0.9	0.0	-0.2	-1.3	-0.4	-2.3	-0.3	1.1	0.0	0.7	-0.1	0.0	-0.4
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.6	1.2	0.1	0.4	-0.2	0.6	0.7	0.8	0.1	-0.1	0.4	-0.4	0.7	1.3	-0.2	0.3	0.2	-0.2	0.4
Neuroticism score	0.3	0.7	2.3	-0.9	-1.5	-0.9	-1.5	-0.8	-1.5	-0.9	0.2	0.4	-0.1	-0.1	0.2	-1.2	0.1	0.7	-0.2	0.1	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.4	0.7	-0.2	0.4	-0.5	0.8	0.1	1.1	1.2	-0.7	-0.5	-0.5	0.5	0.9	-1.1	0.2	-0.0	-0.8	0.3
Hair/balding pattern: Pattern 3	0.3	0.4	1.8	0.2	0.2	1.3	-0.3	1.2	-0.2	0.7	1.0	-0.1	-0.2	-1.0	-0.5	-0.3	-0.8	-0.8	-0.1	-0.6	-0.2
Number of live births	0.3	0.4	2.0	1.2	0.1	0.2	0.1	-0.1	1.4	-0.1	-0.8	-0.6	-0.5	-0.9	0.2	1.3	0.5	-0.5	0.1	0.2	0.1
Illnesses of mother	0.3	0.4	1.7	-0.4	0.9	0.3	0.5	0.8	-0.6	0.1	0.3	1.1	0.4	0.8	-0.5	-0.1	0.3	1.3	0.0	0.7	-0.4
Birth weight of first child	0.3	0.6	1.5	-0.9	-0.6	-0.7	-0.6	-1.2	-1.0	-1.2	-0.9	0.3	0.0	-0.3	-0.7	-0.9	0.9	0.2	-0.2	0.7	-1.2
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.9	-0.6	0.2	-0.8	-0.5	-1.1	0.2	-0.7	-0.1	0.5	-1.4	0.9	0.6	-0.3	0.6	0.6	0.2	0.5	0.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.9	-1.2	-0.0	-0.7	-0.7	-0.8	-0.5	-1.2	-1.2	-0.1	-1.4	-1.2	-0.9	0.5	0.4	0.4	-0.6	0.0	-0.6
Exposure to tobacco smoke outside home	0.3	0.3	2.6	0.3	-0.5	0.5	-1.6	0.4	0.0	-0.0	0.2	-0.6	1.0	-0.0	-0.3	0.2	-0.4	-0.9	-0.3	-0.5	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	2.1	-0.1	-0.7	-0.8	0.5	-0.5	0.7	-0.2	-1.2	-0.4	0.1	-1.3	0.1	-0.2	0.3	-1.4	-0.1	-0.3	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.5	-0.8	-1.0	-0.4	0.5	-0.5	-1.2	-0.9	-0.2	0.3	-0.3	-0.2	0.2	-0.5	0.9	0.1	0.2	0.6	-0.5
Hypertension (Self-reported)	0.3	0.9	2.8	1.0	-1.7	1.2	-1.3	0.5	-0.4	0.2	0.6	-1.5	-0.2	0.3	0.2	0.2	-1.4	-1.1	-0.6	-1.5	-0.1
Illnesses of father: Heart disease	0.3	0.4	1.5	-0.2	-1.1	-0.1	-0.2	-0.2	-1.2	-0.2	1.1	-0.4	0.4	-0.1	0.3	-0.8	-0.8	0.8	-0.3	-0.5	-0.6
Illnesses of siblings: Diabetes	0.3	0.3	1.9	0.1	-0.9	0.8	-1.4	0.8	-0.2	0.4	0.8	0.2	0.7	0.5	0.4	0.0	-0.2	-0.3	0.2	-0.4	-0.1
