Hub : Genes

PAIP2B

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1410	0.0410	2.9e-05	0.062	NA	0.048	NA	0.041	8.1e-06	NA	8.7e-05	NA	2.5e-04
2	GTEx	Artery Aorta	0.0930	0.0390	8.1e-03	0.018	NA	0.006	NA	0.019	3.3e-02	NA	1.4e-01	NA	3.0e-02
3	GTEx	Artery Tibial	0.1019	0.0384	2.2e-03	0.053	NA	0.042	NA	0.053	5.2e-05	NA	3.0e-04	NA	5.5e-05
4	GTEx	Brain Cerebellum	0.3290	0.1140	9.3e-03	0.178	NA	0.085	NA	0.123	6.1e-06	NA	1.7e-03	NA	1.8e-04
5	GTEx	Esophagus Muscularis	0.1560	0.0540	9.2e-04	0.070	NA	0.031	NA	0.034	4.8e-05	NA	5.5e-03	NA	3.5e-03
6	GTEx	Lung	0.1021	0.0365	1.4e-03	0.073	NA	0.051	NA	0.062	2.9e-06	NA	9.0e-05	NA	1.7e-05
7	GTEx	Nerve Tibial	0.1052	0.0378	1.4e-03	0.077	NA	0.067	NA	0.075	3.8e-06	NA	1.7e-05	NA	5.5e-06
8	GTEx	Pancreas	0.1770	0.0680	6.8e-03	0.026	NA	-0.005	NA	0.010	2.7e-02	NA	6.5e-01	NA	1.1e-01
9	GTEx	Skin Not Sun Exposed Suprapubic	0.1460	0.0500	1.3e-03	0.002	NA	-0.002	NA	0.004	2.6e-01	NA	4.2e-01	NA	1.8e-01
10	GTEx	Skin Sun Exposed Lower leg	0.1440	0.0420	1.4e-05	0.073	NA	0.067	NA	0.057	1.2e-06	NA	3.0e-06	NA	1.6e-05
11	GTEx	Spleen	0.3560	0.1210	3.2e-03	-0.007	NA	0.070	NA	0.062	5.4e-01	NA	7.4e-03	NA	1.1e-02
12	GTEx	Stomach	0.1390	0.0530	5.5e-03	0.126	NA	0.029	NA	0.094	1.3e-06	NA	1.5e-02	NA	2.8e-05
13	GTEx	Thyroid	0.1120	0.0400	6.0e-04	0.064	NA	0.025	NA	0.039	1.2e-05	NA	4.6e-03	NA	5.4e-04
14	METSIM	Adipose	0.0519	0.0188	3.7e-04	0.027	0.019	0.025	0.023	0.027	5.5e-05	5.7e-04	1.1e-04	2.0e-04	5.0e-05
15	NTR	Blood	0.0290	0.0100	2.5e-04	0.019	0.004	0.007	0.008	0.011	4.8e-07	2.0e-02	1.6e-03	7.3e-04	1.2e-04
16	ROSMAP	Brain Pre-frontal Cortex	0.0657	0.0231	1.0e-04	0.039	0.040	0.027	0.039	0.034	7.8e-06	5.6e-06	2.0e-04	8.1e-06	3.3e-05
17	TCGA	Breast Invasive Carcinoma	0.0542	0.0216	1.1e-08	0.047	0.045	0.041	NA	0.049	6.4e-10	1.1e-09	8.3e-09	NA	2.2e-10

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	2.8	4.5	9.8	2.3	2.0	2.4	-1.7	2.4	2.4	2.4	2.4	2.4	2.3	0.2	1.6	2.4	1.6	-0.6	3.1	-1.9
Bipolar Disorder or Schizophrenia	3.3	8.1	16.8	3.1	3.5	3.0	-1.2	3.0	3.0	2.9	3.1	2.4	4.1	-0.0	2.6	3.0	3.0	-2.7	3.6	-1.1
Depressed Affect (Nagel 2018)	1.0	2.2	6.9	1.4	-0.4	1.2	1.0	2.3	2.1	2.1	1.1	1.9	1.0	1.0	0.1	2.6	-0.4	1.3	1.6	-0.4
Depression (Nagel 2018)	0.4	0.6	3.3	-0.9	-0.7	-0.0	0.8	0.9	0.6	0.6	-0.2	0.7	0.3	-0.1	-0.8	1.2	-0.0	0.7	0.5	1.8
Intelligence (Savage-Jansen 2018)	2.3	7.0	14.8	-2.1	-2.4	-2.5	0.5	-2.8	-2.7	-2.6	-2.6	-1.0	-3.7	3.3	-2.2	-2.8	-3.8	2.2	-1.7	-3.5
Neuroticism (Nagel 2018)	0.5	1.1	4.3	0.7	-0.8	0.4	0.5	1.6	1.5	1.4	0.5	1.3	0.9	0.5	-0.4	2.1	-0.7	0.9	1.5	0.0
Schizophrenia (2018)	2.0	4.2	11.2	2.2	2.9	1.9	-0.2	2.0	1.8	1.8	2.1	1.2	3.4	-0.2	2.0	1.9	2.6	-2.9	2.0	0.1
Schizophrenia vs Biploar Disorder	1.7	2.3	7.7	-1.2	-0.4	-1.8	-0.1	-1.7	-1.7	-1.6	-1.6	-1.6	-0.1	-2.2	-1.5	-1.3	-0.5	-0.2	-1.9	2.8
Worry (Nagel 2018)	0.2	0.5	1.8	0.6	0.2	0.3	-0.1	1.0	0.9	0.9	0.4	0.8	0.8	-1.0	-0.2	1.4	-0.1	0.0	0.3	0.2
Alzheimer’s Disease (in mother)	1.8	2.1	9.1	1.3	1.1	1.0	-0.2	1.3	1.0	1.0	1.1	2.1	3.0	0.8	0.8	1.1	1.1	-2.6	1.1	-1.4
Alzheimer’s Disease (in father)	0.6	0.6	1.7	0.9	0.4	0.9	-0.5	0.5	0.7	0.7	1.1	0.9	0.9	-0.3	0.7	0.4	0.6	0.1	1.3	-1.3
Alzheimer’s Disease (including proxy)	2.4	3.5	10.4	2.1	1.3	1.9	-0.2	1.8	1.7	1.7	2.2	1.7	3.2	0.6	1.8	1.5	1.4	-2.6	2.8	-0.8
Crohns Disease (2017)	0.7	1.5	2.2	1.4	1.2	1.3	1.5	1.5	1.4	1.3	1.5	1.4	1.5	0.7	1.2	1.2	0.3	-1.1	0.7	-0.6
Irritable Bowel Disease (IBD)	1.0	2.3	4.8	1.4	1.6	1.6	0.6	2.1	2.1	2.0	1.7	2.2	2.0	0.0	1.5	2.2	0.7	-0.5	0.6	-0.2
Ulcerative Colitis (UC)	1.1	2.1	5.4	0.9	1.4	1.6	-0.5	2.1	2.1	2.0	1.6	1.9	1.5	-0.4	1.3	2.3	0.9	0.2	0.3	0.2
Major Depression (MDD)	0.7	0.9	2.5	0.7	-0.1	1.1	0.0	1.3	1.2	1.3	1.3	-0.6	0.3	0.4	1.6	1.0	0.3	0.6	1.2	0.8
Reaction Time	4.4	8.4	22.4	2.6	3.3	2.8	-2.0	2.4	2.7	2.7	2.8	2.6	3.6	1.2	3.2	2.4	4.2	-4.7	2.5	-1.1
Verbal and Numeric Reasoning (VNR)	0.8	1.9	17.2	0.0	-0.2	-0.7	0.6	-0.8	-0.9	-0.7	-0.9	0.9	-1.5	2.3	-0.3	-0.8	-1.7	0.2	-0.3	-4.2
Breast Cancer	0.9	2.3	8.2	-1.9	-1.6	-1.3	-0.2	-1.6	-1.6	-1.7	-1.5	-0.8	-1.2	-2.9	-1.9	-1.7	-1.0	1.2	-1.2	-0.0
Ovarian Cancer	0.2	0.3	2.7	0.6	0.4	0.3	0.5	0.2	0.3	0.3	0.2	0.7	0.0	-0.8	0.2	0.2	-0.1	-0.1	-0.3	1.7
Prostate Cancer	0.8	1.1	2.1	0.9	1.4	1.4	0.6	1.4	1.4	1.4	1.5	1.3	0.5	0.6	0.9	1.4	0.7	-0.0	0.2	-0.5
Age at First Birth	1.0	1.4	3.8	-1.3	-0.5	-1.3	-0.9	-1.2	-1.3	-1.4	-1.4	-0.5	-0.7	-1.9	-1.7	-1.2	-1.5	-0.9	-0.6	0.6
Bipolar Disorder (2011)	3.6	3.5	7.6	1.2	1.7	2.4	0.0	1.8	2.0	2.1	2.8	1.8	1.8	0.4	2.7	1.7	2.2	-0.4	2.3	-1.6
Body Mass Index (BMI) (2010)	0.1	0.2	1.1	-0.1	-0.1	-0.1	0.1	0.2	0.2	0.1	-0.4	1.1	-0.1	0.6	-0.6	0.5	0.2	-0.3	-0.4	0.1
Coronary Artery Disease (CAD)	0.3	0.4	2.2	-0.1	0.1	0.0	0.2	-0.4	0.0	0.0	-1.0	0.5	-0.5	0.9	0.1	-0.1	-0.9	-1.5	0.2	-0.9
Crohns Disease (2012)	0.7	1.1	2.4	0.5	0.8	1.4	1.4	1.4	1.3	1.3	1.6	0.7	1.1	-0.0	1.5	1.0	0.1	-0.0	1.0	-0.3
Mean Putamen Volume	1.2	1.4	4.1	-1.6	-0.2	-1.2	-0.6	-1.2	-1.0	-1.1	-1.0	0.4	-1.2	-0.2	-1.7	-0.7	-1.4	1.9	-2.0	0.5
Fasting Glucose	2.3	2.8	5.2	1.6	1.6	2.3	-2.0	2.1	2.0	1.9	1.8	1.4	2.2	-0.6	2.0	1.7	1.4	-0.5	1.2	-0.0
HbA1C	0.5	0.5	2.3	-1.0	-1.5	-0.4	-0.3	-0.7	-0.5	-0.6	-0.4	-1.0	-0.8	0.6	-0.0	-0.8	-1.3	-0.2	0.3	0.3
HDL Cholesterol	0.6	0.9	2.8	-0.8	-0.3	-0.9	-1.4	-1.1	-1.1	-1.2	-0.2	-0.5	0.8	-1.1	-1.3	-1.0	0.5	0.2	-1.7	0.7
LDL Cholesterol	0.9	1.4	7.1	-0.1	-1.6	-0.1	1.3	0.2	0.2	0.0	-0.5	0.9	-2.3	0.7	-1.0	0.0	-2.7	1.6	-0.9	-1.1
