Best TWAS P=1.24e-08 · Best GWAS P=1.27e-07 conditioned to 0.108
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2 | GTEx | Colon Sigmoid | DCAF4 | 0.30 | 0.10 | lasso | 9 | 0.11 | 1.3e-04 | 5.0 | 5.7 | 1.2e-08 | 0.74 | 0.01 | 0.91 | TRUE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | DCAF4 | 0.18 | 0.01 | enet | 10 | 0.06 | 3.0e-03 | 5.0 | 5.6 | 1.7e-08 | 0.53 | 0.03 | 0.74 | FALSE |
| 1 | GTEx | Adipose Visceral Omentum | DCAF4 | 0.23 | 0.07 | enet | 30 | 0.13 | 4.3e-07 | 4.5 | 5.5 | 4.9e-08 | 0.48 | 0.03 | 0.95 | FALSE |
| 4 | GTEx | Esophagus Mucosa | ZFYVE1 | 0.10 | 0.00 | lasso | 7 | 0.00 | 2.0e-01 | 5.0 | 5.4 | 6.1e-08 | 0.61 | 0.06 | 0.76 | FALSE |
| 5 | GTEx | Spleen | DCAF4 | 0.47 | 0.12 | enet | 10 | 0.19 | 1.5e-05 | 4.2 | 5.4 | 7.2e-08 | 0.63 | 0.07 | 0.87 | FALSE |
| 6 | NTR | Blood | DCAF4 | 0.04 | 0.03 | lasso | 6 | 0.03 | 6.5e-09 | 5.0 | 5.2 | 1.9e-07 | 0.60 | 0.01 | 0.99 | FALSE |