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.8	0.9	-0.5	0.7	0.1	0.3	1.2	0.3	-0.1	-0.2	-0.9	-0.1	1.1	1.4	0.4	-0.2	0.5	-0.0	0.4
Mineral and other dietary supplements	0.3	0.4	1.9	0.4	0.3	0.7	-0.2	0.8	-0.3	0.8	1.1	0.6	0.1	0.3	0.2	0.3	0.0	1.4	0.5	0.5	0.4
Illnesses of father: None of the above (group 1)	0.3	0.3	1.5	0.2	1.2	0.3	0.1	0.6	1.2	0.5	-0.5	-0.0	-0.1	-0.4	-0.4	1.2	-0.1	-0.2	-0.0	-0.1	0.6
Ever had prostate specific antigen (PSA) test	0.3	0.4	2.7	-0.5	-0.3	-0.8	-0.2	-0.2	1.3	-0.2	-0.8	-0.1	-1.6	-0.0	0.4	0.0	0.1	-0.5	-0.2	-0.4	-0.0
Myopia	0.3	0.4	2.0	-0.3	0.7	0.2	0.3	0.6	-0.8	0.6	0.7	1.4	-0.1	0.3	-0.3	-0.4	0.6	1.1	0.6	1.0	0.1
Intelligence (Savage-Jansen 2018)	0.2	0.7	3.3	-0.3	0.2	-0.1	0.2	0.0	-1.8	-0.4	1.2	0.9	1.1	0.4	-0.0	-0.8	1.0	1.1	0.8	1.2	-0.2
Irritable Bowel Disease (IBD)	0.2	0.4	1.5	0.4	0.6	0.5	0.4	1.2	0.2	1.2	1.1	-0.0	0.0	-1.0	-0.0	0.3	-0.7	0.2	0.1	-0.2	-0.1
Ulcerative Colitis	0.2	0.3	1.2	0.4	-0.5	0.2	0.3	0.2	-0.3	0.3	0.6	-0.8	-0.8	-1.1	-0.4	-0.3	-1.0	-0.2	-0.4	-0.6	-0.5
Blood Eosinophil Count	0.2	1.6	4.2	0.1	-0.3	0.9	-1.4	1.2	0.1	0.7	0.5	-1.7	-1.1	-2.0	-0.2	1.2	-2.1	1.8	-1.1	-1.8	-1.2
Hypothyroidism (self reported)	0.2	0.5	3.1	-0.8	-0.2	-0.3	-0.8	-0.6	-0.7	-1.0	-0.7	0.1	-1.7	-1.0	-0.5	0.3	0.8	0.2	-0.2	0.4	-0.5
Sensitivity / hurt feelings	0.2	0.3	1.1	0.2	-0.5	0.8	-0.6	0.7	-0.4	0.6	1.0	0.3	-0.4	-0.6	1.0	0.0	0.4	0.3	0.8	0.4	-0.2
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.6	-0.0	-0.2	-0.1	-1.2	-0.2	-1.3	-0.1	0.7	-0.2	-0.7	0.2	-0.4	-0.1	-0.5	0.8	-0.2	-0.0	-0.2
Ever had hysterectomy (womb removed)	0.2	0.3	1.1	0.6	0.2	1.0	0.4	0.2	1.1	0.1	-0.2	-0.3	-0.2	0.7	0.8	0.6	0.2	-0.4	0.2	0.1	0.5
Medication: Metformin	0.2	0.3	1.0	0.9	0.3	0.8	0.0	0.8	0.6	0.7	0.3	-0.3	0.1	0.4	0.7	1.0	-0.1	-0.5	0.3	-0.3	0.7
Severe depression (siblings)	0.2	0.2	0.9	-0.1	0.9	-0.3	0.9	-0.5	0.3	-0.2	-0.4	0.3	0.4	-0.1	0.1	0.3	0.9	0.3	0.4	0.6	0.6
Pack years adult smoking proportion	0.2	0.3	2.3	0.3	-0.5	0.3	-1.5	-0.3	-0.9	-0.4	-0.1	-0.4	-0.2	0.0	-0.4	-0.4	-0.4	0.1	-0.5	-0.4	-0.1
