Best TWAS P=6.98e-08 · Best GWAS P=6.92e-10 conditioned to 0.00237
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | SPAG8 | 0.11 | 0.10 | lasso | 7 | 0.06 | 2.0e-04 | 4.9 | -5.1 | 2.8e-07 | -0.86 | 0.02 | 0.97 | FALSE |
2 | GTEx | Thyroid | RP11-112J3.16 | 0.26 | 0.13 | lasso | 7 | 0.13 | 1.9e-10 | 4.8 | -5.4 | 7.0e-08 | -0.83 | 0.34 | 0.65 | TRUE |