Best TWAS P=1.46e-11 · Best GWAS P=6.49e-10 conditioned to 0.0366
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | DCBLD2 | 0.16 | 0.13 | lasso | 3 | 0.14 | 2.4e-11 | -5.6 | 5.2 | 2.2e-07 | 0.13 | 0.05 | 0.95 | FALSE |
| 2 | GTEx | Nerve Tibial | DCBLD2 | 0.14 | 0.05 | lasso | 5 | 0.03 | 1.7e-03 | 4.7 | 5.6 | 1.9e-08 | 0.63 | 0.15 | 0.48 | FALSE |
| 3 | GTEx | Thyroid | DCBLD2 | 0.14 | 0.12 | lasso | 5 | 0.15 | 1.5e-11 | -5.6 | 6.1 | 1.1e-09 | 0.28 | 0.04 | 0.96 | FALSE |
| 4 | METSIM | Adipose | CPOX | 0.09 | 0.02 | blup | 456 | 0.05 | 6.4e-08 | -1.1 | -5.3 | 1.2e-07 | -0.40 | 0.66 | 0.33 | FALSE |
| 5 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | DCBLD2 | 0.07 | 0.06 | enet | 3 | 0.07 | 7.6e-04 | -5.2 | 5.3 | 9.4e-08 | 0.15 | 0.05 | 0.64 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DCBLD2 | 0.09 | 0.01 | enet | 16 | 0.04 | 9.6e-05 | 4.9 | 6.8 | 1.5e-11 | 0.69 | 0.04 | 0.80 | TRUE |