Townsend deprivation index at recruitment	0.2	0.3	1.0	1.0	0.6	0.6	-0.1	0.0	0.4	0.2	0.2	0.3	0.3	0.5	0.6	1.0	0.8	-0.2	0.7	0.6	0.8
Medication: Levothyroxine sodium	0.2	0.4	2.0	0.0	0.6	0.3	-0.5	0.2	0.3	0.2	0.1	0.2	-1.4	-0.7	0.3	1.2	0.5	0.8	0.3	0.3	0.7
Qualifications: None of the above	0.2	0.5	2.1	0.2	-0.3	0.2	-0.3	-0.2	-0.7	-0.3	0.4	-0.2	1.0	1.4	-0.5	-1.2	-1.5	-0.0	-0.9	-1.1	0.2
Medication: Ramipril	0.2	0.3	3.4	0.6	-0.5	0.2	-0.8	-0.2	-0.0	-0.1	0.0	-0.3	-1.8	0.4	0.6	0.0	0.0	-0.1	0.1	-0.3	0.5
Length of working week for main job	0.2	0.3	1.2	-0.4	-0.1	-0.6	0.6	-0.1	0.3	-0.1	-0.0	0.5	0.3	0.6	0.5	-0.1	1.1	-0.5	0.8	0.9	0.1
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.5	0.2	-0.7	0.4	-1.2	0.5	0.0	0.5	0.8	0.1	-0.1	-0.3	0.3	-0.1	-0.0	-0.4	0.3	-0.2	-0.2
Headache pain in last month	0.2	0.3	2.0	-0.4	0.1	-0.9	0.3	-1.4	0.7	-0.6	-0.8	0.2	-0.1	0.5	0.1	-0.3	0.5	-0.4	0.1	0.4	0.5
Wheeze or whistling in the chest in last year	0.2	0.4	1.1	0.1	-1.0	-0.4	-0.4	-0.3	-0.9	-0.5	-0.4	-0.6	1.0	-0.7	-0.4	-0.2	-0.6	-1.0	-0.7	-0.9	-0.7
Number of children fathered	0.2	0.2	1.0	0.6	0.1	0.8	0.1	0.8	-0.1	0.9	0.4	0.5	1.0	-0.1	0.4	0.3	0.2	0.1	0.4	-0.1	0.1
Qualifications: College or University degree	0.2	0.6	2.3	-1.0	0.4	-0.7	1.1	-0.6	0.1	-0.5	-0.8	0.5	-1.4	-0.3	0.2	0.7	1.5	0.7	0.7	1.3	0.2
Medication: Ibuprofen	0.2	0.3	0.9	0.3	0.4	0.4	-0.3	0.0	-0.8	0.2	0.5	0.5	0.6	0.6	0.7	0.4	0.4	0.9	0.5	0.5	0.8
Pulse rate, automated reading	0.2	0.7	6.2	0.4	0.7	0.7	-0.1	0.8	0.1	0.9	0.6	-0.7	-2.5	-1.1	-0.2	0.8	-0.8	0.8	-0.2	-0.3	-0.1
Suffer from ‘nerves’	0.2	0.3	1.1	-0.1	-0.6	-1.0	-1.0	-0.7	-0.6	-0.4	0.2	0.5	-0.3	0.0	0.7	-0.5	0.7	0.5	0.4	0.5	-0.1
Had major operations	0.2	0.3	1.0	-0.3	-0.3	-0.3	-0.9	-0.3	-0.5	-0.4	-0.4	-0.5	0.5	-0.8	-0.6	-0.3	-0.0	-1.0	-0.2	-0.2	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.0	0.0	-0.0	-0.3	0.5	-0.8	-0.3	-0.4	-0.6	0.6	0.3	0.0	0.5	0.5	1.0	0.5	0.4	0.7	0.2
Mood swings	0.2	0.3	1.4	-0.1	0.1	-0.1	-0.0	-0.2	-0.5	0.1	0.4	0.7	1.2	1.0	0.6	-0.1	0.1	1.0	0.3	0.6	0.6
