Best TWAS P=2.24e-17 · Best GWAS P=4.52e-18 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ZNF638 | 0.06 | 0.01 | bslmm | 559 | 0.02 | 1.8e-03 | 8.6 | 5.2 | 1.6e-07 | 0.69 | 0.01 | 0.96 | FALSE |
| 2 | GTEx | Artery Aorta | ZNF638 | 0.25 | 0.07 | enet | 20 | 0.10 | 5.2e-06 | 8.6 | 8.5 | 2.2e-17 | 0.98 | 0.01 | 0.99 | TRUE |
| 3 | GTEx | Artery Tibial | ZNF638 | 0.10 | 0.06 | enet | 13 | 0.07 | 2.4e-06 | 8.6 | 7.7 | 2.0e-14 | 0.88 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | PAIP2B | 0.14 | 0.07 | enet | 39 | 0.07 | 3.0e-06 | 6.1 | 5.2 | 2.0e-07 | 0.66 | 0.32 | 0.64 | FALSE |
| 5 | METSIM | Adipose | PAIP2B | 0.05 | 0.03 | lasso | 9 | 0.03 | 5.0e-05 | 6.1 | 5.7 | 1.6e-08 | 0.75 | 0.64 | 0.29 | FALSE |
| 6 | The Cancer Genome Atlas | Esophageal Carcinoma | ZNF638 | 0.12 | 0.08 | lasso | 1 | 0.07 | 2.2e-03 | 5.6 | 5.6 | 1.8e-08 | 0.76 | 0.05 | 0.66 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | ZNF638 | 0.08 | 0.05 | enet | 10 | 0.05 | 5.6e-06 | 8.6 | 7.9 | 2.0e-15 | 0.88 | 0.01 | 0.99 | FALSE |