[Hub]/) : Traits : Trunk predicted mass :

chr19:1,127,720-5,153,606

Best TWAS P=4.91e-20 · Best GWAS P=2.2e-20 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex REXO1 0.07 0.01 bslmm 391 0.01 1.7e-02 -1.22 5.5 3.7e-08 -0.20 0.28 0.03 TRUE
2 CommonMind Brain Pre-frontal Cortex UBXN6 0.27 0.25 enet 28 0.29 4.6e-36 4.82 -6.1 1.4e-09 -0.05 0.09 0.91 FALSE
3 GTEx Adipose Subcutaneous AMH 0.18 0.05 lasso 8 0.06 1.9e-05 -3.47 5.2 1.6e-07 -0.22 0.92 0.01 FALSE
4 GTEx Adipose Visceral Omentum NFIC 0.20 0.00 lasso 5 0.02 2.2e-02 5.39 -5.3 1.1e-07 0.07 0.07 0.14 FALSE
5 GTEx Adipose Visceral Omentum CHAF1A 0.24 0.26 lasso 3 0.26 6.2e-14 5.37 -5.3 1.2e-07 -0.04 0.01 0.99 FALSE
6 GTEx Adrenal Gland CHAF1A 0.22 0.18 lasso 3 0.17 1.1e-06 4.81 -5.1 2.9e-07 -0.04 0.02 0.97 FALSE
7 GTEx Artery Aorta UBXN6 0.13 0.02 lasso 5 0.03 5.7e-03 -4.72 -6.0 1.4e-09 -0.03 0.06 0.88 FALSE
8 GTEx Artery Aorta CTB-50L17.5 0.16 0.15 lasso 7 0.15 1.0e-08 5.59 -5.5 4.9e-08 -0.03 0.02 0.98 FALSE
9 GTEx Artery Coronary CTB-50L17.9 0.43 0.14 lasso 6 0.12 6.5e-05 4.91 -5.2 2.3e-07 -0.01 0.12 0.48 FALSE
10 GTEx Artery Tibial DOT1L 0.09 0.06 lasso 5 0.05 7.3e-05 8.78 8.3 1.5e-16 -0.89 0.03 0.97 TRUE
11 GTEx Artery Tibial NFIC 0.14 0.13 enet 11 0.12 7.6e-10 5.39 -5.6 2.6e-08 0.02 0.86 0.14 TRUE
12 GTEx Artery Tibial UBXN6 0.18 0.07 lasso 3 0.14 6.3e-11 5.83 -6.2 4.1e-10 -0.05 0.01 0.99 FALSE
13 GTEx Artery Tibial AC005306.3 0.25 0.12 enet 59 0.11 3.9e-09 -2.35 -5.2 1.7e-07 0.16 1.00 0.00 TRUE
14 GTEx Brain Caudate basal ganglia CTB-50L17.9 0.27 0.25 lasso 2 0.24 1.8e-07 5.59 -5.6 1.9e-08 -0.03 0.03 0.92 FALSE
15 GTEx Brain Cerebellar Hemisphere CHAF1A 0.62 0.40 lasso 8 0.36 3.5e-10 5.59 -5.5 3.0e-08 -0.04 0.02 0.98 FALSE
16 GTEx Brain Cerebellum CHAF1A 0.51 0.35 lasso 4 0.34 9.7e-11 5.59 -5.5 3.6e-08 -0.03 0.02 0.98 FALSE
17 GTEx Brain Cerebellum CTB-50L17.9 0.53 0.41 lasso 2 0.50 3.6e-17 4.91 -5.5 4.0e-08 -0.04 0.06 0.94 FALSE
18 GTEx Brain Frontal Cortex BA9 UBXN6 0.31 0.06 enet 5 0.12 3.5e-04 4.91 -5.3 1.2e-07 -0.05 0.04 0.79 FALSE
19 GTEx Brain Frontal Cortex BA9 CTB-50L17.9 0.27 0.21 lasso 3 0.19 7.9e-06 4.91 -5.4 6.4e-08 -0.04 0.07 0.87 FALSE
20 GTEx Brain Frontal Cortex BA9 AC007292.6 0.35 0.01 lasso 6 0.12 3.6e-04 -0.16 -5.4 7.7e-08 0.02 0.02 0.69 FALSE
