Best TWAS P=6.73e-11 · Best GWAS P=5.89e-08 conditioned to 0.000634
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | POMT1 | 0.31 | 0.05 | enet | 16 | 0.11 | 1.1e-03 | 5.1 | -5.4 | 7.3e-08 | 0.18 | 0.05 | 0.77 | FALSE |
| 2 | GTEx | Brain Cerebellum | POMT1 | 0.44 | 0.28 | lasso | 5 | 0.37 | 5.4e-12 | 5.0 | -5.1 | 3.0e-07 | 0.22 | 0.05 | 0.95 | FALSE |
| 3 | GTEx | Muscle Skeletal | UCK1 | 0.12 | 0.06 | enet | 6 | 0.06 | 8.0e-07 | 5.1 | 5.2 | 2.0e-07 | -0.15 | 0.05 | 0.94 | FALSE |
| 4 | GTEx | Muscle Skeletal | PRRC2B | 0.08 | 0.00 | enet | 11 | 0.00 | 9.8e-01 | 5.1 | -6.5 | 6.7e-11 | 0.34 | 0.06 | 0.42 | TRUE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | UCK1 | 0.06 | 0.03 | blup | 66 | 0.06 | 1.2e-04 | 4.1 | 5.2 | 1.8e-07 | -0.20 | 0.26 | 0.38 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | UCK1 | 0.03 | 0.03 | lasso | 3 | 0.04 | 1.3e-04 | 4.1 | 5.2 | 1.6e-07 | -0.09 | 0.27 | 0.41 | FALSE |