Lupus	0.4	0.6	1.5	0.5	0.7	1.0	0.2	0.9	1.0	1.1	0.8	0.8	1.2	-0.5	0.9	1.0	0.5	0.5	0.7	-0.2
Neuroticism (2016)	0.6	0.8	2.5	-0.2	-0.9	0.3	-0.3	1.0	1.1	1.1	-0.0	-0.2	-0.7	-0.9	0.5	1.3	-1.1	1.6	1.1	1.2
Primary Biliary Cirrhosis	0.6	0.8	4.3	0.5	0.1	0.9	-0.7	0.3	0.4	0.4	0.9	-1.4	0.5	-0.7	0.8	-0.0	1.5	0.8	0.7	2.1
Rheumatoid Arthritis	1.6	2.2	5.0	-1.1	-1.6	-1.8	-1.9	-1.4	-1.4	-1.6	-1.7	-0.2	0.1	-1.3	-2.2	-1.1	-1.7	1.4	-1.6	-0.8
Schizophrenia (2014)	1.4	3.0	7.7	1.9	2.3	1.6	-0.5	1.9	1.7	1.7	1.7	0.7	2.8	-1.0	1.4	1.9	1.7	-1.8	2.2	1.0
Triglycerides	0.6	1.0	2.8	-1.0	-1.1	-0.9	1.1	-0.4	-0.4	-0.5	-1.6	1.1	-1.7	0.1	-1.1	-0.3	-1.7	-0.3	-0.4	-0.8
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.7	0.5	0.4	1.3	0.6	1.1	1.1	0.9	0.9	1.3	0.3	-0.5	0.3	0.9	0.3	-0.6	-0.1	-0.2
Ulcerative Colitis	1.2	1.7	5.0	0.4	1.4	1.4	0.0	1.8	1.9	1.7	1.4	2.0	1.5	-0.3	0.8	2.2	0.5	0.3	0.0	0.1
Blood Eosinophil Count	0.9	6.8	27.7	2.2	1.2	2.3	-1.7	2.6	2.3	2.5	2.0	2.5	0.8	5.3	2.7	2.1	0.5	-0.0	3.6	-4.4
Blood Platelet Count	0.1	1.2	6.2	1.3	1.4	0.6	1.1	1.1	1.0	0.9	0.4	-0.2	0.8	0.3	0.5	1.3	0.3	1.8	0.5	2.5
Blood Red Count	0.1	1.1	2.7	-0.9	0.4	-1.4	-1.2	-1.4	-1.4	-1.3	-1.2	0.3	0.2	-0.0	-1.0	-1.0	0.1	0.1	-1.6	-1.6
Blood White Count	0.3	2.6	18.8	-0.1	-1.6	-0.4	-1.0	-0.3	-0.3	-0.2	-0.3	-0.3	-2.6	4.3	0.2	-0.5	-1.7	3.0	0.2	-1.2
Heel T-Score	2.6	20.5	38.2	-4.9	-5.6	-4.8	-1.9	-5.4	-5.2	-5.2	-5.0	-3.9	-5.3	-2.3	-4.1	-5.5	-6.2	2.5	-4.0	-1.6
BMI	0.8	4.6	11.6	-3.4	-2.0	-2.7	-1.6	-2.5	-2.6	-2.5	-2.6	-1.1	-1.6	-0.3	-2.2	-2.3	-2.3	-1.8	-1.7	-0.8
Height	3.5	68.3	182.2	8.9	9.5	8.9	-0.6	8.5	8.3	8.1	9.0	5.1	12.1	-0.1	7.0	8.1	13.5	-8.0	9.3	2.0
Waist Hip Ratio (WHR)	1.1	5.0	8.2	-2.5	-2.4	-2.6	0.2	-2.7	-2.7	-2.6	-2.4	-1.4	-1.3	-1.4	-1.8	-2.8	-2.9	-1.9	-2.7	-1.5
Systolic Blood Pressure	0.5	2.7	20.1	0.8	1.9	-0.2	-0.9	0.8	0.5	0.6	-0.1	2.4	2.7	-1.7	-0.5	1.3	1.4	-4.5	-0.2	-0.8
Smoking Status	0.4	1.0	5.2	1.2	0.5	1.0	0.2	1.0	0.8	0.9	1.1	-0.6	-0.3	2.3	1.1	0.5	0.7	-0.7	1.6	-0.8
Allergy or Eczema	1.3	3.4	6.2	-1.9	-1.9	-2.2	-1.7	-2.2	-2.2	-2.1	-2.5	-0.5	-1.6	-0.8	-2.1	-2.0	-2.1	1.6	-1.6	-1.2
Cardiovascular Disease	0.2	0.6	6.6	-0.3	-0.4	-0.3	-0.5	-0.1	-0.2	-0.2	-0.2	0.5	1.0	-0.1	-1.0	0.0	-0.2	-2.6	0.1	0.1
Hypothyroidism (self reported)	0.5	1.2	3.2	-1.3	0.6	-1.4	-1.4	-1.0	-1.2	-1.3	-1.4	-1.0	1.1	-1.4	-1.8	-0.7	-0.2	-0.4	-0.8	0.6
Respiratory disease	1.0	2.2	4.4	0.3	1.9	1.6	-0.0	1.5	1.8	1.9	1.7	1.7	1.6	1.0	2.1	1.7	1.4	0.0	1.0	-1.5
Type 2 Diabetes (T2D) (2018)	0.3	0.6	3.5	0.4	0.0	-0.6	-0.2	-0.6	-0.7	-0.6	-0.4	-1.6	0.2	-0.1	0.0	-0.8	0.7	-1.9	0.2	-0.5
Lung FEV1/FVC ratio	0.3	1.7	9.1	-1.1	-3.0	-0.7	0.8	-0.6	-0.6	-0.8	-0.6	-0.0	-1.5	1.9	-1.6	-0.7	-2.3	1.1	-0.1	0.7
Lung FVC	0.1	0.7	4.5	-0.3	0.7	-0.5	-1.6	-0.4	-0.2	-0.2	-0.3	0.4	0.7	-2.1	-0.8	0.2	0.2	-0.6	-1.3	0.5
Neuroticism	0.4	1.0	4.3	0.5	-0.4	0.6	1.0	1.6	1.6	1.5	0.7	1.4	0.6	0.2	-0.1	2.1	-0.7	0.3	0.8	0.2
Chronotype (morning person)	0.5	1.2	8.4	0.9	-0.4	0.2	0.4	0.3	0.1	0.3	0.1	-2.4	-0.4	-0.6	1.3	-0.0	-0.3	-1.4	0.6	2.9
Hair Pigment	0.0	0.9	4.5	0.8	1.3	0.8	-0.5	0.5	0.6	0.6	0.6	0.5	1.5	0.3	0.6	0.6	1.2	-2.1	0.5	-0.8
Tanning	0.0	0.5	2.5	-0.4	-1.0	0.1	-0.7	-0.5	0.3	-0.3	0.2	-1.0	-1.4	-0.8	0.3	-0.1	-0.6	1.6	-0.2	0.4
Hand grip strength (left)	1.8	4.7	12.0	1.7	2.4	2.0	0.5	2.8	2.4	2.4	1.7	2.1	2.5	1.0	1.6	2.8	2.1	-3.5	2.6	0.3
Number of treatments/medications taken	0.5	0.8	3.9	0.7	1.4	-0.0	-0.2	0.6	0.4	0.4	-0.1	1.2	1.8	1.1	0.1	0.8	-0.0	-2.0	0.2	-0.9
Average weekly spirits intake	0.9	1.1	8.7	0.1	0.8	-0.0	-0.1	0.0	-0.0	-0.1	-0.3	0.1	1.5	1.8	-0.0	0.1	0.7	-3.0	-0.5	-1.5
Sensitivity / hurt feelings	0.6	1.0	2.5	1.3	-0.5	1.0	-0.5	1.4	1.4	1.3	0.9	0.1	-0.7	1.1	0.5	1.3	-0.5	0.0	1.6	0.6
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.5	-0.0	0.2	0.8	1.3	1.2	1.1	1.2	0.4	0.2	0.4	0.8	0.6	1.4	0.8	0.4	1.1	1.6
Hearing difficulty/problems: Yes	3.9	6.0	11.6	1.9	3.4	2.6	-0.3	2.7	2.9	2.8	2.8	3.0	2.6	1.3	2.8	2.9	3.0	0.3	0.7	-2.1
Relative age of first facial hair	0.6	1.3	4.0	0.4	1.6	0.5	-1.3	0.9	0.7	0.8	0.5	1.4	1.1	1.4	0.7	1.1	2.0	1.0	0.6	-1.6
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	2.8	-0.3	1.7	-0.1	0.2	0.3	0.5	0.6	0.0	-0.2	1.3	-0.1	0.9	0.9	0.6	0.6	-0.8	0.6
Ever used hormone-replacement therapy (HRT)	1.0	1.2	3.8	-2.0	-0.7	-1.4	0.6	-1.2	-1.1	-1.0	-1.3	-0.6	-1.2	0.4	-0.3	-0.9	-1.1	0.2	-1.2	-1.7
Ever had hysterectomy (womb removed)	0.5	0.6	3.2	-1.8	-0.2	-0.9	-1.4	0.4	-0.1	0.1	-1.0	1.4	-0.3	0.1	-0.7	0.7	-0.3	0.5	-0.2	-0.1
Systolic blood pressure, automated reading	0.3	1.0	4.0	-0.5	1.0	-0.8	-1.3	0.1	-0.2	-0.1	-0.7	1.5	1.5	-1.7	-0.7	0.4	0.6	-2.0	0.0	-0.4
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	2.9	0.7	-0.5	0.3	-0.6	0.4	0.4	0.2	0.2	-0.8	0.8	-1.7	-0.3	0.2	-0.4	-1.7	1.1	0.4
Angina	0.6	0.8	5.9	-1.4	-0.1	-0.7	2.4	-0.9	-0.9	-0.9	-0.7	-0.2	0.5	0.3	-1.0	-1.0	-0.0	-0.7	0.0	0.2
Medication for hormone replacement therapy	0.5	0.6	4.2	0.1	-0.4	0.2	-1.4	0.5	0.4	0.5	0.4	1.2	-0.4	0.4	0.4	0.6	-0.6	-0.3	-0.2	-2.1
Vitamin and mineral supplements	1.6	2.1	5.0	-1.6	-2.2	-1.3	-0.7	-1.7	-1.7	-1.7	-1.1	-2.1	-1.8	-0.0	-0.8	-2.1	-1.8	-1.0	-0.2	0.1
Supplements: Zinc	6.2	6.7	17.5	1.7	2.9	2.7	0.4	3.6	3.6	3.5	2.4	4.0	2.7	1.3	1.5	4.2	1.6	0.9	1.9	0.5
Medication: Co-codamol	0.4	0.4	2.0	-0.4	1.4	0.2	0.4	-0.4	-0.0	0.1	0.0	-0.8	0.1	0.4	0.9	0.0	1.2	-0.5	0.1	1.3
Medication: Metformin	0.4	0.5	2.4	0.9	0.7	0.6	-0.5	0.5	0.4	0.4	0.5	-0.3	1.0	-0.1	0.8	0.2	1.3	-1.5	0.5	0.4