Loneliness, isolation	0.2	0.3	1.6	0.5	-0.3	0.3	-0.4	0.1	0.2	0.2	0.5	0.4	-0.1	1.3	0.8	-0.2	0.8	-0.5	0.8	0.7	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.2	-0.4	-0.8	-0.8	-0.2	-0.7	-0.8	-0.4	-0.5	-0.6	0.6	-0.4	-0.7	-1.1	-1.1	-0.5	-0.9	-1.0	-0.6
Mother’s age at death	0.2	0.2	1.3	-0.2	-0.5	-0.2	-0.3	-0.5	-1.1	-0.5	0.1	0.3	0.3	0.1	-0.4	-0.9	-0.1	0.4	-0.3	-0.1	-0.5
Risk taking	0.2	0.3	1.3	0.0	-0.5	0.5	-0.6	0.6	0.1	0.0	-0.4	-0.6	-0.3	-1.1	-0.4	1.1	0.2	-0.8	-0.1	-0.1	-0.5
Basal cell carcinoma (self-reported)	0.2	0.2	0.9	0.0	-0.5	0.3	-0.1	0.4	0.1	0.3	-0.2	-0.5	0.5	0.3	-0.3	0.2	-0.7	-1.0	-0.4	-0.9	0.0
Pack years of smoking	0.2	0.3	2.6	0.1	-0.6	0.4	-1.6	-0.2	-0.8	-0.4	-0.1	-0.5	-0.3	0.0	-0.5	-0.6	-0.6	-0.0	-0.6	-0.5	-0.3
Primary Biliary Cirrhosis	0.1	0.2	1.1	-0.2	0.6	-0.5	0.9	-0.2	-0.4	0.1	0.2	0.4	-0.1	-0.3	-0.2	0.4	0.2	1.0	0.2	0.4	0.4
Cardiovascular Disease	0.1	0.4	1.3	0.9	-1.1	0.8	-0.6	0.2	-0.8	0.2	0.7	-0.9	0.3	0.4	0.4	0.1	-0.9	-0.4	-0.3	-0.9	0.0
Type 2 Diabetes (T2D) (2018)	0.1	0.2	1.9	0.1	0.5	0.6	-0.1	0.0	-1.4	-0.2	0.5	0.4	0.7	0.5	-0.4	-0.5	0.1	0.3	0.0	0.2	0.2
Lung FVC	0.1	0.3	1.2	0.7	1.0	-0.3	1.1	0.2	0.1	0.6	0.6	0.2	0.5	0.4	-0.3	0.4	-0.1	0.3	0.4	0.4	0.7
Tanning	0.1	1.2	3.0	1.6	-0.0	0.5	1.7	0.7	1.5	0.3	0.3	0.1	0.4	1.0	1.4	0.5	1.2	-1.7	1.3	1.1	1.6
Trunk fat percentage	0.1	0.3	1.8	0.4	0.6	0.7	-0.7	0.6	-0.2	0.5	0.8	-0.3	-0.7	-0.0	-0.2	1.3	-0.6	0.7	-0.1	-0.3	0.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.4	-0.2	-0.5	0.1	0.3	0.6	-0.7	0.1	0.3	0.3	-0.6	0.5	0.5	0.0	0.3	-0.5	0.4	0.2	0.2
High blood pressure (mother)	0.1	0.2	1.4	0.2	-0.5	-0.6	0.4	-0.7	-0.1	-0.0	-0.1	0.0	0.0	0.3	0.4	-0.4	0.4	-1.2	0.4	0.1	0.5
Nervous feelings	0.1	0.3	1.5	-0.8	-1.2	-0.5	-0.4	-0.2	-0.5	-0.4	0.1	0.4	-0.9	0.0	0.5	-0.6	0.2	0.1	-0.0	-0.0	-0.5
Diabetes (self-reported)	0.1	0.2	0.9	0.3	-0.3	0.5	0.1	-0.1	-0.3	-0.1	-0.3	-0.2	0.8	0.7	0.0	-0.1	-0.0	-0.9	-0.1	-0.4	0.1
