Best TWAS P=3.72e-09 · Best GWAS P=2.23e-09 conditioned to 0.0515
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | DAGLB | 0.09 | 0.06 | lasso | 5 | 0.06 | 4.8e-08 | 6.0 | -5.9 | 3.7e-09 | -0.83 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RAC1 | 0.03 | 0.02 | enet | 7 | 0.02 | 6.8e-05 | 4.5 | 5.6 | 1.8e-08 | 0.69 | 0.14 | 0.73 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | DAGLB | 0.06 | 0.02 | blup | 71 | 0.03 | 7.4e-04 | 4.8 | -5.3 | 8.6e-08 | -0.70 | 0.01 | 0.78 | FALSE |