Diabetes (father)	2.7	3.4	8.2	0.8	2.7	1.7	1.7	2.3	2.3	2.4	1.4	2.5	1.7	1.1	2.1	2.9	1.3	-0.0	0.8	-0.2
Diabetes (mother)	1.0	1.3	2.6	0.3	1.6	1.5	-0.3	1.0	1.3	1.3	1.6	1.1	1.0	-0.2	1.3	1.3	1.0	-1.6	1.2	0.5
Severe depression (siblings)	1.9	2.1	4.0	-1.7	-1.1	-1.4	0.7	-1.8	-1.8	-1.8	-1.4	-1.5	-1.9	-0.1	-0.9	-2.0	-1.2	1.6	-1.7	0.1
Pack years adult smoking proportion	1.8	2.8	5.2	1.7	1.8	1.8	0.1	1.6	1.7	1.6	1.6	2.3	1.4	2.2	1.1	1.7	1.4	-2.0	1.6	-1.4
Impedance of leg (right)	0.2	0.8	3.6	0.0	-1.9	-0.8	-0.1	-0.6	-0.7	-0.7	-0.8	-1.3	-0.7	-1.0	-1.0	-0.6	-1.1	0.6	0.3	1.1
Leg fat-free mass (left)	1.6	8.6	18.3	2.4	3.6	2.8	-1.0	3.2	3.0	3.1	3.0	2.4	4.3	0.7	2.8	3.2	3.9	-3.9	2.5	-1.1
Trunk fat percentage	0.4	1.7	7.1	-1.2	-0.0	-1.4	-2.3	-1.1	-1.2	-1.1	-1.4	0.4	0.6	-0.0	-0.9	-0.8	-0.8	-2.0	-0.7	-2.7
Hand grip strength (right)	1.8	4.9	14.1	1.3	2.4	1.9	-0.3	2.7	2.3	2.3	1.6	2.7	3.1	1.0	1.4	2.8	2.0	-3.8	2.1	-0.9
Townsend deprivation index at recruitment	1.5	2.1	7.2	-2.5	-2.1	-1.4	1.3	-1.2	-1.1	-1.1	-1.3	-0.3	-2.7	1.6	-1.0	-1.0	-1.7	0.5	-1.0	0.8
Current tobacco smoking	0.1	0.2	2.3	-0.2	-0.1	-0.4	0.4	-0.2	-0.4	-0.4	-0.3	-0.2	-0.4	1.5	-0.5	-0.2	0.5	0.4	0.4	0.1
Average weekly fortified wine intake	1.1	1.2	5.7	1.0	0.3	1.4	-0.4	0.7	0.9	0.7	1.2	-0.8	-0.8	0.7	0.6	0.4	0.2	2.4	1.7	1.8
Maternal smoking around birth	1.0	1.5	4.1	1.1	1.5	0.7	-0.9	1.3	1.1	1.1	0.8	2.0	1.8	0.4	0.3	1.5	1.6	-1.1	0.9	-1.0
Fed-up feelings	0.9	1.6	4.5	1.3	0.0	0.9	1.4	1.7	1.6	1.6	0.8	1.2	1.4	1.1	0.0	2.1	-0.1	1.3	1.1	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.2	-0.1	-0.7	-0.2	0.6	0.7	0.4	0.4	-0.4	0.7	0.5	0.5	-1.0	1.0	-0.4	0.2	-0.2	1.1
Relative age voice broke	0.3	0.4	1.2	-0.6	0.6	-0.6	-0.8	-0.3	-0.5	-0.3	-0.7	-0.8	-1.1	0.4	0.7	-0.4	-0.3	-0.7	-0.6	-1.0
Taking other prescription medications	0.7	1.0	3.7	-1.2	0.5	-1.4	0.8	-1.0	-1.1	-1.0	-1.3	-0.6	1.0	-1.1	-1.1	-0.5	-0.1	-0.4	-1.9	0.3
Age when periods started (menarche)	3.5	8.3	17.1	3.1	3.2	3.5	-0.5	3.3	3.2	3.3	3.7	1.3	2.4	2.2	3.8	2.8	4.1	-0.5	3.3	0.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	2.5	-0.9	-0.7	-0.5	-1.6	-0.6	-0.4	-0.3	-0.4	-0.3	-0.6	0.5	0.0	-0.3	-0.7	-0.3	0.5	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	2.1	4.7	8.7	-2.6	-2.2	-2.3	-0.3	-2.6	-2.5	-2.5	-2.2	-2.1	-2.9	-1.3	-1.4	-2.8	-3.0	0.7	-2.2	-0.8
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	1.9	-0.8	-0.4	-0.2	-0.6	-1.1	-0.9	-0.8	-0.2	-1.1	-0.7	-1.0	0.3	-1.4	-0.3	-0.3	-0.6	-0.8
Qualifications: CSEs or equivalent	3.2	4.3	9.5	2.9	1.5	2.8	1.9	2.3	2.5	2.4	3.1	-0.0	1.4	-0.8	2.4	2.1	2.1	-1.0	1.9	1.8
Serious illness, injury or assault to yourself	0.6	0.7	2.4	-1.1	-0.6	-0.5	-1.6	-1.3	-0.8	-0.8	-0.4	-0.8	-0.8	-0.6	-0.3	-1.0	-0.5	0.8	-0.4	0.8
High blood pressure	0.9	2.5	17.4	0.8	1.7	0.5	-1.3	0.7	0.7	0.7	0.6	2.0	2.6	-0.9	0.4	1.0	1.4	-4.2	0.2	-1.9
Hayfever, allergic rhinitis or eczema	1.5	3.2	5.6	-1.6	-2.1	-1.8	-1.8	-1.8	-1.8	-1.8	-2.2	-0.4	-2.0	0.0	-2.0	-1.7	-2.4	1.7	-1.7	-1.6
Multivitamins +/- minerals	0.9	1.1	3.4	0.3	1.5	0.6	1.1	1.0	0.8	0.8	0.4	1.8	1.4	0.5	0.2	1.2	1.3	1.7	-0.1	-1.1
Stomach or abdominal pain in last month	0.4	0.6	2.7	-1.3	-0.6	-0.3	1.6	-0.1	-0.4	-0.3	-0.5	-0.1	-1.1	0.7	-0.0	-0.6	-1.0	0.9	-0.3	0.6
Supplements: Glucosamine	0.8	1.0	2.9	1.3	1.7	0.7	0.4	1.2	1.1	1.1	0.5	0.6	1.4	-0.8	1.0	1.4	1.2	-0.3	0.1	-0.7
Diverticular disease/diverticulitis (self-reported)	1.9	2.2	6.6	-2.6	-1.5	-2.2	-0.7	-1.7	-1.6	-1.5	-2.2	-0.1	-0.6	-0.6	-1.4	-1.2	-2.2	-0.3	-1.4	0.0
Medication: Atenolol	0.8	1.0	4.8	-0.2	0.7	-0.6	0.4	-0.2	-0.4	-0.4	-0.5	1.2	1.8	1.2	-0.8	-0.1	-0.0	-1.7	-0.8	-2.2
Medication: Levothyroxine sodium	0.4	0.6	2.4	-0.1	0.8	-0.6	-0.8	-0.4	-0.4	-0.5	-0.6	-0.4	1.5	-1.5	-0.8	-0.1	0.4	-0.9	-1.2	0.2
Sitting height	3.2	22.7	58.2	5.6	5.5	4.6	-0.1	5.1	4.7	4.7	4.7	3.5	7.3	1.0	4.4	4.9	7.6	-5.2	4.2	0.2
Chronic bronchitis/emphysema (father)	1.6	1.9	8.0	-0.8	-0.2	-0.9	-2.8	-1.0	-1.1	-1.1	-0.6	1.0	0.2	-0.9	-0.5	-1.2	0.1	-2.7	-1.3	-2.7
High blood pressure (mother)	0.7	1.0	3.9	-0.3	-1.2	-0.6	-0.9	-0.8	-1.0	-1.1	-0.7	-0.3	0.9	-1.4	-1.5	-1.3	-0.6	-2.0	-0.0	-0.4
Body mass index (BMI)	0.5	2.1	5.0	-2.1	-0.3	-1.8	-1.5	-1.4	-1.6	-1.4	-1.7	-0.4	-0.9	0.2	-0.8	-1.3	-1.8	-1.7	-1.4	-2.2
Impedance of leg (left)	0.1	0.3	1.2	0.5	-1.1	-0.2	0.2	-0.2	-0.2	-0.2	-0.3	-0.6	-0.3	-0.5	-0.3	-0.2	-0.4	0.6	0.8	1.0
Leg predicted mass (left)	1.6	8.6	17.7	2.4	3.7	2.8	-0.9	3.2	3.0	3.1	2.9	2.4	4.2	0.7	2.9	3.2	3.9	-3.9	2.4	-1.2
Trunk fat mass	0.4	1.5	9.9	-0.3	1.2	-0.5	-2.1	-0.1	-0.3	-0.1	-0.4	0.9	1.8	0.2	0.1	0.2	0.7	-3.1	0.2	-2.3
Waist circumference	0.5	1.8	11.8	-1.3	0.3	-1.3	-1.8	-1.0	-1.3	-1.1	-1.1	-0.4	0.9	-0.3	-0.2	-1.0	-0.2	-3.4	-0.7	-2.1
Number of incorrect matches in round	0.7	1.1	3.1	-1.2	-0.4	-1.3	-1.0	-1.3	-1.4	-1.4	-1.3	-1.8	-0.7	0.8	-0.5	-1.5	-0.2	-0.3	-0.1	0.9
Past tobacco smoking	1.3	2.3	7.5	-1.9	-0.3	-1.8	1.5	-1.6	-1.6	-1.6	-1.8	0.2	0.6	-2.7	-1.9	-1.1	-0.1	0.9	-2.2	0.9
Alcohol usually taken with meals	0.8	1.3	10.4	-0.9	0.1	-0.9	-3.2	-0.9	-0.9	-0.8	-1.1	-0.8	0.6	-1.8	-0.8	-0.6	0.6	-0.0	-1.1	0.2
Nervous feelings	0.2	0.4	1.6	-0.8	-0.8	-0.3	0.2	-0.0	-0.1	-0.1	-0.4	-0.6	-0.5	-1.2	-0.6	-0.0	-0.9	0.4	-0.5	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	3.8	-2.0	-0.7	-1.1	0.2	-0.7	-0.7	-0.6	-1.0	-0.9	0.1	-0.7	-0.8	-0.3	-1.1	0.1	-0.4	0.4
