Best TWAS P=2.37e-12 · Best GWAS P=7.65e-12 conditioned to 0.368
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | PARP12 | 0.21 | 0.07 | lasso | 8 | 0.05 | 2.7e-03 | 5.4 | -5.2 | 2.6e-07 | -0.59 | 0.14 | 0.50 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | PARP12 | 0.02 | 0.01 | blup | 68 | 0.01 | 2.4e-02 | 6.6 | -6.7 | 1.6e-11 | -0.88 | 0.01 | 0.90 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PARP12 | 0.06 | 0.04 | lasso | 2 | 0.04 | 1.3e-04 | 6.5 | 6.2 | 5.9e-10 | 0.93 | 0.01 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | PARP12 | 0.14 | 0.11 | enet | 10 | 0.12 | 9.4e-12 | 6.8 | -7.0 | 2.4e-12 | -0.93 | 0.00 | 1.00 | TRUE |