Best TWAS P=8.34e-09 · Best GWAS P=4.08e-09 conditioned to 0.175
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | AC062029.1 | 0.14 | 0.10 | enet | 11 | 0.12 | 1.3e-09 | 4.8 | 5.8 | 8.3e-09 | 0.94 | 0 | 1 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | AC062029.1 | 0.07 | 0.08 | lasso | 3 | 0.07 | 3.0e-06 | 5.9 | 5.5 | 3.3e-08 | 0.98 | 0 | 1 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | EIF2AK3 | 0.11 | 0.09 | lasso | 5 | 0.09 | 2.0e-11 | 5.9 | 5.2 | 2.1e-07 | 0.97 | 0 | 1 | FALSE |