Best TWAS P=3.91e-08 · Best GWAS P=7.96e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | BCL2L11 | 0.04 | 0.04 | lasso | 2 | 0.03 | 0.0002 | 5.4 | -5.5 | 3.9e-08 | -1.00 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BCL2L11 | 0.04 | 0.02 | lasso | 3 | 0.02 | 0.0057 | 4.9 | -5.2 | 2.5e-07 | -0.61 | 0.04 | 0.40 | FALSE |