Best TWAS P=1.82e-09 · Best GWAS P=2.15e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | SNX13 | 0.19 | 0.16 | lasso | 2 | 0.13 | 1.5e-10 | 5.1 | 5.6 | 2.6e-08 | 0.64 | 0.59 | 0.41 | FALSE |
2 | GTEx | Nerve Tibial | SNX13 | 0.11 | 0.09 | lasso | 3 | 0.06 | 4.8e-05 | -5.7 | 5.8 | 8.8e-09 | 0.74 | 0.20 | 0.79 | FALSE |
3 | GTEx | Testis | SNX13 | 0.21 | 0.14 | enet | 15 | 0.13 | 2.0e-06 | -5.7 | 6.0 | 2.6e-09 | 0.80 | 0.15 | 0.85 | FALSE |
4 | METSIM | Adipose | SNX13 | 0.07 | 0.09 | lasso | 2 | 0.09 | 1.0e-13 | 5.1 | 5.6 | 1.7e-08 | 0.68 | 0.36 | 0.64 | FALSE |
5 | The Cancer Genome Atlas | Colon Adenocarcinoma | SNX13 | 0.15 | 0.16 | lasso | 3 | 0.18 | 1.7e-10 | 5.9 | -6.0 | 1.8e-09 | -0.96 | 0.02 | 0.98 | TRUE |