Hearing difficulty/problems with background noise	2.6	4.2	7.3	1.5	2.4	2.4	-0.8	2.7	2.6	2.6	2.5	2.5	1.4	0.9	2.2	2.5	2.1	0.9	1.5	-0.8
Hair/balding pattern: Pattern 2	0.6	0.7	2.5	-0.3	-1.2	0.8	1.6	0.2	0.5	0.3	0.9	-1.1	-0.4	0.3	0.1	-0.1	-0.6	1.3	1.2	1.3
Had menopause	3.0	3.8	8.1	-2.3	-1.6	-2.4	-0.4	-1.8	-2.1	-2.1	-2.3	-1.7	-1.6	-2.8	-2.1	-1.7	-1.8	1.2	-2.4	1.5
Had other major operations	0.7	0.8	2.5	-0.3	1.3	-1.0	-0.6	-0.3	-0.3	-0.2	-0.9	1.1	1.6	-1.0	-0.5	0.4	-0.1	-1.4	-1.0	-1.5
Forced vital capacity (FVC)	1.3	5.2	13.1	2.5	2.2	2.4	0.1	2.7	2.6	2.4	2.5	2.0	3.6	-0.5	1.2	2.7	3.0	-2.5	1.8	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	1.8	4.0	7.1	-2.5	-1.9	-2.2	-0.2	-2.7	-2.5	-2.4	-2.1	-1.9	-2.6	-1.0	-1.2	-2.6	-2.1	1.1	-2.1	-0.6
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	3.4	-1.8	-0.3	-0.8	-0.5	-0.6	-0.6	-0.7	-0.8	1.4	0.4	1.1	-1.6	-0.2	0.0	0.1	-1.6	-0.2
Qualifications: None of the above	0.2	0.5	1.7	0.4	-0.1	0.4	0.6	0.5	0.5	0.6	0.4	0.2	0.6	0.9	0.9	0.4	0.9	-1.1	1.3	1.1
Financial difficulties in last 2 years	0.3	0.4	1.5	0.0	-0.5	0.3	1.2	0.2	0.2	0.1	0.2	0.1	-0.9	0.9	0.1	0.1	-0.5	1.2	0.6	1.0
Mouth/teeth dental problems	0.4	0.5	2.4	0.7	-1.6	0.3	-0.9	0.3	0.4	0.2	0.3	1.0	1.3	-0.6	-1.3	0.4	0.2	0.1	0.2	0.0
Heart attack	1.9	2.4	11.8	-1.5	-0.0	-1.6	3.4	-2.1	-1.9	-1.9	-1.4	0.2	0.1	0.0	-1.6	-1.8	-0.5	-1.3	-1.6	-0.3
Allergy	0.4	0.9	4.3	1.3	1.2	0.3	1.0	0.4	0.3	0.3	0.4	-0.5	0.9	0.3	0.6	0.4	1.5	-1.1	0.7	2.1
Pain all over the body in last month	1.1	1.2	2.8	1.3	1.1	1.3	0.5	0.8	1.1	1.1	1.4	1.7	0.5	1.3	1.5	0.9	0.9	-0.3	0.8	-0.6
Diabetes (self-reported)	0.2	0.3	1.8	-0.1	0.2	-0.2	0.6	-0.4	-0.3	-0.3	-0.1	-0.6	0.4	-0.4	-0.2	-0.4	0.8	-1.3	0.4	0.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.0	0.0	-1.4	-0.6	-0.3	-0.5	-0.5	-0.4	-0.8	-1.0	-1.2	1.1	-0.3	-0.6	-0.5	1.0	0.2	-0.2
Medication: Ramipril	0.7	0.9	6.9	0.3	1.1	0.3	0.1	-0.1	0.2	0.2	0.1	1.6	1.9	-0.1	0.2	0.3	1.1	-2.6	-0.3	-0.2
Medication: Simvastatin	0.2	0.4	1.2	0.6	-1.1	0.2	-1.0	-0.4	-0.4	-0.5	0.3	-0.8	-0.0	-0.6	-0.3	-0.9	-0.2	0.4	0.2	0.8
Fluid intelligence score	1.4	2.9	8.9	-0.8	-1.7	-1.4	0.6	-1.6	-1.7	-1.6	-1.8	-0.9	-2.5	1.7	-0.8	-1.9	-2.9	0.5	-0.8	-3.0
Illnesses of siblings	0.5	0.6	2.8	0.8	0.0	0.6	0.4	1.0	0.9	0.8	0.6	-0.0	1.0	-1.0	-0.4	1.2	-0.2	0.3	0.7	1.7
Neuroticism score	0.5	1.0	3.4	1.0	-0.4	0.9	0.7	1.6	1.6	1.5	0.9	0.7	0.6	0.1	0.0	1.9	-0.5	0.1	1.2	0.8
Weight	0.8	3.8	16.5	0.9	2.8	1.1	-1.3	1.6	1.3	1.5	1.2	1.1	3.1	0.6	1.8	1.6	2.7	-4.1	1.5	-1.6
Impedance of arm (right)	0.1	0.3	1.5	-0.0	-1.1	-0.2	-0.3	-0.5	-0.3	-0.5	-0.3	0.2	0.3	-0.6	-1.2	-0.3	-0.3	0.8	-0.7	0.5
Arm fat percentage (right)	0.9	3.7	6.2	-2.5	-1.2	-2.5	-1.7	-2.4	-2.3	-2.2	-2.4	-0.6	-1.1	0.2	-1.8	-2.0	-2.3	-1.5	-2.0	-2.3
Trunk fat-free mass	2.3	13.1	31.9	3.1	4.7	3.3	-0.4	4.0	3.6	3.8	3.4	2.3	5.2	0.8	3.6	3.9	5.7	-4.7	3.3	-0.1
Hip circumference	0.8	3.4	8.9	1.0	2.7	1.2	-1.2	1.5	1.3	1.6	1.4	0.7	2.7	1.1	2.3	1.5	2.3	-3.0	1.6	-2.1
Time employed in main current job	1.0	1.1	3.9	1.1	1.3	1.1	1.4	1.2	1.1	0.9	0.9	1.4	2.0	-0.6	0.1	1.0	1.0	-0.5	0.2	-0.3
Alcohol intake versus 10 years previously	0.6	0.9	2.9	0.1	0.7	1.1	1.2	0.6	1.0	1.2	1.0	-0.7	0.2	0.6	1.7	0.8	1.5	-0.4	1.1	0.5
Father’s age at death	3.3	4.5	10.0	2.9	2.0	2.9	-1.1	2.6	2.6	2.7	2.9	0.6	0.3	0.8	3.2	2.3	1.3	1.3	2.3	-0.5
Worrier / anxious feelings	2.0	3.8	8.3	2.5	0.8	2.5	0.7	2.8	2.9	2.9	2.4	0.3	1.0	-0.3	2.2	2.9	0.5	-0.4	2.2	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.9	0.0	0.2	0.3	0.9	0.8	0.5	0.4	0.4	0.8	1.4	0.3	-0.5	0.7	1.4	0.7	0.1	0.8
Falls in the last year	0.6	0.8	2.3	1.3	0.7	0.7	1.5	1.2	0.9	0.7	0.7	0.1	0.5	0.9	0.4	0.9	0.7	-1.3	0.7	0.3
Hair/balding pattern: Pattern 3	0.7	1.1	5.9	0.4	1.2	0.1	0.2	0.1	-0.1	-0.1	-0.3	1.0	2.3	0.2	0.5	-0.1	1.0	-1.5	0.9	-2.4
Number of live births	0.2	0.3	2.3	-0.8	0.1	0.0	-0.3	0.7	0.5	0.4	0.1	0.8	0.1	-0.6	-0.3	0.8	-0.0	0.0	-0.2	1.5
Forced expiratory volume in 1-second (FEV1)	0.8	2.8	6.9	1.8	0.9	1.9	0.3	2.2	2.1	1.9	2.0	2.0	2.6	-0.5	0.6	2.2	1.6	-1.9	1.1	0.2
Pulse rate	0.7	1.2	9.8	-0.4	-0.3	-0.5	-1.5	-1.0	-0.8	-0.8	-0.3	-0.1	1.3	-1.7	-0.5	-0.9	0.3	-3.1	-0.1	-0.2
Happiness	0.6	0.7	3.7	0.9	0.4	0.5	1.1	1.3	0.8	0.9	0.2	0.2	-0.1	1.9	0.6	1.0	0.1	-0.5	0.9	0.3
Noisy workplace	1.4	1.7	8.2	0.8	1.6	1.3	0.3	1.3	1.0	0.9	1.2	0.1	2.9	0.3	1.3	0.7	1.9	-1.3	1.6	0.3
Qualifications: A levels/AS levels or equivalent	0.6	1.4	6.9	-0.5	-0.4	-1.2	-1.3	-0.9	-0.8	-0.9	-1.5	1.1	-0.8	1.3	-1.5	-0.5	-1.5	0.6	-0.9	-2.6
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	2.7	0.8	1.3	0.6	0.4	1.3	1.2	1.3	0.9	1.3	1.3	0.8	1.0	1.7	0.7	0.2	0.4	-0.2
Mouth/teeth dental problems: Dentures	0.8	1.3	10.1	0.4	1.3	0.3	3.2	0.6	0.4	0.6	0.3	-0.3	-1.0	1.1	1.8	0.3	-0.6	-0.7	1.4	-0.6
Asthma	0.4	0.8	2.3	-0.5	1.2	0.8	-0.6	0.7	0.9	1.1	0.9	1.1	0.8	-0.6	1.5	0.9	0.7	0.2	-0.0	-1.2
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.2	2.6	1.6	0.1	1.4	-0.3	1.5	1.3	1.4	1.1	0.2	-0.6	1.5	1.4	1.0	-0.7	-0.8	1.3	0.4
Medication: Cholesterol lowering	0.6	0.9	2.9	-0.6	-0.4	-0.9	0.9	-1.5	-1.4	-1.4	-0.7	-0.6	-0.7	0.0	-0.8	-1.7	-0.4	-0.6	-1.0	-0.6
Depression (self-reported)	1.3	1.5	3.6	-1.9	-0.8	-1.4	0.6	-1.3	-1.4	-1.4	-1.6	-1.2	-1.6	0.7	-1.0	-1.3	-0.6	0.3	-1.8	-0.1
Medication: Lansoprazole	0.5	0.6	3.8	-0.7	-0.2	-0.5	0.3	-0.3	-0.6	-0.5	-0.4	-0.7	-0.6	-1.9	-0.3	-0.7	-1.1	-0.7	-0.8	0.8
Prospective memory result	1.6	2.0	9.2	-0.5	-0.7	-0.5	-1.5	-0.9	-0.9	-1.0	-0.3	-2.3	1.5	-1.8	-0.7	-1.1	1.9	-1.5	-0.8	3.0
