[Hub]/) : Traits : Trunk predicted mass :

chr9:138,525,778-140,321,666

Best TWAS P=2.57e-13 · Best GWAS P=3.36e-10 conditioned to 0.0143

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex INPP5E 0.18 0.14 enet 21 0.21 1.6e-24 6.0 -5.7 9.7e-09 -0.89 0.01 0.99 FALSE
2 GTEx Adrenal Gland INPP5E 0.18 0.02 enet 23 0.10 2.2e-04 4.7 -5.3 1.0e-07 -0.56 0.13 0.43 FALSE
3 GTEx Brain Caudate basal ganglia INPP5E 0.23 0.20 enet 8 0.22 7.2e-07 5.6 -5.5 3.5e-08 -0.62 0.18 0.71 FALSE
4 GTEx Brain Caudate basal ganglia SNHG7 0.37 0.10 lasso 6 0.27 2.5e-08 -3.9 7.3 2.6e-13 0.39 0.09 0.48 TRUE
5 GTEx Brain Cerebellar Hemisphere INPP5E 0.25 0.23 enet 6 0.17 3.4e-05 5.4 -5.8 8.1e-09 -0.68 0.18 0.75 FALSE
6 GTEx Brain Cerebellar Hemisphere GPSM1 0.26 0.07 lasso 4 0.11 9.6e-04 2.2 -5.1 2.8e-07 -0.70 0.02 0.88 FALSE
7 GTEx Brain Cerebellum INPP5E 0.40 0.30 enet 20 0.29 3.6e-09 5.6 -5.5 2.9e-08 -0.63 0.24 0.76 FALSE
8 GTEx Cells Transformed fibroblasts CARD9 0.10 0.01 enet 15 0.02 8.0e-03 -1.0 -5.3 1.5e-07 -0.47 0.16 0.55 FALSE
9 GTEx Esophagus Mucosa INPP5E 0.11 0.12 lasso 3 0.12 1.0e-08 5.4 -5.4 5.5e-08 -0.67 0.27 0.73 FALSE
10 GTEx Esophagus Muscularis SDCCAG3 0.10 0.02 enet 5 0.02 3.6e-02 3.4 -5.5 3.8e-08 -0.59 0.04 0.86 FALSE
11 GTEx Heart Atrial Appendage INPP5E 0.13 0.12 lasso 2 0.10 3.5e-05 5.6 -5.6 2.6e-08 -0.71 0.11 0.67 FALSE
12 GTEx Lung CARD9 0.08 0.04 enet 6 0.04 2.5e-04 5.3 5.4 7.7e-08 0.59 0.46 0.48 FALSE
13 GTEx Nerve Tibial INPP5E 0.13 0.17 enet 10 0.14 3.7e-10 5.4 -5.7 1.2e-08 -0.64 0.34 0.66 FALSE
14 GTEx Ovary INPP5E 0.24 0.13 enet 11 0.15 1.9e-04 5.2 -6.5 8.1e-11 -0.59 0.08 0.52 FALSE
15 GTEx Ovary SEC16A 0.33 0.06 enet 10 0.14 3.4e-04 4.7 -6.5 8.9e-11 -0.45 0.06 0.10 TRUE
16 GTEx Skin Sun Exposed Lower leg INPP5E 0.10 0.10 lasso 2 0.09 5.2e-08 5.4 -5.2 1.8e-07 -0.66 0.24 0.76 FALSE
17 GTEx Stomach SEC16A 0.15 0.09 lasso 4 0.10 1.8e-05 5.7 -5.6 2.4e-08 -0.69 0.10 0.88 FALSE
18 GTEx Testis SDCCAG3 0.15 0.09 lasso 4 0.13 3.3e-06 4.3 -5.4 6.6e-08 -0.84 0.07 0.91 FALSE
19 GTEx Thyroid INPP5E 0.23 0.35 enet 16 0.37 8.2e-30 4.7 -5.4 8.3e-08 -0.74 0.81 0.19 FALSE
20 GTEx Uterus INPP5E 0.60 0.04 enet 10 0.22 3.4e-05 5.9 -5.7 1.6e-08 -0.53 0.07 0.39 FALSE
21 GTEx Whole Blood SEC16A 0.07 0.05 lasso 5 0.04 1.3e-04 5.6 -6.2 7.9e-10 -0.72 0.06 0.94 FALSE
22 GTEx Whole Blood SDCCAG3 0.07 0.03 enet 6 0.02 3.4e-03 4.9 -5.4 8.2e-08 -0.79 0.13 0.81 FALSE
23 GTEx Whole Blood CARD9 0.08 0.07 lasso 1 0.05 4.2e-05 5.4 5.4 7.4e-08 0.55 0.36 0.63 FALSE
24 YFS Blood CARD9 0.22 0.37 lasso 5 0.39 1.3e-137 5.4 5.3 1.2e-07 0.64 0.39 0.61 FALSE
25 YFS Blood INPP5E 0.33 0.55 lasso 6 0.57 2.9e-235 5.9 -5.9 4.3e-09 -0.70 0.05 0.95 FALSE
26 The Cancer Genome Atlas Breast Invasive Carcinoma SEC16A 0.02 0.00 blup 69 0.01 1.0e-03 5.6 -5.2 1.8e-07 -0.75 0.02 0.89 FALSE
27 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma INPP5E 0.25 0.10 lasso 3 0.09 4.9e-05 5.9 -6.2 7.8e-10 -0.73 0.03 0.93 FALSE
28 The Cancer Genome Atlas Colon Adenocarcinoma INPP5E 0.11 0.08 lasso 2 0.08 3.4e-05 5.9 -5.9 2.9e-09 -0.72 0.02 0.88 FALSE
29 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma INPP5E 0.07 0.04 blup 54 0.07 6.0e-05 6.3 -6.3 2.1e-10 -0.84 0.01 0.97 FALSE
30 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SDCCAG3 0.05 0.01 blup 61 0.01 5.9e-02 6.0 -5.6 2.7e-08 -0.81 0.01 0.88 FALSE
31 The Cancer Genome Atlas Prostate Adenocarcinoma SEC16A 0.08 0.10 lasso 4 0.08 1.9e-08 6.2 -6.0 1.5e-09 -0.98 0.00 1.00 FALSE
32 The Cancer Genome Atlas Testicular Germ Cell Tumors INPP5E 0.10 0.06 blup 54 0.08 8.1e-04 5.4 -5.9 3.8e-09 -0.82 0.05 0.61 FALSE
33 The Cancer Genome Atlas Thyroid Carcinoma INPP5E 0.11 0.16 lasso 3 0.16 2.4e-15 5.2 -5.5 5.1e-08 -0.70 0.63 0.37 FALSE