[Hub]/) : Traits : Trunk predicted mass : ← →

chr10:4,236,655-5,844,628

Best TWAS P=5.25e-14 · Best GWAS P=8.52e-14 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Cells Transformed fibroblasts	AKR1C2	0.28	0.23	lasso	6	0.21	1.9e-15	-7.5	-7.5	5.2e-14	1.00	0.00	1.00	TRUE
7	GTEx	Esophagus Muscularis	AKR1C2	0.30	0.21	lasso	2	0.19	8.5e-12	-7.5	-7.5	6.3e-14	1.00	0.00	1.00	FALSE
10	GTEx	Skin Sun Exposed Lower leg	AKR1C2	0.17	0.18	lasso	2	0.18	4.0e-15	-7.4	-7.4	9.7e-14	1.00	0.00	1.00	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AKR1C2	0.12	0.11	lasso	6	0.09	1.6e-10	-7.5	-7.4	1.2e-13	1.00	0.00	1.00	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	AKR1C2	0.56	0.40	enet	28	0.46	1.0e-65	-7.5	-7.3	2.4e-13	0.93	0.00	1.00	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AKR1C1	0.07	0.04	enet	10	0.02	1.0e-03	-7.2	7.3	2.7e-13	-0.88	0.00	0.99	FALSE
8	GTEx	Heart Atrial Appendage	AKR1C2	0.28	0.37	lasso	3	0.29	1.2e-13	-7.3	-7.3	3.6e-13	0.98	0.00	1.00	FALSE
15	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	AKR1C2	0.29	0.21	lasso	1	0.21	4.7e-12	-7.3	-7.3	3.7e-13	0.98	0.00	1.00	FALSE
11	GTEx	Testis	AKR1C2	0.44	0.36	lasso	4	0.36	8.5e-17	-7.5	-7.2	5.7e-13	1.00	0.00	1.00	FALSE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	AKR1C2	0.39	0.18	enet	14	0.23	2.5e-23	-7.5	-6.8	8.4e-12	0.85	0.00	1.00	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	AKR1C2	0.09	0.08	lasso	3	0.08	7.2e-08	-7.2	-6.8	1.3e-11	0.90	0.00	1.00	FALSE
3	GTEx	Artery Tibial	AKR1C2	0.14	0.10	enet	10	0.15	1.2e-11	-7.3	-6.4	1.2e-10	0.94	0.00	1.00	FALSE
9	GTEx	Ovary	AKR1C3	0.35	0.20	lasso	9	0.22	3.9e-06	-7.5	-6.4	1.9e-10	0.91	0.01	0.97	FALSE
4	GTEx	Brain Cerebellar Hemisphere	AKR1C1	0.46	0.14	lasso	4	0.23	1.4e-06	-3.5	6.3	2.2e-10	-0.85	0.01	0.96	FALSE
5	GTEx	Brain Cortex	AKR1C2	0.49	0.10	lasso	11	0.26	1.1e-07	-7.5	-6.2	7.8e-10	0.85	0.01	0.98	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	AKR1C2	0.09	0.05	blup	62	0.05	3.4e-06	-7.2	-5.8	5.4e-09	0.89	0.00	1.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	AKR1C1	0.30	0.16	bslmm	703	0.18	3.5e-21	2.6	5.2	1.6e-07	-0.55	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	AKR1C2	0.31	0.06	bslmm	665	0.16	2.1e-19	0.8	-5.1	2.8e-07	0.74	0.10	0.90	FALSE
18	The Cancer Genome Atlas	Soft Tissue Sarcoma	AKR1C2	0.07	0.04	enet	5	0.06	1.1e-04	-3.5	-5.1	2.8e-07	0.74	0.02	0.80	FALSE