Lung cancer (father)	0.6	0.7	4.2	-1.0	0.6	-0.4	2.0	-0.6	-0.4	-0.4	-0.3	-0.2	0.3	-1.0	-0.4	-0.3	0.6	0.7	-1.3	1.4
Illnesses of mother	0.6	0.7	3.8	0.7	-2.0	0.4	1.6	0.3	0.6	0.4	0.5	0.1	-1.0	0.1	-0.7	0.3	-1.4	0.4	0.2	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.8	12.1	2.6	2.0	2.8	-0.4	3.0	2.9	2.7	2.8	2.7	3.5	-0.4	1.3	3.0	2.6	-2.8	1.6	-0.3
Pulse wave Arterial Stiffness index	0.6	0.7	5.2	0.6	-2.0	-0.1	-1.1	0.1	0.1	0.1	-0.1	-0.2	-1.3	-0.1	-0.2	-0.0	-2.3	0.3	0.3	-0.0
Impedance of arm (left)	0.1	0.5	2.1	-0.3	-1.0	-0.6	-0.1	-0.7	-0.5	-0.6	-0.6	0.1	0.2	-0.8	-1.2	-0.4	-0.5	1.4	-0.8	0.0
Arm fat mass (right)	0.3	1.2	7.5	-1.1	0.5	-0.9	-1.8	-0.6	-0.7	-0.5	-0.9	0.1	0.5	0.2	-0.2	-0.4	-0.3	-2.7	-0.7	-2.0
Trunk predicted mass	2.3	13.0	31.4	3.1	4.6	3.4	-0.3	4.0	3.6	3.8	3.5	2.3	5.1	0.9	3.6	4.0	5.6	-4.5	3.3	-0.0
Standing height	3.7	36.9	97.4	6.4	7.1	6.2	0.1	6.8	6.3	6.4	6.3	3.6	8.7	1.0	5.8	6.5	9.9	-5.4	6.1	1.2
Length of working week for main job	0.9	1.0	7.1	1.2	0.1	-0.1	-0.6	-0.0	-0.1	0.1	-0.3	-0.2	-0.5	1.3	1.2	-0.2	-0.9	-1.5	-0.9	-2.7
Exposure to tobacco smoke at home	0.8	0.9	2.6	-1.1	-0.8	-1.3	1.0	-0.9	-0.7	-0.8	-1.2	0.8	0.2	-1.4	-1.2	-0.2	-1.6	-0.9	-0.3	0.5
Breastfed as a baby	0.3	0.3	1.9	0.4	0.8	0.4	-0.7	0.7	0.5	0.5	0.1	-0.4	0.2	-0.2	0.6	0.6	0.2	-1.4	0.0	0.5
Tense / ‘highly strung’	0.2	0.3	1.0	-0.2	-0.7	0.0	-0.4	0.5	0.4	0.4	-0.0	0.3	0.5	-0.1	-0.3	0.5	-0.7	-1.0	0.9	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	3.8	-1.4	-1.4	-0.6	0.7	-0.8	-0.8	-0.7	-0.9	-1.4	-1.4	1.1	-0.4	-1.1	-0.9	1.9	0.1	1.5
Hair/balding pattern: Pattern 4	0.3	0.7	2.5	0.5	-0.2	0.9	-0.1	1.0	1.0	1.0	1.1	0.4	-0.2	1.6	1.0	0.7	-0.1	-0.7	1.2	-0.1
Birth weight of first child	1.0	1.9	5.2	-2.3	-0.6	-1.3	0.9	-1.9	-1.7	-1.8	-1.5	-1.5	0.3	-1.3	-1.5	-1.9	0.2	-0.8	-1.3	-0.2
Peak expiratory flow (PEF)	0.5	1.2	4.0	2.0	0.4	1.6	-1.8	1.1	1.2	1.1	1.6	0.8	0.8	0.2	0.7	0.9	0.4	-0.1	0.5	0.6
Pulse wave reflection index	0.7	0.9	2.6	-0.1	-1.5	-0.4	1.2	-0.3	-0.4	-0.5	-0.7	-0.6	-1.6	1.4	-0.6	-0.6	-1.6	0.7	-0.9	-0.5
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.8	0.4	0.3	1.2	-1.3	1.0	1.1	1.0	1.1	0.9	1.2	0.0	0.5	1.1	0.2	-0.3	0.4	-0.3
Loud music exposure frequency	0.9	0.9	4.5	-0.2	0.2	0.9	1.1	0.6	0.9	0.7	0.9	-1.2	-0.7	-1.1	0.2	0.7	0.1	1.9	-0.2	2.1
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	4.8	0.2	0.3	0.7	-2.2	0.7	0.7	0.5	0.4	0.9	0.1	-0.6	-0.4	0.6	-1.0	1.4	0.3	-0.7
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	2.3	0.8	0.1	1.3	-0.5	0.3	0.5	0.5	1.5	-0.5	0.6	0.4	1.5	-0.2	0.4	-0.9	1.3	-0.0
Blood clot in the leg (DVT)	0.4	0.5	2.1	-0.7	-0.6	0.1	0.0	0.4	0.5	0.4	0.5	0.6	1.0	-1.2	-0.3	0.6	-0.5	-1.1	0.7	1.4
Medication: Paracetamol	0.3	0.5	1.8	0.2	0.8	1.1	-0.3	0.8	0.8	0.9	0.8	0.0	0.4	0.6	1.3	0.4	-0.1	-0.1	0.8	-1.2
Headache pain in last month	0.5	0.8	3.6	-0.2	0.2	0.7	0.9	0.6	0.6	0.6	0.7	0.0	1.1	0.4	0.0	0.6	0.8	-1.9	1.3	1.9
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	5.1	0.6	-0.7	0.8	0.4	1.4	1.3	1.3	0.7	0.2	-0.5	0.2	0.6	1.4	-0.8	2.2	0.7	0.8
Glaucoma (self-reported)	0.8	1.0	2.9	1.2	1.5	0.7	0.4	0.9	0.9	0.9	0.9	1.3	1.7	0.6	0.5	1.1	1.7	-0.4	0.2	-0.2
Gout (self-reported)	0.3	0.4	2.3	-0.3	-0.2	-0.6	-0.6	-0.5	-0.2	0.0	-0.3	0.2	-0.8	0.3	0.7	0.0	-1.0	0.5	-0.9	-1.5
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.6	-0.9	0.1	-1.4	-0.3	-0.7	-0.9	-1.0	-1.3	-0.9	1.2	-1.6	-1.4	-0.4	-0.6	-0.2	-1.3	0.5
Medication: Amlodipine	2.0	2.8	8.3	0.9	1.9	1.1	-0.2	1.4	1.3	1.2	1.5	2.8	2.9	1.4	0.3	1.7	2.0	-2.4	1.8	-1.2
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.9	-0.8	0.1	-0.7	-1.4	-0.4	-0.5	-0.3	-0.6	-0.6	-1.2	0.2	0.3	-0.4	-1.4	1.0	-0.4	-0.6
Birth weight	0.4	0.8	3.1	-0.9	1.7	-0.5	1.3	-0.1	-0.4	-0.4	-0.5	-0.5	0.2	-0.9	-0.3	-0.2	1.8	1.0	-1.5	0.2
Chronic bronchitis/emphysema (mother)	0.6	0.7	5.0	-1.0	0.9	-0.2	0.4	0.0	0.1	0.2	-0.4	0.1	-1.2	1.5	0.6	0.4	0.6	2.2	-0.1	0.8
High blood pressure (siblings)	0.2	0.3	0.5	-0.2	0.2	-0.7	-0.4	-0.7	-0.7	-0.7	-0.6	-0.0	0.4	0.1	-0.4	-0.7	0.4	-0.5	-0.2	-0.7
Forced vital capacity (FVC), Best measure	3.1	11.3	22.8	3.7	4.0	3.7	-0.2	4.0	3.9	3.8	3.7	2.9	4.8	-0.6	2.3	4.1	4.6	-3.0	2.5	0.1
Body fat percentage	0.6	2.2	5.6	-1.7	-0.5	-1.9	-2.1	-1.5	-1.7	-1.5	-1.9	0.1	-0.1	-0.0	-1.3	-1.3	-1.6	-1.9	-0.9	-2.4
Leg fat percentage (right)	1.3	4.6	9.2	-2.8	-1.5	-3.0	-1.8	-2.3	-2.6	-2.4	-2.9	-0.9	-1.4	-0.1	-2.0	-2.0	-3.0	-1.6	-1.5	-2.2
Arm fat-free mass (right)	2.1	10.6	20.2	3.0	4.0	3.2	-0.6	3.7	3.4	3.6	3.3	2.1	4.1	0.8	3.6	3.5	4.5	-4.0	3.2	-0.8
Exposure to tobacco smoke outside home	0.3	0.4	1.8	-0.9	0.2	-0.5	1.3	-0.1	-0.1	-0.2	-0.5	0.1	1.3	0.0	-0.8	0.3	0.0	-0.3	-0.8	1.0
Comparative body size at age 10	2.8	7.7	14.3	-3.5	-2.5	-3.4	-1.1	-3.8	-3.6	-3.6	-3.4	-2.4	-2.1	-1.0	-2.6	-3.7	-2.8	0.9	-2.8	0.1
Number of full brothers	3.2	4.1	7.3	-2.5	-2.6	-2.2	-1.8	-2.1	-2.5	-2.6	-2.2	-0.8	-1.6	-1.3	-2.4	-2.7	-1.5	-1.0	-1.6	-1.0
Worry too long after embarrassment	0.4	0.7	2.1	0.5	-1.5	0.3	-1.2	0.8	0.8	0.6	0.4	0.7	-0.5	1.3	-0.7	0.7	-1.3	0.2	1.3	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	2.0	-0.1	-0.1	0.1	1.1	-0.2	-0.2	-0.2	0.1	-0.3	-1.3	1.4	-0.1	-0.4	0.0	0.5	0.6	1.1
Wheeze or whistling in the chest in last year	0.4	0.7	2.1	0.5	1.2	0.5	-1.1	0.8	0.6	0.8	0.6	0.3	0.1	-0.7	1.1	0.7	-0.4	-1.4	0.7	-1.0
