Best TWAS P=4.38e-09 · Best GWAS P=1.25e-07 conditioned to 0.00442
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | AL137059.1 | 0.10 | 0.02 | lasso | 3 | 0.03 | 0.0029 | 4.7 | -5.2 | 1.8e-07 | -0.63 | 0.05 | 0.82 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GTF3A | 0.03 | 0.00 | enet | 8 | 0.01 | 0.0228 | 2.7 | 5.9 | 4.4e-09 | 0.47 | 0.02 | 0.48 | TRUE |