Best TWAS P=1.04e-08 · Best GWAS P=7.51e-09 conditioned to 0.208
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | BIN1 | 0.15 | 0.14 | lasso | 5 | 0.12 | 9.3e-07 | 5.6 | -5.5 | 4.4e-08 | -0.93 | 0 | 1 | FALSE |
| 2 | GTEx | Pancreas | BIN1 | 0.34 | 0.25 | lasso | 4 | 0.24 | 1.5e-10 | 5.7 | -5.7 | 1.0e-08 | -0.93 | 0 | 1 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | BIN1 | 0.16 | 0.09 | blup | 96 | 0.12 | 2.1e-11 | 5.8 | -5.3 | 1.2e-07 | -0.70 | 0 | 1 | FALSE |