Number of children fathered	0.2	0.3	1.9	-0.2	-0.5	-0.6	0.6	-0.0	-0.5	-0.4	-0.5	-0.0	-0.2	-0.5	-0.3	-0.4	-0.2	1.4	-0.3	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	3.2	3.7	6.1	2.4	2.5	2.1	-0.1	2.2	2.3	2.3	1.9	0.8	2.1	1.0	2.3	2.3	2.1	-1.6	2.1	-0.3
Age at first live birth	0.4	0.7	3.1	0.2	1.0	-0.3	-1.6	-0.2	-0.1	-0.0	-0.4	-0.1	1.1	-0.4	0.0	0.2	1.8	-1.3	0.5	-1.0
Pulse wave peak to peak time	1.0	1.2	8.8	-0.0	2.4	0.5	1.1	0.3	0.3	0.3	0.6	0.1	1.7	0.1	0.6	0.4	3.0	-0.5	0.1	0.3
Health satisfaction	0.2	0.2	1.4	-0.3	0.6	-0.3	-0.5	0.2	0.2	0.2	-0.1	0.6	0.8	0.1	-0.2	0.6	0.5	-1.2	-0.1	-0.2
Shortness of breath walking on level ground	0.5	0.6	3.0	0.3	0.2	0.1	-0.1	0.9	0.9	0.9	-0.0	1.7	0.9	0.4	0.3	1.4	-0.7	-1.2	-0.2	-0.1
Qualifications: College or University degree	0.3	1.0	4.9	-1.0	1.1	-0.5	-2.2	-0.4	-0.3	-0.2	-0.8	1.0	-0.8	1.9	-0.4	0.3	0.4	0.9	-1.0	-0.9
Eye problems/disorders: None of the above	1.3	1.5	4.7	-1.6	-1.9	-0.7	-1.4	-1.0	-1.0	-1.0	-0.8	-0.6	-2.2	0.1	-1.1	-1.2	-1.6	1.6	-0.3	0.4
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.1	0.2	0.7	0.5	0.7	0.3	0.2	0.1	0.3	0.2	0.7	0.3	0.3	0.0	1.0	-0.7	0.8	1.1
Emphysema/chronic bronchitis	0.4	0.4	2.2	0.3	0.8	0.9	-1.5	0.5	0.6	0.5	0.9	0.3	0.9	0.5	0.1	0.4	0.8	0.2	0.2	-0.5
Medication for pain relief, constipation, heartburn	0.2	0.3	1.1	-0.4	0.1	-0.7	0.1	-0.2	-0.3	-0.2	-0.4	-0.6	-0.5	-0.2	-0.1	0.1	0.7	1.0	-0.9	0.7
Neck or shoulder pain in last month	0.9	1.2	5.9	1.0	1.1	0.2	-1.5	0.3	0.3	0.3	0.2	1.7	2.3	-0.7	-0.4	0.5	0.7	-2.4	-0.1	-0.5
Medication: Blood pressure	0.6	1.1	9.5	0.6	1.2	0.2	-1.1	-0.4	-0.2	-0.2	0.4	0.1	1.6	-0.4	0.3	-0.4	1.4	-3.1	0.3	-0.7
Angina (self-reported)	0.6	0.8	5.9	-1.4	-0.1	-0.7	2.4	-0.8	-0.8	-0.8	-0.7	-0.1	0.6	0.3	-0.9	-0.8	-0.2	-0.7	0.0	0.3
Migraine (self-reported)	2.1	2.6	4.9	-1.6	-0.5	-2.0	0.2	-1.9	-1.9	-2.0	-2.2	-1.6	-0.8	-2.0	-2.2	-1.7	-0.7	-0.8	-2.1	-0.0
Medication: Ibuprofen	1.5	1.7	4.1	1.8	-0.1	1.6	-0.6	2.0	1.8	1.9	1.3	0.7	-0.4	1.7	1.7	1.6	-0.7	-0.4	1.4	0.2
Medication: Allopurinol	0.8	1.0	3.6	-0.9	-0.8	-1.0	-1.9	-1.4	-1.0	-0.8	-0.6	-0.2	-0.9	-0.1	0.1	-1.0	-1.2	0.5	-1.2	-1.7
Medication: Omeprazole	0.5	0.6	1.4	1.2	-0.4	0.6	-0.5	1.2	0.9	0.9	0.5	0.8	-1.1	0.5	0.1	1.1	-0.6	0.3	0.3	0.8
Medication: Seretide 50 evohaler	0.6	0.7	1.8	0.5	1.3	0.9	-0.8	0.8	0.7	0.7	0.8	0.7	1.0	-0.2	0.7	0.6	0.5	-0.6	1.3	-1.2
Mean time to correctly identify matches	1.9	3.6	17.2	1.1	2.1	1.0	-2.1	0.7	0.9	0.9	1.1	1.8	3.0	0.7	1.6	0.7	3.3	-4.2	1.4	-1.1
Heart disease (mother)	0.4	0.4	2.2	-0.6	1.5	-0.1	0.1	-0.3	-0.4	-0.2	-0.2	0.1	0.7	0.9	1.4	-0.5	1.0	-0.3	0.2	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.4	3.8	-0.4	-1.6	-1.6	-1.3	-1.2	-1.3	-1.3	-2.0	-1.5	-0.5	0.1	-1.1	-1.2	-1.3	-0.3	0.3	-0.6
Whole body fat mass	0.3	1.3	9.6	-0.6	1.0	-0.6	-1.8	-0.1	-0.3	-0.1	-0.6	0.7	1.3	0.3	0.1	0.1	0.3	-3.1	0.2	-2.0
Leg fat mass (right)	0.3	1.3	8.7	-1.2	0.3	-1.2	-1.5	-0.6	-0.8	-0.6	-1.1	0.3	0.3	0.2	-0.3	-0.4	-0.8	-3.0	-0.1	-2.0
Arm predicted mass (right)	2.0	10.5	20.2	3.1	4.1	3.0	-0.7	3.6	3.2	3.5	3.2	2.0	4.2	0.9	3.6	3.4	4.5	-4.3	3.4	-0.8
Pulse rate, automated reading	0.3	1.0	7.5	-0.4	0.9	-0.3	-1.1	-0.5	-0.3	-0.3	-0.3	0.9	1.7	0.0	0.0	-0.1	1.5	-2.7	0.3	-0.8
Alcohol intake frequency.	0.9	2.0	7.6	-1.4	-1.5	-1.1	0.8	-1.5	-1.4	-1.2	-1.2	-2.4	-2.8	0.1	0.1	-1.7	-1.5	0.5	-0.3	1.2
Comparative height size at age 10	2.4	13.3	52.3	3.9	4.6	3.3	0.7	3.4	3.1	3.2	3.6	1.1	6.0	0.3	3.1	3.3	7.2	-3.5	3.3	0.9
Number of full sisters	0.4	0.5	1.4	0.2	0.6	0.6	1.2	1.0	0.7	0.8	0.6	0.1	0.2	-1.1	1.0	0.8	0.6	-0.5	0.2	-0.8
Suffer from ‘nerves’	0.5	0.8	2.1	0.6	1.5	0.6	1.3	0.7	0.8	0.8	0.7	1.0	1.4	0.0	0.6	1.0	1.0	-0.6	0.7	0.3
Overall health rating	0.3	0.7	8.2	-0.1	0.0	0.0	1.0	0.2	0.2	0.1	0.2	0.9	1.4	0.1	-0.3	0.3	0.3	-2.9	0.3	0.1
Chest pain or discomfort	0.3	0.4	2.1	-0.1	-1.1	0.4	-0.0	0.3	0.3	0.2	0.3	0.8	-0.5	0.4	-0.4	-0.0	-1.4	-0.5	0.4	-1.4
Had major operations	0.6	0.8	4.8	-1.0	0.5	0.2	-0.6	-0.7	-0.3	-0.3	-0.0	0.1	0.4	0.4	0.5	-0.6	0.1	-2.2	-0.4	-2.2
Age at last live birth	0.5	0.8	3.3	0.5	0.5	0.8	-0.8	0.6	0.6	0.5	0.7	0.6	1.6	1.2	-0.0	0.5	1.8	-1.2	0.4	-0.5
Family relationship satisfaction	3.9	4.7	9.0	2.0	3.0	2.3	0.0	2.4	2.4	2.5	2.2	1.1	1.8	2.4	2.8	2.4	2.9	1.1	2.4	-0.2
Leg pain on walking	0.6	0.8	3.1	0.8	0.4	0.9	1.1	0.6	0.8	0.9	0.8	-0.0	0.3	-0.1	1.3	0.7	0.7	-1.0	1.1	1.8
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	4.3	0.8	0.2	0.6	-0.5	0.3	0.5	0.7	0.6	-1.7	-0.8	-2.1	1.9	0.1	-0.9	0.3	0.2	-0.3
Commuting to job workplace: Car/motor vehicle	0.9	1.0	3.0	0.8	0.8	1.1	-0.3	1.0	1.2	1.1	1.1	0.5	1.5	0.3	1.2	1.1	0.3	-1.7	1.0	-0.2
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	2.4	-0.6	-1.3	-0.9	-0.9	-0.6	-1.0	-1.1	-1.0	0.2	-0.7	-0.1	-1.5	-1.0	-1.3	-0.7	-0.7	-1.0
Medication: Aspirin	0.3	0.4	1.7	0.5	0.5	0.3	1.3	-0.4	-0.1	-0.2	0.3	0.3	0.9	1.0	-0.1	-0.3	0.3	-0.9	0.7	-0.3
Supplements: Vitamin C	0.5	0.6	1.4	1.0	0.8	0.8	0.9	0.7	0.9	1.0	0.8	0.2	0.5	0.2	0.6	1.1	0.5	1.0	0.2	1.2
Knee pain experienced in last month	0.5	0.8	5.1	1.3	-0.4	0.9	2.3	0.6	0.4	0.5	0.7	-1.1	-0.1	1.0	1.1	-0.1	-0.2	-0.6	1.1	0.1
Hypertension (Self-reported)	0.8	2.2	17.7	0.5	1.5	0.2	-0.9	0.6	0.5	0.5	0.3	1.9	2.5	-0.4	0.2	0.9	1.3	-4.2	0.2	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	4.6	0.3	-1.2	-0.1	-0.3	0.3	0.2	-0.0	-0.2	-0.0	-0.7	-1.6	-1.1	0.2	-2.1	1.8	-0.1	0.8
Illnesses of father: Heart disease	1.4	2.0	4.9	-1.1	-1.6	-1.8	-0.2	-1.4	-1.6	-1.5	-1.8	-0.8	-0.5	-1.6	-1.6	-1.4	-2.2	-1.4	-1.1	-0.2