21 GTEx Brain Nucleus accumbens basal ganglia CHAF1A 0.31 0.28 lasso 2 0.24 4.0e-07 5.37 -5.4 8.2e-08 -0.03 0.02 0.97 FALSE
22 GTEx Brain Nucleus accumbens basal ganglia CTB-50L17.9 0.45 0.25 lasso 8 0.23 8.6e-07 5.59 -6.2 6.1e-10 -0.02 0.06 0.91 FALSE
23 GTEx Breast Mammary Tissue (Female) CHAF1A 0.33 0.14 lasso 6 0.09 1.6e-03 5.37 -5.2 2.2e-07 -0.04 0.03 0.91 FALSE
24 GTEx Colon Sigmoid CHAF1A 0.33 0.08 lasso 5 0.12 7.5e-05 5.37 -5.2 2.3e-07 -0.03 0.02 0.96 FALSE
25 GTEx Colon Sigmoid UBXN6 0.34 0.15 lasso 6 0.14 1.7e-05 4.91 -5.7 1.2e-08 -0.03 0.08 0.89 FALSE
26 GTEx Esophagus Muscularis UBXN6 0.35 0.24 enet 20 0.29 3.7e-18 4.91 -5.5 3.3e-08 -0.03 0.04 0.96 FALSE
27 GTEx Heart Atrial Appendage UBXN6 0.34 0.12 lasso 6 0.21 6.5e-10 5.59 -5.8 5.1e-09 -0.03 0.08 0.92 FALSE
28 GTEx Heart Left Ventricle CHAF1A 0.17 0.12 lasso 2 0.11 1.9e-06 5.59 -5.6 2.0e-08 -0.04 0.01 0.99 FALSE
29 GTEx Heart Left Ventricle UBXN6 0.21 0.14 lasso 6 0.16 5.6e-09 -4.79 -5.6 1.9e-08 -0.03 0.44 0.55 FALSE
30 GTEx Lung CTB-50L17.5 0.24 0.05 enet 43 0.10 2.2e-08 5.59 -5.1 3.0e-07 -0.04 0.02 0.98 FALSE
31 GTEx Muscle Skeletal CHAF1A 0.18 0.21 lasso 2 0.20 9.7e-20 5.59 -5.6 2.5e-08 -0.03 0.02 0.98 FALSE
32 GTEx Muscle Skeletal UBXN6 0.19 0.14 lasso 5 0.18 4.1e-17 -4.81 -6.1 9.9e-10 -0.02 0.55 0.45 FALSE
33 GTEx Nerve Tibial UBXN6 0.17 0.08 enet 20 0.09 4.4e-07 5.09 -5.5 4.4e-08 -0.07 0.05 0.95 FALSE
34 GTEx Nerve Tibial CTB-50L17.5 0.11 0.08 enet 4 0.08 1.6e-06 5.37 -5.5 4.7e-08 -0.04 0.02 0.98 FALSE
35 GTEx Prostate UBXN6 0.27 0.15 enet 19 0.14 2.4e-04 4.91 -5.5 4.8e-08 -0.04 0.08 0.38 FALSE
36 GTEx Skin Not Sun Exposed Suprapubic AC007292.6 0.11 0.08 lasso 6 0.07 7.8e-05 5.83 -5.5 3.8e-08 -0.05 0.01 0.98 FALSE
37 GTEx Skin Sun Exposed Lower leg CHAF1A 0.19 0.18 lasso 1 0.17 5.1e-14 5.37 -5.4 7.7e-08 -0.03 0.03 0.97 FALSE
38 GTEx Stomach AC007292.4 0.27 0.09 lasso 5 0.04 4.0e-03 -5.14 5.3 1.2e-07 0.03 0.06 0.64 FALSE
39 GTEx Testis CHAF1A 0.18 0.09 lasso 2 0.07 4.0e-04 5.59 -5.3 8.9e-08 -0.03 0.02 0.88 FALSE
40 GTEx Testis CTB-50L17.9 0.39 0.30 enet 36 0.34 9.4e-16 4.91 -6.0 2.7e-09 -0.06 0.16 0.84 FALSE
41 GTEx Thyroid UBXN6 0.25 0.19 lasso 5 0.23 8.8e-18 5.83 -5.6 1.9e-08 -0.05 0.02 0.98 FALSE
