Best TWAS P=7.7e-09 · Best GWAS P=5.88e-09 conditioned to 0.143
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PIP4K2A | 0.20 | 0.18 | lasso | 1 | 0.18 | 6.4e-21 | 5.8 | -5.8 | 7.7e-09 | -0.90 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Artery Tibial | PIP4K2A | 0.06 | 0.01 | enet | 8 | 0.02 | 2.1e-02 | 5.4 | -5.2 | 2.7e-07 | -0.64 | 0.08 | 0.66 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | PIP4K2A | 0.24 | 0.20 | lasso | 2 | 0.19 | 2.9e-14 | 5.4 | -5.3 | 1.4e-07 | -0.78 | 0.05 | 0.95 | FALSE |