Best TWAS P=8.97e-10 · Best GWAS P=5.45e-11 conditioned to 0.0189
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | 6.2 | 6.1 | 1e-09 | 0.90 | 0.05 | 0.95 | FALSE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | 6.2 | 6.1 | 9e-10 | 0.92 | 0.06 | 0.94 | TRUE |