42 GTEx Vagina CTB-50L17.9 0.38 0.26 lasso 5 0.23 5.7e-06 5.59 -5.6 2.0e-08 -0.05 0.04 0.89 FALSE
43 NTR Blood C19orf35 0.03 0.01 enet 9 0.02 3.7e-07 -2.74 -6.1 9.3e-10 0.38 0.96 0.03 FALSE
44 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma UBXN6 0.05 0.01 blup 57 0.04 6.6e-05 5.59 -7.0 2.2e-12 -0.04 0.01 0.98 TRUE
45 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CHAF1A 0.12 0.11 lasso 3 0.12 7.9e-13 5.37 -5.7 1.4e-08 -0.05 0.01 0.99 FALSE
46 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DOT1L 0.08 0.12 enet 8 0.10 2.5e-11 8.78 9.2 4.9e-20 -0.96 0.01 0.99 TRUE
47 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MPND 0.05 0.03 lasso 3 0.02 5.3e-03 5.23 5.2 2.6e-07 0.03 0.03 0.67 FALSE
48 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma UBXN6 0.18 0.17 enet 18 0.18 9.9e-20 5.59 -5.4 6.3e-08 -0.03 0.00 1.00 FALSE
49 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CHAF1A 0.15 0.12 lasso 2 0.12 3.2e-07 5.37 -5.4 7.0e-08 -0.04 0.02 0.98 FALSE
50 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma JSRP1 0.07 0.04 blup 33 0.03 7.8e-03 -3.90 5.8 7.4e-09 -0.43 0.01 0.14 FALSE
51 The Cancer Genome Atlas Liver Hepatocellular Carcinoma DOT1L 0.09 0.08 blup 60 0.07 4.1e-04 -7.35 8.3 7.9e-17 -0.87 0.03 0.94 TRUE
52 The Cancer Genome Atlas Lung Adenocarcinoma CHAF1A 0.05 0.04 lasso 4 0.03 2.3e-04 5.59 -5.3 1.1e-07 -0.03 0.01 0.98 FALSE
53 The Cancer Genome Atlas Lung Squamous Cell Carcinoma JSRP1 0.03 0.00 blup 33 0.02 2.1e-03 -3.10 -6.1 1.3e-09 0.18 0.01 0.18 TRUE
54 The Cancer Genome Atlas Lung Squamous Cell Carcinoma UBXN6 0.04 0.03 lasso 2 0.02 1.6e-03 4.91 -5.4 7.5e-08 -0.03 0.00 0.91 FALSE
55 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CHAF1A 0.20 0.11 lasso 2 0.11 5.6e-05 5.83 -5.9 3.2e-09 -0.05 0.00 0.99 FALSE
56 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma UBXN6 0.23 0.11 lasso 5 0.12 2.5e-05 4.91 -5.9 3.0e-09 -0.06 0.02 0.75 FALSE
57 The Cancer Genome Atlas Prostate Adenocarcinoma UBXN6 0.13 0.10 lasso 2 0.10 1.3e-10 5.59 -5.9 3.3e-09 -0.04 0.00 1.00 FALSE
58 The Cancer Genome Atlas Testicular Germ Cell Tumors DOT1L 0.40 -0.01 enet 20 0.03 3.6e-02 -3.66 6.2 7.9e-10 -0.44 0.01 0.20 FALSE
59 The Cancer Genome Atlas Thyroid Carcinoma UBXN6 0.16 0.12 lasso 2 0.12 5.4e-12 5.59 -5.8 8.1e-09 -0.04 0.00 1.00 FALSE