Best TWAS P=2.71e-10 · Best GWAS P=1.23e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | C11orf63 | 0.12 | 0.11 | lasso | 5 | 0.10 | 2.3e-08 | 5.6 | -5.2 | 2.0e-07 | 0.79 | 0.48 | 0.52 | FALSE |
2 | GTEx | Nerve Tibial | C11orf63 | 0.24 | 0.08 | enet | 18 | 0.22 | 6.2e-16 | 3.1 | -5.9 | 3.9e-09 | 0.57 | 0.42 | 0.58 | TRUE |
3 | GTEx | Testis | C11orf63 | 0.32 | 0.14 | lasso | 7 | 0.08 | 3.2e-04 | -5.7 | 6.3 | 2.7e-10 | -0.97 | 0.01 | 0.99 | TRUE |