Best TWAS P=5.07e-10 · Best GWAS P=5.13e-10 conditioned to 0.174
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | RALGPS1 | 0.05 | 0.01 | lasso | 6 | 0.02 | 2.7e-02 | -6.2 | -6.2 | 5.1e-10 | 0.91 | 0.03 | 0.92 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | RALGPS1 | 0.06 | 0.02 | lasso | 6 | 0.01 | 2.5e-02 | -6.2 | -5.6 | 1.7e-08 | 0.93 | 0.04 | 0.95 | FALSE |
| 3 | GTEx | Thyroid | RALGPS1 | 0.09 | 0.04 | enet | 12 | 0.01 | 2.7e-02 | -5.9 | 5.9 | 4.1e-09 | -0.78 | 0.03 | 0.96 | FALSE |
| 4 | METSIM | Adipose | RALGPS1 | 0.04 | 0.04 | lasso | 3 | 0.04 | 2.8e-06 | -5.5 | -5.7 | 9.5e-09 | 0.93 | 0.02 | 0.98 | FALSE |
| 5 | YFS | Blood | RALGPS1 | 0.08 | 0.13 | lasso | 18 | 0.15 | 1.1e-45 | -6.2 | -5.6 | 2.8e-08 | 0.93 | 0.02 | 0.98 | FALSE |