Best TWAS P=3.53e-09 · Best GWAS P=4.29e-13 conditioned to 2.09e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | MAPK9 | 0.13 | 0.06 | lasso | 5 | 0.05 | 1.7e-04 | 3.8 | 5.9 | 3.5e-09 | -0.86 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | MAPK9 | 0.07 | 0.00 | blup | 96 | 0.02 | 8.4e-04 | 2.8 | 5.8 | 7.2e-09 | -0.66 | 0.02 | 0.54 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | MAPK9 | 0.06 | 0.04 | lasso | 3 | 0.05 | 2.9e-05 | 6.2 | 5.8 | 5.6e-09 | -0.68 | 0.05 | 0.91 | FALSE |