Best TWAS P=4.22e-08 · Best GWAS P=3.91e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | RP5-1042I8.7 | 0.17 | 0.00 | lasso | 11 | 0.03 | 0.01400 | 5.5 | 5.4 | 7.8e-08 | 0.99 | 0.02 | 0.98 | FALSE |
2 | GTEx | Artery Coronary | RP5-1042I8.7 | 0.11 | 0.07 | lasso | 2 | 0.04 | 0.01750 | 5.2 | 5.1 | 2.8e-07 | 0.98 | 0.02 | 0.90 | FALSE |
3 | GTEx | Liver | NOTCH2 | 0.14 | 0.13 | lasso | 2 | 0.10 | 0.00076 | 5.4 | -5.5 | 4.2e-08 | -0.98 | 0.02 | 0.85 | TRUE |