[Hub]/) : Traits : Trunk predicted mass :

chr12:27,587,038-30,170,382

Best TWAS P=6.9e-17 · Best GWAS P=7.75e-17 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC91 0.08 0.06 lasso 6 0.07 9.4e-09 -7.6 6.8 1.4e-11 -0.87 0.31 0.69 FALSE
2 GTEx Adrenal Gland CCDC91 0.16 0.01 lasso 16 0.03 3.5e-02 3.4 -5.4 5.2e-08 0.40 0.08 0.54 FALSE
3 GTEx Adrenal Gland RP11-996F15.2 0.62 0.55 lasso 7 0.55 3.0e-23 5.3 5.3 1.0e-07 0.05 0.00 1.00 FALSE
4 GTEx Artery Aorta RP11-967K21.1 0.07 0.02 lasso 7 0.01 7.9e-02 5.0 7.4 1.6e-13 -0.83 0.08 0.78 FALSE
5 GTEx Artery Aorta RP11-996F15.2 0.35 0.28 lasso 4 0.28 1.5e-15 5.3 5.2 2.0e-07 0.05 0.00 1.00 FALSE
6 GTEx Artery Tibial RP11-996F15.2 0.44 0.40 enet 28 0.44 1.2e-37 5.4 5.5 4.5e-08 0.07 0.00 1.00 FALSE
7 GTEx Brain Cerebellum RP11-996F15.2 0.25 0.15 lasso 4 0.10 7.6e-04 5.3 5.2 2.0e-07 0.05 0.01 0.93 FALSE
8 GTEx Breast Mammary Tissue RP11-996F15.2 0.45 0.35 lasso 8 0.31 1.2e-16 5.4 5.4 8.4e-08 0.05 0.00 1.00 FALSE
9 GTEx Breast Mammary Tissue (Male) RP11-996F15.2 0.52 0.28 lasso 9 0.23 4.1e-06 5.3 5.4 5.5e-08 0.06 0.01 0.98 FALSE
10 GTEx Breast Mammary Tissue (Female) RP11-996F15.2 0.42 0.38 lasso 1 0.35 3.5e-11 5.3 5.3 1.4e-07 0.05 0.00 1.00 FALSE
11 GTEx Cells EBV-transformed lymphocytes RP11-996F15.2 0.27 0.24 lasso 4 0.23 6.0e-08 5.3 5.1 2.8e-07 0.05 0.00 0.99 FALSE
12 GTEx Cells Transformed fibroblasts CCDC91 0.10 0.10 lasso 5 0.09 5.5e-07 -7.8 -7.9 2.0e-15 0.85 0.16 0.84 FALSE
13 GTEx Cells Transformed fibroblasts RP11-967K21.1 0.07 0.07 lasso 2 0.07 3.7e-06 -8.2 8.3 6.9e-17 -0.96 0.03 0.97 TRUE
14 GTEx Colon Sigmoid RP11-996F15.2 0.42 0.27 lasso 7 0.29 7.7e-11 5.3 5.1 3.0e-07 0.06 0.00 1.00 FALSE
15 GTEx Colon Transverse CCDC91 0.11 0.01 lasso 6 0.00 4.6e-01 -7.7 -7.4 1.8e-13 0.80 0.09 0.74 FALSE
16 GTEx Colon Transverse RP11-996F15.2 0.31 0.32 lasso 1 0.31 3.5e-15 5.3 5.3 1.4e-07 0.05 0.00 1.00 FALSE
17 GTEx Esophagus Mucosa CCDC91 0.18 0.04 enet 36 0.03 3.1e-03 5.0 -5.7 1.5e-08 0.53 0.15 0.66 FALSE
18 GTEx Esophagus Mucosa RP11-996F15.2 0.39 0.43 lasso 7 0.45 6.2e-33 5.3 5.2 1.8e-07 0.06 0.00 1.00 FALSE
19 GTEx Esophagus Muscularis RP11-996F15.2 0.56 0.45 enet 31 0.47 1.3e-31 5.3 5.2 1.8e-07 0.04 0.00 1.00 FALSE
20 GTEx Heart Atrial Appendage CCDC91 0.10 0.06 lasso 8 0.04 4.4e-03 -7.8 -7.2 5.6e-13 0.85 0.05 0.90 FALSE
21 GTEx Heart Atrial Appendage RP11-967K21.1 0.08 0.09 lasso 1 0.08 2.3e-04 -8.2 8.2 3.0e-16 -0.91 0.03 0.94 FALSE