Arm fat percentage (right)	0.1	0.3	1.1	0.1	0.6	0.5	-0.4	0.5	-0.5	0.3	0.7	-0.3	0.3	0.3	-0.8	0.6	-1.0	0.4	-0.5	-0.6	0.1
Father’s age at death	0.1	0.2	0.6	-0.6	-0.2	0.4	-0.1	0.7	-0.2	0.8	0.7	0.3	-0.1	-0.2	0.1	-0.8	-0.1	0.5	0.2	-0.1	-0.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	2.2	-0.2	0.7	-0.9	0.9	-0.3	-0.9	0.0	0.4	0.4	-0.4	-0.4	-0.7	0.2	0.2	1.5	0.2	0.7	0.1
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.4	-1.2	0.3	-0.6	-0.1	-0.0	-0.4	-0.2	0.4	0.5	-0.8	-0.0	-0.2	-0.6	0.1	1.2	-0.1	0.1	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.3	-0.8	-0.3	-0.9	0.1	-0.3	-0.7	-0.1	-0.1	-0.5	-1.1	-1.1	-0.6	0.1	-0.5	0.8	-0.4	-0.3	-0.5
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.7	-0.1	0.2	-0.2	-0.8	0.3	0.4	0.5	0.3	0.1	0.3	0.1	0.3	0.6	0.5	-0.3	0.6	0.4	0.2
Body fat percentage	0.1	0.4	1.4	0.5	0.9	0.9	-0.4	0.7	-0.2	0.6	1.0	-0.1	-0.3	0.3	-0.3	1.2	-0.7	0.9	-0.1	-0.3	0.4
Leg fat percentage (right)	0.1	0.3	1.1	0.1	0.7	0.9	0.0	0.6	-0.4	0.4	0.8	0.0	0.6	0.6	-0.4	0.5	-1.0	0.5	-0.4	-0.6	0.4
Alcohol intake frequency.	0.1	0.2	1.0	-0.1	-0.2	-0.0	-0.2	-0.3	-0.3	-0.2	0.3	-0.3	-1.0	0.2	-0.2	-0.3	-0.7	0.6	-0.5	-0.5	-0.1
Arm fat percentage (left)	0.1	0.2	0.9	0.2	0.6	0.4	-0.2	0.4	-0.1	0.3	0.4	-0.4	0.3	0.2	-0.6	0.9	-0.9	0.2	-0.4	-0.6	0.2
Diabetes diagnosed by doctor	0.1	0.2	0.8	0.3	-0.0	0.6	-0.2	-0.1	-0.9	-0.3	-0.2	0.2	0.7	0.7	-0.1	-0.2	0.4	-0.6	0.1	0.1	0.2
Miserableness	0.1	0.2	0.8	-0.2	-0.1	-0.5	-0.9	-0.7	0.2	-0.3	-0.2	0.1	0.3	0.6	-0.1	-0.5	-0.3	0.0	-0.3	-0.1	0.1
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.6	0.2	0.2	-0.4	0.2	0.0	0.5	-0.2	-0.5	-0.5	-0.3	-0.4	0.2	0.4	-0.1	-0.8	-0.2	-0.5	-0.1
Leg fat percentage (left)	0.1	0.5	1.1	0.3	1.0	1.0	-0.1	0.6	-0.5	0.5	1.0	0.2	0.8	0.7	-0.4	0.6	-1.0	1.0	-0.3	-0.5	0.5
Diastolic blood pressure, automated reading	0.1	0.2	1.1	0.6	0.3	-0.3	0.3	-0.1	-0.6	0.1	0.3	0.1	-1.0	0.3	-0.3	0.1	-0.2	0.2	0.1	0.1	0.7
Hair Pigment	0.0	0.9	3.6	-1.1	0.3	-0.3	0.4	-0.2	-1.3	-0.1	0.1	-0.6	-1.6	-0.9	-0.8	0.3	-1.5	1.9	-1.2	-1.1	-0.4

Hub : Genes

CBR1

Models

Trait associations