Best TWAS P=4.39e-11 · Best GWAS P=9.13e-10 conditioned to 0.361
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | REST | 0.05 | 0.01 | enet | 9 | 0.02 | 3.9e-03 | -4.3 | -5.1 | 2.9e-07 | 0.78 | 0.03 | 0.96 | FALSE |
| 2 | METSIM | Adipose | RP11-738E22.3 | 0.07 | 0.04 | lasso | 6 | 0.05 | 7.7e-08 | -6.1 | 6.5 | 7.5e-11 | -0.98 | 0.00 | 1.00 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | REST | 0.04 | 0.02 | bslmm | 536 | 0.02 | 3.4e-03 | -5.7 | -5.5 | 4.2e-08 | 0.58 | 0.06 | 0.86 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | REST | 0.04 | 0.01 | lasso | 5 | 0.02 | 7.8e-04 | -6.1 | -6.6 | 4.4e-11 | 0.86 | 0.01 | 0.96 | TRUE |