Best TWAS P=4.56e-08 · Best GWAS P=1.93e-06 conditioned to 0.268
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue (Male) | SPIRE2 | 0.27 | -0.01 | enet | 29 | 0.04 | 3.4e-02 | 2.5 | -5.5 | 4.6e-08 | -0.39 | 0 | 0.02 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | DPEP1 | 0.05 | 0.01 | enet | 7 | 0.02 | 5.2e-05 | 4.8 | 5.2 | 2.0e-07 | 0.76 | 0 | 0.92 | TRUE |