Best TWAS P=1.23e-08 · Best GWAS P=9.69e-06 conditioned to 0.548
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | SLC51A | 0.28 | 0.06 | lasso | 6 | 0.14 | 1.3e-07 | 3.8 | -5.7 | 1.2e-08 | 0.70 | 0.01 | 0.78 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | SLC51A | 0.30 | 0.22 | lasso | 4 | 0.24 | 5.0e-18 | 3.8 | -5.3 | 1.4e-07 | 0.45 | 0.05 | 0.58 | FALSE |
| 3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | PCYT1A | 0.12 | 0.05 | blup | 68 | 0.06 | 2.0e-04 | 4.3 | -5.4 | 8.2e-08 | 0.40 | 0.01 | 0.51 | FALSE |