22 GTEx Lung RP11-996F15.2 0.50 0.46 lasso 5 0.46 1.9e-39 5.3 5.1 3.0e-07 0.05 0.00 1.00 FALSE
23 GTEx Muscle Skeletal RP11-967K21.1 0.04 0.01 lasso 9 0.00 2.9e-01 -7.7 7.3 3.6e-13 -0.90 0.07 0.77 FALSE
24 GTEx Muscle Skeletal RP11-996F15.2 0.24 0.26 lasso 11 0.25 9.3e-25 5.4 5.3 1.4e-07 0.06 0.00 1.00 FALSE
25 GTEx Pancreas RP11-996F15.2 0.56 0.46 enet 22 0.48 1.8e-22 5.3 5.2 2.0e-07 0.04 0.00 1.00 FALSE
26 GTEx Pituitary RP11-967K21.1 0.20 0.04 lasso 7 0.04 4.4e-02 3.1 5.7 1.5e-08 -0.62 0.07 0.47 FALSE
27 GTEx Prostate RP11-996F15.2 0.49 0.36 enet 32 0.39 6.0e-11 5.3 5.4 5.2e-08 0.04 0.00 1.00 FALSE
28 GTEx Skin Not Sun Exposed Suprapubic CCDC91 0.26 0.05 lasso 15 0.04 4.1e-03 -8.3 -7.5 5.3e-14 0.87 0.04 0.95 FALSE
29 GTEx Skin Not Sun Exposed Suprapubic RP11-996F15.2 0.44 0.28 enet 55 0.28 1.1e-15 5.3 5.1 3.1e-07 0.05 0.00 1.00 FALSE
30 GTEx Skin Sun Exposed Lower leg CCDC91 0.09 0.01 enet 8 0.01 2.6e-02 -8.2 -8.3 1.5e-16 0.85 0.05 0.91 FALSE
31 GTEx Skin Sun Exposed Lower leg RP11-996F15.2 0.50 0.48 enet 21 0.50 1.5e-47 5.4 5.2 1.7e-07 0.05 0.00 1.00 FALSE
32 GTEx Small Intestine Terminal Ileum RP11-996F15.2 0.60 0.51 lasso 5 0.46 7.1e-12 5.4 5.5 4.4e-08 0.05 0.00 1.00 TRUE
33 GTEx Stomach RP11-996F15.2 0.35 0.41 lasso 3 0.40 1.4e-20 5.3 5.2 2.3e-07 0.04 0.00 1.00 FALSE
34 GTEx Thyroid CCDC91 0.15 0.12 enet 42 0.12 2.9e-09 -7.9 -6.0 1.8e-09 0.81 0.07 0.93 FALSE
35 GTEx Thyroid RP11-996F15.2 0.54 0.54 lasso 8 0.55 9.1e-50 5.4 5.2 2.1e-07 0.05 0.00 1.00 FALSE
36 NTR Blood CCDC91 0.01 0.01 blup 648 0.00 9.0e-03 3.3 -5.7 1.0e-08 0.75 0.26 0.40 FALSE
37 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC91 0.04 0.04 lasso 3 0.03 1.8e-06 -7.6 -7.6 2.1e-14 0.94 0.19 0.81 FALSE
38 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC91 0.06 0.02 blup 174 0.04 2.9e-05 4.0 -6.9 4.2e-12 0.79 0.39 0.59 FALSE
39 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ERGIC2 0.04 0.03 lasso 2 0.03 1.3e-04 5.3 -5.2 2.1e-07 -0.04 0.01 0.99 FALSE
40 The Cancer Genome Atlas Lung Adenocarcinoma CCDC91 0.09 0.01 blup 170 0.02 1.0e-03 -7.9 -6.4 1.7e-10 0.75 0.16 0.71 FALSE
41 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CCDC91 0.09 0.11 lasso 2 0.12 2.3e-05 -7.8 -7.8 6.3e-15 0.91 0.08 0.90 FALSE
42 The Cancer Genome Atlas Thyroid Carcinoma CCDC91 0.40 0.12 blup 175 0.14 4.9e-13 -7.9 -7.3 2.6e-13 0.72 0.08 0.92 FALSE