Illnesses of siblings: Diabetes	1.1	1.3	7.1	-0.4	0.8	1.0	-0.3	0.2	0.6	0.7	1.0	1.4	0.5	2.7	1.7	0.2	1.7	-1.0	0.4	-1.6
Smoking status: Previous	1.2	1.9	3.9	2.0	0.7	1.7	-1.2	1.3	1.5	1.5	1.6	0.1	0.2	1.6	1.9	1.0	0.6	-1.6	1.8	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	2.1	4.4	12.0	2.0	2.9	2.4	-1.2	2.5	2.3	2.4	2.5	1.0	2.3	0.2	2.4	2.2	3.5	-0.9	1.4	-0.4
Whole body fat-free mass	2.3	13.1	28.0	3.2	4.7	3.5	-0.7	4.0	3.7	3.9	3.6	2.6	5.1	1.0	3.7	4.0	5.3	-4.5	3.3	-0.7
Leg fat-free mass (right)	2.0	10.9	21.5	2.8	4.3	3.3	-0.7	3.6	3.4	3.5	3.4	2.9	4.6	1.1	3.3	3.6	4.6	-3.8	2.7	-1.1
Arm fat percentage (left)	0.9	3.6	7.2	-2.5	-1.0	-2.4	-1.6	-2.2	-2.2	-2.0	-2.4	-0.3	-1.1	0.3	-1.7	-1.8	-2.3	-1.4	-2.0	-2.7
Average weekly red wine intake	0.8	1.2	3.1	-1.3	-0.2	-1.2	-1.8	-1.4	-1.3	-1.3	-1.5	-1.0	-0.2	-0.7	-1.2	-1.0	-0.6	0.3	-1.4	0.1
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.4	-0.2	-0.5	-0.8	0.9	-0.9	-0.8	-0.7	-0.9	-0.9	-0.3	-0.8	-0.8	-0.6	-0.1	0.2	-1.2	0.1
Mood swings	1.2	2.2	4.5	1.8	0.2	1.8	1.4	2.1	2.0	1.9	1.8	0.8	1.3	1.1	1.0	1.9	1.1	-0.6	2.1	-0.0
Loneliness, isolation	1.2	1.6	4.0	0.7	0.0	1.5	0.9	1.6	1.7	1.9	1.4	0.8	0.2	0.6	2.0	1.6	0.3	0.9	2.0	0.0
Long-standing illness, disability or infirmity	0.8	1.2	3.7	-1.4	0.8	-1.3	-0.6	-1.2	-1.2	-1.2	-1.1	-0.3	0.5	-0.4	-0.5	-1.0	0.0	-1.6	-1.9	-1.3
Ever had bowel cancer screening	0.3	0.3	1.0	0.9	0.5	0.4	0.2	0.7	0.5	0.5	0.4	0.9	1.0	0.1	0.7	0.5	0.3	-0.6	0.2	0.3
Diabetes diagnosed by doctor	0.2	0.3	1.6	0.0	0.4	-0.5	0.2	-0.7	-0.7	-0.6	-0.6	-0.9	0.2	-0.1	-0.4	-0.7	0.8	-1.3	-0.0	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	1.4	0.3	0.3	0.0	1.0	0.0	0.2	0.1	-0.0	0.5	0.8	1.2	-0.5	0.2	-0.2	0.1	0.5	0.7
Friendships satisfaction	3.4	4.2	11.5	1.3	2.5	2.1	0.4	3.0	2.9	2.9	1.8	1.7	0.9	1.6	1.9	3.4	1.8	1.5	1.7	0.5
Qualifications: nursing, teaching	0.7	1.1	3.5	-1.9	-1.4	-0.9	0.2	-1.1	-1.1	-1.1	-1.0	-1.1	-0.4	1.2	-1.1	-1.2	-1.2	0.4	-0.2	-0.2
Commuting to job workplace: Walk	0.3	0.3	2.2	0.2	0.2	0.1	-0.8	0.1	0.2	0.2	0.3	-0.0	0.0	0.1	-0.3	0.3	0.6	1.4	-0.2	1.5
Eye problems/disorders: Cataract	0.3	0.4	2.1	0.6	0.9	-0.2	-0.2	-0.1	-0.1	-0.1	-0.0	0.2	1.4	-1.0	0.1	0.1	0.3	-1.1	-0.4	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	2.0	-1.4	0.9	-1.1	-0.7	-0.6	-0.7	-0.6	-1.1	-0.4	0.1	0.8	-0.4	-0.2	-0.0	0.0	-0.9	0.2
Medication for cholesterol	0.8	1.3	5.9	-0.5	0.5	0.3	2.4	0.0	0.2	0.2	0.3	-1.6	-1.1	0.3	1.2	-0.2	1.2	1.6	1.2	2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.7	4.7	-1.2	-1.6	-0.9	-1.5	-1.7	-1.6	-1.8	-0.8	-1.6	0.7	-0.9	-1.2	-2.2	0.2	0.4	-0.5	1.4
Back pain experienced in last month	0.3	0.4	2.4	-0.3	-0.5	-0.2	-0.2	-0.3	-0.4	-0.6	-0.1	-0.6	0.5	-1.0	-1.0	-0.5	-0.2	-1.6	-0.1	0.9
Mineral and other dietary supplements	0.3	0.4	2.1	-0.3	-1.0	-0.4	-0.4	-0.6	-0.5	-0.5	-0.3	-0.2	-1.1	-0.2	-0.4	-0.6	-1.4	-0.8	-0.2	-0.2
Breast cancer (self-reported)	0.1	0.2	1.2	0.5	0.4	-0.1	-1.1	-0.1	-0.1	-0.0	-0.1	0.0	0.4	-0.7	-0.1	0.1	-0.4	0.0	-0.3	-0.1
Asthma (self-reported)	0.7	1.4	3.2	-0.2	1.6	1.1	-0.9	1.1	1.3	1.5	1.3	1.7	1.3	-0.3	1.8	1.4	1.1	-0.4	0.3	-1.2
Osteoporosis (self-reported)	0.5	0.6	1.5	0.3	-0.2	1.1	0.1	0.7	1.0	1.0	1.2	0.4	-0.5	-0.1	0.9	0.7	0.5	1.2	0.9	0.4
Osteoarthritis (self-reported)	2.7	3.5	6.9	-1.7	-0.3	-2.6	-0.9	-2.6	-2.5	-2.4	-2.3	-2.1	-0.7	-1.5	-0.8	-2.2	-0.8	-2.3	-2.2	-1.3
Medication: Aspirin	0.3	0.4	2.3	0.7	0.5	0.6	1.5	-0.3	0.1	-0.0	0.6	0.5	0.9	0.8	-0.0	-0.3	0.5	-0.9	0.6	-0.7
Medication: Gliclazide	0.2	0.2	0.9	0.1	-0.4	0.0	0.6	-0.5	-0.4	-0.3	-0.0	-0.5	-0.1	0.3	0.3	-0.7	0.7	-1.0	0.0	-0.5
Illnesses of father: None of the above (group 1)	1.0	1.3	5.9	0.6	-0.3	0.8	2.2	0.7	0.6	0.6	0.8	-1.3	-1.2	0.5	0.6	0.2	0.6	2.4	1.1	1.6
Smoking status: Current	0.2	0.3	2.3	-0.2	-0.2	-0.3	0.3	-0.2	-0.4	-0.4	-0.2	-0.6	-0.7	1.5	-0.3	-0.3	0.3	0.5	0.4	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	4.1	0.2	0.3	0.1	-0.5	0.4	0.5	0.4	0.3	2.0	1.0	-0.0	-0.6	0.9	-0.3	-1.0	-0.7	-0.9
Whole body water mass	2.2	12.8	27.2	3.1	4.5	3.4	-0.7	3.9	3.6	3.8	3.5	2.5	5.0	1.0	3.6	3.9	5.2	-4.4	3.3	-0.6
Leg predicted mass (right)	2.0	10.9	21.8	2.8	4.3	3.3	-0.7	3.6	3.5	3.5	3.4	2.9	4.7	1.1	3.3	3.6	4.6	-3.8	2.7	-1.1
Arm fat mass (left)	0.3	1.2	6.4	-1.3	0.4	-1.1	-1.6	-0.7	-0.8	-0.6	-1.0	0.0	0.3	0.2	-0.2	-0.5	-0.5	-2.5	-0.8	-2.1
Number of self-reported non-cancer illnesses	1.0	1.7	9.4	-0.6	0.5	-1.3	-1.4	-0.7	-0.7	-0.7	-1.2	1.1	2.2	-0.3	-0.9	-0.2	-0.4	-3.1	-1.5	-2.0
Average weekly champagne plus white wine intake	0.5	0.7	2.5	-0.8	-0.9	-0.8	-1.5	-0.6	-0.8	-0.8	-0.8	-1.6	-0.9	-0.7	-0.3	-0.8	-0.2	1.0	-0.6	0.3
Miserableness	0.5	0.9	6.0	0.2	-2.4	-0.3	0.7	0.1	-0.1	-0.2	-0.2	-0.7	-1.2	0.6	-1.0	-0.2	-1.8	1.3	-0.3	-1.0
Guilty feelings	0.3	0.5	1.8	0.3	-0.7	-0.2	1.3	0.7	0.5	0.6	0.2	-0.1	0.6	-0.5	-0.3	0.9	-0.2	0.4	1.2	1.0
Wears glasses or contact lenses	0.2	0.2	1.1	0.1	0.5	-0.2	-0.9	-0.1	-0.3	-0.2	-0.2	-0.5	0.1	0.1	0.6	-0.4	1.0	-0.7	0.5	0.1
Ever taken oral contraceptive pill	0.8	0.9	3.3	0.3	0.8	0.9	1.8	0.3	0.6	0.5	0.9	1.4	0.9	1.3	0.3	0.5	1.1	-0.6	1.4	-0.9
Hearing aid user	1.6	1.8	4.6	0.8	1.4	1.5	-1.2	1.4	1.4	1.5	1.7	0.3	1.1	0.4	2.0	1.2	2.1	-0.4	0.8	-1.7
Mother’s age at death	1.8	2.2	4.3	-1.9	-1.5	-1.6	0.2	-1.6	-1.6	-1.7	-1.4	-1.7	-1.2	-2.1	-1.4	-1.7	-1.9	0.1	-1.2	0.8
Financial situation satisfaction	1.5	1.8	3.9	0.7	1.8	1.2	2.0	1.7	1.6	1.6	1.2	0.3	1.2	0.5	1.6	1.8	0.8	-1.3	1.1	0.9
Tinnitus: Yes, now most or all of the time	1.4	1.6	3.9	0.6	0.9	1.0	-1.2	1.6	1.6	1.5	1.3	1.8	1.4	0.1	0.3	2.0	1.1	-0.2	1.8	1.3
Commuting to job workplace: Public transport	0.9	1.0	7.5	0.5	-0.1	0.3	1.8	0.8	0.7	0.7	0.0	0.5	-1.4	0.7	0.1	0.9	-1.0	2.7	0.4	0.6
Eye problems/disorders: Glaucoma	1.5	1.7	5.1	1.7	2.1	1.1	1.3	1.0	1.1	1.1	1.2	1.1	2.0	-0.3	0.8	1.3	2.3	-0.9	0.2	0.3
Medication: Blood pressure	0.7	1.3	7.8	0.1	0.2	-0.4	-1.5	-0.3	-0.3	-0.3	-0.5	1.5	1.3	-0.6	-0.5	-0.1	-0.3	-2.8	-1.1	-2.4
Pain type(s) experienced in last month: Hip pain	0.4	0.5	4.0	-0.2	1.2	-0.1	-1.5	0.0	-0.1	-0.0	0.2	-0.3	-0.7	-0.3	0.5	0.0	0.5	2.0	-0.1	0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.2	-0.1	0.7	-0.3	1.0	0.0	-0.1	-0.1	-0.4	-0.4	0.4	0.1	0.1	0.1	0.8	1.1	-0.6	-0.3
High cholesterol (Self-reported)	0.2	0.3	1.6	1.2	-0.8	0.5	-0.1	0.3	0.2	0.1	0.5	0.2	-0.1	0.9	-0.1	-0.2	-0.8	-0.3	0.1	-0.5
Medication: Bendroflumethiazide	0.7	1.1	8.9	0.3	-0.2	-0.6	-1.0	-0.5	-0.8	-0.8	-0.8	-0.7	0.7	-1.8	-0.9	-0.8	0.4	-3.0	-0.5	-0.0
Medication: Paracetamol	1.0	1.5	3.7	0.9	1.1	1.9	-0.7	1.6	1.5	1.5	1.7	0.7	0.9	0.4	1.8	0.9	0.5	-0.9	1.1	-1.2
Medication: Lisinopril	0.8	1.0	2.3	0.3	-0.7	-1.0	-1.2	-1.4	-1.4	-1.4	-0.9	-0.9	0.8	-1.1	-1.1	-1.5	-0.3	-0.5	-0.5	-0.7
Medication: Atorvastatin	1.1	1.4	5.4	-1.2	-0.4	-1.6	1.2	-0.9	-1.0	-1.0	-1.6	0.5	0.2	-0.3	-1.6	-0.4	-1.2	-2.3	-1.0	-1.0
Illnesses of father: High blood pressure	0.4	0.5	1.7	-0.7	-0.6	-0.7	-1.3	-0.7	-0.5	-0.6	-0.9	0.1	-0.1	-0.2	-1.1	-0.2	-0.5	-0.3	-1.3	-0.9
Alcohol drinker status: Never	1.1	1.3	8.0	-0.5	-0.2	-0.2	1.1	-0.4	-0.3	-0.3	-0.5	-2.8	-0.9	-1.4	0.2	-0.6	-0.1	0.5	0.8	2.8
Ever smoked	1.9	3.3	11.4	1.4	0.5	2.0	-2.0	2.1	2.0	2.0	1.9	1.4	-0.1	3.4	1.9	1.8	0.3	-0.8	2.0	-2.4
Basal metabolic rate	1.9	10.7	22.5	2.8	4.2	3.0	-0.8	3.5	3.2	3.4	3.1	2.3	4.7	1.0	3.3	3.5	4.7	-4.5	2.9	-1.0
Leg fat percentage (left)	1.0	3.7	7.6	-2.6	-0.8	-2.8	-1.7	-2.1	-2.4	-2.1	-2.7	-0.4	-1.2	0.2	-1.5	-1.8	-2.4	-1.6	-1.3	-2.3
Arm fat-free mass (left)	2.1	10.6	20.3	3.0	4.0	3.2	-0.7	3.7	3.4	3.6	3.2	1.8	4.2	0.8	3.6	3.5	4.5	-4.2	3.4	-0.5
Number of operations (self-reported)	0.7	1.1	3.8	-1.5	0.0	-1.3	-2.0	-1.1	-1.1	-0.9	-1.4	-0.2	-0.3	0.2	-0.3	-0.7	-0.9	-0.4	-0.9	-1.6
Average weekly beer plus cider intake	1.4	2.0	5.2	1.0	1.1	1.4	1.8	2.0	2.1	2.0	1.7	2.1	0.3	0.6	1.1	2.3	-0.1	-0.6	0.8	-0.0
Irritability	0.3	0.6	3.0	-0.8	-0.1	-0.5	1.1	-0.3	-0.4	-0.4	-0.7	0.2	1.0	1.1	-0.5	-0.3	-0.8	-1.7	0.4	-0.7
Risk taking	1.1	1.6	6.9	0.4	0.8	1.2	0.9	1.4	1.4	1.3	1.0	1.1	2.6	0.4	0.5	1.5	1.4	-1.5	1.3	-0.0
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.5	1.1	0.3	0.6	-0.7	0.2	0.2	0.1	0.4	0.2	0.0	-0.1	0.1	-0.0	0.8	-0.8	0.4	1.2
Fractured/broken bones in last 5 years	0.4	0.5	1.8	0.2	0.4	0.3	-0.7	1.0	0.8	0.8	0.6	0.7	1.0	0.1	-0.5	1.3	0.1	-1.0	0.4	0.4
Age started oral contraceptive pill	1.8	2.3	9.6	1.2	2.6	1.4	0.2	1.1	1.2	1.3	1.4	-0.2	1.5	0.5	2.0	1.1	3.1	0.1	1.7	1.1
Diastolic blood pressure, automated reading	0.8	2.6	7.6	-1.8	-1.4	-2.1	-2.1	-1.0	-1.2	-1.1	-2.0	1.2	-1.0	-1.2	-1.9	-0.5	-2.8	-2.0	-0.7	-1.9
Ever depressed for a whole week	0.5	0.6	3.9	-0.2	0.7	0.2	-0.1	-0.1	-0.0	-0.0	0.1	1.4	0.0	2.0	-0.2	0.1	0.3	-0.6	-1.6	-0.9
Unable to work because of sickness or disability	0.4	0.5	2.2	-0.8	-0.7	0.1	-0.7	-0.5	-0.2	-0.1	0.3	0.4	0.3	1.5	0.6	-0.5	1.0	-0.8	-0.2	-1.3
Commuting to job workplace: Cycle	0.1	0.2	0.5	0.5	-0.2	-0.1	0.1	-0.1	-0.3	-0.2	0.1	-0.4	-0.6	0.2	0.4	-0.4	-0.6	-0.3	-0.7	-0.7
Myopia	0.3	0.5	2.3	-0.3	-0.8	0.5	-1.5	-0.0	0.0	-0.1	0.5	1.0	-0.8	-0.4	-0.8	-0.2	-0.0	1.1	0.2	0.7
Vascular/heart problems diagnosed by doctor	0.7	2.0	17.5	0.1	-1.3	0.2	1.1	0.0	0.1	0.0	0.1	-1.6	-2.3	0.8	0.1	-0.2	-1.1	4.2	0.2	1.7
Cholesterol lowering medication	0.2	0.4	1.2	0.1	-0.8	-0.2	-0.9	0.4	0.1	0.1	-0.2	0.7	1.1	0.4	-1.1	0.3	-1.0	-0.3	-0.3	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	2.7	0.8	-1.1	0.3	-1.6	0.8	0.6	0.5	0.1	1.1	-1.5	-0.9	-0.3	0.7	-1.5	0.1	-0.4	0.1
Pain experienced in last month	0.2	0.3	1.9	-0.4	0.7	-0.2	-0.2	0.2	0.2	0.4	-0.2	0.4	-0.2	0.4	0.6	0.6	0.2	1.4	-0.9	-0.9
Supplements: Calcium	0.6	0.6	3.8	0.8	0.5	0.3	1.9	0.5	0.6	0.7	0.2	0.3	-0.2	1.6	0.8	0.7	-0.3	-0.5	-0.6	0.5
Basal cell carcinoma (self-reported)	1.5	1.8	6.6	-2.3	-0.6	-1.6	2.6	-1.9	-1.7	-1.6	-1.4	-0.8	-0.3	0.3	-0.4	-1.7	-0.6	-0.4	-1.1	-0.3
Heart attack/myocardial infarction (self-reported)	1.7	2.2	12.5	-1.3	-0.1	-1.4	3.5	-2.0	-1.8	-1.8	-1.2	0.2	0.1	0.2	-1.6	-1.7	-0.6	-1.1	-1.6	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.2	-0.5	-0.5	0.1	-0.3	0.4	0.5	0.4	0.5	0.5	1.0	-1.1	-0.3	0.6	-0.1	-0.9	0.7	1.5
Heart disease (siblings)	0.9	1.1	3.0	-1.7	-0.1	-1.2	1.4	-1.1	-1.1	-1.1	-1.2	0.5	-0.0	-0.4	-1.4	-0.9	-0.3	-1.5	-0.9	-1.1
Alcohol drinker status: Previous	0.4	0.4	2.2	-1.0	-0.2	-0.5	-1.5	-0.3	-0.3	-0.0	-0.6	-0.8	-0.9	-0.1	0.4	-0.1	-0.8	-0.7	-0.3	0.3
Pack years of smoking	1.7	2.6	5.2	1.5	2.2	1.6	0.1	1.3	1.4	1.3	1.4	2.3	1.6	2.0	1.1	1.5	1.6	-2.1	1.4	-1.7
Impedance of whole body	0.0	0.2	1.0	0.4	-1.0	-0.2	-0.3	-0.3	-0.2	-0.3	-0.2	-0.1	0.1	-0.8	-0.7	-0.1	-0.4	1.0	0.1	0.4
Leg fat mass (left)	0.3	1.4	9.4	-1.1	0.7	-1.1	-1.6	-0.6	-0.8	-0.5	-1.1	0.5	0.5	0.2	0.0	-0.3	-0.5	-3.1	-0.1	-2.2
Arm predicted mass (left)	2.1	10.5	21.3	3.0	4.1	3.0	-0.7	3.5	3.2	3.4	3.0	1.9	4.4	0.9	3.4	3.4	4.6	-4.5	3.3	-0.6